Clinical trials: Label Comprehension
Hypertension
Attitudes and Understanding of Sodium Claims on Food Labels
Sodium-related claims on food labels should help people find lower sodium food choices; however consumer attitudes and understanding of such claims are unknown.
- Trial name
- NCT01764724
- Testing
- Mock package questionnaire
- Where
- Canada
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Adults
A Study to Understand How the Body Processes [14C]PF-07104091 in Healthy Participants
The purpose of this study is to learn how the body processes the study medicine PF-07104091. The study is seeking participants who are: Healthy male aged 18 to 65 years of age Participants in the study will receive 14C-labeled…
- Trial name
- NCT07127770
- Testing
- PF-07104091
- Where
- Netherlands
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Pfizer
To Understand the Characteristics of Digital Mental Health Intervention Users as They Relate to Mental Health Outcomes
How Phenotypical Characteristics of Woebot Users Are Related to Clinical Outcomes
The goal of this observational study is to understand the characteristics of Woebot users as they relate to clinical outcomes. The objectives it aims to address are: 1.
- Trial name
- NCT05672745
- Testing
- WB-LIFE
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Woebot Health
Meningitis, Septicemia
Understanding the Immune Response to Meningitis Vaccines
The purpose of the study is to evaluate and compare the immune response to two vaccines against 4 related bacteria: meningococcal serogroups A, C, W-135 and Y.
- Trial name
- NCT00901940
- Testing
- Meningococcal (Groups A, C, Y and W-135) Conjugate, Meningococcal polysaccharide A, C, Y and W135 and Menveo
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Prescription Medication Understanding
Enhanced Prescription Drug Label to Improve Patient Understanding and Use
The overall objective of this study is to test the efficacy of an evidence-based, enhanced Rx container label design to improve patients' understanding of instructions for use.
- Trial name
- NCT00973180
- Testing
- Enhanced Label
- Where
- United States
- Volunteers
- 850 people
- Sponsor
- Northwestern University
Binge Drinking
An Open Label Trial of Bupropion and Naltrexone for Binge Drinking
This is an open-label Phase IIa pilot study of the tolerability and effects on binge drinking of bupropion and naltrexone for binge drinkers.
- Trial name
- NCT02842073
- Testing
- Naltrexone, Bupropion
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of North Carolina, Chapel Hill
Healthy
A Study To Understand How The Body Reacts To A Low Dose Of PF-06427878 When Given In A Vein To Healthy, Adult, Males
To determine how the body reacts to a low dose of PF-06427878 when given in a vein over 30 minutes to healthy, adult, males.
- Trial name
- NCT02237742
- Testing
- PF-06427878
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pfizer
Solid Tumours
A Study in Healthy Male Subjects to Understand How Savolitinib Behaves Inside the Body (Pharmacokinetics) When Administered Alone and in Combination With Famotidine
This will be an open-label, randomised, 2 part (Part A and Part B), 2 treatment (savolitinib alone or in combination with famotidine), crossover study in healthy, non Japanese, male subjects, performed at a single study centre.
- Trial name
- NCT04179071
- Testing
- Savolitinib, Famotidine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Meningitis, Meningococcal Disease
Understanding the Immune Response to Two Different Meningitis Vaccines
The bacterium (germ) Neisseria meningitidis causes meningitis and blood poisoning. N meningitidis is classified into different serogroups (types), based on its outer polysaccharide (carbohydrate) capsule.
- Conditions
- Meningitis, Meningococcal Disease, Septicaemia
- Trial name
- NCT01593514
- Testing
- MenACWY-CRM conjugate vaccine (Menveo, Novartis), MenACWY-PS polysaccharide vaccine, ( ACWYVax, GSK) and MenACWY-CRM conjugate vaccine (Menveo, Novartis), 1/5th dose MenACWY-PS polysaccharide vaccine, ( ACWYVax, GSK) and MenACWY-CRM conjugate vaccine (Menveo, Novartis)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Healthy
A Study to Understand the Effect of a Study Medicine Called ARV-471 on Dabigatran Etexilate in Healthy Adults
The purpose of this study is to understand if ARV-471 affects how a medicine called, dabigatran etexilate, gets absorbed or processed into the body in healthy adults.
- Trial name
- NCT05673889
- Testing
- ARV-471, Dabigatran etexilate
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Muscle Atrophy, Disuse Atrophy
Effect of Knee Position on Muscle Loss During Leg Immobilization
This study looks at what happens to leg muscles when the knee is kept straight or bent during five days of wearing a brace. We want to find out if keeping the knee bent (so the thigh muscle is stretched) helps prevent muscle loss…
- Conditions
- Muscle Atrophy, Disuse Atrophy, Immobilization
- Trial name
- NCT07690150
- Testing
- Knee immobilization brace (0°) for 5 days, Knee immobilization brace (60°) for 5 days
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Contraception, Menopause
Study Conducted to Further Understand the Elimination Pathways, Metabolite Profile and PK Profile of 14C-estetrol
This study is being conducted to further understand the elimination pathways, metabolite profile and pharmacokinetic (PK) profile of carbon 14 labelled estetrol ([14C] estetrol).
- Trial name
- NCT02720224
- Testing
- Estetrol
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Estetra
Acetaminophen Overdose, Pain
Investigation of Efficacy of Improved Acetaminophen Labeling
The purpose of this study is to evaluate, through brief, one-on-one cognitive interviews, the efficacy of 'enhanced' acetaminophen messages and icons in improving consumer understanding and use of prescription (Rx) and…
- Trial name
- NCT01592448
- Testing
- Active Ingredient Icon
- Where
- 4 sites in United States
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Healthy Male Volunteers
A Study to Understand How the Study Medicine (PF-07976016) is Processed and Eliminated in Healthy Men
The purpose of this study is to learn about how much the study medicine PF-07976016 will be taken up and processed by healthy male participants. The total number of weeks of the study is up to approximately 12 weeks.
- Trial name
- NCT07015918
- Testing
- [14C] PF-07976016, PF-07976016
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pfizer
Solid Tumors
A Study in Healthy Male Subjects to Understand How Savolitinib When Taken With Midazolam Behaves Inside the Body
This study will be an open label, 2 period, fixed sequence study in healthy male subjects, performed at a single study center in the Unites States of America.
- Trial name
- NCT04187456
- Testing
- Savolitinib, Midazolam
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Sjogren Syndrome
Biopsy Based Study to Understand Mechanism of Action of Ianalumab in Salivary Glands and Explore Relationships With Clinical Assessments.
This study aims at elucidating the mechanism of action of ianalumab in salivary glands and explore relationships with clinical assessments
- Trial name
- NCT05124925
- Testing
- Ianalumab
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Novartis Pharmaceuticals
Acute Pain
Does the Understanding of Placebo Mechanisms Compensate for the Loss of Efficacy Associated With Open Label Placebo
The investigators are investigating whether, when given detailed information about underlying placebo mechanisms and pain, subjects will have a response similar to that of those subjected to a procedure in which they receive a…
- Trial name
- PLACETHIC (NCT03934138)
- Testing
- Informative movie on hand washing
- Where
- 2 sites in France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Laboratoire TIMC-IMAG
Healthy Participants
A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men
The purpose of this clinical trial is to learn about how much PF-07081532 will be taken up and processed by healthy male participants. The study consists of two parts, called study periods.
- Trial name
- NCT05652647
- Testing
- Oral [14C]PF-07081532, Oral PF-07081532 and IV [14C]PF-07081532
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pfizer
Consumer Research, General Population
Attidutes and Understanding of Oat Fibre Claims on Food Labels
Oat fibre consumption has been shown to lower blood cholesterol, which is advantageous for heart health. Oat and fibre claims on food labels should help people find heart healthy food choices; however consumer attitudes and…
- Trial name
- NCT01932827
- Testing
- Mock Package Questionnaire
- Where
- Canada
- Volunteers
- 1,002 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Circumference Reduction
Study of Over-The-Counter Use of Low Level Laser Light Therapy for Body Contouring of the Waist, Hips and Thighs
The purpose of this study is to test the ability of the lay end user to understand the information contained in the User's Guide; to correctly identify patients who are suitably qualified to receive treatment; and to correctly…
- Trial name
- NCT02167867
- Testing
- Lay End Users, Treatment Subject Group
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation