Clinical trials: Knee Osteoarthrosis
Knee Osteoarthritis
Effects of MWM Vs Sustained Mobilization on Knee Osteoarthritis
This article focused on people diagnosed with grade III Knee OA with sample size of 68 patients , who will randomly divided into two groups .
- Trial name
- MWM (NCT07315464)
- Testing
- mulligan moblization, kaltenborn moblization
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Osteoarthritis, Knee
A Phase 1/2A, Single Dose Study Of PF-04383119 In Japanese Patients With Moderate To Severe Pain From Osteoarthritis Of The Knee
To evaluate the safety and tolerability of single IV doses of PF-04383119 in Japanese patients with moderate to severe pain from OA of the knee (Part I).
- Trial name
- NCT00669409
- Testing
- PF-04383119 (tanezumab)
- Where
- 12 sites in Japan
- Volunteers
- 83 people
- Sponsor
- Pfizer
Osteoarthritis
Comparison of Two Application Regimens for Viscosupplementation
Viscosupplementation by intra-articular injection of hyaluronate products has recently gained popularity as a treatment modality of gonarthritis.There is not, however, a consensus on the best method.Our objective is to evaluate…
- Trial name
- NCT01824485
- Testing
- viscosupplementation 1+1+1, viscosupplementation 3 at once
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- University of Sao Paulo General Hospital
Knee Osteoarthritis
The Efficacy and Safety of Intraarticular Sodium Hyaluronate (Hyalgan) After Proximal Tibial Osteotomy in Treatment of Knee Osteoarthritis Patients
The purpose of this study is to assess the efficacy and safety of Hyalgan after proximal tibial osteotomy in treatment of knee osteoarthritis patients.
- Trial name
- NCT01267214
- Testing
- Sodium Hyaluronate (Hyalgan), Osteotomy alone
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- TRB Chemedica
Knee Osteoarthritis
Custom Guides for Total Knee Arthroplasty (TKA)
The goal of the study is to know if the reconstruction of the lower limb mechanical axis and the patient knee function is improved after Total Knee Arthroplasty (TKA) using patient specific instruments.
- Trial name
- NCT01573208
- Testing
- Custom guides
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Lausanne Hospitals
Osteoarthritis
Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP)
This is a multi-phase study that will develop and test an osteoarthritis (OA) primary care Physical activity Care Pathway (OA-PCP), a scalable intervention that includes: 1) a practical process for physical inactivity screening…
- Trial name
- NCT03780400
- Testing
- Osteoarthritis Physical Activity Care Pathway
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoarthritis
Efficacy of Eccentric Resistance Training in Persons With Knee Osteoarthritis
The purpose of this study is to determine if there are differences in balance, strength, functional performance and self-reported outcomes for subjects with knee osteoarthritis who complete a low intensity, long duration…
- Trial name
- NCT02350387
- Testing
- High Intensity Short Duration Exercise, Low intensity Long Duration Exercise
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Regis University
Patella-Dislocation, Patellofemoral Osteoarthritis
A Prospective Randomized Study of Medial Patellofemoral Ligament (MPFL) Reconstruction
The operative management of chronic patellar instability has been controversial. Medial patellofemoral ligament reconstruction has gained success recently and might be superior to other soft-tissue procedures.
- Conditions
- Patella-Dislocation, Patellofemoral Osteoarthritis, Patellar Instability
- Trial name
- NCT00816647
- Testing
- Patellofemoral stabilizing surgery
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Finnish Defense Forces
Gonarthrosis, Knee Osteoarthritis
Efficacy of Craniosacral Therapy in Patients With Gonarthrosis
This randomized controlled trial was designed to investigate the effects of craniosacral therapy on pain, heart rate variability, joint stiffness, physical function, quality of life, body image, kinesiophobia, and dynamic balance…
- Trial name
- NCT07372534
- Testing
- Craniosacral Therapy, Home-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ankara Yildirim Beyazıt University
Knee Osteoarthritis, Joint Disease
Multi-variable Prediction Model of Total Knee Replacement Outcome
Total knee arthroplasty (TKA) is a surgical procedure applied as a common solution to overcome limitations produced by advanced stages of severe gonarthrosis.
- Conditions
- Knee Osteoarthritis, Joint Disease, Total Knee Replacement, Arthroplasty Complications
- Trial name
- NCT03894514
- Where
- Spain
- Volunteers
- 243 people
- Sponsor
- University of Valencia
Osteoarthritis, Knee, Knee Arthritis
Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid
The research study aims to evaluate the synovial fluid to highlight the presence of possible micropolymers (micro/nanoplastics) in order to better understand the pathophysiology of joint degenerative processes.
- Conditions
- Osteoarthritis, Knee, Knee Arthritis, Gout Arthritis, Microcrystal Disease
- Trial name
- NCT05678049
- Testing
- Synovial fluid analysis
- Volunteers
- 50 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Knee Osteoarthritis
Study to Evaluate the Digestive Tolerability of ART44 Versus ART®50 in Patients With Osteoarthritis of the Knee
The primary objective of this study, comparing ART 44 to ART 50, will be the evaluation of digestive tolerability (and in particular of diarrhoea).
- Trial name
- NCT01009671
- Testing
- ART 44, ART 50
- Volunteers
- 210 people
- Sponsor
- Laboratoires NEGMA
Osteoarthritis of the Knee
Efficacy and Safety Study of Glucosamine/Chondroitin Sulfate to Patients Treatment With Osteoarthrosis of the Knee
The purpose of this study is to assess the efficacy and safety of glucosamine and chondroitin sulfate association in the treatment of patients with osteoarthrosis of the knee.
- Trial name
- Artico (NCT00955552)
- Testing
- Glucosamine sulphate and chondroitin sulphate association, Cosamin DS® (Nutramax)
- Where
- 4 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- Eurofarma Laboratorios S.A.
Knee Osteoarthritis
Perineural Dextrose Versus Local Anesthetic Injections in Knee Osteoarthritis
This prospective observational study aims to compare the clinical effectiveness of perineural 5% dextrose injections and perineural local anesthetic injections in patients with symptomatic knee osteoarthritis.
- Trial name
- NCT07381621
- Testing
- Perineural 5% Dextrose Injection, Perineural Local Anesthetic Injection
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ankara Training and Research Hospital
Osteoarthritis Of Knee
Evaluation Protocol of the Installation of Knee Unicompartmental Prosthesis (Journey (Smith & Nephew)) With Mechanical Ancillary Versus Robotic Assisted (Navio System).
Unicompartmental knee arthroplasty by unicompartmental prosthesis (PUC) is a treatment for isolated internal femoro-tibial osteoarthritis.
- Trial name
- PUC NAVIO (NCT03469193)
- Testing
- internal PUC implanted with mechanical ancillary, Internal PUC implanted with robotic assistance
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Hospices Civils de Lyon
Osteoarthritis, Knee
Strongest Predictors of a Positive Outcome After Physiotherapy for Knee Osteoarthritis
Individuals with painful knee osteoarthritis (OA) experience restricted physical function. Few previous studies have investigated comprehensive sets of constructs and tests to investigate physical function in these patients.
- Trial name
- NCT03113149
- Where
- Norway
- Volunteers
- 3 people
- Sponsor
- Norwegian University of Science and Technology
Osteoarthritis, Knee
A Locally Injected Bradykinin Antagonist for TReatment of OSteoarthritiS
The purpose of this study is to determine whether intra-articular (knee joint) administration of MEN16132 is effective reducing the pain from knee osteoarthritis.
- Trial name
- ALBATROSS (NCT01091116)
- Testing
- MEN16132 - 0.125 mg, MEN16132 - 0.25 mg, MEN16132 - 0.5 mg
- Where
- 23 sites in France, Germany and 2 more
- Volunteers
- 423 people
- Sponsor
- Menarini Group
Osteoarthritis
Prediction of Outcomes Following Total Knee Replacement
This is an observational study (not a treatment study) of pain and physical functioning after total knee replacement. The study includes 5 visits, 1 before surgery and 4 after surgery.
- Trial name
- POKR (NCT01370421)
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Brigham and Women's Hospital
Osteoarthritis, Knee
Ketoprofen in Transfersome Compared to Oral Celecoxib and Placebo for Pain Associated With Osteoarthritis of the Knee
The purpose of this study is to determine the safety and effectiveness of 110 mg ketoprofen in Transfersome applied to the skin twice daily as compared to placebo and oral celecoxib 200 mg per day for the relief of signs and…
- Trial name
- NCT00317733
- Testing
- Ketoprofen in Transfersome
- Volunteers
- 360 people
- Sponsor
- IDEA AG
Knee Osteoarthritis, Deformity Knee
Long Term Evaluation of Clinical and Radiologic Results on Femoro-patellar Joint After High Tibial Osteotomy
Osteotomies are among the oldest orthopedic treatments, in use for over 2000 years and still commonly employed. The basic principle involves making a bone cut to allow the realignment of the limb segment affected by deformity.
- Trial name
- NCT06251752
- Testing
- X-rays: load bearing inferior limbs, lateral knee, axial patella
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
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