Clinical trials: Laceration Repair
Rotator Cuff Tear
Liposomal Bupivacaine After Arthroscopic Rotator Cuff Repair
Liposomal bupivacaine, a long-acting form of bupivacaine, has been found to be effective for postoperative pain control after total knee, total hip and total shoulder arthroplasty.
- Trial name
- NCT03149887
- Testing
- Liposomal bupivacaine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Steven Orebaugh
Tibial Meniscus Injuries, Tibial Meniscus Tears
Success of Long-acting Anti-inflammatories After Anterior Cruciate Ligament and Meniscal Injury
The purpose of this study is to determine if extended-release triamcinolone acetonide treatment alters the progressive changes in bone shape previously demonstrated after anterior cruciate ligament (ACL) reconstruction with…
- Conditions
- Tibial Meniscus Injuries, Tibial Meniscus Tears, Tibial Meniscus, Torn, Anterior Cruciate Ligament Tear
- Trial name
- SLAM (NCT04331002)
- Testing
- Zilretta
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Austin V Stone
Rotator Cuff Tear
Types of Fixation in Arthroscopic Rotator Cuff Repair
The study will identify if there is a difference of quality of life after surgery between two techniques used in surgery. The two different techniques are either the Single Row Fixation or the Double Row Fixation.
- Trial name
- NCT00508183
- Testing
- single row, double row fixation
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Rotator Cuff Tear Arthropathy
Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder Functional Outcomes
This will be a randomized controlled trial to determine if postoperative ibuprofen after arthroscopic rotator cuff repair impacts postoperative opiate medication use, Visual Analog Scale (VAS) pain scores, shoulder range of…
- Trial name
- NCT02588027
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, San Francisco
Wounds and Injuries, Lacerations
A Clinical Study to Compare MAR-CUTIS With Dermabond Advanced
This was a randomized, open-label, multicenter, comparator-controlled clinical study to compare MAR-CUTIS with Dermabond Advanced in closure of surgical incisions and lacerations less than or equal to (<=)15 centimeter (cm).
- Conditions
- Wounds and Injuries, Lacerations, Surgical Incision
- Trial name
- NCT03688880
- Testing
- MAR-CUTIS, Dermabond Advanced
- Where
- 19 sites in France, Germany and 2 more
- Volunteers
- 107 people
- Sponsor
- Grünenthal GmbH
Bankart Lesions, SLAP Lesion
PMCF Study on the Safety, Performance and Clinical Benefits Data of the ToggleLoc™ 2.9mm and JuggerLoc™ in the Shoulder
The study is a multicenter, retrospective, non-randomized, non-controlled and consecutive series post-market study. The purpose of this study is to collect data confirming safety, performance and clinical benefits of the…
- Conditions
- Bankart Lesions, SLAP Lesion, Acromioclavicular; Dislocation, Capsular Shift/Capsulolabral Reconstruction
- Trial name
- NCT05584553
- Testing
- ToggleLoc 2.9 mm soft tissue device, JuggerLoc soft tissue device
- Where
- 3 sites in United States, Spain
- Volunteers
- 214 people
- Sponsor
- Zimmer Biomet
Rotator Cuff Tear, Postoperative Pain
Oral Ketorolac for Arthroscopic Rotator Cuff Repair
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following arthroscopic rotator cuff repair. 2.
- Trial name
- NCT03967847
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University Hospitals Cleveland Medical Center
Procedural Anxiety
Dose-Finding Study of Intranasal Midazolam for Procedural Sedation in Children
Dose-finding study to compare intranasal midazolam doses of 0.2, 0.3, 0.4 and 0.5 mg/kg in children undergoing laceration repair to achieve the following aims: Specific Aim #1: To determine the most effective dose of intranasal…
- Trial name
- NCT04586504
- Testing
- Intranasal midazolam
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Columbia University
Rotator Cuff Tear
Nonopioid Analgesia After Rotator Cuff Repair
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of rotator cuff repair: a treatment group given a…
- Trial name
- NCT03818919
- Testing
- Celecoxib, Ketorolac, Gabapentin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Laceration of Hand, Laceration of Forearm
Suture Repair of Lacerations in the ED: Comparison Between Two Suture Materials
This study aims to determine whether the use of non-absorbable (i.e. nylon) versus absorbable (i.e. chromic gut) sutures in traumatic hand lacerations affects wound healing, patient perception, and development of complications.
- Trial name
- NCT05281666
- Testing
- Absorbable Surgical Gut Suture material, Non-absorbable Nylon Suture Material
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Kenneth Taylor, M.D.
Meniscus Tear, Tibial, Meniscus Lesion
JuggerStitch Post Market Clinical Follow-up Study
This study is a post-market follow-up study. The data collected from this study will serve the purpose of confirming the safety and performance of the JuggerStitch Device used for meniscal repair according to the product…
- Trial name
- NCT04228367
- Testing
- JuggerStitch Meniscal Repair Device
- Where
- 6 sites in United States, France and 2 more
- Volunteers
- 103 people
- Sponsor
- Zimmer Biomet
Meniscus Disorder, Meniscus, Torn Tibial
Blood Flow Restriction After Meniscus Repair
The purpose of this study is to evaluate post-operative outcomes after meniscus surgery in participants undergoing blood flow restriction training as a rehabilitative adjunct compared to those with standard rehabilitation.
- Conditions
- Meniscus Disorder, Meniscus, Torn Tibial, Meniscus Lesion, Meniscus Tear, Tibial
- Trial name
- NCT04436523
- Testing
- Blood flow restriction (Delfi Personalized Tourniquet System), Standard rehabilitation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Full Thickness Rotator Cuff Tear
Mesenchymal Stem Cell Augmentation in Patients Undergoing Arthroscopic Rotator Cuff Repair
The primary objective of this study is to compare the clinical outcomes of arthroscopic rotator cuff repair with and without augmentation of mesenchymal stem cells (MSCs).
- Trial name
- NCT02484950
- Testing
- Mesenchymal stem cell augmentation in rotator cuff repair, Standard arthroscopic rotator cuff repair
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Rush University Medical Center
Meniscus Tear, Knee Meniscus Injury
High-Purity Type I Collagen Augmentation in Meniscal Repair
This prospective, single-arm feasibility study evaluates the safety, procedural feasibility, and early clinical outcomes of High-Purity Type I Collagen used as an adjunct in arthroscopic meniscal repair.
- Conditions
- Meniscus Tear, Knee Meniscus Injury, Meniscal Repair, Knee Arthroscopy (for Diagnostic or Therapy)
- Trial name
- NCT07352410
- Testing
- High-Purity Type I Collagen
- Where
- India
- Volunteers
- 18 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Laceration, Anxiety
Intranasal Dexmedetomidine vs Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair
The objective of this research study is to show superiority of intranasal dexmedetomidine to intranasal midazolam as anxiolysis prior to pediatric laceration repairs.
- Trial name
- NCT02168439
- Testing
- Dexmedetomidine, Midazolam
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Vaginal Laceration During Delivery
The PAIN (Pelvic Area Injection for Numbness) Study
Postpartum pain can interfere with patient's ability to care for themselves, and their newborn, and untreated pain is associated with risk of greater opioid use, postpartum depression, and development of persistent pain.
- Trial name
- PAIN (NCT05972681)
- Testing
- Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Anxiety, Laceration Repair
iPad as a Distraction Tool During Facial Laceration Repair
Children aged 2-12 presenting to the Rady Children's Hospital San Diego (RCHSD) emergency department with facial lacerations requiring suture repair will be eligible to participate in the study.
- Conditions
- Anxiety, Laceration Repair, Children
- Trial name
- NCT02217436
- Testing
- iPad, Standard Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Laceration Repair, Children, Hand Injuries
Cosmetic Outcome at 4 Months in Hand and Feet Lacerations in Children: Conservative Versus Suture Repair
Hand and feet lacerations are common in children with repair often requiring conscious sedation and needle sticks for repair. Growing evidence in adults reveal that many of these small lacerations do quite well cosmetically…
- Conditions
- Laceration Repair, Children, Hand Injuries, Foot Injuries
- Trial name
- NCT03321721
- Testing
- Suture for wound repair
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- St. Louis University
Bankart Lesion, Acetabular Labrum Tear
S&P of Q-Fix™ All-Suture Anchor System
Post-market clinical follow-up needed to address existing clinical data and gaps on the existing Q-Fix™ device and meet existing MDD/MEDDEV requirements
- Conditions
- Bankart Lesion, Acetabular Labrum Tear, SLAP Lesion, Acromioclavicular Sprain
- Trial name
- NCT03594071
- Testing
- The Q-Fix™ All-Suture Anchor
- Where
- 5 sites in United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Smith & Nephew, Inc.
Lacerations, Pain, Procedural
Comparison of Two Application Techniques for LET Gel
Comparison of anesthetic efficacy of Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel (LET) applied three times for 10 minutes each time vs.
- Conditions
- Lacerations, Pain, Procedural, LET
- Trial name
- NCT04203225
- Testing
- LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center