Clinical trials: LUTS(Lower Urinary Tract Symptoms)
Lower Urinary Tract Symptoms, Hypertension
Effect of Amlodipine Monotherapy or Combined With Terazosin on Lower Urinary Tract Symptoms and Hypertension
The aim of this study was to investigate the efficacy and safety of low dose amlodipine alone, or combined with low dose terazosin in male patients with both lower urinary tract symptoms and hypertension.
- Trial name
- NCT00693199
- Testing
- amlodipine, terazosin, amlodipine plus terazosin
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Anhui Medical University
Benign Prostatic Hypertrophy (BPH), Lower Urinary Track Symptoms
Intradetrusor Onabotulinumtoxin A (Botox) at the Time of Transurethral Resection of the Prostate or Transurethral Waterjet Ablation of the Prostate for Mixed Lower Urinary Tract Symptoms
Patients with longstanding obstructive lower urinary tract symptoms (LUTS) due to benign prostatic hypertrophy (BPH) can also develop symptoms of overactive bladder syndrome (OAB).
- Trial name
- NCT07377929
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Benaroya Research Institute
Patient Engagement, Patient Preference
Increasing Decision Quality for Men With Lower Urinary Tract Symptoms
In this study, the investigators show that by upskilling of primary care physicians (PCPs) in SDM and leveraging on a novel pictorial Visual Analogue Uroflowmetry Score (VAUS), they can enhance older men's recognition of LUTS and…
- Trial name
- NCT04851275
- Testing
- Physicians trained in shared decision making, Physicians were not trained in shared decision making
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SingHealth Polyclinics
BPH, Lower Urinary Tract Symptoms
Transperineal Laser Ablation for Percutaneous Treatment of Benign Prostatic Hyperplasia
This study investigated the effectiveness and safety of SoracteLite ™- Trans-Perineal Laser ablation (TPLA) in the treatment of patients with symptomatic Benign Prostatic Hyperplasia (BPH) at 6 and 12 months follow-up
- Trial name
- NCT04198103
- Testing
- Transperineal Focal Laser Ablation (TPLA)
- Where
- 4 sites in Italy
- Volunteers
- 160 people
- Sponsor
- University of Rome Tor Vergata
Developmental Coordination Disorder, Lower Urinary Tract Symptoms
Impaired Toilet Training, LUTS and Bowel Dysfunction in Children With DCD
This cross-sectional case-control study aimed to determine whether there is a significant difference in the prevalence of impaired toilet training, LUTS, and functional bowel problems among children diagnosed with DCD and…
- Conditions
- Developmental Coordination Disorder, Lower Urinary Tract Symptoms, Bowel Dysfunction
- Trial name
- NCT06311110
- Testing
- Vancouver symptom score for dysfunctional elimination symptoms Questionnaire, Developmental Coordination Disorder Questionnaire, Questionnaire concerning impaired toilettraining and comorbities
- Where
- 2 sites in Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Lower Urinary Tract Symptoms (LUTS) Associated With Benign Prostatic Hyperplasia (BPH)
A Study to Evaluate the Tolerability and Efficacy of Tamsulosin 0.4mg OCAS Formulation in Patients Who Are Unsatisfied With the Treatment of Tamsulosin 0.2mg Conventional Formulation
This is an open-label, single-arm, prospective interventional study to assess the tolerability and efficacy of Harnalidge® OCAS® 0.4 mg in Taiwan patients who are unsatisfied with tamsulosin 0.2 mg for the treatment of lower…
- Trial name
- NCT02180789
- Testing
- Tamsulosin OCAS
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Astellas Pharma Inc
Prostatic Hyperplasia
Study to Characterise the Effect of Tamsulosin on Lower Urinary Tract Symptoms (LUTS) and Detrusor Motor Activity in Patients Affected by Benign Prostatic Hyperplasia (BPH) and Storage Urinary Symptoms
Study to evaluate the efficacy of tamsulosin on storage symptoms and detrusor motor activity in patients with LUTS suggestive of BPH and relevant storage symptoms
- Trial name
- NCT02245490
- Testing
- Tamsulosin HCl controlled release capsules
- Volunteers
- 153 people
- Sponsor
- Boehringer Ingelheim
Benign Prostatic Hyperplasia, Prostate Cancer
Effects of Alpha Blockers on Prostate-specific Antigen (PSA) Change in Men With Lower Urinary Tract Symptoms (LUTS)
The correlation between the change of serum prostate-specific antigen (PSA) or PSA velocity (PSAV) and severity of lower urinary tract symptoms (LUTS) has been poorly understood.
- Trial name
- NCT01250483
- Testing
- PSA measurement, uroflowmetry, IPSS, transrectal ultrasonography
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Seoul National University Hospital
Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Effect of 12 Weeks Treatment With Tadalafil vs Placebo on Lower Urinary Tract Symptoms
At present time several preclinical and clinical study have demonstrated the safety and efficacy of PDE5 (phosphodiesterase type 5)-inhibitors for LUTS/BPH (lower urinary tract symptoms/benign prostatic hyperplasia) patients with…
- Trial name
- NCT02252367
- Testing
- Tadalafil
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Florence
Lower Urinary Tract Symptoms, Overactive Bladder Syndrome
Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome
The goal of this clinical trial is to test the effect of a supplement called MitoQ (mitoquinol mesylate) on bladder symptoms such as urgency and frequency in women 50 years and older who have the metabolic syndrome.
- Trial name
- Mito-LUTS (NCT06351683)
- Testing
- MitoQ (mitoquinol mesylate)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Iman Al-Naggar, PhD
Prostatic Hyperplasia
The Impact of Alna® Ocas® on Nocturia in Patients With Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia (LUTS/BPH)
Study to assess efficacy, tolerability and safety parameters of a three month ALNA®OCAS® -treatment with special respect to nocturia
- Trial name
- NCT02245542
- Testing
- ALNA®OCAS®
- Volunteers
- 5,775 people
- Sponsor
- Boehringer Ingelheim
Prostate Cancer, Lower Urinary Tract Symptoms (LUTS)
Concomitant Trans-Perineal Prostate Biopsy and Ablation (Bioblation) for Prostate Cancer
This prospective study aims to validate the clinical outcomes of performing a concomitant trans-perineal prostate biopsy and laser ablation (termed "Bioblation") during a single session.
- Conditions
- Prostate Cancer, Lower Urinary Tract Symptoms (LUTS), Benign Prostatic Hyperplasia
- Trial name
- Bioblation (NCT07526675)
- Testing
- Bioblation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Prostatic Neoplasms, Prostate Disease
Single Dose Versus Double Dose Tamsulosin in Management of Moderate and Severe LUTS Due to BPH
Single dose versus double dose tamsulosin in Management of Moderate and severe lower urinary tract symptoms due to benign prostatic hyperplasia
- Conditions
- Prostatic Neoplasms, Prostate Disease, Prostate Obstruction, Prostate Hypertrophy
- Trial name
- NCT05834270
- Testing
- Single dose tamsulosin 0.4mg, Double dose tamsulosin 0.4mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
BPH Global Registry
Benign prostatic hyperplasia (BPH) is one of the most common performed surgical procedures in urology. Over the past few decades there have been an increasing development of newer surgical treatment options.
- Trial name
- NCT05543200
- Where
- 30 sites in United States, Canada and 19 more
- Volunteers
- 7,500 people
- Sponsor
- Société Internationale d'Urologie
Benign Prostatic Hyperplasia
Interest of a Systematic Assessment of the Treatment of LUTS in the Management of BPH
The high level of unsatisfactory outcome observed in patients treated for LUTS associated with BPH with respect to the different existing therapeutic options strongly emphasizes the need for treatment optimisation in daily…
- Trial name
- UROEVAL (NCT03179670)
- Where
- France
- Volunteers
- 625 people
- Sponsor
- RECORDATI GROUP
Benign Prostatic Hyperplasia (BPH)
Laser Ablation a Salvage Treatment for Obstructive Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a common condition affecting aging men, often leading to lower urinary tract symptoms (LUTS).
- Trial name
- ECHOLASER (NCT07016620)
- Testing
- Transperineal Laser Ablation (TPLA)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Lower Urinary Tract Symptoms (LUTS)
RCT on Running Water Sound During Urodynamic
This study aims to see if listening to recorded running water sounds during a bladder function test (urodynamic study) helps patients feel calmer and makes it easier for them to empty their bladder during the test.
- Trial name
- NCT07451548
- Testing
- Auditory intervention with running water sound
- Where
- 2 sites in Hong Kong
- Volunteers
- 240 people
- Sponsor
- Princess Margaret Hospital, Hong Kong
Cerebral Palsy, Lower Urinary Tract Symptoms
Applicability of Uroflowmetry in Children with Cerebral Palsy
Until now, the use of invasive urodynamics with use of catheters is still the gold standard for lower urinary tract evaluation in subjects with CP.
- Trial name
- NCT05017415
- Testing
- uroflow measurement, Bladder ultrasound
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University Hospital, Ghent
Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
Anterior Bridge-Preserving Versus Conventional Early Apical Release During Holmium Laser Enucleation of the Prostate
Holmium laser enucleation of the prostate (HoLEP) is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
- Trial name
- ABPS-EAR-HOLEP (NCT07892599)
- Testing
- Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
- Volunteers
- 230 people
- Sponsor
- Ahmed Ebrahim Zahran
Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptoms (LUTS)
Trial of the Safety and Efficacy of Ozarelix in Participants With Benign Prostatic Hyperplasia (BPH)
This is a multi-center, randomized, double-blind, placebo-controlled study to evaluate the efficacy of ozarelix compared to placebo in the treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia…
- Trial name
- NCT00743184
- Testing
- ozarelix
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Spectrum Pharmaceuticals, Inc