Clinical trials: Knee Osteoarthrosis
Hip Osteoarthritis, Knee Osteoarthritis
Prevalence,Natural History,Prognosis Factor,QualityofLife,Health Care Consumption and Social Consequences of Symptomatic Knee and Hip Osteoarthritis in France
The aim of the project is to assemble and to follow on a 10-year period a nationwide representative sample of lower limb OA patients.
- Trial name
- KHOALA (NCT00481338)
- Testing
- X-rays, biological samples, medical information about osteoarthritis
- Where
- 6 sites in France
- Volunteers
- 878 people
- Sponsor
- Central Hospital, Nancy, France
Bilateral Total Knee Arthroplasty, Gonarthrosis; Primary, Bilateral
Bilateral Simultaneous Total Knee Arthroplasty for Bilateral Gonarthrosis
The effects of two-team and single-team simultaneous bilateral total knee arthroplasty (SBA) on peri- and postoperative complications are not clear.
- Trial name
- NCT04299516
- Testing
- Two-team simultaneous bilateral total knee arthroplasty, Single-team simultaneous bilateral total knee arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 246 people
- Sponsor
- Bezmialem Vakif University
Osteoarthritis, Knee, Knee Pain Chronic
Finding the Optimal Aim of Correction in Opening Wedge High Tibial Osteotomy
The purpose of this RCT is to investigate whether high tibial osteotomy using 3D printed patient specific guides aiming at 55% correction is non-inferior to aiming at 62%.
- Conditions
- Osteoarthritis, Knee, Knee Pain Chronic, Arthralgia
- Trial name
- NCT06134050
- Testing
- Procedure: HTO using PSI aiming at 55% correction, Procedure: HTO using PSI aiming at 62% correction
- Volunteers
- 70 people
- Sponsor
- Vestre Viken Hospital Trust
Knee Osteoarthritis
Bespoke vs Standard Instrumentation in TKR
Total knee replacement (TKR) is an established treatment for knee osteoarthritis and leads to a satisfactory outcome in over 75% of patients.
- Trial name
- NCT02845206
- Testing
- Patient specific cutting blocks, Conventional cutting blocks
- Where
- United Kingdom
- Volunteers
- 172 people
- Sponsor
- NHS Lothian
Knee Pain
A Reliability and Validity Study of Urdu Version of Knee Outcome Survey-Activities of Daily Living Scale
The purpose of this study is to translate Knee Outcome Survey-Activities of Daily Living Scale into Urdu language and to check the reliability and validity of the Knee Outcome Survey-Activities of Daily Living Scale in Urdu…
- Trial name
- NCT05221047
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Riphah International University
OA Knee
Effects of Tai Chi Exercises on Patients Functional Status With Knee Osteoarthritis
Brief summary The goal of this clinical trial is to evaluate whether Tai Chi exercise, used as an adjunct to standard physiotherapy, can improve balance, functional status, pain, and knee joint mobility in older adults (65-75…
- Trial name
- NCT07428343
- Testing
- Tai Chi training, Comprehensive Inpatient Physiotherapy with other standard therapies, Kinect-Based Virtual Reality Balance Training with Biofeedback
- Where
- Poland
- Volunteers
- 96 people
- Sponsor
- Grzegorz Mańko
Knee Osteoarthritis (OA)
Instrument-Assisted Soft Tissue Mobilization as an Adjunct to Therapeutic Exercises in Individuals With Knee Osteoarthritis
To determine the efficacy of IASTM as an adjunct to therapeutic exercises on pain, range of motion, and functional performance in individuals with knee OA.
- Trial name
- NCT07710209
- Testing
- IATSM, Therapeutic Exercise
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Foundation of Medical Research and Laboratories, Pakistan
Osteoarthritis, Knee
A Single Time-Point Study to Evaluate the ConforMIS iTotal (PS) Knee Replacement System Versus Off-the-Shelf
This study is designed to compare outcome data for patients who have recently undergone surgery with the iTotal® Posterior Stabilizing (PS) Knee Replacement System (hereafter referred to as the "iTotal") versus those who have…
- Trial name
- NCT03146819
- Testing
- iTotal PS Knee Replacement System, Off-the-Shelf Knee Replacement System
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Restor3D
Osteoarthritis, Knee
Study to Evaluate the Safety and Efficacy of a Low Level Light Device in Patients With Knee Osteoarthritis
This Phase I study is being conducted to examine the efficacy of the Light Sciences LLC (LSLLC) phototherapy device for home (self) treatment of knee osteoarthritis (OA).
- Trial name
- NCT00375544
- Testing
- Low level light therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Light Sciences LLC
Knee Osteoarthritis
Non-surgical Treatment of Knee Osteoarthritis - a Comparison of Effects in 2200 Patients
The purpose of this study is to assess whether radiographic osteoarthritis severity (OA; Kellgren-Lawrence scale) is associated with self-reported improvement in pain after non-surgical treatments (physiotherapy, pain killers…
- Trial name
- NCT02091830
- Testing
- Paracetamol and nonsteroidal antiinflammatory drug (NSAID), Physiotherapy, Cortisone Injection
- Where
- Denmark
- Volunteers
- 2,262 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Knee Osteoarthritis
The Effect of Bike Exercise on Joint and Muscles
The design of our study is a prospective. It is planned to be completed in twenty-four weeks with 34 participants. The main purpose of this study is to examine and compare the effects of two different bike exercises on knee joint…
- Trial name
- NCT05564364
- Testing
- Recumbent Bike, Upright Bike
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mersin University
Osteoarthritis, Knee, Arthritis of Knee
Treatment of Knee Osteoarthritis With Allogenic Mesenchymal Stem Cells
In this study we want to evaluate the clinical use of allogenic mesenchymal stem cells (MSC), obtained from bone marrow of healthy donors, for treatment of knee osteoarthritis.
- Conditions
- Osteoarthritis, Knee, Arthritis of Knee, Knee Osteoarthritis
- Trial name
- MSV_allo (NCT01586312)
- Testing
- Allogenic mesenchymal stromal cells injection, Hyaluronic Acid
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- Red de Terapia Celular
Knee Osteoarthritis, Rheumatoid Arthritis
Computer Navigation vs Conventional Technique in Knee Arthroplasty
Project summary: Background: Computer navigation in knee replacement surgery is increasingly being used around the world, but the documentation of its usefulness is lacking.
- Trial name
- CAOS (NCT00782444)
- Testing
- Computer navigated knee replacement, Conventional knee replacement
- Where
- 4 sites in Norway
- Volunteers
- 192 people
- Sponsor
- Haukeland University Hospital
Osteoarthitis
Clinical Trial to Assess the Safety and Efficacy of Intra-articular Injection Collagen Versus Hyaluronic Acid on Knee Osteoarthritis
This study was designed to assess the efficacy for pain relief, functional improvement, and safety of intra-articular collagen injections compared to hyaluronic acid injections for knee osteoarthritis.
- Trial name
- NCT07511777
- Testing
- CartiZol, Synovian inj.
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Cellontech Co., Ltd.
Degenerative Joint Disease of Knee, Rheumatoid Arthritis
Intra-Articular Adelmidrol 2%/Hyaluronic Acid 1% With or Without m/umPEA, in Knee Pain Due to Joint Degeneration.
Degenerative knee joint diseases are characterized by chronic pain, inflammation, and functional impairment. In these conditions, mast cell density in the synovial membrane is increased, resulting in an excessive release of…
- Trial name
- NCT07680101
- Testing
- Adelmidrol 2% / Hyaluronic Acid 1%, micronized Palmitoylethanolamide (mPEA) 300mg + ultramicronized Palmitoylethanolamide (umPEA) 600mg
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Universita di Verona
Satisfaction
Prospective Trial of the TriFit™ Web Knee Brace
This is a prospective trial comparing improvements in pain, function, and quality of life in patients with early-stage knee osteoarthritis conservatively managed with the TriFit™ Web Knee Brace.
- Trial name
- NCT03633071
- Testing
- Web-knee brace
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Foundation for Orthopaedic Research and Education
Osteoarthritis
Evaluation of a New Formulation Useful for the Osteoarthrosis Treatment
Abstract Kondrium, is a pharmaceutical composition for the treatment of osteoarthritis (OA). This study was designed to evaluate the efficacy and safety of kondrium in the treatment of OA of knee.
- Trial name
- EFO (NCT00977444)
- Testing
- kondrium, kondrium f, methyl prednisolone (corticosteroid)
- Where
- Mexico
- Volunteers
- 114 people
- Sponsor
- Nucitec
Knee Osteoarthritis
Sensorimotor Training Versus Resistance Training in Patients With Knee Osteoarthritis
People with knee osteoarthritis (OA) have functional instability and defective neuromuscular function, it was recently suggested that sensorimotor exercises may be important and needed to improve the effectiveness of training…
- Trial name
- NCT01529398
- Testing
- Sensorimotor training (SMT), Resistance training (RT), Control group (CG)
- Where
- Brazil
- Volunteers
- 96 people
- Sponsor
- Federal University of São Paulo
Osteoarthritis, Knee, Osteo Arthritis Knee
Safety and Pharmacodynamics of GNSC-001 Intra-articular Injection for Knee Osteoarthritis
The goal of this clinical study is to determine if a single injection of 1 or more dose levels of adeno-associated virus (AAV) gene therapy (GNSC-001) is safe and tolerated compared to placebo in participants with painful…
- Conditions
- Osteoarthritis, Knee, Osteo Arthritis Knee, Knee Osteoarthritis
- Trial name
- DONATELLO (NCT05835895)
- Testing
- GNSC-001, transient immune-modulation
- Where
- 9 sites in United States
- Volunteers
- 67 people
- Sponsor
- Genascence Corporation
Osteoarthritis, Knee
Detecting Auricular Points in KOA by a Novel APD
This is a pilot diagnostic accuracy study conducted to assess the diagnostic ability of a novel APD for auricular point detection among patients with knee osteoarthritis (KOA), as compared with an already commercialized device.
- Trial name
- APD-KOA (NCT03702699)
- Testing
- Auricular point detector
- Where
- Hong Kong
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.