Clinical trials: Labor Stage, Second
Labor Stage, Second, Labor and Delivery
Visual Biofeedback Through Transperineal Ultrasound During the Expulsive Phase of Labour to Improve Maternal Childbirth Satisfaction
Childbirth is generally regarded as a positive life-changing experience. Up to 44% of women may however experience this as a traumatic event, with 3% suffering from post-traumatic stress disorder after childbirth.
- Conditions
- Labor Stage, Second, Labor and Delivery, Satisfaction With Care, Childbirth
- Trial name
- RCT:VB-TPU (NCT06847308)
- Testing
- visual biofeedback through trans-perineal ultrasound
- Where
- Belgium
- Volunteers
- 488 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Labor Onset and Length Abnormalities
Goal-directed Labor Epidural Analgesia Maintenance
The GLEAM trial is a multicenter, pragmatic, cluster-randomized trial to assess the effects of programmed intermittent epidural bolus versus continuous epidural infusion on the rate of spontaneous vaginal delivery and several…
- Trial name
- GLEAM (NCT05255263)
- Testing
- PIEB, CEI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Labor, Second Stage, Vaginal Delivery
USE OF PERINEAL MIRROR DURING THE SECOND STAGE OF LABOR
Objective: This study was designed to evaluate the effect of perineal mirror use during the second stage of labor on the duration of the second stage, postpartum recovery, and perceived pain, support, and control levels during…
- Conditions
- Labor, Second Stage, Vaginal Delivery, Primiparity, Perineal Mirror Use
- Trial name
- NCT07659249
- Testing
- Perineal Mirror
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Delivery Complication, Cesarean Delivery Affecting Fetus
Time of Oxytocin Initiation at 2nd Stage of Labor and Adverse Outcomes
Early oxytocin administration at the 2nd stage of labor is associated with a higher rate of vaginal delivery, shorter second stage duration, and fewer adverse maternal and neonatal outcomes.
- Trial name
- NCT06181396
- Testing
- Oxytocin
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Labor Pain, Labor; Prolonged, Second Stage
Remifentanil vs. Combined Spinal-epidural Analgesia for Labor Analgesia and Progress of Labor in Multiparous
Remifentanil may be an ideal drug for labor analgesia due to its pharmacodynamic and pharmacokinetic profile. As compared to epidural analgesia, it demonstrated satisfactory for pain relief at the beginning of labour with a…
- Conditions
- Labor Pain, Labor; Prolonged, Second Stage, Labor; Prolonged, First Stage
- Trial name
- NCT02963337
- Testing
- remifentanil, combined spinal-epidural analgesia
- Where
- Slovenia
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Labor, Second Stage of Labor
The Effect of Chocolate Consumption During Labor on Second Stage Duration
Childbirth is an energy-intensive physiological process, requiring sustained effort comparable in intensity to moderate physical activity.
- Conditions
- Labor, Second Stage of Labor, Pregnancy
- Trial name
- NCT07375836
- Testing
- 50 g of milk chocolate cocoa content 25-30%
- Volunteers
- 180 people
- Sponsor
- Hillel Yaffe Medical Center
Cold Compress
Effect of Perineal Massage Combined With Cold Compress in the Second Stage on the Delivery Outcome of Primipara
Objective: The aim of this study was to investigate the effect of perineal massage and cold compress in second stage on the delivery outcome of primipara.
- Trial name
- NCT05350670
- Testing
- Perineal massage and cold compress
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Labor Complication, Avulsion
The Association Between Kristeller Maneuver and Pelvic Floor Trauma After Vaginal Delivery
We want to investigate the association between fundal pressure in the second stage and the risk of levator ani muscle (LAM) injury.
- Trial name
- NCT03752879
- Testing
- Fundal Pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Perineal Tear Resulting From Childbirth
Perineal Massage and Warm Compresses - RCT for Reduce Perineal Trauma During Labor
The aim of this study is to evaluate the effect of a combined perineal massage and warm compresses intervention on the perineum integrity during second stage of labor.
- Trial name
- PeMWaC (NCT05854888)
- Testing
- Perineal Massage and Warm Compresses (PeMWaC), Control Group (Hands-on)
- Where
- Portugal
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Delivery, Obstetric, Labor, Obstetric
Effects of a Lateral Position With Hip Flexion and Femoral Internal Rotation During the Second Stage of Labor in Nulliparous Women Receiving Epidural Analgesia
This randomized clinical study evaluated the effects of a lateral position with hip flexion and femoral internal rotation during the second stage of labor in nulliparous women receiving epidural labor analgesia.
- Trial name
- NCT07745192
- Testing
- Lateral Position With Hip Flexion and Femoral Internal Rotation, Conventional Lateral Position
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Labor, Pelvic Floor Disorder
Pelvic Floor Ultrasound Before Induction of Labour and Labour Outcome
Pregnancy and vaginal birth are the main causes of pelvic floor disorders such as urinary incontinence and pelvic organ prolapse.
- Conditions
- Labor, Pelvic Floor Disorder, Labor Stage, Second, Induced Labor
- Trial name
- LEVATOR-IOL (NCT07797387)
- Testing
- Three-dimensional transperineal pelvic floor ultrasound
- Where
- Italy
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Labor, Second Stage
Urinary Catheterization and Second Stage of Labor
Labor is divided into three stages: the first stage is from labor onset until full dilation, second stage is from full dilation until delivery of the baby, and the third stage from the delivery of the baby until the delivery of…
- Trial name
- cath2stage (NCT02198157)
- Testing
- urinary catheterization
- Where
- Israel
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Raed Salim
Labor; Prolonged, Second Stage, Episiotomy Wound
The Impact of Different Skin Suture Methods in Episiotomy Repair on Healing and Pain
Episiotomy is the intentional incision of the perineum during vaginal birth in order to accelerate the active phase of labor. This study aimed to compare various skin closure techniques in episiotomy repair.
- Trial name
- NCT06379048
- Testing
- Mattress Suturing, Primary Suturing, Continuous Subcutaneous Suturing
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Labor, First Stage, Labor, Second Stage
Effect of Dianatal Obstetric Gel (Cross-linked Polyacrylic Acid) on Outcomes in Vaginal Delivery
Perineal massage at the end of labor stage 2 has been investigated in 2 randomized controlled trials using a water soluble lubricant.
- Trial name
- NCT01546129
- Testing
- Dianatal Obstetric Gel (Cross-linked polyacrylic acid)
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Sphincter (Anal); Perineal Rupture, Obstetric, Perineal Tear
One Plus One Equals Two, Will That do?
A new clinical practice to reduce perineal trauma has been adopted by many maternity wards in Sweden. This practice involves collegial midwifery assistance during the second stage of labor and the birth of the baby.
- Conditions
- Sphincter (Anal); Perineal Rupture, Obstetric, Perineal Tear, Pelvic Floor Disorders, Experience, Life
- Trial name
- Oneplus (NCT03770962)
- Testing
- Two midwives
- Where
- 4 sites in Sweden
- Volunteers
- 3,058 people
- Sponsor
- Region Skane
Prolonged Second Stage of Labor
Use of Lubricant Gel to Shorten the Second Stage of Labor During Vaginal Delivery
This experimental study aims to evaluate whether the application of obstetric lubricant gel during vaginal delivery can significantly reduce the duration of the second stage of labor, preserve perineal integrity, and decrease the…
- Trial name
- OBY-GEL (NCT07428317)
- Testing
- Obstetric Lubricant Gel, Standard Active Management of Second Stage
- Where
- Honduras
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Labor Pain
Epidural Fentanyl for 2nd Stage Labor Analgesia
This study is being done to investigate if there is more effective pain relief during the latter stages of labor and delivery when epidural fentanyl 100mcg is administered compared to epidural fentanyl 20mcg.
- Trial name
- NCT03120780
- Testing
- Fentanyl 20 mcg, Fentanyl 100 mcg
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Ohio State University
Parturition, Obstetric; Injury Pelvic Floor
Evaluation of the Effectiveness of Obstetric Lubricant Gel in Labor in Nulliparous and Primiparous Women: A Randomized Controlled Study
The investigators hypothesized that the application of lubricant gels at the beginning of the active phase of the labor may reduce duration of the delivery and episiotomy rates.
- Trial name
- NCT06069596
- Testing
- Natalis Obstetric Lubrican Gel
- Volunteers
- 220 people
- Sponsor
- Ankara University
Labor Pain
Effectiveness of Breathing Exercises During the Second Stage of Labor
To determine effectiveness of breathing exercises for pregnant women during the second stage of labor on maternal pain, duration of labor, dyspnea, oxygen saturation (SPO2) and the first-minute Appearance, Pulse, Grimace…
- Trial name
- NCT04556643
- Testing
- Breathing exercises
- Where
- Pakistan
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Prolonged Second Stage of Labor
Validation of Ultrasound "Angle of Progression" Measurement to Decrease the Cesarean Rate
Ultrasound during labor and measurement of Angle of progression showed extensive prospective and retrospective publications since 2010.
- Trial name
- DELIVERY (NCT05779735)
- Testing
- Transperineal ultrasound measurements of AOP
- Where
- 7 sites in France
- Volunteers
- 182 people
- Sponsor
- Hospital St. Joseph, Marseille, France