Clinical trials: Knee Osteoarthrosis
Osteoarthritis
Meniscal Tear and Osteoarthritis Risk (MenTOR)
Adults with degenerative meniscal tear receiving arthroscopic surgical management or knee drainage (arthrocentesis) +/- intra-articular steroid injection will be recruited to this non-interventional cohort study.
- Trial name
- MenTOR (NCT02684864)
- Testing
- Non-interventional
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Oxford
Knee Osteoarthritis, Hip Osteoarthritis
The Kaia Hip and Knee Pain Intervention for Self-management of the Pain in Patients With Osteoarthritis.
The study intervention provides an innovative way of making exercise training and other recommended lifestyle modifications as accessible as possible for knee and hip OA participants by introducing a home-based exercise training…
- Trial name
- PIVOT (NCT04615377)
- Testing
- Kaia hip and knee pain application, Treatment as usual
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Kaia Health Software
Knee Osteoarthritis
Therapeutic Exercises for Pain and Disability in Knee Osteoarthritis
This study aims to evaluate the effectiveness of structured therapeutic exercises in reducing pain and disability among older adults diagnosed with knee osteoarthritis.
- Trial name
- OA (NCT07128875)
- Testing
- Exercise + TENS + Hot Pack, Exercise
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Bone Marrow Versus Adipose Tissue as a Cell Source for Infiltrative Treatment of Knee Osteoarthritis
The MAST-GR study is a randomized controlled interventional trial with parallel treatment arms and 1:1 allocation The primary objective of the study is to compare the safety and efficacy of a single intra-articular infiltration…
- Trial name
- NCT06040957
- Testing
- Bone marrow aspirate concentrate injection, intra-articular injection of Minimally manipulated adipose tissue
- Where
- Italy
- Volunteers
- 204 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis, Knee
A First-in-Human Study of XSTEM-OA in Patients With Knee Osteoarthritis
The aim of the study is to assess safety, tolerability and preliminary efficacy of XSTEM-OA when administered as a single intra-articular injection to patients with symptomatic knee osteoarthritis.
- Trial name
- NCT05344157
- Testing
- XSTEM-OA
- Where
- 2 sites in Australia
- Volunteers
- 24 people
- Sponsor
- Xindu Pty Ltd
Osteoarthritis, Knee
Reliability and Validity of Gait and Postural Balance Parameters
Knee osteoarthritis (KOA) patients, have impairments in gait and balance. Accurate gait and postural balance analysis is needed to detect this impairments.
- Trial name
- NCT02543736
- Testing
- Instrumented Treadmill System
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Osteoarthritis
"Score Infectivity" During Reoperation on Total Hip or Knee Prosthesis
The hip or knee is a validated treatment of end-stage osteoarthritis, and these interventions commonly make a significant improvement in the quality of life of patients. Infection can occur in 1-5% of cases.
- Trial name
- NCT02467764
- Testing
- Retrospective study
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Knee Osteoarthritis
THERAPEUTIC ULTRASOUND IN PATIENTS WITH KNEE OSTEOARTHRITIS
Knee osteoarthritis is a common condition that causes pain, stiffness, and reduced physical function. Therapeutic ultrasound is frequently used in physical medicine and rehabilitation to reduce pain and improve joint function in…
- Trial name
- NCT07323030
- Testing
- hot pack, transcutaneus electrical nerve stimulatıon, exersice terapy
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Knee Osteoarthritis
An Examination of the Value of Shortwave Diathermy and Hydrotherapy for Patients With Osteoarthritis of Their Knees
Osteoarthritis, a common disorder increasing in prevalence with advancing age, is particularly debilitating when the knees are affected.
- Trial name
- NCT00726492
- Testing
- Continuous short wave diathermy (CSWD), Hydrotherapy
- Where
- Ireland
- Volunteers
- 77 people
- Sponsor
- University College Dublin
Osteo Arthritis of the Knee
Hydrogel Assessment for Local Treatment of Osteoarthritis
The study aims to evaluate the safety and tolerability of one intra-articular injection of Hydrogel OA 2% for the symptomatic treatment of osteoarthritis of the knee.
- Trial name
- HALO (NCT07516457)
- Testing
- Injection of Hydrogel OA 2%
- Where
- 3 sites in Belgium
- Volunteers
- 20 people
- Sponsor
- Allegro NV/SA
Knee Osteoarthritis
Treatment of Early Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells
The purpose of this study is to explore the efficacy and safety of autologous adipose mesenchymal stem cells in the treatment of early knee arthritis.
- Trial name
- NCT03956719
- Testing
- Autologous adipose-derived mesenchymal stem cells, abdominal liposuction
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Qilu Hospital of Shandong University
Total Knee Arthroplasty (TKA)
Clinical Correlation of TKA Alignment and Native Knee Anatomy
Total knee arthroplasty (TKA) is still considered the treatment of choice for painful osteoarthritis. In the last decades neutral mechanical knee alignment in the coronal plane has been considered the gold standard.
- Trial name
- CAT (NCT05435092)
- Testing
- 3D-reconstruction CT
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- University Hospital, Basel, Switzerland
Knee Osteoarthritis
Foot and Hip Abductor Strengthening in Patients With Knee Osteoarthritis.
The study will be Randomized controlled trail, Subject diagnosed with knee osteoarthritis meeting predetermined inclusion and exclusion criteria will be divided into two groups.
- Trial name
- NCT06343909
- Testing
- Hip abductor strengthening exercise, Intrinsic foot muscle strengthening along with conventional exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Osteoarthritis of Knee, Recovery Following Primary Total Knee Arthroplasty
Perioperative Colchicine for TKA
This study is a prospective, randomized, double-blinded, placebo-controlled study of the drug colchicine in the acute postoperative period for patients who are undergoing a total knee arthroplasty (TKA).
- Conditions
- Osteoarthritis of Knee, Recovery Following Primary Total Knee Arthroplasty, Perioperative Pain Control
- Trial name
- NCT06936709
- Testing
- Colchicine 1.8 mg + 0.6 mg
- Volunteers
- 75 people
- Sponsor
- Geisinger Clinic
Knee Osteoarthritis, Pain
The Effect of Adding Instrumented Hip Concentric Abductor Strengthening Exercise in Knee Osteoarthritis
The aim of this study was to investigate the effectiveness of adding hip device-assisted concentric abductor strengthening (HDACAS) program to knee device-assisted concentric flexor-extensor strengthening (KDACFES) program on…
- Conditions
- Knee Osteoarthritis, Pain, Physical Disability
- Trial name
- NCT06331858
- Testing
- hip device-assisted concentric abductor strengthening (HDACAS), knee device-assisted concentric flexor-extensor strengthening (KDACFES)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kutahya Health Sciences University
Painful Osteoarthritis of the Knee
A Study of the Efficacy and Safety of MEDI7352 in Participants With Painful Osteoarthritis of the Knee
This is a Phase IIb randomised, double-blind, placebo-controlled, dose-response study in participants with painful osteoarthritis (OA) of the knee.
- Trial name
- BESPOKE (NCT04675034)
- Testing
- MEDI7352
- Where
- 41 sites in Denmark, Estonia and 4 more
- Volunteers
- 345 people
- Sponsor
- AstraZeneca
Knee Osteoarthritis
Comparative Evaluation of A-CP HA Kit, Hyaluronic Acid and Placebo for the Treatment of Knee Osteoarthritis
Hyaluronic acid (HA) is a major component of synovial fluid, to which it confers viscosity and elasticity. It has been shown that the rheological properties of the synovial fluid decrease in patients with osteoarthritis.
- Trial name
- NCT03201614
- Testing
- A-CP HA Kit, ArthroVisc 40
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Regen Lab SA
Osteoarthritis
A Study to Determine the Difference in Low Contact Stress (LCS) Duofix Versus Low LCS Porocoat Knee Systems
The primary objective of this investigation is to test the hypothesis that the Duofix Tibial component results in a reduction of immediate postoperative pain compared to the LCS Porocoat version.
- Trial name
- NCT00733499
- Testing
- LCS Complete Duofix, LCS Complete Porocoat
- Where
- Ireland
- Volunteers
- 206 people
- Sponsor
- DePuy International
Knee Osteoarthritis (OA)
Effects of Core Stabilization Exercises Versus Foot-Ankle Strengthening Program in Patients With Knee Osteoarthritis.
Knee osteoarthritis (OA) is also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage. It is most common in the elder population.
- Trial name
- NCT06658249
- Testing
- Core Stabilization Exercises with Foot-Ankle Strengthening Program, Foot-Ankle Strengthening Program
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Trochlear Thickness and Its Effect on the Outcomes of Total Knee Arthroplasty
Total knee arthroplasty (TKA ) is the gold standard treatment for advanced knee osteoarthritis. only 85% (75% to 92%) of patients with total knee arthroplasty are satisfied with their operations and 30% develops patellofemoral…
- Trial name
- NCT06555055
- Testing
- CT trochlear thickness change
- Where
- Egypt
- Volunteers
- 87 people
- Sponsor
- Ibrahim barsoum
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