Clinical trials: Lacunar Stroke
Stroke, Ischemic, Stroke, Acute
Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients
This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke, Lacunar, Hemiparesis
- Trial name
- NCT04770363
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Cerebral Small Vessel Diseases, Inflammation
INflammation and Small Vessel Disease Study
A prospective observational cohort study in patients with cerebral small vessel disease deterring whether changes in systemic inflammation predict brain white matter damage measured using MRI and cognitive decline.
- Conditions
- Cerebral Small Vessel Diseases, Inflammation, Stroke
- Trial name
- INSVD (NCT05746221)
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Cambridge
Ischemic Stroke, Cerebral Infarction
Detection of Silent Atrial Fibrillation aFter Ischemic StrOke
The primary objective of this study is to evaluate whether, in patients with first-ever atherothrombotic or lacunar stroke without any previous history of atrial fibrillation (AF)/atrial flutter (AFL)/atrial tachycardia (AT), the…
- Conditions
- Ischemic Stroke, Cerebral Infarction, Brain Ischemia, Brain Infarction
- Trial name
- SAFFO (NCT02684825)
- Testing
- Reveal LINQTM- LNQ11 Internal Loop Recorder plus standard cardiac monitoring
- Where
- Italy
- Volunteers
- 317 people
- Sponsor
- Danilo Toni
Cerebral Small Vessel Diseases, Lacunar Stroke
Retinal Vessel Leakage in Cerebral Small Vessel Disease
The goal of this observational study is to learn about leakage from retinal vessels in cerebral small vessel disease. The main questions it aims to answer are: Does retinal vessel leakage occur in cerebral small vessel disease?…
- Conditions
- Cerebral Small Vessel Diseases, Lacunar Stroke, Vascular Dementia
- Trial name
- NCT06416371
- Testing
- Fundus fluorescein angiography, with ultrawide field retinal imaging
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Acute Ischemic Stroke
CompARing Between CO2 Phenylephrine and Phenylephrine Only Treatment in Patients With proGrEssing Cerebral infarctioN
Progressing stroke is associated poor functional outcome and neurological deficit. Currently, no treatment for progressing stroke is recommended on the guideline. Carbogen is a mixture of 5% CO2 with 95% O2.
- Trial name
- NCT06770426
- Testing
- carbogen with or without phenyleprhine, phenylephrine
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Cerebral Small Vessel Diseases, Cognitive Impairment
Lacunar Intervention Trial 1 (LACI-1)
Phase II pilot randomised, factorial, short term dose escalation, open label, blinded intermediary endpoint trial, in two hospital centres in the UK, of tolerability and safety of cilostazol, isosorbide mononitrate, both or…
- Conditions
- Cerebral Small Vessel Diseases, Cognitive Impairment, Stroke
- Trial name
- Prevent-SVD (NCT02481323)
- Testing
- isosorbide mononitrate, cilostazol
- Where
- 2 sites in United Kingdom
- Volunteers
- 57 people
- Sponsor
- University of Edinburgh
Stroke, Lacunar
Effect of Remote Ischemic Conditioning on Vascular Health in Stroke Patients
The main aim of the current study is to assess cardiovascular effects of remote ischemic conditioning in patients who have suffered from stroke.
- Trial name
- VISP (NCT03635177)
- Testing
- Remote ischemic conditioning
- Where
- 2 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- University of Copenhagen
Acute Ischemic Stroke
Comparing Between CO2 and Phenylephrine Treatment in Patients With Progressive Lacunar Infarction (CARBOGEN Study)
Lacunar infarction is an ischemic stroke occurred by small perforating artery occlusion . Twenty percent of ischemic stroke is lacunar infarction.
- Trial name
- NCT04839224
- Testing
- carbogen, phenylephrine
- Where
- South Korea
- Volunteers
- 3 people
- Sponsor
- Yonsei University
Cerebral Small Vessel Disease, Stroke
Cerebral Small Vessel Disease Progression Dependent on Stroke Type
The goal of this prospective, observational study is to understand if cerebral small vessel disease (CSVD) has different velocities and patterns of temporal development, dependent on a concurrent ischemic stroke.
- Conditions
- Cerebral Small Vessel Disease, Stroke, Stroke Recurrence, Biomarkers
- Trial name
- ZMA_BIO (NCT07611136)
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Johannes Dorst