Clinical trials: Labor and Delivery Complication
Preterm Birth
E-health-supported Diagnostic and Intervention in Preterm Born Children and Their Families
The app-based diagnostic and support approach with a focus on mental and somatic symptoms is intended to strengthen the resilience of premature born children and families and to identify risk and resilience factors.The overall…
- Trial name
- NeoUp2 (NCT06939192)
- Testing
- Intervention Group (APP), Treatment as usual-Group (TAU)
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Sepsis, Prematurity
An Open Label Study to Describe the Pharmacokinetics of Cefazolin in Preterm Neonates
This is a phase I open label multi-dose study to investigative the pharmacokinetics and safety of cefazolin in infants <121 days of age and < 28 weeks gestation with suspected sepsis.
- Trial name
- NCT00850122
- Testing
- cefazolin
- Where
- Brazil
- Volunteers
- 9 people
- Sponsor
- Phillip Brian Smith
Apnea of Prematurity
CO2 Inhalation as a New Treatment Modality for Apnea of Prematurity
The objective of the present proposed study is to discover whether, in the nursery setting, administration of low concentration inhaled CO2 (0.8%) for a prolonged period (3 days) can make breathing more regular with less apneic…
- Trial name
- NCT01066728
- Testing
- CO2 inhalation, Theophylline
- Where
- 2 sites in Canada
- Volunteers
- 87 people
- Sponsor
- University of Manitoba
Premature Birth, Short Cervix
Prevention of Preterm Birth With a Pessary in Twin Gestations
Preterm birth (PTB) is a major health problem and contributes to more than 50% of the overall perinatal mortality. Twins are at increased risk for PTB.
- Trial name
- PoPPT (NCT02056639)
- Testing
- Bioteque cup pessary
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of Pennsylvania
Birth Asphyxia, Premature Birth
Oxygen Toxicity in the Resuscitation in Extremely Premature Infants
The investigators hypothesize that using low oxygen concentrations during resuscitation of extremely premature infants will avoid oxidative stress derived damage and improve outcome.
- Trial name
- OXTOX (NCT00494702)
- Testing
- Resuscitation
- Where
- Spain
- Volunteers
- 88 people
- Sponsor
- Fundacion Para La Investigacion Hospital La Fe
Premature Birth, Premature
Post-Care Positioning and Comfort in Late Preterm Infants
This study examined the comfort of late preterm infants (born at 34 0/7 to 36 6/7 weeks of gestation) placed in four positions after routine nursing care in a neonatal intensive care unit.
- Trial name
- NCT07881653
- Testing
- Sequential post-care positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Preterm Birth
Fetal Middle Cerebral Artery Doppler in Preterm Births Receiving Magnesium Sulfate for Neuroprotection
Two groups of women with preterm labor will be included. One will receive magnesium sulfate for neuroprotection and the other will receive placebo.
- Trial name
- NCT02506894
- Testing
- Magnesium Sulfate, 0.9% sodium chloride solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Prematurity, Delayed Passage of Meconium
Rectal Administration of Mother's Own Milk and Growth in Preterm Infants
This retrospective observational cohort study evaluated whether rectal administration of mother's own milk was associated with feeding progression and growth in preterm infants.
- Conditions
- Prematurity, Delayed Passage of Meconium, Feeding Intolerance
- Trial name
- NCT07908966
- Testing
- Rectal Administration of Mother's Own Milk
- Where
- Azerbaijan
- Volunteers
- 50 people
- Sponsor
- Azerbaijan Medical University
Prematurity
Reduction of Spontaneous Prematurity by Antibiotic Treatment (Josamycin)
The purpose of this study is to test the effectiveness of an antibiotic treatment (Josamycin) in the case of positive PCR for Ureaplasma spp. and/or Mycoplasma hominis in the second quarter on the risk of premature birth.
- Trial name
- PREMYC (NCT00718705)
- Testing
- Josamycin
- Where
- France
- Volunteers
- 3,200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preterm Birth, Apnea of Newborn
The Use of Wireless Sensors in Neonatal Intensive Care
The study will be conducted in a convenience sample of 75 infants admitted to the NICU at the Montreal Children's Hospital, divided into 3 phases: (a) Phase 1a - monitoring for 8h per day for 4 consecutive days, (b) Phase 1b …
- Trial name
- NCT04956354
- Testing
- ANNE™ Monitoring System (2 sensors) - version B, ANNE™ Monitoring System (2 sensors) - version C
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Third Stage of Labor
Homeopathic Remedy for the Third Stage of Delivery
The homeopathic remedy consisting of Arnica and Bellis perennis have been shown in a previous pilot study (n=33) to reduce blood loss during the third stage of delivery, when compared with placebo treatment.
- Trial name
- NCT01156194
- Testing
- Homeopathy 1, Homeopathy 2
- Where
- Israel
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Post Partum Hemorrhage
Mostafa Maged Maneuveur to Prevent and Control Post-partum Haemorrhage During Normal Vaginal Delivery
PPH is commonly defined as blood loss exceeding 1000 milliliters after vaginal birth or cesarean section.1 PPH is often classified as primary/immediate/early (occurring within 24 hours of birth) or secondary/delayed/late…
- Trial name
- NCT05288322
- Testing
- Mostafa Maged maneuver
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Fayoum University
Periodontitis, Premature Birth of Newborn
Feasibility and Acceptability of Use of Daily Oral Rinse in Pregnant Women in Rural Nepal
In Nepal, investigators are conducting a cohort study to estimate the relationship between signs of periodontal disease in pregnant women and preterm delivery.
- Trial name
- NCT02788786
- Testing
- Chlorhexidine, Cetylpyridinium chloride, Salt and Water
- Where
- Nepal
- Volunteers
- 175 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Breast Feeding, Infant, Premature
Breastfeeding Preterm Infants - The Efficacy of Internet-based Peer Support
This study examines if the internet-based peer support has an effect on the breastfeeding attitude or the duration of breastfeeding in preterm infants and their mothers compared with mothers with routine care.
- Trial name
- NCT02580786
- Testing
- Breastfeeding peer support
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Turku
Retinopathy of Prematurity (ROP)
Study on Effective Mydriasis in Premature Infants
The purpose of this study is to compare the dilating effect of 0, 1, 2 or 3 drops of mydriatic (pupil dilating) in premature infants undergoing routine retinal (eye) screening exams for Retinopathy of Prematurity (ROP).
- Trial name
- NCT01054027
- Testing
- 1% phenylephrine and 0.2% cyclopentolate
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Georgetown University
Premature (Early) Ejaculation, Ejaculatory Dysfunction
Extracorporeal Magnetic Innervation Plus Pelvic Floor Muscle Training for Premature Ejaculation
This single-center, prospective, parallel-group randomized controlled trial evaluated whether extracorporeal magnetic innervation (ExMI) added to pelvic floor muscle training (PFMT) improves pelvic floor muscle function and…
- Conditions
- Premature (Early) Ejaculation, Ejaculatory Dysfunction, Sexual Dysfunction Male
- Trial name
- NCT07385222
- Testing
- Pelvic Floor Muscle Training, Extracorporeal Magnetic Innervation
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Abant Izzet Baysal University
Placenta, Retained, Postpartum Hemorrhage
Optimisation of the Management of Placental Delivery in Second Trimester Pregnancy Interruption
Interruption of a pregnancy after 14 weeks gestation may be required when the fetus is dead, severely malformed or in cases of maternal illness.
- Trial name
- NCT00120042
- Testing
- Misoprostol, Oxytocin
- Where
- Australia
- Volunteers
- 251 people
- Sponsor
- The University of Western Australia
Premature Birth of Newborn
Improving Preterm Infant Outcomes With Family Integrated Care and Mobile Technology
The purpose of this study is to compare the standard of care in the neonatal intensive care unit (NICU), known as Family Centered Care, to a new model of care, called mobile enhanced Family Integrated Care.
- Trial name
- mFI-Care (NCT03418870)
- Testing
- Family Integrated Care
- Where
- 6 sites in United States
- Volunteers
- 347 people
- Sponsor
- University of California, San Francisco
Post Partum Hemorrhage
Evaluating Placental Thickness and Thickness of Uterine Muscle at Placenta Attachment in Prediction of Postpartum Blood Loss in Placenta Accreta
Aim of the Work is To determine the significance of the placental thickness and the thickness of the uterine muscle layer at placental attachment in the prediction of postpartum hemorrhage in cases of placenta previa accreta and…
- Trial name
- NCT06351969
- Where
- 2 sites in Egypt
- Volunteers
- 150 people
- Sponsor
- Benha University
Maternal Sepsis During Labor, Hemorrhage, Postpartum
Scaling Up an Integrated Approach to Improve Delivery Care in North Guatemala With Stepped Wedge Design
"¡Que Vivan las Madres!: Venga a tener su parto al CAP" (QVLM) is a guatemalan quasi-experimental study that has been performed from January 2014 to January 2017 by the Epidemiological Research Center in Sexual and Reproductive…
- Conditions
- Maternal Sepsis During Labor, Hemorrhage, Postpartum, Eclampsia; Complicating Pregnancy, Pre-Eclampsia
- Trial name
- QVLM (NCT03151070)
- Testing
- QVLM Intervention package
- Volunteers
- 32,000 people
- Sponsor
- Hospital San Juan de Dios Guatemala
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