Clinical trials: Knee Osteoarthrosis
Osteoarthritis of the Knee
Efficacy of Aerobic Exercise Versus Therapeutic Exercises on Exercise-induced Hypoalgesia in Knee Osteoarthritis
The study compares two exercise strategies in people with knee osteoarthritis. The first is aerobic exercise on a recumbent cycle ergometer, with effort controlled by the Borg scale.
- Trial name
- NCT07302204
- Testing
- Aerobic Exercise, Therapeutic Exercise
- Where
- 2 sites in Brazil
- Volunteers
- 90 people
- Sponsor
- University of Nove de Julho
Knee Osteoarthritis
Randomized Trial in knEe Osteoarthritis Using Low Intensity Ultrasound - Evaluating Feasibility (RELIEF)
The purpose of this pilot study is to determine the feasibility of conducting a high quality clinical trial to investigate the effects of low intensity, pulsed ultrasound on knee osteoarthritis pain and physical function.
- Trial name
- RELIEF (NCT01623804)
- Testing
- low intensity, pulsed ultrasound
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- McMaster University
Knee Osteoarthristis
Feasibility of a Self-management App for People With Knee Osteoarthritis (OA-AID Feasibility Study)
In this feasibility trial, an 8-week digital intervention including remote monitoring in patients with knee osteoarthritis (OA) will be tested.
- Trial name
- NCT06656845
- Testing
- Genus, a self-management app for patients with knee osteoarthritis
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis
Community-Based Programs for Improving Physical Function in People With Early Knee Osteoarthritis
Osteoarthritis (OA) is the most common joint-related disease and most prevalent form of arthritis in the United States. Pain relievers and anti-inflammatory medications are the most commonly prescribed treatments for OA.
- Trial name
- NCT00586300
- Testing
- Physical training program, Self-management training program, Physical training and self-management training programs
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- University of Arizona
Osteoarthritis, Metal Ion Levels
Serum Metal Ion Concentration After Total Knee Arthroplasty (TKA)
All metal implants release metal ions because of corrosion. Total knee arthroplasty implants have large metal surface areas and therefore substantial potential for corrosion.
- Trial name
- NCT00862511
- Testing
- Coated Total Knee Arthroplasty, Standard Total Knee Arthroplasty
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Technische Universität Dresden
Osteoarthritis
A Study of Two Approved Drugs in Patients With Osteoarthritis (0966-220)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of osteoarthritis of the knee.
- Trial name
- NCT00092365
- Testing
- MK0966, rofecoxib
- Volunteers
- 413 people
- Sponsor
- Merck Sharp & Dohme LLC
Necrosis of Femoral Head, Knee Osteoarthritis
Ketamine Prevent POCD
Previous study demonstrated that neuroinflammation induced by surgery is the main cause of the postoperative cognitive dysfunction. As an agonist of NMDA receptor, ketamine is proved to be an anti-inflammation agent.
- Trial name
- KPPOCD (NCT02220400)
- Testing
- Ketamine
- Where
- 3 sites in China
- Volunteers
- 484 people
- Sponsor
- RenJi Hospital
Knee Osteoarthritis
An Examination of the Value of Shortwave Diathermy and Hydrotherapy for Patients With Osteoarthritis of Their Knees
Osteoarthritis, a common disorder increasing in prevalence with advancing age, is particularly debilitating when the knees are affected.
- Trial name
- NCT00726492
- Testing
- Continuous short wave diathermy (CSWD), Hydrotherapy
- Where
- Ireland
- Volunteers
- 77 people
- Sponsor
- University College Dublin
Osteoarthritis
A Randomized Control Trial to Assess Early Clinical and Functional Outcome of the ROCC and LCS Total Knee Implant Designs
This is a prospective Randomised Control Trial to compare the Early Clinical and Functional Outcome of the ROCC and LCS total knee arthroplasty implant designs.
- Trial name
- NCT00755144
- Testing
- LCS Knee, ROCC Knee
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet
Total Knee Replacement, Total Knee Replacement Surgery
Mako Cementless TKA vs Mako Cemented TKA
The overall aims of this prospective, randomised, single-blinded controlled trial are to compare functional, radiological and clinical outcomes in Mako robotic-arm assisted cementless Total Knee Arthroplasty (TKA) versus Mako…
- Conditions
- Total Knee Replacement, Total Knee Replacement Surgery, Total Knee Arthroplasty, Osteoarthritis (OA) of the Knee
- Trial name
- NCT06929871
- Testing
- Mako cementless TKA, Mako cemented TKA
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University College, London
Osteoarthritis, Knee
Efficacy and Safety of Intraarticular Sodium Hyaluronate Single Injection in Patients With Osteoarthritis of the Knee
A Phase III, prospective, multicentre, non-controlled, with consecutive participant enrollment in order to evaluate the efficacy, safety and duration of the effects of the viscosupplementation with a preparation of sodium…
- Trial name
- NCT03852914
- Testing
- Sodium hyaluronate 2%
- Where
- 10 sites in Spain
- Volunteers
- 93 people
- Sponsor
- Tedec-Meiji Farma, S.A.
Knee Osteoarthritis
The Arthritis, Diet, and Activity Promotion Trial
The primary purpose of this study was to determine the effect of dietary weight-loss, exercise training, or a combination of both on physical function in overweight and obese adults with knee osteoarthritis (OA).
- Trial name
- ADAPT (NCT00979043)
- Testing
- Dietary Weight-loss, Exercise
- Where
- United States
- Volunteers
- 318 people
- Sponsor
- Wake Forest University Health Sciences
Arthrosis
Changes in Physical Activity, Sleep and Knee Function After Same-Day Discharge Knee Arthroplasty
The goal of this observational study is to examine changes in physical activity, sleep quality, knee extension and flexion strength, knee range of motion, and patient-reported outcomes before and after same-day discharge knee…
- Trial name
- ORTOMOVE (NCT07840391)
- Testing
- Medial unicompartmental knee arthroplasty (UKA), Total knee arthroplasty (TKA)
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Knee Osteoarthritis, Knee Osteoarthritis (Knee OA)
Effect of Inspiratory Muscle Training on Knee Osteoarthritis Pain
Knee osteoarthritis (KOA) is a common joint disease that causes chronic pain and limits daily activities. Current treatments, such as painkillers or surgery, have limitations like side effects or high costs.
- Trial name
- NCT07698418
- Testing
- Inspiratory muscle training
- Volunteers
- 80 people
- Sponsor
- The Hong Kong Polytechnic University
Osteoarthritis, Osteoarthritis Knee Pain
Clinical Trial of Type II Collagen vs. Sodium Hyaluronate Intra-articular Injection in Knee Osteoarthritis
The purpose of this clinical trial is to evaluate the efficacy and safety of CartiSave compared with sodium hyaluronate in patients with knee pain.
- Conditions
- Osteoarthritis, Osteoarthritis Knee Pain, Knee Arthritis
- Trial name
- CartiSave (NCT07907926)
- Testing
- CartiSave, Hyalforte Injection
- Where
- 4 sites in South Korea
- Volunteers
- 117 people
- Sponsor
- ATEMs
Gonarthrosis
Routine Application of Ostenil® in Patients with Gonarthrosis
PMCF study to observe the routine application of Ostenil® in the treatment of pain and restricted mobility in degenerative and traumatic changes of the knee joint.
- Trial name
- NCT03734315
- Testing
- Ostenil®
- Where
- 6 sites in Germany
- Volunteers
- 115 people
- Sponsor
- TRB Chemedica AG
Osteoarthritis
Knee Injection RCT
Hypothesis: Ketorolac injection is a cost-effective adjunct in the nonoperative treatment of knee osteoarthritis (OA) compared to steroids and viscosupplementation.
- Trial name
- NCT03694821
- Testing
- Ketorolac Tromethamine Injection, Methylprednisolone Acetate Injection, Hylan G-F 20
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- UConn Health
Knee Osteoarthritis
Assessment of Efficacy of Low Intensity Resistance Training in Men at Risk for Symptomatic Knee Osteoarthritis
The purpose of this research study is to determine whether low intensity resistance training with concurrent application of a peripheral blood flow restriction device to the exercising limb will elicit increased quadriceps…
- Trial name
- PBFR3 (NCT01487525)
- Testing
- Double leg press with partial blood flow restriction, Double leg press without partial blood flow restriction
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Mild to Moderate Knee OA
Effects of Intra-articular Hypertonic Dextrose and Hyaluronic Acid on Primary Knee Osteoarthritis.
The aim of this study is to compare the effectiveness of intra-articular hypertonic dextrose and hyaluronic acid in managing pain and improving function in patients with primary knee osteoarthritis (KOA).
- Trial name
- NCT07102225
- Testing
- prolotherapy solution of 20% dextrose, Hyaluronic Acid (HA)
- Where
- Bangladesh
- Volunteers
- 56 people
- Sponsor
- Bangladesh Medical University
Osteoarthritis, Knee
Influence of Osteoarthritis Information on Treatment Beliefs
The aim of this study is to evaluate the effect of educational information, with and without a general practitioner recommendation to exercise, on willingness to undertake exercise/physical activity for knee osteoarthritis.
- Trial name
- NCT04698655
- Testing
- Information on treatment options, Recommendation from general practitioner, Information on osteoarthritis
- Where
- Australia
- Volunteers
- 735 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.