Clinical trials: Laminectomy, open to volunteers
Lumbar Decompression
MRI Outcomes of VersaWrap Nerve Protector Following Surgery
The purpose of this study is to evaluate enhancement patterns in magnetic resonance imaging (MRI) evidence following the use of VersaWrap in bilateral lumbar decompression surgeries.
- Trial name
- NCT06942819
- Testing
- VersaWrap Nerve Protector
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Research Source
Spinal Cord Injury, Acute Spinal Cord Injury (SCI)
Guided Laminectomy With Augmented Duroplasty for Acute Traumatic Spinal Cord Injury
The goal of this clinical trial is to learn whether expansile duraplasty can improve neurological recovery in adult patients with acute severe traumatic spinal cord injury, as well as evaluate the safety of this surgical…
- Trial name
- GLAD (NCT07733401)
- Testing
- Expansile duraplasty
- Where
- 13 sites in China
- Volunteers
- 80 people
- Sponsor
- Xuanwu Hospital, Beijing
Cervical Stenosis, Degenerative Cervical Spinal Stenosis
Laminoplasty Versus Laminectomy With Lateral Mass Fixation in Management of Degenerative Cervical Canal Stenosis
Cervical canal stenosis (CCS) is a condition characterized by the narrowing of the spinal canal in the cervical spine, leading to compression of the spinal cord and nerve roots.
- Trial name
- NCT07177651
- Testing
- Laminoplasty, Laminectomy with lateral mass fixation
- Volunteers
- 2 people
- Sponsor
- Assiut University
LUMBAR STENOSIS, Sagittal Imbalance
Spontaneous Correction of Sagittal Imbalance After Isolated Lumbar Decompression
Sagittal spinal imbalance may be caused by orthopedic problems, compression of the neural structures of the spinal canal, and pain syndrome (functional imbalance).
- Conditions
- LUMBAR STENOSIS, Sagittal Imbalance, Degeneration Lumbar Spine, Lumbar Decompression
- Trial name
- NCT07139938
- Testing
- Isolated lumbar decomression
- Where
- 3 sites in Russia
- Volunteers
- 165 people
- Sponsor
- N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
PONV, Cerebellopontine Angle Tumor
Oliceridine Versus Sufentanil for Postoperative Nausea in Cerebellopontine Angle Surgery
This single-center, double-blind, randomized controlled trial aims to determine whether oliceridine for patient-controlled intravenous analgesia (PCIA) can significantly reduce the incidence of postoperative nausea, an…
- Conditions
- PONV, Cerebellopontine Angle Tumor, Microvascular Decompression Surgery, Postoperative Analgesia
- Trial name
- NCT07479446
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Xuanwu Hospital, Beijing
Cervical Disc Prolapse
Functional Outcome After Combined Posterior Laminectomy and Anterior Cervical Discectomy and Fusion for Large Cervical Disc Prolapse
Cervical disc herniation (CDH) is the result of the displacement of the nucleus pulposus of the intervertebral disc, which may result in impingement of the traversing nerves as they exit the neural foramen or directly compressing…
- Trial name
- NCT06847503
- Volunteers
- 25 people
- Sponsor
- Assiut University
Pain, Disability
Additional Effects of Pain Neuroscience Education With Standard Pre-operative Physiotherapy on Post-laminectomy Pain and Disability.
This randomized controlled trial investigates whether adding Pain Neuroscience Education (PNE) to standard pre-operative physiotherapy improves outcomes after lumbar laminectomy.
- Conditions
- Pain, Disability, Laminectomy, Physical Therapy
- Trial name
- NCT07801586
- Testing
- Experimental Group - Pain Neuroscience Education + Standard Pre-operative Protocol, Control Group - Standard Pre-Operative Care
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Spinal Fusion, Chronic Lower Back Pain
Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery
After spinal fusion and decompression surgery there is a possible risk of developing chronic back pain. After surgery there is typically inflammation around the operation site and this inflammation can be painful and debilitating…
- Trial name
- NCT06282770
- Testing
- Laser Diode Brace
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Trigeminal Neuralgia, Microvascular Decompression Surgery
Post-Operative Trigeminal Pain After Microvascular Decompression for Trigeminal Neuralgia
The goal of this observational study is to learn about the long-term effects of microvascular decompression (MVD) in patients with trigeminal neuralgia (TN).
- Conditions
- Trigeminal Neuralgia, Microvascular Decompression Surgery, Post-operative Pain
- Trial name
- NCT07216547
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons
Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover
Chronic back pain is the world's leading cause of disability, with spine surgery being a common yet costly intervention. However, many patients experience suboptimal recovery, with persistent pain and functional limitations…
- Conditions
- Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons, Chronic Low Back Pain, Scoliosis Patients
- Trial name
- NCT07766824
- Testing
- Ready Set Recover
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National University of Natural Medicine
Spinal Surgery for Lumbar Spinal Stenosis (LSS)
Activity Post Spinal Surgery Engagement Trial
Back pain can be disabling, limiting the ability to walk and to engage in physical activity. For patients with degenerative lumbar spinal stenosis, decompressive surgery often provides substantial pain relief and improved…
- Trial name
- ASSET (NCT07825480)
- Testing
- Wrist based activity tracker wear, Basic Study Activities, Telephonic Active Coaching (Motivational Interviewing) + Financial Incentives
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Brigham and Women's Hospital
Spine Surgery, Telerehabilitation
Telerehabilitation After Spine Surgery
The goal of this randomized clinical trial is to assess how different methods of delivering post-operative instructions affect the participants' recovery after spinal decompression surgery.
- Conditions
- Spine Surgery, Telerehabilitation, Low Back Pain
- Trial name
- NCT07795697
- Testing
- Telerehabilitation method, Nurse instructions, Physiotherapy after surgery, personal
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Kuopio University Hospital
Lumbar Spinal Stenosis
Decompressive Laminectomy Versus Laminectomy With Transpedicular Fixation in Lumbar Spinal Stenosis
Lumbar spinal stenosis is a condition where the spinal canal becomes narrowed and can cause symptoms such as back pain, numbness, leg pain, and difficulty walking.
- Trial name
- NCT07281625
- Testing
- Decompressive Laminectomy, Decompressive Laminectomy With Transpedicular Screw Fixation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Punjab Health Care Commission
Sacral Fractures, Traumatic Unstable Sacral Fractures
Open Versus Minimally Invasive Fixation for Unstable Sacral Fractures in Adults
Severe injuries to the lower spine and pelvis, known as traumatic unstable sacral fractures, are complex injuries that often require surgery to stabilize the bones and prevent long-term disability.
- Conditions
- Sacral Fractures, Traumatic Unstable Sacral Fractures, Spinopelvic Dissociation, Pelvic Ring Injuries
- Trial name
- NCT07534579
- Volunteers
- 60 people
- Sponsor
- Assiut University
Lumbar Spinal Stenosis, Spinal Stenosis
Necessity of Fusion Following Decompression Surgery in Patients With Single-level Lumbar Stenosis
Long-term clinical results of two methods of surgical treatment (spinal decompression with or without fusion) in patients with single-level lumbar stenosis will be compared.
- Conditions
- Lumbar Spinal Stenosis, Spinal Stenosis, Spinal Fusion
- Trial name
- NCT05273879
- Testing
- decompression, fusion
- Where
- 2 sites in Russia
- Volunteers
- 86 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Spinal Metastases
Intraoperative Radiotherapy in Treating Spinal Metastases
In order to provide theoretical evidence for the comprehensive and standardized treatment of spinal metastases with pathological fractures and/or spinal cord compression, the investigators conduct this trial to investigate the…
- Trial name
- NCT06093854
- Testing
- Intraoperative radiotherapy (IORT), Stereotactic body radiotherapy (SBRT)
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Shanghai Changzheng Hospital
Chronic Pain, Chronic Pain Due to Injury
Virtual Pain Education for Spinal Cord Stimulation Patients
Chronic pain is a leading cause of disability in the United States. When standard treatments fail, many patients develop treatment resistant pain and undergo Spinal Cord Stimulation (SCS) therapy.
- Conditions
- Chronic Pain, Chronic Pain Due to Injury, Failed Back Syndrome, Persistent Spinal Pain Syndrome
- Trial name
- SCS-PNE (NCT07743905)
- Testing
- SCS-PNE intervention
- Volunteers
- 50 people
- Sponsor
- University of Arkansas
Laminectomy, Intraocular Pressure
Measurement of Intraocular Pressure in Patients Undergoing Laminectomy in the Prone Position
Laminectomy surgeries, typically performed for lumbar disc herniation and spinal disorders, are often lengthy surgical procedures requiring patients to be in the prone position.
- Conditions
- Laminectomy, Intraocular Pressure, Prone Position
- Trial name
- NCT07067008
- Volunteers
- 60 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Lumbar Canal Stenosis, Lumbar Spinal Stenosis
Is it Really Necessary Going All Over the Top in Patients With Symptomatic Lumbar Spinal Stenosis?
The goal of this clinical trial is to evaluate the theory of epidural pressure by comparing a surgical procedure that aims to perform less bone resection compared to conventional surgery in patients with lumbar spinal stenosis.
- Conditions
- Lumbar Canal Stenosis, Lumbar Spinal Stenosis, Lumbar Spinal Stenosis (LSS)
- Trial name
- NCT07026305
- Testing
- Pressure-guided laminectomy (PGL), Laminectomy without pressure guidance (LWPG)
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidad Complutense de Madrid
Foraminal Stenosis
Comparative Outcomes of Conventional TLIF With Posterior Decompression Surgery Versus Endoscopic Foraminotomy Surgery
Comparative Outcomes of Conventional Transforaminal Lumbar Interbody Fusion With Posterior Decompression Surgery Versus Endoscopic Foraminotomy Surgery in Stable Lumbar Foraminal Stenosis An Ambi-directional Cohort Study
- Trial name
- TLIF (NCT06685575)
- Testing
- Endoscopic Foraminotomy Surgery
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand