Clinical trials: Labor and Delivery Complication
Pregnancy
17 Alfa Hydroxyprogesterone Caproate Versus Natural Progesterone for the Prevention of Preterm Labor
Preterm deliveries play a significant role in neonatal morbidity and mortality. Previous studies showed that administration of progesterone to pregnant women at high risk, decrease spontaneous preterm deliveries.
- Trial name
- NCT00809939
- Testing
- 17 alfa hydroxyprogesterone caproate, natural progesterone, vaginal progesterone
- Where
- Israel
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Preterm Birth, Pregnancy
Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)
Women pregnant with twins or triplets are at high risk of preterm birth, yet no intervention or approach has served to reduce this risk.
- Conditions
- Preterm Birth, Pregnancy, Multifetal
- Trial name
- NCT00099164
- Testing
- 17 alpha-hydroxyprogesterone caproate (17P)
- Where
- 14 sites in United States
- Volunteers
- 795 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Premature Birth
A Randomized Controlled Trial of Impact of Wearable, Wireless Breast Pumps on Frequency and Efficacy of Milk Expression in Mothers of Premature Infants
A randomized controlled trial of impact of wearable, wireless breast pumps on how often and how much milk mothers of premature infants can pump.
- Trial name
- MTMM (NCT06723067)
- Testing
- Wearable wireless breast pump
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Texas at Austin
Cervical Length, Preterm Birth
Development of a Screening Tool By Utilising Cervical Length Measurement In Relation To Body Mass Index (BMI) For Early Identification And Intervention Of Preterm Birth
This is a prospective study where pregnant women between 16-24 weeks gestation attending the Antenatal Clinic, Fetomaternal clinic or Obstetrics \& Gynaecology Admission Centre (OGAC) at Hospital Serdang or Hospital Pengajar UPM…
- Trial name
- NCT04922671
- Where
- 2 sites in Malaysia
- Volunteers
- 145 people
- Sponsor
- Universiti Putra Malaysia
Premature Infant, Chronic Respiratory Disease
Genesis Electrical Impedance Tomography (EIT): A Preliminary Study
The purpose of this study is to evaluate the Genesis Electrical Impedance Tomography (EIT) imaging system for use in pediatric respiratory disease populations including neuromuscular and bronchopulmonary dysplasia, as well as in…
- Conditions
- Premature Infant, Chronic Respiratory Disease, Neuromuscular Diseases, Healthy
- Trial name
- NCT03797183
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Macrosomia, Low Birth Weight
Wales Electronic Cohort for Children
The investigators are developing a research platform capable of improving children's health through the generation of knowledge from analysis of routinely collected data from within and outside the health service.
- Conditions
- Macrosomia, Low Birth Weight, Premature Birth, Childhood Obesity
- Trial name
- WECC (NCT01136681)
- Where
- 2 sites in United Kingdom
- Volunteers
- 900,000 people, healthy volunteers welcome
- Sponsor
- Swansea University
Premature Infants
Clinical Experience With Numeta in Preterm Infants
The aim of this prospective noninterventional study is to evaluate the clinical application of Numeta® in preterm infants and critically ill neonates in comparison to individualized prescribed parenteral nutrition.
- Trial name
- Numeta (NCT01981057)
- Testing
- Numeta, Individual
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Preterm Delivery
Lactoferrin or Progesterone for Prevention of Preterm Delivery
Primary endpoint will be evaluate the effectiveness of vaginal lactoferrin in the reduction of the 30% of preterm deliveries versus the use of progesterone, in specific selected patients, with consequent improvement in neonatal…
- Trial name
- NCT02372942
- Testing
- Lattoferrin, Progesterone
- Where
- Italy
- Volunteers
- 1,030 people
- Sponsor
- University of Padova
Postpartum Hemorrhage, Uterine Atony
Exteriorization Versus In Situ Hysterotomy Repair During Cesarean: Effects on Uterine Tone
During standard cesarean deliveries, there are two ways that obstetricians repair the incision on the uterus (hysterotomy after delivery of the baby.
- Conditions
- Postpartum Hemorrhage, Uterine Atony, Uterine Atony With Hemorrhage, Cesarean Section
- Trial name
- NCT07606846
- Testing
- Test Intervention: In Situ Repair, Comparator Intervention: Exteriorization
- Volunteers
- 60 people
- Sponsor
- Stanford University
Premature Birth, Psychological Stress
Parental Stress and Attachment in Preterm Infants
Introduction: Advances in neonatology mean a significant reduction in mortality in premature infants as well as an increase in the risk of morbidity in the medium, short and long term.
- Conditions
- Premature Birth, Psychological Stress, Physiological Stress
- Trial name
- NCT06813560
- Testing
- hair cortisol, salivary cortisol, salivary Oxytocin
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Prematurity; Extreme
Pulmonary Vascular Disease and Cardiac Performance in Extreme Preterm Infants
Pulmonary vascular disease and cardiac performance in extreme preterm infants: A prospective cross-sectional study
- Trial name
- NCT04114435
- Testing
- Echocardiography
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Endotracheal Aspiration
Effect of Touch Methods in Preterm Infants During Endotracheal Aspiration
The purpose of this study was to determine the effect of gentle human touch (GHT) and Yakson methods during endotracheal suctioning on pain, comfort and physiologic parameters response in preterm infants.
- Trial name
- NCT06308991
- Testing
- Yakson touch, Gentle Human Touch, Routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Democracy University
Infant, Very Low Birth Weight
Evaluation of Prolact-Plus Human Milk Fortifier
Prolacta Bioscience has developed the first purely human fortifier, Prolact-Plus, that can provide a source of many of the required nutrients for premature, newborn infants, particularly protein and calories.
- Trial name
- NCT00486590
- Testing
- Prolact-Plus Human Milk Fortifier
- Where
- 4 sites in United States
- Volunteers
- 105 people
- Sponsor
- Prolacta Bioscience
Malaria, Sexually Transmitted Diseases
Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth
The purpose of this study is to examine whether treatment of pregnant Malawian women with repeated doses of sulfadoxine-pyrimethamine and azithromycin antibiotics will prevent preterm deliveries and result in other health…
- Conditions
- Malaria, Sexually Transmitted Diseases, Preterm Birth, Pregnancy
- Trial name
- NCT00131235
- Testing
- Sulfadoxine-pyrimethamine treatment twice during pregnancy, Sulfadoxine-pyrimethamine at 4-week intervals, Sulfadoxine-pyrimethamine every 4 weeks + azithromycin twice
- Where
- Malawi
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- Tampere University
Body Composition, Beneficial
Impact of Exercise on Body Composition in Premature Infants
This research consists of a novel intervention designed to increase physical activity of premature babies in their first year of life. The potential beneficial impact of augmented physical activity on: 1. Body composition 2.
- Trial name
- NCT01386190
- Testing
- Exercise/Social Behavioral
- Where
- United States
- Sponsor
- University of California, Irvine
Induced; Birth
The REDUCED-I Pilot Trial: REDucing the Utilization of CEsarean Sections With Induction
This pilot project is a randomized controlled trial where induced patients receive an intervention of oxytocin discontinuation once in the active stage of labor (≥6 cm dilation).
- Trial name
- (REDUCED-I) (NCT05037617)
- Testing
- Continuation or discontinuation of oxytocin during the active first stage of labor (≥6 cm dilation).
- Where
- Canada
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Premature Birth
A Cluster Randomized Controlled Trial of FICare At 18 Months
In Alberta, one in every twelve babies is born preterm. Compared with their full term counterparts, preterm infants who survive are at higher risk for respiratory problems, jaundice, infections, feeding problems, behavioural…
- Trial name
- NCT03337659
- Testing
- Family Integrated Care
- Where
- Canada
- Volunteers
- 297 people
- Sponsor
- University of Calgary
Preterm
Bovine Colostrum in Prevention of Sepsis and Retinopathy of Prematurity
The aim of this study is to evaluate efficacy of bovine colostrum administration as a prophylaxis to decrease the incidence and the occurrence of retinopathy of prematurity in preterm neonates of gestational age less than 32…
- Trial name
- NCT05438680
- Testing
- The bovine colostrum ( trade name : baby steps sachets, 300mg )
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Alexandria University
Preterm Birth
Universal Transvaginal Cervical Length Screening Program for Prevention of Preterm Birth in Singletons Without Prior Preterm Birth
This is a non-blinded randomized screening trial of asymptomatic singleton pregnancies without prior spontaneous preterm birth who are randomized to either transvaginal ultrasound cervical length screening program (i.e.
- Trial name
- NCT03591042
- Testing
- cervical length screening
- Where
- 2 sites in Italy
- Volunteers
- 1,334 people
- Sponsor
- Federico II University
Bronchopulmonary Dysplasia (BPD), Prematurity
Oral Vitamin A Supplementation for Prevention of Bronchopulmonary Dysplasia in Preterm Infants
Bronchopulmonary dysplasia (BPD) remains a major complication of very low birth weight (VLBW) preterm infants. Vitamin A is essential for lung development and epithelial integrity, and deficiency has been associated with an…
- Conditions
- Bronchopulmonary Dysplasia (BPD), Prematurity, Very Low Birth Weight
- Trial name
- VITA-BPD (NCT07577180)
- Testing
- Vitamin A
- Where
- Turkey (Türkiye)
- Volunteers
- 209 people
- Sponsor
- Erhan Calisici
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