Clinical trials: Knee Osteoarthristis, open to volunteers
Knee Osteoarthristis
Medication vs. Meditation for Chronic Knee Osteoarthritis
The purpose of this research study is to improve pain management for individuals with chronic knee osteoarthritis pain. Specifically, we are comparing the effects of a mindfulness meditation practice with those of oral…
- Trial name
- NCT07837284
- Testing
- Oral diclofenac potassium 50 mg, Mindfulness meditation
- Volunteers
- 30 people
- Sponsor
- Florida State University
Central Sensitization, Knee Osteoarthristis
Aquatic Exercise in Patients With Knee Osteoarthritis
The effect of aquatic exercise on central sensitization in patients with knee osteoarthritis are not fully known in the studies conducted to date.
- Conditions
- Central Sensitization, Knee Osteoarthristis, Aquatic
- Trial name
- NCT07883824
- Testing
- Standard physical therapy, Hydrotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Knee Osteoarthristis
Study NRPT Feasibility in Knee Osteoarthritis
To Evaluate Feasibility and Exploratory Clinical and Biomarker Signals of NRPT in Adults with Knee Osteoarthritis
- Trial name
- NRPT (NCT07917403)
- Testing
- NRPT
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Knee Osteoarthristis
Wearable Device Guided Exercise for Patients on Total Knee Arthroplasty Wait-list
Total knee arthroplasty (TKA) is a cost effective solution for people with end-stage knee osteoarthritis. Given Hong Kong's large senior population and age as the primary risk factor for osteoarthritis, waiting times for total…
- Trial name
- NCT07912333
- Testing
- Wearable Device, Control
- Where
- Hong Kong
- Volunteers
- 106 people
- Sponsor
- Chinese University of Hong Kong
Total Knee Arthroplasty, Knee Osteoarthristis
Application of Perinatal Derivatives in Total Knee Arthroplasty
This pilot study investigators whether the use of perinatal derivatives during knee replacement, in the form of an injection around the joint and patch over the knee joint incision, improves patient outcomes (including…
- Trial name
- NCT07908342
- Testing
- Intraoperative application of CTM Flow and CTM Thick, Total knee arthroplasty (TKA)
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Knee Osteoarthristis
Outpatient Physiotherapy vs. mHealth Exercise and Self-Management for Knee Osteoarthritis (MOKneeTOR)
Symptomatic osteoarthritis (OA) of the knee affects approximately one-fifth (~300K) of Singaporeans aged 50 years or older, with the disease prevalence increasing with age.
- Trial name
- MOKneeTOR (NCT07767409)
- Testing
- MOKneeTOR with standard app configuration, Hospital-based outpatient rehabilitation program, MOKneeTOR with standard app configuration and enhanced personalisation
- Where
- Singapore
- Volunteers
- 160 people
- Sponsor
- Singapore General Hospital
Knee Osteoarthristis, Hip Osteoarthritis
Clinical Validation of SMARTDIAGO for Remote Functional Assessment of Musculoskeletal Conditions
Clinical validation of SMARTDIAGO, an artificial intelligence-based system for remote functional assessment of patients with musculoskeletal disorders and functional frailty.
- Conditions
- Knee Osteoarthristis, Hip Osteoarthritis, Spine Disease, Shoulder Disease
- Trial name
- SMARTDIAGO (NCT07880210)
- Testing
- SMARTDIAGO Remote Functional Assessment
- Where
- 2 sites in Chile
- Volunteers
- 350 people
- Sponsor
- University of Chile
Joint Osteoarthritis, Knee Osteoarthristis
Clinical Evaluation of TrHCROSS® for Different Joints
This post-market clinical investigation is designed to evaluate the safety and effectiveness of TrHCROSS®, a CE-marked cross-linked hyaluronic acid viscosupplement, in patients with mild to moderate osteoarthritis of the knee…
- Conditions
- Joint Osteoarthritis, Knee Osteoarthristis, Hip Ostearthritis, Shoulder Osteoarthritis
- Trial name
- NCT07870031
- Testing
- TrHCROSS®, Monovisc
- Volunteers
- 150 people
- Sponsor
- i+Med S.Coop.
Knee Osteoarthristis, ACL Injuries
Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy
This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA).
- Conditions
- Knee Osteoarthristis, ACL Injuries, Post-Traumatic
- Trial name
- PTOA Knee (NCT06686680)
- Testing
- extracorporeal shockwave therapy (ESWT)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Spaulding Rehabilitation Hospital
Knee Osteoarthristis, Knee Pain Arthritis
Stimulation of Peripheral Afferents to Reduce Muscle Inhibition at the Knee
Knee osteoarthritis is a leading cause of disability, and the muscle weakness that limits walking in this population arises not only from the joint itself but from afferent signals that inhibit motor drive to the thigh muscle…
- Conditions
- Knee Osteoarthristis, Knee Pain Arthritis, Knee Pain Chronic
- Trial name
- SPARK (NCT07832669)
- Testing
- Peripheral Electrical Stimulation (PES), Paired Pulse Electrical Stimulation (ppES)
- Volunteers
- 50 people
- Sponsor
- Northeastern University
Knee Osteoarthristis
Gender Based Comparison of the Effects of Sensory Modulated Graded Weight Bearing Physiotherapy In Adults With Knee Osteoarthritis
This comparative experimental study aims to evaluate the effectiveness of Sensory-Modulated Graded Weight-Bearing Physiotherapy (SMGWBP) in patients with knee osteoarthritis and compare treatment outcomes between male and female…
- Trial name
- GSMGWBP (NCT07784998)
- Testing
- Sensory-Modulated Graded Weight-Bearing Physiotherapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Shifa Tameer-e-Millat University
Knee Osteoarthristis
BFR Training and Knee Osteoarthritis
Knee osteoarthritis (KOA) is a chronic, progressive degenerative joint disease characterized by cartilage and bone degeneration, synovial inflammation, and structural changes.
- Trial name
- NCT07590323
- Testing
- Standard Treatment, Pain neuroscience education, Blood flow restriction training
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- University of Hail
Rehabilitation, Excercise
The ACT-ON: A Geriatric 5-Ms-Guided Physical Therapy Intervention for Knee Osteo-Arthritis in Older Adults.
The study is a Random control trail study conducted at King Khalid University Hospital in Riyadh, Saudi Arabia, focusing on Application of 5 framework in rehabilitation program of knee arthritis.
- Conditions
- Rehabilitation, Excercise, Geriatric, Physical Therapy
- Trial name
- 5Ms/PT/KOA/OA (NCT07640529)
- Testing
- Geriatric 5Ms framework, Exercises PT
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Saud University
Knee Osteoarthristis, Obesity & Overweight
E-Health Lifestyle Intervention for Arthritis: A Pilot RCT on Feasibility
Knee osteoarthritis and obesity are common health problems in Hong Kong, especially among South Asian communities, where obesity rates are much higher than the general population.
- Trial name
- CHALAANE (NCT07786038)
- Testing
- Digital Health Intervention, Inactivated Smartband for Activity Monitoring
- Where
- 2 sites in Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Knee Osteoarthristis
New Robotic Knee Surgery: Does Implant Type Affect Alignment Accuracy?
Total knee replacement is a common surgery for patients with severe knee arthritis. To improve surgical accuracy, surgeons now use robotic systems to help plan and perform the procedure.
- Trial name
- CAPTAIN (NCT07777757)
- Testing
- Attune Total Knee Implant, Persona Total Knee Implant
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Knee Osteoarthristis, Cartilage Damage
Pilot Exploration of Platelet Characterization of Platelet Rich Plasma Created by Two Different Systems
The investigators would like to study the differences in the quality of Platelet Rich Plasma (PRP) between two different machines in those with knee osteoarthritis.
- Conditions
- Knee Osteoarthristis, Cartilage Damage, Platelet Rich Plasma, Platelet Rich Plasma Injection
- Trial name
- PRP-PEPC (NCT07491367)
- Testing
- Platelet Rich Plasma, Emcyte PurePRP Supraphysiologic Concentrating System, APEX Biologix XCELL PRP System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Knee Osteoarthristis
Sleep TO Prevent Post-surgical Pain
This research study is being done to compare different methods of addressing sleep problems before total knee replacement surgery. These methods include Cognitive Behavioral Therapy and light exposure.
- Trial name
- STOPPP (NCT06976138)
- Testing
- Cognitive-Behavioral Therapy for Insomnia, Bright Light therapy via the Re-Timer®, Negative Ion exposure via IonMi Device
- Where
- 2 sites in United States
- Volunteers
- 252 people
- Sponsor
- Johns Hopkins University
Knee Osteoarthristis, Diabetes (DM)
The NTU JO-SMART Study
This study recruits patients with coexisting obesity and knee osteoarthritis (KOA) to implement the NTU-JO Smart Program, an innovative intervention integrating AI-assisted community-based exercise with continuous glucose…
- Conditions
- Knee Osteoarthristis, Diabetes (DM), Obesity & Overweight, Chronic Kidney Disease
- Trial name
- NCT07317310
- Testing
- NTU-JO Smart Program
- Where
- 2 sites in Taiwan
- Volunteers
- 312 people
- Sponsor
- National Taiwan University Hospital
Knee Osteoarthristis
Close Chain and Open Chain Exercises With Blood Flow Restriction in Knee Osteoarthritis
The aim of this research is to find and compare the effect of close chain and open chain exercises with blood flow restriction in knee osteoarthritis on pain, range of motion, strength and functional performance in patients with…
- Trial name
- NCT07426549
- Testing
- Closed kinetic chain exercises with blood flow restriction, Open kinetic chain exercises with blood flow restriction
- Where
- 2 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Knee Osteoarthristis, Total Knee Replacement
Digitally Supported Short-Term Prehabilitation Before Total Knee Replacement
This study evaluates the feasibility of a short-term, digitally supported prehabilitation program for patients scheduled for elective total knee replacement (TKR).
- Trial name
- P2R-KneeTEP (NCT07621666)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Usual Care Group
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Ludwig Boltzmann Institute for Digital Health and Prevention