Clinical trials: Labor Delivery
Chorioamnionitis
Selective Use of Antibiotics in Neonates Born to Mothers With Suspected Chorioamnionitis
Retrospective Chart Review to determine the selective use of antibiotics in neonates born to mothers with suspected chorioamnionitis
- Trial name
- Chorio (NCT03576560)
- Testing
- Retrospective Chart Review
- Where
- United States
- Volunteers
- 768 people
- Sponsor
- Pediatrix
Mood, Stress, Psychological
Stress Management for Cancer Patients: How Well Does it Work? (C2H-D)
Psychological interventions for cancer patients have been tested and found to reduce stress and improve quality of life. These interventions have been tested at academic medical centers but have not been available for use by…
- Trial name
- C2H-D (NCT02070250)
- Testing
- From Cancer to Health (C2H-D)
- Where
- 15 sites in United States
- Volunteers
- 158 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Respiratory Distress Syndrome, Preterm Birth
Surfactant for Neonatal Respiratory Distress Syndrome(NRDS) and Neonatal Acute Respiratory Distress Syndrome(NARDS)
In preterm infants with neonatal respiratory distress syndrome (NRDS), exogenous pulmonary surfactant(PS) replacement therapy is one of the most important therapeutic breakthrough to reduce neonatal mortality.
- Conditions
- Respiratory Distress Syndrome, Preterm Birth, Acute Respiratory Distress Syndrome, Surfactant Dysfunction
- Trial name
- NCT04777760
- Testing
- one dose of surfactant replacement, two and more doses of surfactant replacement
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Post Partum Hemorrhage
Use of TXA to Prevent Postpartum Hemorrhage
Postpartum hemorrhage (PPH) occurs in up to one in ten deliveries worldwide and is the leading cause of maternal morbidity and mortality.
- Trial name
- TAPPH-1 (NCT03069859)
- Testing
- TXA (1g)
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Sunnybrook Health Sciences Centre
Obstetrical Complications, Hemorrhage
Tranexamic Acid for the Prevention of Obstetrical Hemorrhage After Cesarean
A randomized placebo-controlled trial of 11,000 women to assess whether tranexamic acid as prophylaxis lowers the risk of postpartum hemorrhage in women undergoing a cesarean delivery.
- Conditions
- Obstetrical Complications, Hemorrhage, Labor and Delivery
- Trial name
- TXA (NCT03364491)
- Testing
- Tranexamic Acid
- Where
- 12 sites in United States
- Volunteers
- 11,000 people
- Sponsor
- The George Washington University Biostatistics Center
Premature Infants, Patent Ductus Arteriosus
Ibuprofen and Renal Function in Premature Infants
Purpose of the study: 1. To evaluate renal function maturation within the first month of life in very premature infants. 2. To determine whether a treatment with Ibuprofen for patent ductus arteriosus would alter renal function…
- Trial name
- NCT00217191
- Testing
- Ibuprofen
- Where
- 3 sites in France
- Volunteers
- 120 people
- Sponsor
- Maternite Regionale Universitaire
Premature Infants
The Effect of Using Clinical Guidelines on Kangaroo Care on Newborn and Maternal Outcomes
The aim of this study was to determine the effect of the use of clinical guidelines in kangaroo care (KB) practice on neonatal and maternal outcomes in premature infants.
- Trial name
- NCT05807191
- Testing
- Kangaroo care based on kangaroo care guide
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Preterm Birth, Parent-Child Relations
Biological Underpinnings of Socio-emotional Regulation in Preterm Infants and Healthy Controls
Preterm infants (PT) often need to spend their first weeks of life in the Neonatal Intensive Care Unit (NICU) where they are exposed to several adverse conditions.
- Conditions
- Preterm Birth, Parent-Child Relations, Epigenetics
- Trial name
- NCT05253924
- Testing
- DNA methylation of target genes, EEG acquisition
- Where
- Italy
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Respiratory Syncytial Virus Hospitalizations
An Observational Study of Respiratory Syncytial Virus (RSV) Hospitalizations in Preterm Infants
Purpose of this study is to evaluate clinical, humanistic and health economic burden of Respiratory Syncytial Virus (RSV) in infants born 29 to 35 Weeks Gestational Age (wGA) hospitalized for RSV at up to 12 months of age.
- Trial name
- SENTINEL1 (NCT02273882)
- Where
- 44 sites in United States
- Volunteers
- 497 people
- Sponsor
- AstraZeneca
Pulmonary Disease, Chronic Obstructive
A Study to Determine the Effect of Tiotropium + Olodaterol Fixed Dose Combination on Exercise Endurance Time During Constant Work Rate Cycle Ergometry Test in COPD
The primary objective of this study is to compare the effects of orally inhaled tiotropium + olodaterol fixed dose combination (2.5/5 µg; 5/5 µg) with placebo on exercise tolerance after 12 weeks of treatment in patients with…
- Trial name
- NCT01525615
- Testing
- Respimat inhaler, tiotropium+olodaterol (low dose), tiotropium + olodaterol (high dose)
- Where
- 60 sites in United States, Argentina and 8 more
- Volunteers
- 404 people
- Sponsor
- Boehringer Ingelheim
Premature Birth
Delayed Umbilical Cord Clamping in Infants Less Than 32 Weeks
The overall objective of the present study is to examine the effects of delayed umbilical cord clamping in preterm infants on neonatal outcomes using a prospective randomized controlled trial comparing immediate cord clamping…
- Trial name
- DUC (NCT00562536)
- Testing
- Umbilical cord clamping
- Where
- Canada
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Infant, Premature
Effect of Baby Massage on Oral Motor Skills of Premature Babies
This experimental research was conducted in a single-blind, block randomized controlled design type. The primary purpose of the study is to examine the effect of premature baby massage on oral motor coordination skills.
- Trial name
- NCT06308471
- Testing
- Baby massage was applied to the intervention group (n=20) of the study, Oral stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Weight Gain Preterm
Strategy to Minimize In-hospital Malnutrition in Premature Babies
Adequate nutrition is important for preventing malnutrition in the postnatal period and thus optimize growth and development of children born prematurely.
- Trial name
- SPN (NCT01217164)
- Testing
- no intervention
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Pedro Ernesto
Prolonged Second Stage of Labor, Prolonged Second Stage of Labor Due to Poor Maternal Effort
Vacuum Delivery in All-fours Position vs Traditional Position
The aim of the study is to investigate the safety, clinical efficacy and the maternal/neonatal outcomes of vacuum application in all-fours position compared with supine traditional position, in women undergoing vacuum-assisted…
- Trial name
- VaDe-4 (NCT05612321)
- Testing
- Vacuum application
- Volunteers
- 250 people
- Sponsor
- Ospedale degli Infermi di Biella
Premature Birth
Order Effects of Prematurity Outcome Data
Women recruited from the internet were put in a hypothetical situation of being in labor at 22 weeks of pregnancy, and presented with information in the form of pictographs about survival and disability of babies born at this…
- Trial name
- NCT04269616
- Testing
- Order of pictographs provided to participants, Level of description in survival pictograph
- Where
- United States
- Volunteers
- 839 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Pregnancy, Premature Birth
Prevention of Recurrent Preterm Delivery by a Natural Progesterone Agent
To examine the preterm delivery rate of a preterm delivery high risk group of pregnant women, using once daily natural progesterone agent.
- Trial name
- NCT00329316
- Testing
- Crinone Gel 8%
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Premature Infant
Urine Biomarkers for Renal Function Monitoring in Preterm Infants
The true renal function of preterm infants is difficult to evaluate. Serum creatinine (Cr) levels in infants are unreliable as a detector of renal function in the first few days of life because they may continue to reflect…
- Trial name
- NCT02813109
- Where
- 2 sites in South Korea
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Inha University Hospital
Pregnancy, Labor and Childbirth
Antenatal Delivery Room Visit and Companion Support in Labor
This study evaluated whether an antenatal visit to the delivery room combined with companion support during labor improves comfort and adaptation to childbirth among pregnant women.
- Trial name
- NCT07407309
- Testing
- Antenatal Delivery Room Visit and Companion Support
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Nilgun Avci
Prematurity, Respiratory Distress Syndrome
Comparing Different Delivery Systems of Continuous Positive Airway Pressure in Neonates
The goal of this clinical trial is to compare late preterm newborn lung physiology when supported with different continuous positive airway pressure (CPAP) devices.
- Trial name
- NCT06038565
- Testing
- RAM cannula ventilator CPAP, Occlusive interface bubble CPAP
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Postpartum Hemorrhage, Cesarean Section Complications
Placental Removal Method And Uterine Massage On Preventing Postpartum Hemorrhage
Postpartum hemorrhage is the leading cause of maternal deaths in all over the world, especially in developing and underdeveloped countries. Medical and surgical methods exist for management of bleeding.
- Conditions
- Postpartum Hemorrhage, Cesarean Section Complications, Uterine Atony
- Trial name
- NCT06192836
- Testing
- Manual Removal 1, Manual Removal 2, Controlled Cord Traction 1
- Where
- Turkey (Türkiye)
- Volunteers
- 361 people
- Sponsor
- Busra Lekesiz
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