Clinical trials: Knee Rheumatism
Knee Osteoarthritis, Sensation Disorders
The Effect of Cycle Ergometer With Biofeedback on Deep Sensation in Elderly Patients With Knee Osteoarthritis
The aim of the randomized controlled study is to investigate the effects of the cycle ergometer with biofeedback on deep sensation in elderly people who has knee osteoarthritis
- Trial name
- NCT05836792
- Testing
- Cycle Ergometer, Transcutaneous electrical nerve stimulation, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Nilay Aral
Osteoarthritis
Study to Compare Prescription Non-Steroidal Anti-Inflammatory Drug (NSAID) Changes, Health Care Utilization, Efficacy and Safety of Meloxicam 7.5 mg Versus Usual Care Administration of Prescription NSAIDs in a Managed Healthcare Setting in Patients With Osteoarthritis
Study to compare the percentage of treatment successes or failures in patients randomized to meloxicam 7.5 mg vs. usual care prescription NSAIDs.
- Trial name
- NCT02183064
- Testing
- Meloxicam, NSAID
- Volunteers
- 1,309 people
- Sponsor
- Boehringer Ingelheim
Osteoarthritis
Comparing Fixed-bearing Versus Mobile-bearing Prosthesis in Total Knee Arthroplasty: A Prospective Randomized Trial
The purpose of this study is to determine which prosthesis is better in total knee arthroplasty
- Trial name
- NCT01312532
- Testing
- fixed-bearing (P.F.C.® Sigma), mobile-bearing (P.F.C.® Sigma)
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Rheumatoid Vasculitis With Rheumatoid Arthritis of Knee, Unilateral Post-Traumatic Osteoarthritis of Knee
JOURNEY II XR Safety and Effectiveness PMCF
This study was designed to demonstrate the safety and performance of the JOURNEY II XR total knee system by evaluating implant survival rates at 10 years using Kaplan-Meier analysis.
- Conditions
- Rheumatoid Vasculitis With Rheumatoid Arthritis of Knee, Unilateral Post-Traumatic Osteoarthritis of Knee, Knee Osteoarthritis, Degenerative Arthritis Peripheral Joint
- Trial name
- NCT03136887
- Testing
- JOURNEY II XR Total Knee System
- Where
- 14 sites in United States
- Volunteers
- 176 people
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis of the Knee, Insomnia
Sleep, Pain and Inflammatory Processes in Older Adults With Osteoarthritis
The purpose if the study is to determine whether improving sleep, especially slow wave or "deep" sleep, in older adults with osteoarthritis (OA) and insomnia reduces pain sensitivity and inflammatory responses to pain, and…
- Conditions
- Osteoarthritis of the Knee, Insomnia, Knee Pain
- Trial name
- NCT01683799
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Rochester
Osteoarthritis of the Knee
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
The purpose of this study is to test whether surgical insertion of total knee replacement provides further improvement in quality of life, pain and function in addition to an algorithm for systematic non-surgical treatment…
- Trial name
- MEDIC (NCT01410409)
- Testing
- Neuromuscular training (NEMEX-TJR), Paracetamol, Burana
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Osteoarthritis, Knee, Knee Osteoarthritis
Study to Evaluate Intra-articular Resiniferatoxin to Treat Moderate to Severe Pain From Knee Osteoarthritis
This study evaluates the efficacy and safety of a single IA injection of various RTX doses, Zilretta or placebo for the treatment of pain due to moderate to severe osteoarthritis knee pain..
- Conditions
- Osteoarthritis, Knee, Knee Osteoarthritis, Knee Pain Chronic
- Trial name
- NCT04885972
- Testing
- Resiniferatoxin, Zilretta
- Where
- 6 sites in United States
- Volunteers
- 124 people
- Sponsor
- Sorrento Therapeutics, Inc.
Chronic Knee Osteoarthritis
Ultrasound-guided Radiofrequency Ablation of the Genicular Nerve Versus Physical Therapy for Chronic Knee Osteoarthritis
The aim of this study is to compare the effects of conventional physiotherapy methods with ultrasound-guided radiofrequency ablation of the genicular nerve on pain and functional status in patients with stage 2-3 chronic knee…
- Trial name
- NCT06173830
- Testing
- radiofrequency ablation, physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara City Hospital Bilkent
Osteoarthritis, Knee
Open Ended Trocar vs. Fenestrated Blunt Trocar in Bone Marrow Aspirate for Osteoarthritis
Osteoarthritis (OA) is a leading cause of disability around the world. The aging population is only further increasing its prevalence.
- Trial name
- NCT03579407
- Testing
- BMA cell therapy injection
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Advanced Orthopaedic Specialists
Knee Osteoarthritis, Total Knee Arthroplasty
Comparison of TKAs Using Force Plate Analysis
The purpose of this study is to evaluate performance of two modern total knee arthroplasty designs using patient reported outcomes and force exhibited during various activities of daily living.
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Knee Injuries, Knee Arthritis
- Trial name
- NCT04163445
- Testing
- MicroPort Orthopedics EVOLUTION Medial Pivot TKA, Depuy Synthes ATTUNE PCR TKA
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Russell Nevins, M.D.
Osteoarthritis, Osteoarthritis, Knee
Post-market Follow up Study of the 'BPK-S Integration' UC as Primary Implant in the Variants CoCr or Ceramic
Prospective Post-Market Clinical Follow up study according to MEDDEV 2.12/2 rev2 of the European Union. Patients receiving the primary knee implant BPK-S UC as primary implant in either variant ceramic or CoCr (metal) are…
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Joint Instability, Arthritis
- Trial name
- NCT03293719
- Testing
- BPK-S Integration UC
- Where
- Austria
- Volunteers
- 28 people
- Sponsor
- Peter Brehm GmbH
Osteoarthritis, Osteoarthritis, Knee
A Clinical Trial Investigating the Effect of Salmon Bone Meal on Osteoarthritis Among Men and Women
The purpose of this study is to evaluate the efficacy of hydrolyzed collagen in osteoarthritis.
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT05070871
- Testing
- Hydrolyzed Collagen, CalGo
- Where
- 3 sites in Norway
- Volunteers
- 98 people
- Sponsor
- Hofseth Biocare ASA
Knee Osteoarthritis
Evaluation of Mobility in Subjects With Severe Knee Osteoarthritis Who Are to Undergo Total Knee Replacement
Osteoarthritis (OA) is the most common joint disease. It is characterized by a progressive destruction of all the components of the joint, especially the cartilage.
- Trial name
- MOUV-GOPRO (NCT05488093)
- Testing
- X-sens sensor
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Knee Osteoarthritis
Clinical Trial of Low-dose Radiation Therapy in Patients With Knee Osteoarthritis (LoRD-KNeA Trial)
Clinical verification of knee osteoarthritis pain relief and functional improvement using low-dose radiation therapy
- Trial name
- LoRD-KNeA (NCT05562271)
- Testing
- low-dose radiation therapy
- Where
- 3 sites in South Korea
- Volunteers
- 114 people
- Sponsor
- Seoul National University Hospital
Knee Osteoarthritis, Cartilage Degeneration
Impact of High Tibial Osteotomy in Preventing Degenerative Disease Progression in Medial Knee Osteoarthritis.
High tibial osteotomy (HTO) surgical procedure can lead to clinically significant improvements in the cartilage and in subchondral bone quality, with a slow down of the osteoarthritis (OA) progression.
- Conditions
- Knee Osteoarthritis, Cartilage Degeneration, Malalignment, Bone
- Trial name
- HTO-IOR (NCT05865899)
- Testing
- valgus producing medial opening wedge high tibial osteotomy
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis
DePuy Attune Total Knee Arthroplasty RSA Study
The DePuy Attune knee system incorporates several key features aimed at improving kinematics of the knee joint, range of motion, and smoothness of use compared to existing total knee replacement technologies.
- Trial name
- NCT02103504
- Testing
- DePuy Attune posterior stabilized fixed bearing total knee replacement
- Where
- 3 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Michael Dunbar
Osteoarthritis (OA) of the Knee, Knee Pain Arthritis
Imageless Navigation Versus Image-Based Navigation in Robotic-Assisted Total Knee Arthroplasty for Knee Osteoarthritis
The goal of this clinical trial is to learn if imageless navigation is not inferior to image-based navigation in robotic-assisted total knee arthroplasty (RA-TKA) for treating patients with knee osteoarthritis.
- Conditions
- Osteoarthritis (OA) of the Knee, Knee Pain Arthritis, Total Knee Arthroplasty (TKA), Robotic Assisted Arthroplasty
- Trial name
- NCT07522489
- Testing
- Imageless Robotic-Assisted Total Knee Arthroplasty, Image-based Robotic-Assisted Total Knee Arthroplasty
- Where
- Poland
- Volunteers
- 146 people
- Sponsor
- Medical University of Warsaw
Osteoarthritis
Comparison of Function and Fit of Standard and Gender-Specific CR High-Flex Total Knee Prostheses
The purpose of this prospective, randomized study was to compare functional outcome, radiographic results, range of motion, patients satisfaction, and fit of the femoral component in patients receiving either a standard posterior…
- Trial name
- CR (NCT00916968)
- Testing
- Standard CR-Flex total knee, Gender specific CR-Flex
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Ewha Womans University
Osteoarthritis
Comorbidities and Indirect Health State Utility in Hip and Knee Osteoarthritis
National cohort study aimed to investigate the impact of comorbidities (number and type of comorbidities) on health utility state change in lower lim osteoarthritis (hip and knee OA).
- Trial name
- COMUTAR (NCT02879890)
- Volunteers
- 878 people
- Sponsor
- Central Hospital, Nancy, France
Knee Osteoarthritis
Physical Therapy Versus Internet-Based Exercise Training for Patients With Knee Osteoarthritis
The purpose of this study is to examine the effectiveness of standard physical therapy and an internet-based exercise program for people with knee osteoarthritis (OA).
- Trial name
- PATH-IN (NCT02312713)
- Testing
- Internet Based Exercise Training, Physical Therapy
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of North Carolina, Chapel Hill