Clinical trials: Labor Complications
Premature Rupture of Membrane
Comparison of Two Antibiotic Prophylactic Protocols in Preterm Premature Rupture of the Membranes
The objective of the study is to compare a new antibiotic protocol with the current prophylactic treatment in routine use and to evaluate obstetric and neonatal outcome: preterm labor, chorioamnionitis and early onset sepsis
- Trial name
- NCT02819570
- Testing
- I.V cefuroxime 750 mg*3/d for 2 days, I.V ampicillin 2 gram x4/d for 2 days, P.O cefuroxime 500 mgx2/d for 5 days
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Western Galilee Hospital-Nahariya
Gastroesophageal Reflux, Apnea
Study of Erythromycin in GER-Associated Apnea of the Newborn
To evaluate the relationship of reflux and apnea and to determine whether the administration of erythromycin improves the incidence of GER and GER-associated apnea, bradycardic and/or desaturation events in a prospective…
- Conditions
- Gastroesophageal Reflux, Apnea, Bradycardia
- Trial name
- SEGAN (NCT01825473)
- Testing
- Erythromycin, Multi-channel intra-luminal impedance (MII) pH monitoring
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Labor Dystocia
Anticholinergics for Cervical Edema in Labor
The purpose of this study is to is to determine the clinical effectiveness of a single dose of intravenous (IV) medication for the prevention of labor arrest and cesarean delivery in primiparous women undergoing trial of labor.
- Trial name
- ACCEL (NCT06702670)
- Testing
- Treatment with Diphenhydramine, Usual Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
Preterm Birth, Child Development
Omega Tots Long Term Follow-up
This is a continuation study to the Omega Tots trial (NCT01576783). The purpose of this study is to follow-up with participants of the original study to determine the long-term effect a daily fatty acid dietary supplement taken…
- Trial name
- NCT05191823
- Testing
- Docosahexaenoic Acid + Arachidonic Acid (DHA+AA)
- Where
- United States
- Volunteers
- 377 people
- Sponsor
- Sarah Keim
Hirsutism, Type 2 Diabetes
Prospective Study of Patients With Hirsutism
Hirsutism is the presence of terminal hairs in a male-like pattern in females, due to elevated male hormone levels. Females with hirsutism are often overweight and have metabolism disturbances as insulin resistance and impaired…
- Conditions
- Hirsutism, Type 2 Diabetes, Polycystic Ovary Syndrome
- Trial name
- NCT00145288
- Where
- Denmark
- Volunteers
- 340 people
- Sponsor
- Odense University Hospital
Preterm Birth
Hammock Positioning's Influence on the Electromyographic Activity in the Flexor Muscles in Newborn Preterm
The individual who is born premature, in addition to a CNS still in accelerated training suffers early loss of intrauterine restraint, conditions that promote hypotonia characteristic of premature birth.
- Trial name
- NCT02621996
- Testing
- hammock, containment nest
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Fetal Membranes, Premature Rupture, Ultrasonography
The Cervical Cap in the Diagnosis of Rupture of Membranes in the Second Trimester
Early preterm premature rupture of membranes (PPROM) complicates 0.7% of pregnancies. When PPROM occurs before the 24th week,the risk of fetal and neonatal death is 70%.
- Trial name
- NCT01063686
- Testing
- insemination cervical cap
- Where
- Israel
- Sponsor
- Rabin Medical Center
Neonatal Respiratory Distress Syndrome
Impact of Neurophysiological Facilitation of Respiration in Preterm Neonates
Background: Respiratory distress syndrome (RDS) or Neonatal respiratory distress syndrome (NRDS) is characterized by pulmonary insufficiency, in preterm neonates and is the major cause of death in preterm.
- Trial name
- NCT04019886
- Testing
- Neurophysiological Facilitation of Respiration
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Asir John Samuel
Preterm Infant
Sustained Lung Inflation in Preterm Infants
This is a randomized controlled study to investigate the effect of application of sustained lung inflation (SLI) at birth on the respiratory outcome of preterm infants with respiratory distress syndrome.
- Trial name
- NCT03518762
- Testing
- Sustained lung inflation (SLI), Continuous positive airway pressure (CPAP)
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Kasr El Aini Hospital
Preterm Birth
COIN: A Pilot Study of Cash Transfers to Improve Outcomes in Low-Income Preterm Neonates and Their Families
The investigators are conducting a pilot randomized controlled trial of unconditional cash transfers among Medicaid-eligible birthing parents of preterm infants in a single neonatal intensive care unit (NICU) in Pennsylvania.
- Trial name
- NCT05930327
- Testing
- Unconditional Cash Transfer (High-Value), Unconditional Cash Transfer (Low-Value)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Children's Hospital of Philadelphia
Cesarean Section Complications
Comparison of N&H Sandwich Technique and Cesarean Hysterectomy in Management of Placenta Accreta Spectrum
The placenta accreta spectrum (PAS)is one of the most common reasons for cesarean hysterectomy Which associated with high rates of severe maternal morbidity (40%-50%), with reported mortality rates up to 7%.
- Trial name
- NCT03701386
- Testing
- cesarean hysterectomy, N&H sandwich technique
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Aswan University Hospital
Shoulder Dystocia
TelesDystocia: Tele-Support vs. Cognitive Aid in Simulated Shoulder Dystocia
Shoulder dystocia is an unpredictable, time-critical obstetric emergency requiring immediate recognition and rapid execution of established maneuvers.
- Trial name
- TelesDystocia (NCT07772102)
- Testing
- Remote Tele-Support, Cognitive Aid
- Where
- Austria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Post Partum Haemorrhage
Investigating the Efficacy of Tranexamic Acid as a Prophylactic Agent in Reducing Postpartum Hemorrhage Among Patients Undergoing Cesarean Section in SQUH
Investigating the efficacy of tranexamic acid (TXA) as a prophylactic agent in reducing postpartum haemorrhage (PPH) among patients undergoing cesarean section (CS) in SQUH: a prospective randomized controlled trial.
- Trial name
- NCT07474077
- Testing
- tranexamic acid (1 g diluted in 100 mL of 0.9% saline, Normal (0.9%) saline
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Sultan Qaboos University
Obstetric Labor, Labor Onset
The Prognostic Value of Cervical Elastography for Identifying Patients at Risk for Preterm Delivery
The hypothesis tested is that the physical changes associated with cervical ripening result in a detectable decrease in rigidity.
- Conditions
- Obstetric Labor, Labor Onset, Obstetric Labor, Premature
- Trial name
- ElastoMAP (NCT02021539)
- Testing
- Cervical ultrasound +elastography 1, Vaginal fibronectin measurement, Tocolytic treatment for 2 hours
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Placenta Previa
Characteristics, Complications and Perinatal Outcomes in Placenta Previa Women
This study aim to investigate the characteristics, complications and perinatal outcomes in pregnant women with placenta previa.
- Trial name
- NCT03774667
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Maternal and Child Health Hospital of Foshan
Psychiatric Nursing, Depression Disorder
The Effect of Psychodrama-Based Group Work
Aims This study examined the effect of psychodrama-based group work on postpartum women's tendencies toward depression and forgiveness.
- Conditions
- Psychiatric Nursing, Depression Disorder, Forgiveness, Puerperal Depression
- Trial name
- NCT07305571
- Testing
- psychodrama-based group intervention, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Ömer USLU
Placental Malaria Infection, HIV Infections
Intermittent Preventive Treatment of Malaria in HIV-Seropositive Pregnant Women in Zambia
Prevention of malaria in pregnancy is critical given the high incidence of malaria in Zambia and its serious impact on both maternal and infant survival.
- Conditions
- Placental Malaria Infection, HIV Infections, Stillbirth, Prematurity
- Trial name
- NCT00270530
- Testing
- Sulfadoxine-pyrimethamine (Fansidar)
- Where
- Zambia
- Volunteers
- 454 people
- Sponsor
- Center for International Health and Development
Pregnancy Related, Hemorrhage
The Effect of Fluids on Aortic VTI During C-section
Pregnancy is associated with a myriad of physiologic changes, including expansion of blood volume, decrease in oncotic pressure, and increased cardiac output. The obstetric population is associated with intrapartum hemorrhage.
- Conditions
- Pregnancy Related, Hemorrhage, Fluid Overload, Labor Complication
- Trial name
- NCT04330742
- Testing
- lactated ringers
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Premature Birth
Acoustic Analysis of the First Babies Crying in Delivery Room and Adaptation to Extra Uterine Life
Interpreting the cry of new-borns is a real challenge not only for perinatal professionals but also for parents, who are confronted daily with those sounds.
- Trial name
- FIRSTCRY (NCT04849234)
- Testing
- newborn cries
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Premature Birth
Study on the Development of Neonatal Cerebral Blood Flow Based on Ultrafast Ultrasound Doppler Imaging
Recently, with the development of perinatal medicine in China, the establishment of neonatal intensive care unit (NICU) and the improvement of respiratory support technology, the survival rate of preterm and term neonates has…
- Trial name
- NCT05761548
- Testing
- ultrafast ultrasound power Doppler imaging
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
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