Clinical trials: Labor Delivery
Neonatal Respiratory Distress, Preterm Birth
Study of the Feasibility of Early Lung Ultrasound in Neonatal Respiratory Distress in Premature Newborns Born Between 32 Weeks of Amenorrhea and 36 Weeks Plus 6 Days of Amenorrhea, Hospitalized in the Neonatal Pediatrics and Intensive Care Units of the Dijon University Hospital
Monocentric study carried out in the Neonatal and Intensive Care Units of the Dijon University Hospital. The objective is to evaluate the feasibility of performing a pulmonary ultrasound within 6 hours after admission in…
- Trial name
- REchoPP (NCT05737095)
- Testing
- Pulmonary ultrasound
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Immature Infant, Essential Fatty Acid Deficiency
Nutrition Therapy in the Immature Infant (ImNuT)
The primary objective of this double-blind randomized study is to assess the effects of an early, enhanced supply of the essential fatty acids (FAs) arachidonic acid (ARA) and docosahexaenoic acid (DHA) on brain maturation…
- Trial name
- ImNuT (NCT03555019)
- Testing
- Formulaid, MCT-oil
- Where
- Norway
- Volunteers
- 121 people
- Sponsor
- Oslo University Hospital
Labor Pain
Prostin and Propess in Induction of Labor
The purpose of the study was to compare the safety and efficacy of two agents used in induction of labor Propess (Controlled release dinoprostone, PGE2, pessary) and Prostin E2 (Dinoprostone vaginal Tablet).
- Trial name
- NCT01635439
- Testing
- Propess, Prostin E2
- Where
- Saudi Arabia
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Preterm Birth, Premature Birth
Cervical Pessary Treatment for Prevention of s PTB in Twin Pregnancies on Children's Long-Term Outcome
Preterm birth (PTB) complicates 13% of all pregnancies worldwide and is the most important cause of neonatal morbidity and mortality. Women with a twin pregnancy are at increased risk of preterm delivery.
- Trial name
- Impetus (NCT03418311)
- Testing
- Cervical Pessary-Group
- Where
- 10 sites in Australia, Germany and 2 more
- Volunteers
- 672 people
- Sponsor
- Bürgerhospital Frankfurt
Premature, Development, Child
Study of the Emergence of Sensory Self-awareness in Premature Newborns Using the Rooting Reflex
The main objective is to demonstrate the presence of the rooting reflex in premature and the emergence of sensory self-awareness in premature by showing a difference in the response of the rooting reflex to external tactile…
- Conditions
- Premature, Development, Child, Rooting Reflex
- Trial name
- PREMATACT (NCT06365164)
- Testing
- Tactile stimulation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Grenoble
Premature Birth
Evaluation of Postural Control in Premature Children
To date, it is largely unknown whether preterm children experience balance problems and whether they have normal postural control.
- Trial name
- NCT04562909
- Testing
- Neurocom balance master device
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Marmara University
Infant,Premature, Feeding; Difficult, Newborn
Nifty Feeding Cup Versus Generic Medicine Cup Preterm Infants Who Have Difficulty Breastfeeding
The investigators will establish an evidence base for the Nifty Feeding Cup by evaluating its effectiveness and caregiver satisfaction.
- Trial name
- NCT03280381
- Testing
- Nifty feeding cup, Generic medicine cup
- Where
- Ghana
- Volunteers
- 200 people
- Sponsor
- PATH
Apnea, Bradycardia
microEEG for Neonatal Apnea, Bradycardia and Desaturation
The study utilizes microEEG (a novel miniaturized, FDA approved EEG device) to prospectively investigate the cerebral electrical activity of infants with Apnea, Bradycardia and Desaturation events.
- Conditions
- Apnea, Bradycardia, Premature Birth, Seizures
- Trial name
- NCT02436616
- Testing
- microEEG
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Bio-Signal Group Corp.
Infant, Newborn, Infant, Low Birth Weight
In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants
This study examined the effect of magnesium sulfate (MgSO4) exposure on adverse outcome in extremely low birth weight (ELBW) infants.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- MgSO4 (NCT01203501)
- Where
- 15 sites in United States
- Volunteers
- 1,339 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Labor Pain
Best Beginnings for Babies Birth Sister Program Evaluation
Peer support during labor, birth and the perinatal period (also known as "doula" support) has been shown in some studies to reduce cesarean rates, postpartum depression and increase breastfeeding rates.
- Trial name
- BBB (NCT02550730)
- Testing
- Birth Sisters Best Beginnings for Babies, Usual maternity care
- Where
- United States
- Volunteers
- 411 people
- Sponsor
- Boston Medical Center
Preterm Birth, Complication of Prematurity
Single Dose Antenatal Corticosteroids (SNACS) for Women at Risk of Preterm Birth
Antenatal corticosteroids (ACS) reduce the risks of neonatal death and morbidities, such as respiratory distress syndrome, in preterm infants.
- Conditions
- Preterm Birth, Complication of Prematurity, Obstetric Labor, Premature, Obstetric Labor Complications
- Trial name
- SNACS Pilot (NCT04494529)
- Testing
- 24 mg betamethasone
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Prematurity
Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized Trial
The goal of this multi-center randomized, parallel group trial is to determine the effect of human milk diets ranging between 180 and 200 mL/kg/day on the body composition outcomes of moderately preterm infants born between 27…
- Trial name
- MAGIC (NCT06420531)
- Testing
- Human milk
- Where
- 4 sites in United States
- Volunteers
- 486 people
- Sponsor
- University of Alabama at Birmingham
Birth Outcome, Adverse, Labor Long
How Long Can Labor Last? Person Centred Care During Labor to Increase Safety for Women and Newborn
"How long will my labor last" is a very common question for midwives who care for women during birth. To evaluate safe labor duration largely determines management and care during birth.
- Conditions
- Birth Outcome, Adverse, Labor Long, Labor Complication, Maternal Injury
- Trial name
- NCT06420453
- Where
- Sweden
- Volunteers
- 300,000 people
- Sponsor
- Karolinska Institutet
Postpartum Period, Depression
Relationship Between Postpartum Mood Disorders and Delivery Experience
The purpose of this study is to evaluate potential risk factors for developing postpartum depression or posttraumatic stress disorder during the first year postpartum in patients who have no preexisting history of PTSD or PPD.
- Conditions
- Postpartum Period, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NCT03004872
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Michigan
Preterm, Necrotizing Enterocolitis
The Effect of Probiotics Added to the Mother's Diet on Preterm Babies
Abstract According to the definition by World Health Organization; births before the completion of the 37th gestational week are called, preterm birth.
- Conditions
- Preterm, Necrotizing Enterocolitis, Late-Onset Neonatal Sepsis, Breast Milk Expression
- Trial name
- NCT06118801
- Testing
- Probiotic Product Supplement
- Volunteers
- 50 people
- Sponsor
- Harran University
HIE - Hypoxic - Ischemic Encephalopathy, Perinatal Anoxic-ischemic Brain Injury
Biomarkers Study in Infants With Prior Neonatal Brain Injury
This research focuses on the long-term cognitive development of children, including healthy infants and those who had a perinatal brain injury.
- Conditions
- HIE - Hypoxic - Ischemic Encephalopathy, Perinatal Anoxic-ischemic Brain Injury, Premature Birth, Healthy Participants
- Trial name
- NCT07413900
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Patent Ductus Arteriosus
Early Treatment Versus Expectative Management of PDA in Preterm Infants
Much controversy exists about the optimal management of a patent ductus arteriosus (PDA) in preterm infants, especially in those born at a gestational age <28 weeks and/or a birth weight ≦1000 grams due to a lack of evidence for…
- Trial name
- BeNeDuctus (NCT02884219)
- Testing
- Ibuprofen, Expectative Management, Indomethacin
- Where
- 13 sites in Belgium, Netherlands
- Volunteers
- 273 people
- Sponsor
- Radboud University Medical Center
Prematurity
Preterm Donor Human Milk Supplementation of Mother's Own Milk in VLBW Infants
This prospective randomized controlled trial aims to investigate whether feeding very low birth weight (VLBW) infants with Mother's own milk (MOM) supplemented with either preterm (PDM) or term donor milk (TDM), when MOM is…
- Trial name
- NCT05675397
- Testing
- donor human milk
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Premature Birth
Development of a Digital Tool for the Individualization of Speech Therapy Care for Premature Newborns
The study concerns the creation and implementation of a digital tool presenting the various orofacial stimuli that can be offered to premature newborns.
- Trial name
- NEORTHO (NCT05992181)
- Testing
- NEORTHO
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Sud Francilien
Gestational Diabetes, Pregnancy Complications
Gestational Diabetes Monitoring and Management
The primary goal is to predict the clinical outcomes of mother and baby using blood glucose and other routinely collected clinical data in pregnancy to predict adverse outcomes at birth in women with GDM.
- Conditions
- Gestational Diabetes, Pregnancy Complications, Pregnancy in Diabetic, Pregnancy, High Risk
- Trial name
- NCT06963528
- Where
- United Kingdom
- Volunteers
- 1,800 people
- Sponsor
- University of Oxford
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