Clinical trials: Knee Osteoarthrosis
Meniscal Degeneration, Osteoarthritis of Knee
Evaluation of Clinical and Radiographic Outcomes of Meniscal Lesion Treatment Using Collagen Scaffolds (CMI)
Meniscal lesions represent the most frequently encountered joint pathology in the adult population and can cause pain symptoms, mechanical blockages, and recurrent effusions.
- Conditions
- Meniscal Degeneration, Osteoarthritis of Knee, Meniscus Injury
- Trial name
- SUPER CMI (NCT06597357)
- Testing
- Arthroscopy & saline irrigation alone
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis
Application of Radiostereometric Analysis (RSA) to Triathlon Knee Components Inserted Using the OtisMed Custom-fit Total Knee Replacement System
The OtisMed Custom-fit system for total knee replacements replaces conventional surgical techniques for templating and intra-operative instrumentation with a preoperative virtual surgery process that utilizes 3D models of the…
- Trial name
- NCT01262430
- Testing
- OtisMed, Computer Assisted Surgery (CAS)
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Dalhousie University
Knee Osteoarthritis, Older Women
Adding Group-Based Pain Neuroscience Education to a Community Exercise Program for Older Women With Knee Osteoarthritis
This pilot trial aimed to estimate preliminary clinical effects and to assess the feasibility of adding group-based pain neuroscience education (PNE) to exercise in women aged ≥60 years with medically diagnosed knee…
- Conditions
- Knee Osteoarthritis, Older Women, Pain, Disability
- Trial name
- NCT07565298
- Testing
- Pain neuroscience education (PNE), Exercise program
- Where
- Chile
- Volunteers
- 19 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Osteo Arthritis of the Knee
Research Title: Long Term Functional Outcome of a Single Hyaluronic Acid Injection in Improving Symptoms and Function in Patients With Knee Osteoarthritis - A Single-Arm Open-Label Study (DIART ONE).
This study aims to evaluate the effectiveness of a single HA injection in improving pain, function, and quality of life in patients with knee OA over a 12-month period.
- Trial name
- NCT07736781
- Testing
- Hyaluronic Acid (HA)
- Where
- Malaysia
- Volunteers
- 62 people
- Sponsor
- Universiti Sains Malaysia
Knee Arthropathy
Persona Cohort Nordic Multicenter Study
In this project the investigators wish to: Evaluate intra-operative and postop complications, longer term survivorship and patient reported outcome measures (PROMs) following primary total knee replacement using Persona Total…
- Trial name
- NCT03495232
- Testing
- Zimmer Biomet Persona total knee system
- Where
- 4 sites in Denmark, France and 2 more
- Volunteers
- 700 people
- Sponsor
- Zimmer Biomet
Osteo Arthritis Knee
MISHA Post-Market Clinical Study
Prospective evaluation of the safety and effectiveness of the MISHA Knee System. The study will collect data on the procedural and long-term adverse events, WOMAC pain and function scores, KSS satisfaction, subsequent surgical…
- Trial name
- NCT06118892
- Testing
- MISHA Knee System
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Moximed
Satisfaction
Prospective Trial of the TriFit™ Web Knee Brace
This is a prospective trial comparing improvements in pain, function, and quality of life in patients with early-stage knee osteoarthritis conservatively managed with the TriFit™ Web Knee Brace.
- Trial name
- NCT03633071
- Testing
- Web-knee brace
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Foundation for Orthopaedic Research and Education
Osteoarthritis
Determinants of Functional Ability, Perceived Health, and Interaction With Multimorbidity in Hip and Knee Osteoarthritis
Hip and knee osteoarthritis (OA) is an important health problem with a high prevalence and significant consequences on functional ability, perceived health, restriction of autonomy and handicap.
- Trial name
- PRO-ART (NCT02887092)
- Volunteers
- 881 people
- Sponsor
- Central Hospital, Nancy, France
Osteoarthritis
The Efficacy and Safety of Invossa K Injection in Patients Diagnosed With Knee Osteoarthritis
The purpose of this study is to evaluate the efficacy and safety of intraarticular Invossa K Injection patients diagnosed with Kellgren \& Lawrence grade 2 knee osteoarthritis.
- Trial name
- NCT03383471
- Testing
- Invossa K Inj.
- Where
- 17 sites in South Korea
- Volunteers
- 146 people
- Sponsor
- Kolon Life Science
Arthritis, Osteoarthritis
The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study
Adolescents and young adults who hurt their knees playing sports or doing recreational activities can develop joint damage, muscle weakness, inactivity, and weight gain which might lead to an increased risk of osteoarthritis…
- Conditions
- Arthritis, Osteoarthritis, Arthritis Knee, Osteo Arthritis Knee
- Trial name
- SOARPOC (NCT04956393)
- Testing
- Immediate 8-Week SOAR Program, Delayed 8-Week SOAR Program
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Knee Osteoarthritis
Effects of Textured Insoles on Balance, Physical Performance, and Plantar Pressure in Older Adults With Knee Osteoarthritis
This study aims to investigate the effects of textured insoles on balance, physical performance, and plantar pressure distribution in older adults with medial compartment knee osteoarthritis.
- Trial name
- TIKOA (NCT07097649)
- Testing
- Textured lateral wedge insole, Use of lateral wedge flat insole
- Volunteers
- 44 people
- Sponsor
- Esra Nur Turkmen
Gonarthrosis, Antioxidative Stress
Effects of Physical Therapy on Oxidative Stress in Female Patients With Gonarthrosis
This study aimed to investigate the production of reactive oxygen derivatives (ROS) and reactive nitrogen derivatives (RNT) in female patients with knee OA, and their effects on oxidative stress by evaluating before and after…
- Trial name
- NCT05731011
- Testing
- antioxidative stress, electrotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Baskent University
Knee Osteoarthritis, Arthritis
Inflammatory Response Conventional Total Knee Replacement Versus Mako Total Knee Replacement
Total knee Arthroplasty (TKA) is a highly effective treatment for knee osteoarthritis. Mid- to long-term follow-up studies have shown good clinical outcomes following TKA; despite these results, there is a high incidence of…
- Conditions
- Knee Osteoarthritis, Arthritis, Surgery
- Trial name
- NCT04192006
- Testing
- Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College, London
Osteoarthritis, Knee
Predictive Values for the Outcome of Genicular Nerve Radiofrequency Ablation for Chronic Knee Pain
Researchers are trying to assess a predictive value or correlation between patient and procedural characteristics and outcome measures results after genicular nerve radiofrequency ablation.
- Trial name
- NCT05222776
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people
- Sponsor
- Diskapi Teaching and Research Hospital
Osteoarthritis
The Impact of Total Knee Arthroplasty Surgical Technique on Coronal Plane Motion and PatelloFemoral Articulation
The purpose of this study is to examine the impact of two surgical techniques on the outcome of the knee replacement surgery.
- Trial name
- NCT01855906
- Testing
- Gap balanced surgical technique, Measured resection
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Knee Osteoarthritis
Robotic Assisted vs Custom Made Total Knee Arthroplasty
The goal of this clinical trial is to compare Robotic Assisted, functionally aligned vs Custom Made Total Knee Arthroplasty in patients with knee osteoarthritis.
- Trial name
- Knieathlon (NCT06280352)
- Testing
- Custom made Total Knee Arthroplasty, Functionally aligned robotically assisted total knee arthroplasty
- Where
- 2 sites in Austria
- Volunteers
- 120 people
- Sponsor
- Austrian Workers Compensation Board Styria
Osteoarthritis
Efficacy and Safety of Oral Salmon Calcitonin in Patients With Knee Osteoarthritis (OA 2 Study)
The purpose of this phase III study is to Evaluate the Efficacy and Safety of Oral Salmon Calcitonin in the Treatment of Patients with Osteoarthritis of the Knee
- Trial name
- NCT00704847
- Testing
- Oral Salmon Calcitonin
- Where
- 18 sites in United States, Belgium and 8 more
- Volunteers
- 1,030 people
- Sponsor
- Nordic Bioscience A/S
Osteoarthritis of Knee
The Recovery Time of Quadriceps Strength After Total Knee Arthroplasty (TKA): The Effect of Quadriceps Incision Length
Minimally invasive total knee arthroplasty (MIS-TKA) became the popular technique. It had the less postoperative pain and shorter recovery time compared to the conventional technique.
- Trial name
- NCT01450904
- Testing
- Quadriceps incision < 2 cm, Quadriceps incision 2-4 cm, Quadriceps incision > 4 cm
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Knee Osteoarthritis
Multimodal Evaluation of Cartilage Lesions of Patellofemoral Joint
Evaluation and comparison of histological analysis, 9,4 tesla MRI, Full-Field Optical Coherence Tomography (FFOCT) and ultrasound-based navigation system for cartilage degeneration analysis of patellofemoral joint.
- Trial name
- MULTICART (NCT03210584)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Grenoble
Osteoarthritis
Comparison of Quadriceps-sparing Minimally Invasive and Medial Parapatellar Total Knee Arthroplasty
Quadriceps-sparing minimally invasive total knee arthroplasty (TKA) with side-cutting instruments has been proposed to limit surgical dissection without compromising the surgical outcome.
- Trial name
- NCT01160835
- Testing
- total knee arthroplastyinstruments
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
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