Clinical trials: LAM
Acute Myelogenous Leukemia
Vaccination by Leukemic Apoptotic Corpse Autologous Pulsed Dendritic Cells for Acute Myelogenous Leukemia (AML) Patients in First or Second Complete Remission (CR)(CD laM)
Dendritic cells vaccinations are increasingly used in order to develop antitumoral immune response. This will be a Phase 2 trial using autologous dendritic cells pulsed with leukemic apoptotic corpse in acute myelogenous leukemia…
- Trial name
- CD lam (NCT01146262)
- Testing
- cell therapy product, injection of the cell therapy product
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Nantes University Hospital
HIV Infections
The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs
To evaluate the safety and tolerance of adefovir dipivoxil and indinavir administered orally in combination with zidovudine, lamivudine, or stavudine in HIV-infected patients with CD4 cell counts >= 100 cells/mm3 and an HIV-1 RNA…
- Trial name
- NCT00002379
- Testing
- Indinavir sulfate, Levocarnitine, Adefovir dipivoxil
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 100 people
- Sponsor
- Gilead Sciences
HIV Infections
Safety and Effectiveness of an Anti-HIV Drug Combination Taken Twice Daily
The purpose of this study is to see whether taking indinavir (IDV) plus ritonavir (RTV) plus stavudine (d4T) plus lamivudine (3TC) 2 times each day is safe and can lower the level of HIV in the blood.
- Trial name
- NCT00002241
- Testing
- Indinavir sulfate, Ritonavir, Lamivudine
- Where
- 18 sites in United States
- Volunteers
- 80 people
- Sponsor
- Merck Sharp & Dohme LLC
HIV Infections
A Comparison of Nelfinavir Plus Saquinavir Plus Delavirdine or 3TC/ZDV Versus Nelfinavir Plus 3TC/ZDV in HIV-Infected Patients
To compare the long-term virologic response to combination therapy with two protease inhibitors, i.e., nelfinavir (NFV) + saquinavir soft gel capsule (SQVsgc) and delavirdine (DLV) or combination lamivudine/zidovudine (3TC/ZDV…
- Trial name
- NCT00001094
- Testing
- Lamivudine/Zidovudine, Nelfinavir mesylate, Saquinavir
- Where
- 17 sites in United States, Puerto Rico
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infection, HIV Infections
Prevention of Lipoatrophy in Patients Treated With Lopinavir/Ritonavir in Monotherapy Versus ZDV + 3TC + ABC
The aim of this study is to measure the prevention of lipoatrophy in patients treated with Lopinavir/R in monotherapy versus ZDV + 3TC + ABC
- Trial name
- KALIPO (NCT00865475)
- Testing
- AZT+3TC+ABV (Trizivir), Switching to LPV/r monotherapy (Kaletra)
- Where
- 7 sites in Spain
- Volunteers
- 38 people
- Sponsor
- Fundacion SEIMC-GESIDA
HIV-1-infection
Cellular Pharmacology and Platelet Effects of Abacavir and Lamivudine Anabolites
This study will evaluate the intracellular pharmacokinetics and platelet effects of abacavir (ABC), lamivudine (3TC), tenofovir alafenamide (TAF), and emtricitabine (FTC) in persons living with HIV that are receiving these…
- Trial name
- NCT04301661
- Testing
- Blood collection, Abacavir/lamivudine, Tenofovir alafenamide/emtricitabine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Colorado, Denver
SMD
GFM-Acadesine: A Phase I-II Trial of Acadesine
A phase I-II trial of Acadesine in IPSS high and int 2 myelodysplastic syndromes, acute myeloid leukemia with 20-30% marrow blasts and chronic myelomonocytic leukemia type 2 not responding to Azacitidine or Decitabine for at…
- Trial name
- Acadesine (NCT01813838)
- Testing
- ACADESINE 140mg/kg/d, ACADESINE 210mg/kg/d, ACADESINE 315mg/kg/d
- Where
- 17 sites in France
- Volunteers
- 5 people
- Sponsor
- Groupe Francophone des Myelodysplasies
HIV Infections
A Phase II Open-Label Exploratory Study of Saquinavir + Zidovudine + Lamivudine in HIV Infected Patients
To explore the antiviral efficacy, tolerability and safety of saquinavir plus zidovudine plus lamivudine.
- Trial name
- NCT00002190
- Testing
- Saquinavir, Lamivudine, Zidovudine
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Hoffmann-La Roche
HIV Infection
Good-first: B/F/TAF As First-line ART
This is a multicohort study conducted at Affiliated Hospital of Nantong University, and Nantong Third Peoples Hospital (Designated Hospital for HIV/AIDS Treatment of Nantong City), China.
- Trial name
- NCT06619288
- Testing
- B/F/TAF, TDF+3TC+EFV, DTG/3TC
- Where
- China
- Volunteers
- 630 people
- Sponsor
- Affiliated Hospital of Nantong University
Kidney Failure, Chronic
A Long Term Study of Lanthanum Carbonate in Patients Requiring Dialysis Who Have Ived Lanthanum Carbonate in Previous Studies Defined by the Protocol.
The purpose of this study is to assess the safety of lanthanum carbonate in patients undergoing dialysis who have received lanthanum carbonate in the previous studies and wish to continue treatment.
- Trial name
- NCT00150540
- Testing
- Lanthanum carbonate
- Volunteers
- 93 people
- Sponsor
- Shire
HIV Infection
Evaluation of a Maintenance Strategy With Protease Inhibitors With or Without Lamivudine in Virologically Suppressed HIV Patients on Second Line Antiretroviral Treatment in Africa
Multicenter, randomized, superiority trial to evaluate efficacy of a mono or bi-therapy of protease inhibitors with or without lamivudine over a period of 96 weeks. The primary outcome will be the failure rate at 96 weeks.
- Trial name
- MOBIDIP (NCT01905059)
- Testing
- monoPI - boosted lopinavir or boosted darunavir, bi therapy - (boosted lopinavir or boosted darunavir) + lamivudine
- Where
- 5 sites in Burkina Faso, Cameroon and 1 more
- Volunteers
- 265 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV/AIDS, Osteoporosis
Preventing Bone Loss Among Chinese Patients With HIV on ART
The major goal of this study will be to conduct a randomized, double-blind, placebo-controlled, clinical trial of intermittent high-dose vitamin D3 supplementation (180,000IU) given at the point of care (every 3 months) after…
- Conditions
- HIV/AIDS, Osteoporosis, Bone Loss
- Trial name
- NCT03598556
- Testing
- Vitamin D3
- Where
- 6 sites in China
- Volunteers
- 600 people
- Sponsor
- Peking Union Medical College Hospital