Clinical trials: Labor Epidural Analgesia
Labor Pain
Epidural Analgesia in Different Cervix Diameter and the Rate of Cesarean Delivery
Epidural analgesia in the early stage of labor at cervix < 4.0cm was considered as a risk period for increasing the rate of cesarean delivery.
- Trial name
- EACDRCD (NCT00677274)
- Testing
- Epidural labor analgesia
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Nanjing Medical University
Anesthesia, Analgesia
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients.
- Trial name
- NCT05514431
- Testing
- Epidural, Dural Puncture Epidural (DPE) technique, Combined Spinal-Epidural (CSE) technique
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor-3
Until recently, at Mount Sinai Hospital (MSH), epidural analgesia for labor pain was delivered with a pump that could only provide continuous infusion of the freezing medication in combination of pushes of medication activated by…
- Trial name
- NCT02887222
- Testing
- Bupivacaine
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Pain
Epidural Analgesia Versus IV Meperidine for Labor Pain Control
60 female that care for pain control during second stage of delivery, will choose between epidural or systemic analgesia. Continuous ECG (3 lead)monitoring will be recorded during the second stage for 10 minutes.
- Trial name
- NCT00296751
- Testing
- ECG recording, Epidural catheter insertion, Intravenous meperidine injection
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Labor Long, Labor Pain
Comparison of Combined Spinal-epidural Analgesia Versus Epidural Analgesia for Pain Management During Labor
The investigators want to compare the safety and efficacy between the combined spinal-epidural analgesia and epidural analgesia during labor.
- Conditions
- Labor Long, Labor Pain, Labor Fetal Anoxia
- Trial name
- NCT03600272
- Testing
- Combined spinal-epidural analgesia, Epidural analgesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Deng Dongrui
Labor Pain
Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal Epidural
Neuraxial analgesia has shown to be the gold standard for effective labor pain relief, offering numerous benefits including enhanced pain control and maternal satisfaction.
- Trial name
- NCT06572241
- Testing
- Intrathecal morphine
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Obesity, Morbid, Pregnancy
3D Ultrasound-guided Labor Epidural Analgesia in the Morbid Obese Parturient
This study will be a randomized control study, with the objective to evaluate epidural analgesia success rates between the two methods (Blind Approach versus Accuro Device).
- Conditions
- Obesity, Morbid, Pregnancy, Pain
- Trial name
- NCT03405311
- Testing
- Rivanna Accuro 3D Ultrasound Device, Palpation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Labor Pain
Programmed Intermittent Epidural Bolus Versus Continuous Infusion in Labour Analgesia
This study aims to establish if programmed intermittent epidural bolus combined to patient controlled analgesia in labour analgesia will lower the hourly bupivacaine consumption when compared to continuous infusion combined with…
- Trial name
- NCT03730753
- Testing
- Programmed intermittent epidural bolus, Continuous infusion
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Painless Labor, Epidural Analgesia
The Post Cesarean Section Analgesic Effect of Various Quadratus Lumborum Block Approaches
included patients were divided into 4 groups and each group received a mode of post cesarian section analgesia and pain was assessed by visual analogue scale at rest and movement. 1. st group epidural analgesia 2.
- Conditions
- Painless Labor, Epidural Analgesia, Cesarean Section
- Trial name
- NCT06393192
- Testing
- Epidural analgesia (EA) only group, Quadratus lumborum block (QL2), Quadratus lumborum block 3(QL3)
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Labor Pain
A Comparison of Epidural Analgesia: Continuous Infusion Versus Programmed Intermittent Boluses
The analgesic approach in labor can be done in different ways, among which the neuraxial approach has shown the best analgesic results and fetal outcomes.
- Trial name
- NCT02510287
- Testing
- Bupivacaine and Fentanyl Initial Dose, Bupivacaine and Fentanyl: Continuous Epidural Infusion, Bupivacaine and Fentanyl: Programmed Intermittent Epidural Bolus
- Where
- Colombia
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Anesthesia, Epidural, Hypotension
Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension
The purpose of this pilot trial is to examine the feasibility and ease of use of monitoring by ClearSight in laboring and delivering patients with the intent to compare time-to-treatment of hypotension between conventionally…
- Trial name
- NCT05906368
- Testing
- ClearSight HPI Monitoring system, Standard of Care Blood Pressure Monitoring
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Labor Pain
Gender of Anesthesiologist and Time to Labor Epidural
The goal of this retrospective cohort study is to learn about wether the gender of the anesthetist affects time to epidural anesthesia (EDA) for laboring women . The main questions it aims to answer are: 1.
- Trial name
- NCT05744570
- Testing
- Epidural anesthesia
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Umeå University
Labor Pain, Epidural Analgesia
Different Spinal Needles Sizes and Dural Puncture Epidural For Labor Analgesia
The rationale behind the dural puncture epidural (DPE) technique lies in the fact that a dural perforation with a spinal needle purportedly creates a conduit for accelerated translocation of local anesthetics from the epidural to…
- Trial name
- NCT03389945
- Testing
- 25G Dural Puncture Epidural Block, 27G Dural Puncture Epidural Block
- Where
- 2 sites in Chile
- Volunteers
- 140 people
- Sponsor
- University of Chile
Labour Pain
Development of a Multi-attribute Health Index: to Measure the Quality of Labour Analgesia: The QLA Index
The findings of this research will be used to develop a scale for measuring the quality of epidural pain relief achieved during labour and vaginal delivery.
- Trial name
- NCT01177046
- Where
- Canada
- Volunteers
- 752 people
- Sponsor
- Sunnybrook Health Sciences Centre
Labor Pain
Dexmedetomidine for Intermittent Epidural Boluses Versus Continuous Epidural Infusion for Labour Epidural Analgesia
The aim of this study is to compare two modes of labour epidural analgesia: programmed intermittent epidural boluses (PIEB) versus continuous epidural infusion (CEI), with patient controlled epidural analgesia (PCEA), using…
- Trial name
- NCT05781854
- Testing
- Epidural analgesia with bupivacaine and dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor
Until recently, at Mount Sinai Hospital, epidural analgesia for labor pain was delivered with a pump that could only provide continuous infusion of the freezing medication in combination of pushes of medication activated by the…
- Trial name
- NCT02550262
- Testing
- Bupivacaine, Fentanyl, Infusion pump
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Pain, Analgesia
Effect of Epidural Analgesia During Labor on Force of Maternal Push
There are multiple factors that determine progress of normal vaginal delivery. Frequency, duration and strength of uterine contractions are important for progress throughout labor, and abdominal wall muscle contractions…
- Conditions
- Labor Pain, Analgesia, Maternal; Procedure
- Trial name
- NCT04888858
- Testing
- Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Labor Pain, Pain
The Effects of Intermittent Epidural Bolus on Fever During Labor Analgesia
Epidural analgesia is associated with maternal intra-partum fever during labor. Intermittent epidural injections appear to reduce the incidence of maternal intra-partum fever compared to continuous epidural infusion during labor…
- Conditions
- Labor Pain, Pain, Neurologic Manifestations, Signs and Symptoms
- Trial name
- EIEBFLA (NCT01708668)
- Testing
- Epidural analgesia, Combined spinal-epidural analgesia, Continuous epidural infusion
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- ShanWu Feng, M.D.
Labor Pain, Breakthrough Pain
Development of Variable Volume Automated Mandatory Boluses for Patient-controlled Epidural Analgesia During Labour
A novel epidural delivery regimen was developed: Variable volume automated mandatory bolus (AMB) (VVAMB) will advance individualisation of labour epidural analgesia, by which a larger volume of bolus may contribute to better…
- Trial name
- VVAMB (NCT04011150)
- Testing
- Epidural infusion pump, Ropivacaine, Fentanyl
- Where
- Singapore
- Volunteers
- 197 people
- Sponsor
- KK Women's and Children's Hospital