Clinical trials: Knee Osteoarthristis
Knee Osteoarthristis
ArtiBest for Knee Osteoarthritis
The goal of this clinical trial is to evaluate the real-world effectiveness and safety of ArtiBest in the treatment of knee osteoarthritis. The main questions it aims to answer are: 1.
- Trial name
- NCT06994546
- Testing
- ArtiBest ® Intra articular Injection
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Maxigen Biotech Inc.
Knee Osteoarthristis, Self Efficacy
Turkish Version of the Arthritis Self-Efficacy Scale-8
Self-efficacy is a psychosocial construct that reflects an individual's confidence in their ability to perform specific tasks, focusing more on one's belief in their abilities than on actual performance.
- Trial name
- T-ASES-8 (NCT06929741)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bezmialem Vakif University
Knee Osteoarthristis, Radiofrequency Ablation
Comparative Effectiveness of Genicular Nerve Radiofrequency Thermocoagulation and Intra-Articular Pulsed Radiofrequency in the Management of Knee Osteoarthritis Pain
Osteoarthritis (OA) is a degenerative disease characterized by progressive cartilage deterioration, osteophyte formation, subchondral sclerosis, and a number of biochemical and morphological changes in weight-bearing joints that…
- Trial name
- GNRFT & IAPRF (NCT07098455)
- Testing
- GNRFT- genicular nerve radiofrequency ablation, IAPRF- Intraarticular pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Ankara City Hospital Bilkent
Knee Osteoarthristis
Soft Knee Brace Versus Lateral Wedge in Knee Osteoarthritis
the aim of study is to investigate the efficacy of soft knee brace versus lateral wedge foot insole on pain and proprioception in knee OA
- Trial name
- NCT06836934
- Testing
- soft knee brace, lateral wedge foot insole, convential physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Knee Osteoarthristis
Evaluating the Impact of a Meta Quest 3 Gamified VR Rehabilitation Program in Knee Osteoarthritis
The goal of this clinical trial is to learn if a gamified virtual reality (VR) rehabilitation program can effectively reduce pain, improve functionality, and enhance balance in adults aged 40-64 years diagnosed with knee…
- Trial name
- NCT06735963
- Testing
- Meta Quest 3 Virtual Reality, Exercise, Electrotherapy
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Total Hip Arthroplasty (THA), Total Knee Arthroplasty (TKA)
Molecular Mechanisms Underlying Hip and Knee Osteoarthritis in Patients Undergoing Primary Elective Arthroplasty
The aim of this observational study is to determine content of rare metals and other elements, along with the levels of selected immunological parameters, in the tissue of the hip or knee joint in the course of degenerative…
- Conditions
- Total Hip Arthroplasty (THA), Total Knee Arthroplasty (TKA), Hip Osteoarthritis, Knee Osteoarthristis
- Trial name
- NCT07347821
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Warsaw
Knee Osteoarthristis
Robotic Medial Congruent Vs. Conventional Medial Pivot TKA
This multicenter, prospective cohort study will evaluate whether Robotic-Assisted total knee arthroplasty (RATKA) with a Medial Congruent implant is a successful method to improve implant alignment, insert thickness accuracy, and…
- Trial name
- NCT06858358
- Testing
- Robotic assisted total knee arthroplasty, Conventional total knee arthroplasty (cTKA)
- Where
- 2 sites in Romania
- Volunteers
- 300 people
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Knee Arthroplasty, Total, Knee Osteoarthristis
Knee Body Perception and Pain After Total Knee Arthroplasty
This observational study aims to better understand how knee pain and knee-specific body perception are related over time after total knee arthroplasty (knee replacement) for knee osteoarthritis.
- Trial name
- NCT07410884
- Where
- Japan
- Volunteers
- 285 people
- Sponsor
- Prefectural University of Hiroshima
Knee Osteoarthristis
Medication vs. Meditation for Chronic Knee Osteoarthritis
The purpose of this research study is to improve pain management for individuals with chronic knee osteoarthritis pain. Specifically, we are comparing the effects of a mindfulness meditation practice with those of oral…
- Trial name
- NCT07837284
- Testing
- Oral diclofenac potassium 50 mg, Mindfulness meditation
- Volunteers
- 30 people
- Sponsor
- Florida State University
Knee Osteoarthristis
Close Chain and Open Chain Exercises With Blood Flow Restriction in Knee Osteoarthritis
The aim of this research is to find and compare the effect of close chain and open chain exercises with blood flow restriction in knee osteoarthritis on pain, range of motion, strength and functional performance in patients with…
- Trial name
- NCT07426549
- Testing
- Closed kinetic chain exercises with blood flow restriction, Open kinetic chain exercises with blood flow restriction
- Where
- 2 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Knee Osteoarthristis
New Robotic Knee Surgery: Does Implant Type Affect Alignment Accuracy?
Total knee replacement is a common surgery for patients with severe knee arthritis. To improve surgical accuracy, surgeons now use robotic systems to help plan and perform the procedure.
- Trial name
- CAPTAIN (NCT07777757)
- Testing
- Attune Total Knee Implant, Persona Total Knee Implant
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Knee Osteoarthristis, Healthy Adults
Digital Course and Precision Rehabilitation for Knee Osteoarthritis and Older Adults: Integration of Multisensory Stimulation and Digital Twin Technology
Knee osteoarthritis (OA) is a common degenerative joint disease in middle-aged and older adults and is frequently associated with pain, quadriceps weakness, reduced mobility, impaired proprioception, balance deficits, and…
- Trial name
- NCT07695168
- Testing
- digital rehabilitation exercise courses combined with multisensory stimulation, Home exercises based on therapist education, Gait retraining combined with neuromuscular electrical stimulation
- Where
- 3 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Knee Osteoarthristis
The Validity and Reliability of the OMERACT in the Turkish Population
Knee osteoarthritis is a chronic disease common in middle-aged and older adults, characterized by functional impairment and reduced quality of life due to pain.
- Trial name
- NCT07416357
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir Democracy University
Knee Osteoarthristis
A Study to Investigate the Effectiveness, Safety, and Tolerability of MAG200 Solution for Intra-articular Injection Compared With Placebo in Participants Aged 35 to 75 Years of Age With Symptomatic Osteoarthritis of the Knee.
The purpose of this study is to confirm whether MAG200 (20M or 100M) will improve pain and function of participants with osteoarthritis of the knee compared with placebo. In addition, the two strengths of MAG200 will be compared.
- Trial name
- nexcell-OAK (NCT07106229)
- Testing
- allogeneic human adipose-derived mesenchymal stem cells
- Volunteers
- 573 people
- Sponsor
- Magellan Stem Cells
Knee Osteoarthristis
Integrative Chinese and Western Medicine for Knee Osteoarthritis
This study aims to investigate if an integrated approach combining Traditional Chinese and Western medicine can better treat knee osteoarthritis.
- Trial name
- NCT07072442
- Testing
- Western Medicine, herbal medicine and acupuncture, herbal medicine
- Volunteers
- 228 people
- Sponsor
- Chang Gung Memorial Hospital
Knee Osteoarthristis
Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis
Knee osteoarthritis (OA) affects an estimated 654 million people over age 40 world-wide. In the United States, approximately 16% of adults over the age of 40 have knee OA.
- Trial name
- NCT07652437
- Testing
- Dephy Exoboot
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Knee Osteoarthristis
Feasibility of Resting Intervals During Exercise Programs for Individuals With Knee Osteoarthritis
This pilot randomize trial tests the feasibility of administering two different exercise programs in people with knee osteoarthritis.
- Trial name
- CaRE (NCT06857123)
- Testing
- Exercise with Rest, Exercise without Rest
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Knee Osteoarthristis, Meniscus Injury
Hemi-tibial Plateau Osteotomy Combined With Arthroscopic Repair for Medial Meniscus Posterior Root Tears in Varus Knees
This is a single-center clinical trial started by the study team. The goal is to compare two surgeries for people who have a varus knee alignment and a tear at the back attachment of the medial meniscus.
- Trial name
- NCT07356674
- Testing
- Hemi-tibial plateau osteotomy combined with arthroscopic repair, High tibial osteotomy combined with arthroscopic repair
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University
Central Sensitization, Knee Osteoarthristis
Aquatic Exercise in Patients With Knee Osteoarthritis
The effect of aquatic exercise on central sensitization in patients with knee osteoarthritis are not fully known in the studies conducted to date.
- Conditions
- Central Sensitization, Knee Osteoarthristis, Aquatic
- Trial name
- NCT07883824
- Testing
- Standard physical therapy, Hydrotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Rehabilitation, Excercise
The ACT-ON: A Geriatric 5-Ms-Guided Physical Therapy Intervention for Knee Osteo-Arthritis in Older Adults.
The study is a Random control trail study conducted at King Khalid University Hospital in Riyadh, Saudi Arabia, focusing on Application of 5 framework in rehabilitation program of knee arthritis.
- Conditions
- Rehabilitation, Excercise, Geriatric, Physical Therapy
- Trial name
- 5Ms/PT/KOA/OA (NCT07640529)
- Testing
- Geriatric 5Ms framework, Exercises PT
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Saud University