Clinical trials: Labor Complications
Postpartum Hemorrhage \(PPH\), Postpartum Hemorrhage \(Primary\)
Safety and Effectiveness of the Alma System in Treating Primary Postpartum Hemorrhage
Postpartum Hemorrhage (PPH) is an obstetric emergency that can occur up to 24 hours after vaginal birth or cesarean section. In most cases, the uncontrolled bleeding is due to a lack of sufficient contraction of the uterus…
- Conditions
- Postpartum Hemorrhage \(PPH\), Postpartum Hemorrhage \(Primary\), PPH
- Trial name
- NCT06166771
- Testing
- Alma system
- Where
- Kenya
- Volunteers
- 10 people
- Sponsor
- ResQ Medical Ltd
Infant, Premature
The Effects of Family Centered Intervention Program on Preterm Infants
Infant born preterm have an increased risk of adverse long-term developmental outcomes.The risk associated with preterm birth increase as gestational age decreases, and vulnerability remains in moderate and early preterm (<34…
- Trial name
- NCT03146351
- Testing
- Family based early intervention program (NDT-Bobath based)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Gazi University
Postpartum Hemorrhage (Primary)
Carbetocin Versus Oxytocin for the Prevention of Postpartum Hemorrhage in Emergency Caesarean Delivery
Postpartum haemorrhage keeps to be the leading cause of maternal mortality in middle and low-income countries, including Iraq. Much advancement had been made in the field of treatment for postpartum haemorrhage but no much…
- Trial name
- NCT03755531
- Testing
- Carbetocin, Oxytocin
- Where
- Iraq
- Volunteers
- 300 people
- Sponsor
- Al-Kindy College of Medicine
Preterm Birth
Cervical Cerclage for Preventing Spontaneous Preterm Birth in Singleton Pregnancies Without Prior Spontaneous Preterm Birth and With Short Transvaginal Ultrasound Cervical Length
Spontaneous preterm birth (SPTB) remains the number one cause of perinatal mortality in many countries, including the United States.
- Trial name
- NCT02746900
- Testing
- Cervical cerclage
- Where
- Italy
- Volunteers
- 587 people
- Sponsor
- Federico II University
Premature Birth
Delayed Umbilical Cord Clamping in Infants Less Than 32 Weeks
The overall objective of the present study is to examine the effects of delayed umbilical cord clamping in preterm infants on neonatal outcomes using a prospective randomized controlled trial comparing immediate cord clamping…
- Trial name
- DUC (NCT00562536)
- Testing
- Umbilical cord clamping
- Where
- Canada
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
PreTerm Birth
Physical Examination-Indicated Pessary
Cervical insufficiency, previously referred to as cervical incompetence, has classically been defined as painless dilation of the cervix in the absence of contractions or bleeding in the second trimester resulting in recurrent…
- Trial name
- NCT02967445
- Testing
- Arabin Pessary, Cervical cerclage
- Where
- Italy
- Sponsor
- Federico II University
Infant, Premature
Prematurity-Related Ventilatory Control: Role in Respiratory Outcomes
The objective of this common multicenter protocol is to test the hypothesis that algorithmic tools using clinical Neonatal Intensive Care Unit (NICU) cardiorespiratory monitoring data can detect ventilatory control instability…
- Trial name
- Pre-Vent (NCT03174301)
- Where
- United States
- Volunteers
- 739 people
- Sponsor
- University of Virginia
Apnoea, Prematurity
Automated Apnoea Detection in Preterms on Non-invasive Ventilation
The aim of this study is to monitor the frequency of apnoeas (pauses in breathing) on various methods of non-invasive respiratory support that are detected by an automated machine-learning (ML) model based on diaphragmatic…
- Trial name
- NCT07794007
- Testing
- Diaphragmatic electromyography
- Volunteers
- 30 people
- Sponsor
- King's College Hospital NHS Trust
Newborn Respiratory Distress, Preterm Infant
Short Term Effects of Synchronized vs. Non-synchronized NIPPV in Preterm Infants.
Comparing the cardio-respiratory adaptation and differences to non invasive ventilation techniques, nasal intermittent positive pressure ventilation (NIPPV) non synchronized vs synchronized (SNIPPV) in preterm newborns…
- Trial name
- SyncNIV (NCT03289936)
- Testing
- NIPPV, SNIPPV
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
PROM (Pregnancy), Induced; Birth
Effects of Acupuncture in Spontaneous Rapture of Membranes: Applicability and Effectiveness
The aim of the study is to investigate the effects of acupuncture in women presenting with spontaneous rapture of membranes (PROM) at term and negative swab for Streptococcus Agalactie to promote a spontaneous onset of labour and…
- Conditions
- PROM (Pregnancy), Induced; Birth, Acupuncture, Labour
- Trial name
- NCT06623175
- Testing
- Acupuncture needles
- Where
- Italy
- Volunteers
- 131 people
- Sponsor
- Prof. Fabio Facchinetti
Hypothermia
Clinical Performance of the Embrace Isothermal Mattress
The purpose of this pilot study is to evaluate the performance of a new warming technology (Embrace Isothermal Mattress) during the thermal weaning of premature infants from incubators to open cribs.
- Trial name
- KBW (NCT01425086)
- Testing
- Embrace, PCM, warming blanket
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Stanford University
Breast Milk Fortifier Supplements, Premature
The Effect of Time to Start Breast Milk Fortifiers on Neonatal Outcomes in Very Low Birth Weight Premature Infants.
In the study, very low birth weight babies born in our hospital will be randomized in the closed envelope method, and breast milk fortifier will be started when 50 ml/kg/day breastfeeding volume is reached in one group, and…
- Trial name
- NCT05251441
- Testing
- Breast Milk Fortifier supplements
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ankara City Hospital Bilkent
Sepsis, Prematurity
An Open Label Study to Describe the Pharmacokinetics of Cefazolin in Preterm Neonates
This is a phase I open label multi-dose study to investigative the pharmacokinetics and safety of cefazolin in infants <121 days of age and < 28 weeks gestation with suspected sepsis.
- Trial name
- NCT00850122
- Testing
- cefazolin
- Where
- Brazil
- Volunteers
- 9 people
- Sponsor
- Phillip Brian Smith
Patent Ductus Arteriosus After Premature Birth
Indomethacin PK-PD in Extremely Preterm Neonates
This is a phase II open-label study evaluating the pharmacokinetics and pharmacodynamics of targeted early use of indomethacin for PDA treatment in preterm neonates <27 weeks' gestational age.
- Trial name
- INDO (NCT04025177)
- Testing
- Indomethacin Injection
- Where
- 2 sites in Canada
- Sponsor
- University of Manitoba
Infant, Newborn, Infant, Low Birth Weight
Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2)
This pilot study is a randomized, placebo-controlled, clinical trial to measure changes in blood and urine levels of inositol in premature infants at high risk for retinopathy of prematurity (ROP) following repeated doses of…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- INS-2 (NCT01030575)
- Testing
- Inositol lower volume, Inositol mid-level volume, Inositol high volume
- Where
- 17 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Premature Birth
Effects of Baby Massage on Parenting Stress and Attachment in Premature
This study is an experimental randomized controlled clinical trial. To explore the effect of infant massage on parental pressure and parent-child attachment of premature infants.
- Trial name
- NCT04255797
- Testing
- baby massage
- Where
- Taiwan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
PreTerm Birth
Supporting Mothers of Preterm Infants
Preterm birth is the leading contributor to mortality among children younger than 5 years. One effective and inexpensive intervention is providing skin-to-skin care (STSC) whereby the mother of a preterm baby provides…
- Trial name
- NCT03013660
- Testing
- Limited Financial Support
- Where
- 2 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Abruptio Placentae
Plasma Concentration of Biological Markers in Placental Abruption
This will be a prospective study conducted on women with a suspected/confirmed diagnosis of placental abruption. Maternal blood samples will be taken at various points during the peripartum period.
- Trial name
- NCT03782168
- Testing
- There is no other intervention, only clinical treatment.
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Arkansas
Premature Newborn
Influence of the Use of Hearing Protection in the Salivary Cortisol Level and in the Sleep of Premature Infants
The aim of this study was to investigate the influence of the use of headphones in salivary cortisol levels in newborns (NB) during periods of nap aimed at noise reduction, brightness and handling NB, measure the concentrations…
- Trial name
- NCT02781168
- Testing
- use of earmuffs
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Pregnancy, Eclampsia
A Cluster-Randomized Trial of Ultrasound Use to Improve Pregnancy Outcomes in Low Income Country Settings
In many low-income countries, the use of ultrasound by medical officers and non-physician health care staff (e.g., midwives) for antenatal identification of high risk pregnancies is a new intervention requiring authoritative…
- Conditions
- Pregnancy, Eclampsia, Placenta Previa, Stillbirth
- Trial name
- NCT01990625
- Testing
- Antenatal Ultrasound Scan
- Where
- 5 sites in Guatemala, Kenya and 3 more
- Volunteers
- 45,038 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.