Clinical trials: Knee Osteoarthrosis
Hip and Knee Osteoarthritis
Outcomes Data of Bone Marrow Stem Cells to Treat Hip and Knee Osteoarthritis
The purpose of this study is to determine if Bone Marrow Concentrate may be successful in the treatment of osteoarthritis. Bone Marrow Concentrate is known to contain a community of cells that has been shown to have…
- Trial name
- NCT01601951
- Testing
- Procedural, Bone Marrow concentrate injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Regenerative Pain Center, Illinois
Knee Osteoarthritis
Fu's Subcutaneous Needling Treatment for Knee Osteoarthritis
The population affected by degenerative knee arthritis is very large. The investigator performed Fu's subcutaneous needling (FSN).
- Trial name
- NCT04356651
- Testing
- Fu's subcutaneous needling(FSN), Transcutaneous Electric Nerve Stimulation
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- China Medical University Hospital
Osteoarthritis, Degenerative Joint Disease
Adding Value in Knee Arthroplasty Post-total Knee Replacement (TKR) Care Navigator Trial
The objectives of this research are to: Conduct a proof of concept randomized controlled trial with up to 300 patients undergoing primary total knee replacement (TKA) at Brigham and Women's Hospital (BWH).
- Trial name
- AViKA (NCT01540851)
- Testing
- Care Navigator, Standard Post-Operative TKA Care
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- Brigham and Women's Hospital
Osteoarthritis, Knee
Hip Joint Mobilizations and Strength Training in Patients With Knee OA Osteoarthritis
Knee osteoarthritis has been ranked 11th highest contributor to non-fatal burdens in the world. Many research studies have discussed the relationship of hip muscle with knee joint stating that impaired hip strength can be a…
- Trial name
- NCT04769531
- Testing
- Hip Joint Mobilizations, Hip joint Muscle strength training, knee strengthening and flexibility exercises
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Dow University of Health Sciences
Knee Osteoarthritis
Additional Effects of Steroid and Dextrose to Hyaluronic Acid on Knee Osteoarthritis
Using double-blind, randomized controlled design to compare the immediate, short-term and intermediate-term additional therapeutic effects of ultrasound-guided corticosteroid injection and dextrose injection of hyaluronic acid…
- Trial name
- NCT04165902
- Testing
- compare the effects of steroid plus hyaluronic acid and destrose plus hyaluronic acid on knee osteroarthritis
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University
Blood Flow Restriction
Vascular Occlusion for Optimizing Functional Improvement in Patients With Knee Osteoarthritis
Recent research in strength training physiology revealed that implementation of occlusion garments around the proximal aspect of the lower limbs in combination with low load strength training causes a reduced blood flow and thus…
- Trial name
- VOFIKO (NCT04996680)
- Testing
- Blood Flow Restriction (by using smart-cuff pro devices, acting as pressurized tourniquet) combined low load strengh training, Standardised low load strength training
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- University Hospital, Ghent
Knee Osteoarthritis
Benefits of Spa Therapy in Saint-Lary Soulan for Knee Osteoarthritis
The hypothesis is that the use of spa therapy in Saint-Lary Soulan for knee osteoarthritis treatment would have a therapeutic effect on this pathology.
- Trial name
- LARYTHERM (NCT05790824)
- Testing
- Spa therapy
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University of Bordeaux
Knee Osteoarthritis (Knee OA)
Exercise-induced Irisin in Individuals With Knee Osteoarthritis.
The goal of this prospective randomised controled study is to investigate the effect of 8-weeks brisk walking exercise on irisin levels, physical and psychosocial parameters in individuals with knee osteoarthritis, and the…
- Trial name
- Osteoarthritis (NCT06758388)
- Testing
- home exercise program, home exercise program + brisk walking exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ümmahani Kuş
Osteoarthritis
Qigong Therapy for Individuals With Knee Osteoarthritis
The purpose of this study is to evaluate the effectiveness of Qigong therapy, an ancient Chinese practice, for pain relief and symptom improvement in people with knee osteoarthritis (OA).
- Trial name
- NCT00104156
- Testing
- External Qigong therapy
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Knee Osteoarthritis
A Trial to Evaluate the Safety, Tolerability, and Efficacy of NCR100 Injection in the Treatment of Subjects With KOA
This clinical study is to investigate the safety and efficacy of NCR100 injection in subjects with knee osteoarthritis (KOA). It is a dose-escalating, open label study in adult KOA subjects.
- Trial name
- NCR100 (NCT06049342)
- Testing
- NCR100 injection
- Volunteers
- 12 people
- Sponsor
- Nuwacell Biotechnologies Co., Ltd.
Knee Arthritis Osteoarthritis
Clinical Observation and MRI Influence of Acupuncture on Knee Osteoarthritis
To observe the therapeutic effect of acupuncture on osteoarthritis(OA) and its efficacy on cartilage restoration,acupuncture and physiotherapy treatment were respectively given to two random groups.
- Trial name
- NCT02446756
- Testing
- acupuncture, physiotherapy
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Knee Osteoarthritis
Bespoke vs Standard Instrumentation in TKR
Total knee replacements are operations that are offered to patients who have severe arthritis pain that is affecting daily activities that is no longer controlled with painkillers.
- Trial name
- SPHERE (NCT05579951)
- Testing
- Patient specific instrumentation, Conventional
- Where
- United Kingdom
- Volunteers
- 172 people
- Sponsor
- Manchester University NHS Foundation Trust
Bilateral Knee Osteoarthritis
Gait, Stair Climbing and Postural Stability in Knee Osteoarthritis Patients After Hyaluronic Acid Injection
Treatment: five intro-articular Hyaluronic Acid injection Assessment has two parts, that are as follow: 1. Postural stability and risk of fall assessment using Biodex stability index and "Timed up and Go" test 2.
- Trial name
- NCT02063373
- Testing
- Hyaluronic acid
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Degenerative Arthritis, Knee Osteoarthritis
A Phase 3 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis
The purpose of this study is to investigate the efficacy and safety of autologous Adipose Tissue derived Mesenchymal stem cells (JOINTSTEM®) in patient with severe Knee Osteoarthritis.
- Trial name
- NCT03990805
- Testing
- JOINTSTEM, saline
- Where
- 13 sites in South Korea
- Volunteers
- 260 people
- Sponsor
- R-Bio
Osteoarthritis, Knee, Joint Instability
Prospective Post Market Clinical Follow-Up of the Primary Knee Endoprosthesis BPK-S Integration
Prospective, monocenter post market clinical follow-up of a primary knee replacement bearing the CE-mark. 200 subjects will be recruited and followed up for up to ten years or until revision of the primary knee endoprosthesis…
- Trial name
- NCT02615522
- Testing
- BPK-S Integration
- Where
- Austria
- Volunteers
- 124 people
- Sponsor
- Peter Brehm GmbH
Knee Osteoarthritis
TKA Using Patient-Specific Instrumentation
The purpose of our study is to determine if anatomic/kinematic total knee arthroplasties (TKAs) are superior to mechanical axis-referenced TKAs with respect to determinants of gait functionality, patient satisfaction and other…
- Trial name
- NCT03117959
- Testing
- Stryker ShapeMatch Technology, Stryker Triathlon Custom Fit Knee
- Where
- Canada
- Sponsor
- Queen's University
Postoperative Anemia, Knee Osteoarthritis
Effect of Postoperative Ferric Carboxymaltose
The primary purpose of this study is to evaluate the safety and efficacy of postoperative intravenous ferric carboxymaltose in patients with anemia undergoing Simultaneous Bilateral Total knee replacement in terms of Quality of…
- Conditions
- Postoperative Anemia, Knee Osteoarthritis, Total Knee Arthroplasty
- Trial name
- NCT03561480
- Testing
- Ferric carboxymaltose, 0.9% Normal Saline
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Degenerative Arthritis
Combined Administration of Intravenous and Topical Tranexamic Acid in Total Knee Arthroplasty
This prospective randomized controlled trial was conducted To compare the efficacy of TNA in terms of total blood loss and the allogenic transfusion rate among the three study groups; intravenous alone, combined intravenous and…
- Trial name
- NCT02286973
- Testing
- Tranexamic Acid
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Knee Osteoarthritis, Chronic Pain
Neurophysiological Mechanisms Involved in Knee Osteoarthritis
Introduction: Total knee arthroplasty (TKA) is an effective intervention to relieve people with osteoarthritis (OA). Nevertheless, 15 to 30% of patients continue to experience severe pain following surgery.
- Trial name
- NCT03556423
- Where
- 2 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Université de Sherbrooke
Necrosis of Femoral Head, Knee Osteoarthritis
MRI Maker of Perioperative Neurocognitive Disorder
Periperative neurocognitive disorder(PND) is consistently associated with increased morbidity and mortality, but its mechanisms remain unclear.
- Conditions
- Necrosis of Femoral Head, Knee Osteoarthritis, Fracture of Lower Limb
- Trial name
- MRIPND (NCT03773627)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
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