Clinical trials: LBP, open to volunteers
Hypotension During Surgery
The Hypotension Prediction Index in Major Abdominal Surgery
The goal of this randomized clinical trial is to compare different types of advanced hemodynamic monitoring in patients undergoing major abdominal surgery.
- Trial name
- NCT06247384
- Testing
- Hypotension Prediction Index Hemodynamic Monitoring
- Where
- Poland
- Volunteers
- 226 people
- Sponsor
- Jakub Szrama
Anesthesia
A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia
The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery.
- Trial name
- NCT05954832
- Testing
- Echocardiography
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hypotension After Spinal Anesthesia, Hypotension During Cesarean Delivery
Comparison of the Efficacy of Continuous Metaraminol Infusion Versus Continuous Norepinephrine Infusion for the Prevention of Hypotension During Cesarean Section Under Spinal Anaesthesia. A Randomised Controlled Trial.
The aim of this double-blind randomised study will be to compare a fixed-rate prophylactic metaraminol infusion to a fixed-rate prophylactic norepinephrine infusion during elective cesarean section under combined spinal-epidural…
- Trial name
- NCT07363109
- Testing
- Metaraminol infusion, Norepinephrine infusion
- Volunteers
- 80 people
- Sponsor
- Aretaieion University Hospital
Dry Eye Syndromes
Efficacy of Lycium Barbarum Polysaccharide in Dry Eye Disease Management
The goal of this pilot clinical study is to learn if Lycium barbarum polysaccharide (LBP) supplementation helps manage dry eye disease in adults. It will also learn about the safety of LBP supplementation.
- Trial name
- NCT07842536
- Testing
- Lycium Barbarum Polysaccharide
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Geriatric Population, Spinal Anesthesia Induced Hypotension
HEIGHT-BASED AND CONVENTIONAL SPINAL ANAESTHETIC DOSING IN GERIATRIC PATIENTS
The goal of this clinical trial is to find out whether height-based dosing of spinal anaesthesia provides better hemodynamic stability and anesthetic outcome than conventional fixed dosing in elderly patients undergoing lower…
- Conditions
- Geriatric Population, Spinal Anesthesia Induced Hypotension, Spinal Anesthesia in Elderly Patients
- Trial name
- NCT07363941
- Testing
- Group A : Spinal Anaesthetic Dose, Group B : Conventional Dose
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Hypotension, Neonatal Hypotension
Appropriate Dosage of Vasopressor in Neonates and Infants
In this study, the investigators will evaluate cerebral blood flow before and after drug infusion using ultrasound to suggest blood pressure criteria and dosage of ephedrine, a vasopressor, to maintain adequate cerebral blood…
- Conditions
- Hypotension, Neonatal Hypotension, Intraoperative Complications
- Trial name
- NCT06257316
- Testing
- EPHEDrine Hydrochloride 5 mg/ml
- Volunteers
- 132 people
- Sponsor
- Seoul National University Hospital
Ultrasound, Machine Learning
Intelligent Classification of Intraoperative Hemodynamic Phenotypes Based on CADFlow Doppler Monitoring
The goal of this observational study is to learn about intraoperative hemodynamic phenotypes in adult patients undergoing elective surgery under general anesthesia, using a new wearable ultrasound patch (CADFlow) that…
- Conditions
- Ultrasound, Machine Learning, Intraoperative Hypotension, Hemodynamic Monitoring
- Trial name
- NCT06957587
- Where
- 2 sites in China
- Volunteers
- 440 people
- Sponsor
- Shanghai 6th People's Hospital
TURP(Transurethral Resection of Prostate), Spinal Anesthesia
Modified Saddle Block vs Spinal Anesthesia for TURP
After obtaining informed consent, eligible patients will be enrolled in the study. Standard monitoring will be applied in the operating room and baseline blood pressure and heart rate will be recorded.
- Conditions
- TURP(Transurethral Resection of Prostate), Spinal Anesthesia, Saddle Block Anesthesia, Hypotension During Surgery
- Trial name
- NCT07841184
- Testing
- Saddle block, Spinal Anesthesia (bupivacaine)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Septic Shock, Sepsis
Effects of Dexmedetomidine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock
This prospective, multicenter, single-arm, open-label interventional pilot study aims to evaluate the short-term physiological effects of intravenous dexmedetomidine on sublingual microcirculation and vascular-waterfall…
- Conditions
- Septic Shock, Sepsis, Critical Illness
- Trial name
- DEX-MICRO (NCT07657715)
- Testing
- Dexmedetomidine Intravenous Infusion
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Low Back Pain (LBP)
Telerehabilitation in Managing Chronic Low Back Pain
The purpose of this study is to determine whether telerehabilitation is as effective as in-person rehabilitation in treating patients with chronic back pain in actual clinical practice settings.T he study will recruit eighty-four…
- Trial name
- NCT06844825
- Testing
- Tele rehabilitation, usual care only
- Volunteers
- 84 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Post-induction Hypotension
Evaluation of the Relation Between Patient Fasting Time and the Occurrence of PIH (Post Induction Hypotension)
This monocentre prospective trial aims to evaluate the relationship between fasting time and the occurence of PIH (post-induction hypotension).
- Trial name
- NCT07785635
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Ostrava
Vasodilatory Shock
Synthetic Angiotensin II/Giapreza in Pediatric Patients With Refractory Hypotension
The goal of this clinical trial is to determine the safety and efficacy of Angiotensin-II in the treatment of pediatric patients in fluid refractory vasodilatory shock.
- Trial name
- NCT07212686
- Testing
- Angiotensin-II
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Thoracic Paravertebral Block, Anesthesia Induction
The Impact of Ultrasound-Guided Superficial and Deep Paravertebral Nerve Blocks at the Superior Costotransverse Ligament on Hemodynamics During the Induction Phase of Thoracoscopic Lung Lobectomy: A Multicenter, Double-Blind, Randomized Controlled Trial
This study aims to determine whether performing a paravertebral nerve block at the superficial surface of the superior costotransverse ligament (SCTL) (without needle penetration of the SCTL) is more effective in maintaining…
- Conditions
- Thoracic Paravertebral Block, Anesthesia Induction, Hypotension on Induction
- Trial name
- NCT06841822
- Testing
- SCTL superficial plane block, SCTL deep plane block group
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Post Induction Hypotension
Machine Learning Model Based on Baroreflex Sensitivity for Predicting Post-Induction Hypotension in Elderly Patients
The purpose of this study is to develop a high-performance machine learning model combining dynamic baroreflex sensitivity (BRS) metrics and multi-dimensional static clinical features to predict the risk of post-induction…
- Trial name
- NCT07618416
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking Union Medical College Hospital
Arterial Puncture, Radial Artery Injury
Blood'up Device Versus Manual Palpation for Arterial Puncture in Healthy Volunteers: A Pilot Randomized Study Under Normal and Simulated Hypotension
Arterial puncture is a common procedure in the management of hospitalized patients. It is most often performed at the level of the radial artery and allows arterial blood gas analysis.
- Conditions
- Arterial Puncture, Radial Artery Injury, Hypotension, Healthy
- Trial name
- NCT07765199
- Testing
- Arterial blood gas, Simulated hypotension, Arterial Puncture using Blood'Up device
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Hypotension, Orthostasis
Clinical Trial of Digital Therapeutics (One.Dr) for Suspected Orthostatic Hypotension Patients
Participants who meet the inclusion/exclusion criteria in the Screening visit are randomly assigned 1:1 to the treatment group or the sham control group.
- Trial name
- NCT07348445
- Testing
- Digital therapeutics (One.Dr Application)
- Volunteers
- 86 people
- Sponsor
- Yonsei University
Post-Dural Puncture Headache, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Predictive Value of ONSD and NIRS for PDPH
Currently, there is no reliable and effective method available in clinical practice to predict the development of PDPH. Early prediction and prevention of PDPH would reduce the incidence of postoperative complications, thereby…
- Trial name
- NCT07729449
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ordu University
Menkes Disease
NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes Disease
This clinical trial will evaluate the safety, tolerability, dosing, and efficacy of Northera (Droxidopa) in children with Menkes disease aged 7 to 17 years who survived the major neurodegenerative and neurocognitive effects of…
- Trial name
- NCT07398508
- Testing
- Droxidopa Oral Product
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Stephen G. Kaler
Primary Adrenal Insufficiency, Ramadan Fasting
Risks of Ramadan Fasting in Patients With Primary Adrenal Insufficiency Treated With Prednisolone.
In primary adrenal insufficiency (PAI), there is a risk of hypoglycemia and dehydration. These risks seem to be increased during intermittent fasting.
- Conditions
- Primary Adrenal Insufficiency, Ramadan Fasting, Prednisolone, Continuous Glucose Monitoring
- Trial name
- NCT07367425
- Testing
- Ramadan fasting
- Where
- Tunisia
- Volunteers
- 35 people
- Sponsor
- Hopital La Rabta
Low Back Pain
Office Program Effects on Pain, Posture, Muscle Physiology, Stress, Ergonomics, and Quality of Life in LBP Workers
This interventional study aims to evaluate the effectiveness of an office worker's program in reducing low back pain and improving physical and psychosocial outcomes among office employees.
- Trial name
- NCT07250568
- Testing
- Exercise, Education, Advice
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Suci Wahyu Ismiyasa