Clinical trials: Knee Joint
Ischemia, Peripheral Arterial Disease (PTA
The ABSORB Bioresorbable Scaffold Below the Knee (BTK) Study
ABSORB BTK Study: A prospective, multicenter, controlled clinical evaluation of the use of a bioresorbable drug eluting stent in the arterial vasculature below the knee
- Conditions
- Ischemia, Peripheral Arterial Disease (PTA, Arterial Occlusive Diseases
- Trial name
- NCT02793349
- Testing
- Absorb Bioresorbable Vascular Scaffold
- Where
- 4 sites in Australia, Netherlands and 1 more
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Chronic Pain, Osteoarthritis
Effects of tDCS and tUS on Pain Perception in OA of the Knee
The purpose of this study is to investigate the effects of transcranial direct current stimulation (tDCS) in conjunction with transcranial ultrasound (TUS) on pain perception and functional limitations in people with…
- Trial name
- NCT02330315
- Testing
- transcranial direct current stimulation (tDCS), transcranial ultrasound (TUS)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Spaulding Rehabilitation Hospital
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament (ACL) Revision Surgery: French National Study
This is a national multicentric study led by the French Arthroscopy Society (SFA) evaluating clinical practice in anterior cruciate ligament (ACL) revision surgery (epidemiological data, morphological data, operative data…
- Trial name
- NCT06379308
- Testing
- questionaries, datas of medical record
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Osteoarthritis, Knee
Intraosseous With Intra-articular Injection of Platelet Rich Plasma in Treatment of Knee Osteoarthritis
The aim of this study was to compare the efficacy of treatment in three groups of patients with knee osteoarthritis (OA) given a combination of intraosseous with intra-articular injection of platelet rich plasma (PRP)…
- Trial name
- NCT03329235
- Testing
- PRP, HA
- Volunteers
- 86 people
- Sponsor
- Cangzhou Central Hospital
Hip Arthropathy, Knee Arthropathy
Effect of Vitamin D Status and Repletion on Postoperative Total Joint Arthroplasty Complications
Vitamin D status has been shown to have an effect on post-operative outcomes in total joint arthroplasty. The goal of this study is to determine if pre-operative supplementation and correction of Vitamin D deficiency can reduce…
- Conditions
- Hip Arthropathy, Knee Arthropathy, Vitamin D Deficiency
- Trial name
- NCT04229368
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Brigham and Women's Hospital
Knee Osteoarthritis
Assessment of Safety and Efficacy of ARTHRUM 2.5% for Treatment of Painful Osteoarthritis of the Knee
ARTHRUM 2.5% MONO-INJECTION as symptomatic treatment by joint injection extends the conservative therapeutic arsenal in Knee osteoarthritis.
- Trial name
- ART-ONE75 (NCT06228274)
- Testing
- ARTHRUM 2.5%
- Volunteers
- 218 people
- Sponsor
- LCA Pharmaceutical
Knee Arthritis
Oxford Unicompartmental Knee Arthroplasty With and Without Navigational Unit
The purpose of this study is to determine whether a computer navigational unit can improve operating time and consistency during Knee arthroplasty when compared to knee arthroplasty without a computer navigational unit.
- Trial name
- NCT00862316
- Testing
- Oxford Unicompartmental Knee
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Comparison Between Robotic-arm Assisted Total Knee Replacement and Traditional Total Knee Replacement
This is a multicenter, prospective, and case-control study. Five joint centers and 100 participants will be included. The study group used robotic-assisted modified kinematic alignment total knee replacement, and the control…
- Trial name
- NCT05391152
- Testing
- robotic assisted total knee replacement, traditional total knee replacement
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Knee Osteoarthritis, Arthroplasty Complications
Joint Awareness After Total Knee Replacement
Total knee replacement (TKR) is accepted as treatment of choice for end stage gonarthrosis. It is performed cemented or cementless and although cemented implants were shown to decrease bone density more than cementless fixations…
- Trial name
- NCT06033625
- Testing
- CEMENTLESS TOTAL KNEE REPLACEMENT
- Volunteers
- 150 people
- Sponsor
- Saglik Bilimleri Universitesi
Hernioplasty, Cholecystectomy, Laparoscopic
Intensive Monitoring of Post-surgery Pain in Major Ambulatory Surgery
Moderate to severe acute postoperative pain (APP) during part of the postoperative period is a barrier that hinders the central objective of perioperative medicine, which is to achieve an optimal postoperative recovery process.
- Conditions
- Hernioplasty, Cholecystectomy, Laparoscopic, Haemorrhoidal Surgery, Knee Arthroscopy
- Trial name
- NCT07252817
- Testing
- Intensive monioring group, Standard monitoring group
- Where
- Spain
- Volunteers
- 280 people
- Sponsor
- Consorci Sanitari del Maresme
Osteoarthritis, Knee
Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN
A previous multicenter trial led by Bioiberica S.A. has confirmed the efficacy and safety of DROGLICAN for the treatment of osteoarthritis (OA) in patients with severe pain.
- Trial name
- DRIP (NCT02821468)
- Testing
- Droglican, Paracetamol or oral NSAIDs excluding COX2 inhibitors
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Bioiberica
Evaluation of Polyethylene Wear After Failed TKA
RATE AND DISTRIBUTION OF WEAR OF EXPLANTED POLYETHYLENE INSERTS
The purpose of the study is to measure and compare the wear rates of retrieved PEI after failed TKA with respect to various causes for revision surgery, implant size, surgical and patient factors as well as to identify a…
- Trial name
- NCT05482438
- Testing
- Polyethylene
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- Valdoltra Orthopedic Hospital
Orthopedic Disorder
Accelerometry and Rehabilitation After Knee Replacement Study (ARK)
Total knee replacement (TKR) is a successful and cost-effective treatment for end-stage arthritis. Its usage is increasing due to changing population demographics and quality of life (QoL) expectations.
- Trial name
- ARK (NCT05412940)
- Testing
- Remote monitoring of home-based exercises following knee replacement using a wearable sensor, Standard Care (in control arm)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Arthropathy of Knee Joint
Regional Prophylactic Vancomycin With Restricted Tourniquet Time in Primary Total Knee Replacement
The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (the knee joint) is more effective at obtaining adequate tissue levels of the antibiotic than…
- Trial name
- NCT03506347
- Testing
- Vancomycin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Arthroplasty Complications, Total Knee Arthroplasty
Is Self-transfusion Safe After Total Knee Arthroplasty in Terms of Nephrotoxicity of Gentamicin From Bone Cement?
Considering that the high local concentration of antibiotic from bone cement is delivered intravenously through the self-transfusion process, systematic toxicity has never been evaluated.
- Trial name
- NCT04505748
- Testing
- Self-transfusion device
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University Hospital, Alexandroupolis
Anesthesia, Spinal, Arthroplasty, Replacement, Knee
Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty
The purpose of this study is to determine if a shorter-acting spinal anesthetic called mepivacaine has advantages over a longer-acting medication called bupivacaine.
- Conditions
- Anesthesia, Spinal, Arthroplasty, Replacement, Knee, Pain Management, Early Ambulation
- Trial name
- NCT02980926
- Testing
- Mepivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Anterior Cruciate Ligament Injury
A Novel Analgesia Technique for ACL Reconstruction
A comparison of two anesthetic techniques-- the Adductor Canal Block (ACB) and the Adductor Canal Block with Infiltration of the interspace between the popliteal artery and the capsule of the posterior knee (ACB/IPACK)-- in…
- Trial name
- NCT03292926
- Testing
- Bupivacaine, Ultrasound, Dexamethasone
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Hospital for Special Surgery, New York
Arthritis of Knee, Arthritis of Hip
Comparison of the Diagnosis Time of VET and SCL in Patients With Intraoperative Coagulopathy
The present study is a prospective, multi-center observational trial comparing the times taken to diagnose coagulopathies using point-of-care (POC) viscoelastic tests or standard central laboratory tests (SCL tests) in patients…
- Conditions
- Arthritis of Knee, Arthritis of Hip, Spine, Prostate Cancer
- Trial name
- NCT06637943
- Testing
- SCL tests, POC viscoelastic tests
- Where
- 4 sites in South Korea
- Volunteers
- 210 people
- Sponsor
- Konkuk University Medical Center
Arthroplasty, Replacement, Knee, Nerve Block
Does Continuous Adductor Canal Nerve Block Improve the Quality of Recovery for Outpatient Total Knee Arthroplasty Patients?
This is a randomized, double-blinded pilot study to determine whether patients undergoing ambulatory total knee arthroplasty (TKA) using a subvastus approach benefit from the addition of a continuous adductor canal nerve block…
- Conditions
- Arthroplasty, Replacement, Knee, Nerve Block, Anesthesia, Regional, Ambulatory Surgical Procedures
- Trial name
- NCT03038425
- Testing
- Normal Saline, Ropivacaine
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- Ottawa Hospital Research Institute