Clinical trials: LGBTQ, open to volunteers
Body Image
Brief Single-Session Body Neutrality Program for LGBTQ+ Adults in Central Alabama
LGBTQ+ individuals tend to have elevated risks for eating disorders (ED), possibly due to minority stress. For LGBTQ+ individuals living in rural Alabama, they tend to experience high levels of anti-LGBTQ+ structural stigma and…
- Trial name
- NCT07621081
- Testing
- Single session body neutrality program
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Auburn University
Obesity
Optimizing an Online Behavioral Weight Loss Intervention and Novel Culturally Tailored Components for Sexual Minority Women
Obesity disproportionately impacts sexual minority women. Behavioral weight loss programs are the gold standard treatment for mild to moderate obesity.
- Trial name
- NCT05775497
- Testing
- Behavioral weight loss intervention (Online; Rx Weight Loss), Minority stress intervention, Social support intervention
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- The Miriam Hospital
Post-Traumatic Stress Disorder, Chronic, Depressed Mood
An Interrupted Time-Series Pilot Trial of LGBTQ-Affirming Cognitive Processing Therapy for Interpersonal and Developmental Trauma
The researchers are testing a single-group cognitive-behavioral intervention for treating traumatic stress related to interpersonal and developmental trauma in LGBTQ adults.
- Conditions
- Post-Traumatic Stress Disorder, Chronic, Depressed Mood, Depressive and Anxiety Disorders, Anxiety
- Trial name
- NCT07863817
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Minority Stress, Psychological Stress
Effect of Ashwagandha Root Extract on Stress, Anxiety, and Sleep Quality in Adults Experiencing Minority Stress
Sexual and gender minority adults often experience elevated levels of chronic stress due to stigma, discrimination, and social adversity, commonly referred to as minority stress.
- Conditions
- Minority Stress, Psychological Stress, Anxiety
- Trial name
- NCT07441070
- Testing
- Ashwagandha Root Extract
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
HIV/STI Incidence, Communication About Health Information
The Gender Inclusive Sexuality Talks Program
The study is centered on helping parents answer and meet the sexuality-specific questions and needs of transgender, gender diverse, lesbian or bisexual female youth.
- Trial name
- GIST (NCT07825571)
- Testing
- The Gender Inclusive Sexuality Talks Program, GIST Control
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pennsylvania
Minority Stress
Minority Stress Counseling for LGBTQ+ Individuals
Lesbian, gay, bisexual, transgender, and queer+ (LGBTQ+) individuals experience a breadth of mental health disparities. Reducing these disparities is an area of key psychological research.
- Trial name
- MST (NCT06614868)
- Testing
- Acceptance and Commitment Therapy, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
PTSD
A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations
The goal of this clinical trial is see if Cognitive Processing Therapy and STAIR Narrative Therapy work to treat posttraumatic stress disorder (PTSD) among lesbian, gay, bisexual, transgender, queer/questioning, intersex…
- Trial name
- LIFESCAPE (NCT06367764)
- Testing
- Cognitive Processing Therapy, STAIR Narrative Therapy
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Stanford University
Cancer Support, Oncology Patients
FOCUS ON US: Adapting the FOCUS Program for Sexual and Gender Minority (SGM) Cancer Patients and Caregivers
Our aim for this study is to assess the feasibility and acceptability and explore potential outcomes of the adapted FOCUS On Us intervention in a two-arm pilot trial.
- Conditions
- Cancer Support, Oncology Patients, Caregivers
- Trial name
- NCT06800053
- Testing
- FOCUS ON US
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Charles Kamen
Well-Being (Psychological Flourishing), Internalizing Mental Health Symptoms
Micropractices for Unhoused LGBTQ Youth
In the present study, the investigators will conduct a pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of brief, co-designed mindfulness and identity-affirming micropractices…
- Conditions
- Well-Being (Psychological Flourishing), Internalizing Mental Health Symptoms, Substance Abuse
- Trial name
- NCT07566273
- Testing
- Mindfulness and Identity-Based Micropractice, Control Condition Micropractice
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cornell University
LGBTQ
Assessing the Level of Awareness Regarding the Unique Medical Needs of the LGBTQ+ Community Among Emergency Department Physicians, as Well as Their Attitudes Toward Taking Medical Histories, Examining, and Treating Patients From This Community.
Assessing the level of knowledge and awareness regarding the unique medical needs of the LGBTQ+ community among emergency department physicians by distribution of questionnaires to all emergency department physicians (pediatric…
- Trial name
- NCT07770607
- Testing
- Distribution of Questionnaires
- Where
- 3 sites in Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Mental Health Issue, Parent-Child Relations
Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents
The purpose of this study is to assess the efficacy of an LGBTQ-affirmative individual cognitive behavioral psychotherapy (CBT) and LGBTQ-affirmative family therapy (attachment-based family therapy for sexual and gender minority…
- Trial name
- NCT05766592
- Testing
- LGBTQ-affirmative CBT, ABFT-SGM
- Where
- 2 sites in United States, Israel
- Volunteers
- 124 people
- Sponsor
- Yale University
Obesity & Overweight
A Single-arm Pilot Feasibility Trial of Healthy Pride
This is a one-arm pilot trial of a 12-week digitally-delivered asynchronous lifestyle intervention designed for gay men and lesbian women.
- Trial name
- NCT07690592
- Testing
- lifestyle intervention
- Volunteers
- 40 people
- Sponsor
- University of Connecticut
LGBTQ, Racial Disparities
Lakota Family Acceptance Project Pilot RCT
Although research documents the concerning rates of mental and behavioral health problems (e.g., substance use/initiation) among Indigenous LGBTQ2S+ youth, there is very little known about how to prevent these deleterious issues…
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP (NCT07865858)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Heavy Drinking, Mental Health Issue
Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health
The purpose of this 2-arm randomized controlled trial is to assess the efficacy of a 10-session lesbian, gay, bisexual, transgender, and queer (LGBTQ)-affirmative cognitive-behavioral psychotherapy (CBT) delivered via telehealth…
- Trial name
- EQuIP (NCT05509166)
- Testing
- LGBTQ-affirmative Cognitive Behavioral Therapy, LGBTQ-affirmative Treatment-As-Usual
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Yale University
LGBTQ, Racial Disparities
Family Acceptance Project Online (Pilot RCT)
Research shows that sexual and gender minority youth (SGMY) experience high rates of mental health problems and other challenges (e.g., social, academic).
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- FAP-O (NCT06839859)
- Testing
- Family Acceptance Project - Online
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Alcohol Use Disorder (AUD), PTSD
Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building
This is a two-part study to develop and test a brief, virtual therapy program for lesbian, gay, bisexual, transgender, and queer (LGBTQ+) people who have experienced trauma and use alcohol.
- Trial name
- RISE (NCT07217795)
- Testing
- CBT + expressive writing, Wait-List Control
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Rhode Island
Condomless Sex, Sexual Assault
Evaluating a Digital Intervention to Improve Adolescent Condom Use and Communication
The purpose of this study is to test the effectiveness, likability, and implementation potential of PACT, an adapted digital program to teach non-heterosexual adolescent boys about sexual consent and condom negotiation in a…
- Trial name
- NCT06878755
- Testing
- Promoting Assertive Communication among Teens (PACT), Healthy Minds
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Suicide, Self-Injurious Behavior
Youth Empowerment and Safety Intervention
This clinical trial will implement and evaluate the feasibility, acceptability, and initial impact of Peer Support Specialist (PSS) services for public system-involved sexual and gender minority (lesbian, gay, bisexual, queer…
- Trial name
- YES (NCT07214233)
- Testing
- Treatment as Usual, Peer Support Services (PSS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Case Western Reserve University
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine