Clinical trials: Knee Replacement Arthroplasty
Knee Osteoarthritis, Knee Arthroplasty
Development of an Outcome Score for Patients With Knee Osteoarthritis and Knee Joint Endoprosthesis Using an App
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) is one of the most frequent orthopedic procedures. Over 50% of patients report higher expectations than their surgeons, and 10-50% remain dissatisfied…
- Conditions
- Knee Osteoarthritis, Knee Arthroplasty, Hip Osteoarthritis, Hip Arthroplasty
- Trial name
- KneeApp (NCT07212699)
- Testing
- KneeApp
- Where
- Germany
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Total Knee Arthroplasty
Comparison Between Brainlab Knee 3 Computer-assisted Navigation Systems and Conventional Instruments in TKA: a Prospective Cohort Study.
This is a a prospective cohort study. According to the inclusion criteria, volunteers were recruited from patients undergoing total knee arthroplasty.
- Trial name
- NCT04960345
- Testing
- Brainlab Knee 3
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Osteoarthritis, Knee
Reinflation After Early Tourniquet Release in Total Knee Arthroplasty
This study is aimed to determine the efficacy and the safety of the tourniquet reinflation after early tourniquet release in total knee arthroplasty, compared to the method of early deflation without reinflation.
- Trial name
- NCT01832272
- Testing
- Reinflation after early tourniquet deflation
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Seoul National University Hospital
Pain and Mobility Levels of Patients Undergoing Total Knee Prosthesis During Continuous Passive Motion Exercise, Total Knee ArthroplastyKnee Pain, Functionality
Stress Ball and Hand Holding on Pain After Knee Arthroplasty
Pain after Total Knee Arthroplasty. (TKA) is an important problem When pain is not controlled, it can negatively affect the patients; mobility level.This research; A randomized controlled experimental design was planned to…
- Trial name
- NCT06608264
- Testing
- Stress Ball, Hand Holding
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Necmettin Erbakan University
Complications; Arthroplasty
A Comparison Between an Individual Low Tourniquet Pressure Versus a Standard Pressure During Total Knee Arthroplasty
The use of bloodless field is a helpful and important method in orthopedic surgery. The surgery can be done without interrupting bleedings, while keeping an exact overlook of the anatomy.
- Trial name
- NCT01442298
- Testing
- Limb occlusion pressure (LOP), conventional measurement method
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Charlotta Olivecrona
Knee Osteoarthritis
The Effects of Surgical Wait Time for Knee Arthroplasty Quality of Life in Patients Awaiting Knee Arthroplasty
This study prospectively evaluates the effect of surgical wait time on knee function, pain and quality of life in patients waiting for knee arthroplasty (TKA or PKA)
- Trial name
- SIT'NWAIT (NCT06127719)
- Testing
- questionnaires
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Dijklander Ziekenhuis
Prevention of Arterial and Venous Thrombosis
A Clinical Study of SHR-2004 Injection in Preventing Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty
The purpose of the study is to evaluate the efficacy and safety of SHR-2004 in preventing venous thromboembolism after elective unilateral total knee arthroplasty.
- Trial name
- NCT06825416
- Testing
- SHR-2004 injection, Enoxaparin sodium injection
- Where
- 2 sites in China
- Volunteers
- 1,165 people
- Sponsor
- Beijing Suncadia Pharmaceuticals Co., Ltd
Total Knee Arthroplasty, Total Knee Arthroplasty Recovery
Femoral Triangle Block vs Adductor Canal Block on Early Quadriceps Function After Total Knee Arthroplasty
The goal of this clinical trial is to compare the effects of femoral triangle block (FTB) and adductor canal block (ACB) on early quadriceps function after total knee arthroplasty (TKA).
- Conditions
- Total Knee Arthroplasty, Total Knee Arthroplasty Recovery, Total Knee Arthroplasty Postoperative Pain
- Trial name
- NCT07524387
- Testing
- Femoral Triangle Block (FTB) Group, Adductor Canal Block (ACB) Group
- Where
- Japan
- Volunteers
- 136 people
- Sponsor
- Social Medical Corporation Daiyukai
Hip or Knee Surgery
Post Market Clinical Follow-up Study
The overall rationale for this study is to evaluate the clinical performance potential for Mepilex Border Post-Op in the ability to minimise the risk of blistering, maceration and less dressing change due to high absorption…
- Trial name
- MxB Po01 (NCT01841567)
- Testing
- Mepilex border post. op, Mepilex border post op
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Molnlycke Health Care AB
Total Knee Arthroplasty, Knee Pain
Optimizing Local Anesthetic Concentration for Continuous Femoral Nerve Blocks
This is a randomized, observer-masked, controlled study. Subjects will be patients undergoing bilateral total knee arthroplasty (TKA).
- Trial name
- NCT00923598
- Testing
- 0.1% and 0.4% perineural ropivicaine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of California, San Diego
Resistance Training, Stroke
The Effect of Isokinetic Strengthening Training
Our participants will include 40 patients within one month of stroke, 43 patients who received total hip replacement or total knee replacement two to four weeks before.
- Conditions
- Resistance Training, Stroke, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT02938416
- Testing
- Isokinetic strengthening exercise, Isotonic strengthening exercise, isometric strengthening exercise
- Where
- Taiwan
- Volunteers
- 126 people
- Sponsor
- Taichung Veterans General Hospital
Total Knee Replacement, Reliability and Validity
Reliability and Validity of the 2-Minute Step Test in Patients With Knee Arthroplasty
Total knee arthroplasty (TKA) is a cost-effective treatment for end-stage knee osteoarthritis. It has demonstrable benefits such as reducing pain and improving activity and quality of life.
- Trial name
- NCT05064943
- Testing
- 2-minute step test
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Kutahya Health Sciences University
Degenerative Joint Disease
Comparison of A Mobile-Bearing Total Knee System With A Fixed-Bearing Total Knee System In Cemented Total Knee Arthroplasty
Pain, weakness, instability, and progressive dysfunction are the hallmarks of arthritis of the knee. Total knee replacement may frequently be the only therapeutic intervention to provide adequate improvement in pain and function.
- Trial name
- NCT00589108
- Testing
- Sigma Knee System, Sigma Pressfit Condylar Posterior Cruciate Substituting System with a metal back tibial tray, Sigma Pressfit Condylar Posterior Cruciate Substituting System all polyethylene tray
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Mayo Clinic
Osteoarthritis, Rheumatoid Arthritis
Comparison of Rotating vs. Fixed Platform of the COLUMBUS Knee Prosthesis
A population of 100 patients randomised to rotating and fixed PE inlays in the Columbus knee prosthesis received a navigated TKR.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic; Arthrosis
- Trial name
- NCT00822640
- Testing
- Total Knee Arthroplasty
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Aesculap AG
Hip Prosthetic Surgery, Knee Prosthetic Surgery
Development of a Predictive Algorithm for a Hemoglobin Value of Less Than 10 g/dl Postoperatively in Scheduled Hip or Knee Arthroplasty
Hip (THR) or knee (KT) prosthetic surgery is a bleeding surgery with an average blood spoliation of about 1 liter and an average decrease of about 3 g/dl in hemoglobinemia (Hb).
- Trial name
- Predi_Hb (NCT05605860)
- Where
- France
- Volunteers
- 1,041 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Arthroplasty, Replacement, Knee, Synovectomy
Synovectomy in Primary Total Knee Arthrplasty
The aim of total knee arthroplasty is to achieve best patient functional outcomes, improve patient pain score and satisfaction. Synovial proliferation is a common finding in arthritic knees.
- Trial name
- NCT03778463
- Testing
- Synovectomy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Arthroplasty, Replacement, Knee
Traditional vs Oral Fluid Management in Total Knee Arthroplasty
Purpose: Evidence-based guidelines on optimal perioperative fluid management have not been established in patients undergoing orthopaedic surgery.
- Trial name
- NCT03719378
- Testing
- Pre Operative Oral Fluids
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Colorado Joint Replacement
Total Knee Arthroplasty
Intraosseous (IO) Cefazolin and Vancomycin in Primary Total Knee Arthroplasty (TKA)
The goal of this clinical trial is to compare the efficacy of intravenous (IV) and intraosseous (IO) antibiotic administration techniques during primary total knee arthroplasty (TKA) in adults undergoing a TKA procedure at…
- Trial name
- NCT06640491
- Testing
- IO Administration of Cefazolin, IO Administration of Vancomycin, IV Administration of Cefazolin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Methodist Hospital Research Institute
Joint Diseases, Arthritis Knee
Anterior Knee Pain in Mobile Bearing Versus Fixed Bearing in TKA
Osteoarthritis is the most common cause of chronic joint disease, and its incidence has increased due to the high average life expectancy, in addition to the high incidence of obesity.
- Conditions
- Joint Diseases, Arthritis Knee, Arthroplasty Complications
- Trial name
- NCT05696418
- Testing
- Total knee arthroplasty with a Mobile Bearing system., Total knee arthroplasty with a Fixed Bearing system.
- Where
- Syria
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Damascus University
Surgery, Cataract
Routine Surgical Procedures During COVID-19 Pandemic: a French Nationwide Cohort Study
Determine the consequences of COVID-19 pandemic on routine targeted surgeries. Five surgical procedures were considered : cataract surgery, hip and knee arthoplasties, coronary revascularisation by angioplasty and definitive…
- Conditions
- Surgery, Cataract, Hip Arthroplasty, Knee Arthroplasty
- Trial name
- NCT05197660
- Testing
- surgical procedures
- Where
- France
- Volunteers
- 2,000,000 people
- Sponsor
- EPI-PHARE
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