Clinical trials: Labor Epidural Analgesia
Epidural Anesthesia
Real-time Ultrasound Guided Labor Epidural Placement
Specific Aim: The purpose of this study is to determine if labor epidural placement using real-time (concurrent) ultrasound guided placement is superior to the conventional "standard" epidural technique without the use of…
- Trial name
- NCT00811304
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Labor Pain
Characteristics of the Tsui Test and Pressure Waveform to Confirm Epidural Catheter Placement in Parturients With BMI ≥50 kg/m2
The prevalence of obesity has increased worldwide, and the anesthetic care of patients with obesity remains a challenge for providers despite advances.
- Trial name
- NCT05361512
- Testing
- Tsui test, epidural waveform analysis
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Fetal Bradycardia, Hypertonic Uterine
Plasmatic Catecholamines: Randomized Controlled Trial Comparing Epidural Versus Combined Spinal-epidural
Combined spinal-epidural (CSE) for labor analgesia has been associated with fetal bradycardia and uterine hypertonia, possibly due to asymmetric decrease in catecholamine levels, when compared with epidural analgesia (EP).
- Conditions
- Fetal Bradycardia, Hypertonic Uterine, Catecholamines
- Trial name
- NCT02666794
- Testing
- Epidural bupivacaine with vasoconstrictor 0.125%, Epidural sufentanil, Placement of the epidural catheter
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Labor Pain
Effect of Prenatal Education on Perceptions of Epidural Acceptance
The purpose of the study is to determine if targeted prenatal educational program on womens' perceptions of epidural increases the acceptance of intrapartum epidural analgesia relative to the control group.
- Trial name
- NCT01709591
- Testing
- Prenatal education
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Santa Clara Valley Health & Hospital System
Pregnancy, Labor Pain
Epidural Volume Extension During a Combined Spinal-Epidural Technique for Labor Analgesia.
Combined spinal-epidurals (CSE) involve the injection of pain relief medication into the cerebral spinal fluid (CSF) and the insertion of an epidural catheter in the epidural space to continue to give pain relief medication.
- Trial name
- NCT01810406
- Testing
- CSE with 10 ml EVE, CSE without EVE
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- IWK Health Centre
Postpartum Depression (PPD), Labor Analgesia
Maternal Expectations on Labor Analgesia and Risk of Postpartum Depression: An Observational Study
Postpartum Depression (PPD) is defined as the development of depression at any time during the first year after childbirth¹. Its prevalence ranges from 15% to 20%.
- Conditions
- Postpartum Depression (PPD), Labor Analgesia, Expectations
- Trial name
- NCT07292649
- Testing
- Epidural analgesia, Spinal analgesia for labour pain, No neuraxial analgesia
- Where
- Italy
- Volunteers
- 3,640 people
- Sponsor
- University of Padova
Epidural, Labor Pain
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Labour pain can be intensified for labour inductions and women undergoing inductions often have earlier and more frequent requests for analgesia.
- Conditions
- Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn, Obstetric Anesthesia Problems
- Trial name
- NCT04011098
- Testing
- Epidural Fentanyl Bolus, Standard Epidural Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Fetus or Neonate Affected by Maternal Epidural Anesthesia During Labor and Delivery
Pulse Pressure and Post-epidural Fetal Heart Rate Changes
Epidural anesthesia, the most common method of pain control in labor, can contribute to alterations in maternal blood pressure and/or fetal heart rate changes.
- Trial name
- NCT02565485
- Testing
- Lactated Ringer's
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- MetroHealth Medical Center
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Labor for Induction Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women scheduled for an induction of labor, with whom analgesia is maintained with a combined spinal…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982851
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pregnancy
Use of Peanut Labor Ball Following Epidural Anesthesia
The purpose of the study is to look at the impact of using the Peanut Labor Ball (PLB) after epidural anesthesia in patients who have never given birth.
- Trial name
- NCT02190591
- Testing
- Peanut Labor Ball
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Pregnancy
PIEB vs CEI for Labor Analgesia: An MLAC Study
Utilizing a 'minimal local analgesic concentration (MLAC) study' design to first determine the relative potency of Programmed Intermittent Epidural Bolus (PIEB) compared to Continuous Epidural Infusion (CEI) and secondly to…
- Trial name
- NCT02573597
- Testing
- Bupivacaine, Sufentanil
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Stanford University
Labor Analgesia
Comparison of Programmed Intermittent Epidural Bolus With Continuous Epidural Infusion for Labor Epidural Analgesia
Sixteen million babies were born in 2010, approximately half were by cesarean. Labor analgesia should be the first choice for these parturients based on the consideration of security and humanization.
- Trial name
- NCT02873091
- Testing
- Epidural analgesia, Continuous epidural infusion, Intermittent epidural bolus
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Nanjing Maternity and Child Health Care Hospital
Pregnancy Related, Epidural; Anesthesia, Headache
Inertial Sensors for Obstetrical Walking Epidural Tracking
Freedom of movement and the ability to walk are crucial during the first stage of labor, potentially reducing labor duration, cesarean section risk, epidural analgesia use, and bladder catheterization.
- Conditions
- Pregnancy Related, Epidural; Anesthesia, Headache, Labor Complication
- Trial name
- MOTION-EASE (NCT06471790)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Pregnancy
Does Ultrasound Help Junior Anesthesia Residents With Placement of Labor Analgesia in Pregnant Patients
The investigators believe that ultrasound guided CSE technique will help junior resident rotating for the first time on the labor and delivery floor to place more accurately the epidural needle in the midline position as compared…
- Trial name
- NCT02747238
- Testing
- Ultrasound, No ultrasound, Epidural infusion
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Labor Pain
The Application of Analgesia Nociception Index as an Objective Labor Pain Assessment During Epidural Analgesia
Epidural analgesia is considered an effective and safe method for obstetric pain control. Currently, self-assessment pain scales remain to be the gold standard in labor pain evaluation after the administration of epidural…
- Trial name
- NCT03975816
- Testing
- Analgesia nociception index
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Changhua Christian Hospital
Epidural, Analgesia
Epidural Analgesia and Delivery of Second Twin
Over an 8-year period, 124 twin pregnancies at gestational age ≥32 weeks with both twins presenting as a vertex and eligible for vaginal delivery were reviewed.
- Conditions
- Epidural, Analgesia, Labor Pain
- Trial name
- Epidural (NCT04608006)
- Testing
- Bupivacaine-fentanyl
- Where
- Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Abdelrady S Ibrahim, MD
Labor, Analgesia, Epidural
Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia
Epidural chloroprocaine is often used in obstetrical anesthesia because of its fast onset and short duration. These properties make it an ideal drug to use for epidural anesthesia in patients undergoing postpartum tubal ligation.
- Trial name
- NCT00487084
- Testing
- Morphine-CP-saline (MCS), saline-2CP-morphine (SCM), saline-lidocaine-morphine (SLM)
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Labor Pain
Differential Sensory Block During Labor Epidural Analgesia: a Prospective Observational Study to Investigate the Relationship of Lower and Upper Sensory Block Levels to Cold With Sensory Block to Pinprick and Light Touch
Epidural analgesia remains the gold standard for pain control during labor and delivery. Proper assessment of an epidural's level of blockade is important for providing safe and effective analgesia.
- Trial name
- NCT05187962
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labour Pain
Combined Spinal-Epidural Versus Traditional Labor Epidural
The purpose of this study to compare the use of spinal-epidural versus traditional labor epidural on maternal and fetal effects.
- Trial name
- NCT00151346
- Testing
- Bupivacaine and Fentanyl (for CSE), Bupivacaine and Fentanyl (for traditional epidural)
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Urinary Retention
Urinary Retention After Vaginal Delivery With Epidural Anesthesia.
The investigators intend to compare the rate of urinary retention among female patients after vaginal delivery under epidural anesthesia, depending on bladder catheterization type, either by a foley catheter inserted adjacent to…
- Trial name
- NCT02865551
- Testing
- Foley catheter, Short term catheter, Epidural anesthesia
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Rambam Health Care Campus