Clinical trials: Labor Epidural Analgesia
Labor Pain, Dural Puncture Epidural Technique
Two Different Sized Spinal Needles DPE vs Conventional Epidural Technique
DPEA (Dural Puncture Epidural Analgesia) is an alternative to the conventional epidural analgesia and technically a Combined Spinal Epidural (CSE) with omission of intrathecal drugs administration.
- Trial name
- NCT07708909
- Testing
- Dural Puncture Epidural Analgesia 27G, Dural Puncture Epidural Analgesia 25G, Conventional epidural
- Volunteers
- 240 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Labor Pain
Tetracaine Combined Spinal Epidural (CSE) Versus Bupivacaine CSE
The investigators hypothesis is that spinal tetracaine with fentanyl and epinephrine used for CSE labor analgesia volume will last a significantly longer period of time that that of spinal bupivacaine with fentanyl.
- Trial name
- NCT01005459
- Testing
- Tetracaine, Bupivacaine
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Wake Forest University
Labor Pain
The Effect of Metrics Based Performance Based Progression in Provision of Labor Epidural Analgesia
Procedural skills are an important determinant of clinical outcomes for certain patient groups. Training for procedural skills in the medical profession is still largely based on an apprenticeship model.
- Trial name
- NCT02185079
- Testing
- Training to proficiency, Conventional training
- Where
- Ireland
- Volunteers
- 16 people
- Sponsor
- Cork University Hospital
Pain
Determination of the Effective Volume of 0.125% Bupivacaine-fentanyl 5mcg/mL in Labour Epidurals
Different medications can be used as analgesics in labor epidurals. Bupivacaine is one of the most commonly used drugs for that purpose. The efficacy of a certain medication injected epidurally depends on the dose that is given.
- Trial name
- NCT01972269
- Testing
- Bupivacaine-fentanyl, Lidocaine
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Post-Dural Puncture Headache
Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study
The purpose of this study is to determine the effect of 19g versus =>18g traditional Tuohy-type epidural needles on the incidence and severity of postdural puncture headache (PDPH).
- Trial name
- NCT00370604
- Testing
- 19g Tuohy-type epidural needle, 23g catheter, => 18g Tuohy-type needle
- Where
- 4 sites in Canada
- Volunteers
- 1,081 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Labor Pain
Ten-year Practice of Labor Pain Control in China
Since 1999, labor pain control has being performed in China, and the initial time of analgesia is at the cervix >= 2 cm. Meanwhile, American Society of Obstetrics \& Gynecology recommended that the labor analgesia with neuraxial…
- Trial name
- POPIC (NCT00776581)
- Testing
- CSEA with PCA, CSEA with IBI, EA with PCA
- Where
- China
- Volunteers
- 40,000 people
- Sponsor
- Nanjing Medical University
Prolonged Labor, Healthy
Epidural Analgesia on Electrophysiological Function
Combined spinal-epidural analgesia (CSEA) is sometimes used for difficult births, but whether it contributes to postpartum pelvic muscle disorder is unclear.
- Conditions
- Prolonged Labor, Healthy, Pelvic Floor Disorders
- Trial name
- NCT02334150
- Testing
- CSEA (ropivocaine and sufentanil)
- Where
- China
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Nanjing Maternity and Child Health Care Hospital
Labor Pain
Parturient Controlled Epidural Analgesia (PCEA) With or Without a Basal Infusion for Early Labor
Patient Controlled Epidural Analgesia is a widely used and effective means of adult pain management. However, Parturient Controlled Epidural Analgesia (PCEA) is a relatively new approach to pain control for the women in labor.
- Trial name
- NCT00871442
- Testing
- No Basal Infusion, Basal infusion, PCEA solution (bupivacaine and fentanyl)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neil Roy Connelly, MD
Labor Pain, Nociceptive Pain
Nociception Level Index (NOL Index) for Obstetrical Pain Assessment Under Epidural Analgesia.
Pain has been defined by the International Association for the Study of Pain (IASP) as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage".
- Conditions
- Labor Pain, Nociceptive Pain, Epidural Analgesia, NOL Index
- Trial name
- NCT05898737
- Testing
- NOL-Index
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Effects of; Anesthesia, in Labor and Delivery
Intrathecal Dexamethasone and Labor Analgesia
To evaluate the effectiveness of adding dexamethasone to intrathecal levobupivacaine in combined spinal epidural (CSE) analgesia during vaginal delivery.
- Trial name
- NCT02588417
- Testing
- Dexamethasone, Levobupivacaine
- Volunteers
- 80 people
- Sponsor
- ahmed elsakka
Labor Pain
Use of Standardized Algorithm for the Management of Epidural Analgesia for Labor and Delivery
Programmed Intermittent Epidural Bolus (PIEB) has become a standard technique for labour analgesia in many departments of anesthesia.
- Trial name
- NCT04814199
- Testing
- Algorithm
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Analgesia
Do Epidurals Placed at a Lower Level Improve Labor Analgesia?
The investigators wish to compare the analgesia provided by epidurals placed high in the lumbar spine versus epidurals place low in the lumbar spine.
- Trial name
- NCT00954317
- Testing
- epidural placed low, high epidural
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Royal Victoria Hospital, Canada
Labor, Obstetric
Nutrition as a Determinant of Labor Outcome
This is a randomized, double-blind trial looking at how nutrition intake is associated with labor progress and complications.
- Trial name
- NCT00367549
- Testing
- Energy-containing soft drink
- Where
- Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Labor Pain, Labor Analgesia
Combined Implementation of Dural Puncture Epidural and Programmed Intermittent Epidural Bolus for Labor Analgesia
This study intends to carry out a prospective, randomized double-blind study to evaluate the safety and efficacy of the combined implementation of Dural puncture epidural (DPE) technique and Programmed intermittent epidural bolus…
- Trial name
- NCT03366935
- Testing
- EPL and CEI, DPE and CEI, DPE and PIEB
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai First Maternity and Infant Hospital
Labor Pain
Initiation Ropivacaine Dose for Labor Analgesia Via Double Dural Puncture Epidural Technique
This study aims to determine the 90% effective dose (ED₉₀) of an initial regimen of 0.1% ropivacaine combined with 0.3 μg/mL sufentanil, administered via the double dural puncture epidural technique for epidural labor analgesia.
- Trial name
- NCT07882004
- Testing
- 0.1% Ropivacaine
- Volunteers
- 30 people
- Sponsor
- General Hospital of Ningxia Medical University
Assess Women Awareness and Fear About EDA for Labor
"Awareness, Preconception, and Fear of Epidural Analgesia Among Childbearing Women in Saudi Arabia."
The aim of our study is to measure the level of awareness, preconceptions, and level of fear regarding epidural analgesia among childbearing women in KKUH in Riyadh.
- Trial name
- NCT05596604
- Testing
- survey- no intervention
- Where
- Saudi Arabia
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- King Khalid University Hospital
Labor Pain
The 90% Effective Initial Volume for Labor Analgesia Under Double Dural Puncture Epidural Technique
This study aims to determine the 90% effective initial volume of 0.1% ropivacaine for labor analgesia under the double dural puncture epidural technique
- Trial name
- NCT07894770
- Testing
- 0.1% Ropivacaine
- Volunteers
- 30 people
- Sponsor
- General Hospital of Ningxia Medical University
Labor Pain
CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Analgesia in labour is not readily available in many parts of Sub-Saharan Africa. The overall cost of Epidural services in terms of human personnel and financial implication makes this inaccessible to many women in labour.
- Trial name
- SSS (NCT03117595)
- Testing
- Bupivacaine-fentanyl, Bupivacaine-fentanyl morphine
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Beckley
Anesthesia, Epidural
Epidural Pressure Waveform Recordings by the CompuFlo® Cath-Checker System
The purpose of this single arm, open label study will be to evaluate whether the dwell time of the epidural catheter, patients' position, the presence of active labor contractions and the priming volume of the epidural catheter…
- Trial name
- NCT04240912
- Testing
- CompuFlo Epidural Computer Controlled System
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- European e-Learning School in Obstetric Anesthesia
Analgesia
Effect of Auto-Bolus Interval on Analgesic Quality During Labor Analgesia With Dural Puncture Epidural
It is aimed in this study to compare the effect of changing the interval time for programmed auto boluses of local anaesthetics on the total anesthetic consumption and quality of labor analgesia with dural puncture epidural…
- Trial name
- NCT06329713
- Testing
- Group I: 30 Min Interval Time, Group II: 60 Min Interval Time
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ataturk University