Clinical trials: Labour Analgesia
Analgesia, Epidural
Levobupivacaine for Epidural Analgesia in Labour
In a prospective randomised study involving primiparous women in spontaneous uncomplicated labour with cervical dilatation > 7 cm, epidural analgesia will be given with an initial volume of 20 mL anaesthetic solution, followed by…
- Trial name
- NCT00929682
- Testing
- Randomization between two referenced treatments
- Volunteers
- 136 people
- Sponsor
- University Hospital, Clermont-Ferrand
Labor Pain
Virtual Reality Analgesia in Labor: The VRAIL Pilot Study
The purpose of the proposed study is to evaluate the feasibility of using immersive Virtual Reality (VR) during labor. We will also explore whether VR distraction is helpful for reducing subjective pain during labor, even if this…
- Trial name
- VRAIL (NCT02926469)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Epidural Anesthesia in Labor and Delivery
Pocket Warming of Epidural Medication
This study will examine recent claims regarding the beneficial effect of warming epidural medications in order to hasten the onset of labor analgesia.
- Trial name
- NCT02912078
- Testing
- Pocket-warming, Standard of Care Labor Epidural
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Ohio State University
Cervical Dilatation, Bishop Score
the Effects of Epidural Fentanyl on Vaginal Delivery
The study hypothesis was that epidural fentanyl may accelerate the dilation of the cervix and possibly result in a shorter duration of vaginal delivery.
- Conditions
- Cervical Dilatation, Bishop Score, Duration of Delivery
- Trial name
- EFVD (NCT02135224)
- Testing
- Fentanyl, Normal saline
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Athens
Labor Analgesia
Patient Education on Labor Analgesia Options
The purpose of this study is to learn how the investigators can better educate pregnant patients about the options open to them for pain relief during labor.
- Trial name
- NCT02557555
- Testing
- educational information
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Quality Health Care
Dural Puncture Epidural Vs Standard Epidural Technique in Parturient Receiving Continuous Labour Epidural Infusion
The goal of this study is to evaluate the quality and safety of labor analgesia by comparing the use of Dural puncture epidural technique to Standard epidural technique while maintaining labor analgesia by means of continuous…
- Trial name
- NCT06653036
- Testing
- Dural puncture epidural, Standard Epidural Technique
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Obstetric Pain, Other Complications of Obstetric Anesthesia - Delivered
Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome
To assess the efficacy of epidural dexamethasone administration, compared to placebo, in reducing local anesthetics consumption during labor epidural analgesia in parturient women
- Trial name
- DEXAPER (NCT02857465)
- Testing
- Dexamethasone, Ropivacaine, Sufentanil
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Labor Pain, Post-cesarean Delivery
Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia
Pharmacogenetics has allowed clinicians to identify associations between an individual's genetic profile and his/her response to drugs.
- Trial name
- NCT00418015
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Labor Pain, Analgesia
Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques
To estimate the dose of bupivacaine required to achieve initial effective comfort in 90% of patients (ED90) via the epidural (DPE or EPL) technique in women undergoing labor.
- Trial name
- NCT04814537
- Testing
- Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Analgesia, Labor Analgesia
A Clinical Study on the Effect of Labor Analgesia on the Postpartum Recovery Outcome of Chinese Parturients
Background: The parturient will experience extreme pain during delivery. Effective labor analgesia will bring better delivery experience to the parturient, while the adverse experience during delivery may bring many adverse…
- Trial name
- NCT05666024
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Pain Relief in Labour
A Randomised Controlled Trial of Remifentanil Intravenous Patient Controlled Analgesia (PCA) Versus Intramuscular Pethidine for Pain Relief in Labour
Childbirth can be an extremely painful and the provision of pain relief during labour is a vital component of a positive maternal experience.
- Trial name
- RESPITE (NCT02179294)
- Testing
- Pethidine, Remifentanil
- Where
- United Kingdom
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Labor Pain, Analgesia
ED90 of Epidural Bupivacaine With Lidocaine for the Initiation of Labor Analgesia
To estimate the dose of bupivacaine required to achieve initial effective comfort in 90% of patients (ED90) via the epidural (DPE or EPL) technique in women undergoing labor after receiving a lidocaine "test dose"
- Trial name
- NCT05543694
- Testing
- Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pain
Preventive Analgesia in Multiparas Undergoing Induction of Labour
Our study is about providing a better birthing experience by placing and initiating epidural for labour pain before the contractions start.
- Trial name
- NCT00465231
- Testing
- bupivacaine, fentanyl, preservative free saline
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Pain
The Effect of Music Therapy on Labour Pain, Anxiety, and Analgesia
Labour pain is the result of complex and subjective interactions of multiple physiologic and psychosocial factors on a woman's interpretation of labour stimuli.
- Trial name
- NCT05149677
- Testing
- Music therapy
- Where
- Jamaica
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Analgesia
Comparison of Patients' Postpartum Recovery Using ObsQoR-10 Score in Pregnant Women in Vaginal Delivery With and Without Neuraxial Labor Analgesia
The aim of this study was to compare the postpartum recovery of pregnant women who had vaginal delivery with and without neuraxial labor analgesia using the ObsQoR-10 scoring system.
- Trial name
- NCT06325475
- Testing
- labor with neuraxial labor analgesia, labour without noroaxial labor analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Labor Pain, Epidural
A Comparison Between 2 Methods of Local Anesthetic Administration for Maintaining Labor Analgesia After Dural Puncture Epidural
Intermittent epidural bolus technique opens a new era of interest for maintaining labor anlagesia. The study examines programmed intermittent epidural bolus technique on a scheduled basis to provider-administered bolus anlgesia…
- Conditions
- Labor Pain, Epidural, Pain, Labor
- Trial name
- NCT05034211
- Testing
- Programmed intermittent bolus epidural, Provider administered analgesia on patient request
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aretaieio Hospital
Labor Analgesia, Prolonged
Effects of Ropivacaine Concentrations on Prolonged Labor Analgesia
With the changes in medical models and improvements in people's quality of life, parturients have higher demands for childbirth, making the alleviation and elimination of labor pain an important aspect of modern obstetrics.
- Conditions
- Labor Analgesia, Prolonged, Ropivacaine, Concentration
- Trial name
- NCT07007650
- Testing
- High-concentration Ropivacaine, Low concentration ropivacaine group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Effects of Anesthesia Spinal and Epidural in Pregnancy
Air Versus Saline Solution for the Localization of the Epidural Space in Labour Analgesia
Epidural space localization using loss of resistance technique with air (ALOR) is controversial in obstetric analgesia due to a minor efficacy and risk of complications, compared with loss of resistance technique with saline…
- Trial name
- NCT02792933
- Testing
- air in epidural space, saline in epidural space
- Volunteers
- 400 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Pregnancy, Labor Pain
Epidural Volume Extension During a Combined Spinal-Epidural Technique for Labor Analgesia.
Combined spinal-epidurals (CSE) involve the injection of pain relief medication into the cerebral spinal fluid (CSF) and the insertion of an epidural catheter in the epidural space to continue to give pain relief medication.
- Trial name
- NCT01810406
- Testing
- CSE with 10 ml EVE, CSE without EVE
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- IWK Health Centre
Pregnancy
Nitrous Oxide and Neuraxial Labor Analgesia Use on Maternal Fetal Outcomes
The purpose of this study is to evaluate maternal and neonatal outcomes in parturients who used nitrous oxide and neuraxial labor analgesia during labor.
- Trial name
- NOLA (NCT04813874)
- Testing
- Nitrous Oxide, Neuraxial analgesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital