Clinical trials: Language Development Disorders, open to volunteers
Developmental Language Disorder
Exercise Training in Children With Communication Impairments
This clinical trial study has two goals. The first goal is to establish fitness levels, participation in physical activities, and fine/gross motor abilities for children with development language disorder (DLD).
- Trial name
- NCT06340893
- Testing
- Exercise, Restful Play
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marquette University
Central Auditory Processing Disorder, Hearing Impaired (Partially)
A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound
The goal of this clinical trial is to determine the efficacy of Clemastine Fumarate in the presence of engineered sound to treat age-related central auditory processing disorder (CAPD).
- Conditions
- Central Auditory Processing Disorder, Hearing Impaired (Partially), Hearing, Hearing Abnormality
- Trial name
- CAPD-LOOT (NCT07304024)
- Testing
- Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Colorado, Denver
Developmental Delays
Empower EI: Comparing Early Intervention Approaches to Improve Communication in Toddlers With Developmental Delays
This study is testing three ways to deliver Early Intervention (EI) services for toddlers with developmental disabilities (DD). Children enrolled in EI speech therapy will receive one of three approaches: 1.
- Trial name
- NCT07227974
- Testing
- Therapist-Delivered Early Intervention Approach, Caregiver Coaching Early Intervention Approach, Parents Taking Action
- Where
- United States
- Volunteers
- 1,269 people
- Sponsor
- Northwestern University
Developmental Language Disorder
Contextual Word Learning in Children With Developmental Language Disorder
Many children have developmental language disorder, which makes it difficulty to learn language, including vocabulary, and results in ongoing academic and social difficulties.
- Trial name
- NCT05988190
- Testing
- Contextual Word Learning Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Binghamton University
Developmental Language Disorders
Treating Passive Structure Knowledge Deficits in School-Age Children With Developmental Language Disorder
The goal of this project is to compare the relative effectiveness of two novel treatments to improve the knowledge of the passive sentence structure of school-age (8-11-year-old) children with developmental language disorder…
- Trial name
- DLDTreatment (NCT06932016)
- Testing
- Grammar Treatment
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- Ohio University
Stuttering, Developmental Stuttering
Noninvasive Thalamocortical Neuromodulation With Low-Intensity Focused Ultrasound for Persistent Developmental Stuttering
This research is studying the use of low-intensity focused ultrasound (LIFU; a mild, noninvasive acoustic stimulation technique) in a small number of people to learn about its safety as a treatment for stuttering.
- Trial name
- NCT07668882
- Testing
- High DC LIFU
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Autism, Autism Spectrum Disorder
Word Learning From Parentese in Autistic Children
The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are…
- Conditions
- Autism, Autism Spectrum Disorder, Neurodevelopmental Disorders
- Trial name
- NCT06649916
- Testing
- Parentese Speech, Adult Registered Speech
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Autism Spectrum Disorder, Language Disorders
Treatment of Social and Language Deficits With Leucovorin for Young Children With Autism
The primary objective of this study is to evaluate the cognitive and behavioral effects of liquid leucovorin calcium on young children with autism spectrum disorder (ASD) and determine whether it improves social communication as…
- Trial name
- NCT04060030
- Testing
- Levoleucovorin Calcium
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Southwest Autism Research & Resource Center
Autism Spectrum Disorder
How Simplified Language Affects Comprehension and Learning in Young Autistic Children
The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with ASD.
- Trial name
- PALS (NCT05707923)
- Testing
- Linguistic simplification
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Michigan State University
Developmental Language Disorder, Healthy Subjects
The Short-term Verbal Memory Endophenotype for Developmental Language Disorder Language Disorder
The goal of this clinical trial is to determine how memory and attention affect the ability of children with developmental language disorder (DLD) to learn and use new vocabulary.
- Trial name
- NCT06968169
- Testing
- Supportive learning, Cascades
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
ADHD, Dyslexia
Dual Executive Function Training Package
Executive function (EF) refers to the cognitive processes that enable goal-directed regulation of thoughts, emotions, and behaviours.
- Conditions
- ADHD, Dyslexia, Autism
- Trial name
- NCT07262853
- Testing
- Executive Function Training
- Where
- Hong Kong
- Volunteers
- 288 people
- Sponsor
- Education University of Hong Kong
Developmental Language Disorder
Language Outcomes, Mechanisms, and Trajectories in Adults With and Without Developmental Language Disorder
The investigators' overall objective is to characterize the long-term outcomes of Developmental Language Disorder (DLD) in adulthood and to identify specific cognitive mechanisms mediating these outcomes.
- Trial name
- NCT06898671
- Testing
- Eye-Tracking in Visual World Paradigm
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Developmental Delay Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS)
Repetitive Transcranial Magnetic Stimulation Combined With Language Training for Language Disorders in Children With Global Developmental Delay
This study explores a safe and effective new approach to improve language function in children with Global Developmental Delay (GDD).
- Conditions
- Developmental Delay Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS), Global Developmental Delay, Language Disorders in Children
- Trial name
- NCT07369960
- Testing
- Transcranial magnetic stimulation, individualized language training
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xiangya Hospital of Central South University
Autism Spectrum Disorder
Effects of Receptive Language Intervention vs Individual Therapy for Preschool Children With Autism Spectrum Disorder.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and social interaction and the presence of restricted, repetitive behaviors.
- Trial name
- NCT06927518
- Testing
- Receptive language intervention by using the total communication
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder, Language Development
HR-EEG Contribution in Prognostic Evaluation of Language Development in Children With ASD
The goal of this prospective observational multicentric cohort study is to evaluate the clinical prognostic value of the speech tracking score of language development in children with ASD aged from 3 years to 4 years and half at…
- Conditions
- Autism Spectrum Disorder, Language Development, Neurocognitive Disorders, Child Language
- Trial name
- EE-TSA-LANG (NCT05586672)
- Testing
- EEG-HR, ADI-R, ADOS-2
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de Santé Barthélemy Durand
Developmental Dyslexia
Brain Stimulation With Combined Reading and Motor Training for Children With Dyslexia
This study examines whether combining non-invasive brain stimulation (tDCS) with an integrated reading-and-motor training program improves reading and phonological processing in 9-year-old boys with developmental dyslexia.
- Trial name
- NCT07781761
- Testing
- Active transcranial direct current stimulation (tDCS), Phonological awareness training, Non-targeted fine motor training
- Where
- Iran
- Volunteers
- 160 people
- Sponsor
- Shahid Beheshti University
Autism Spectrum Disorder
More and Less Social Comprehension
The goal of this early Phase 1 clinical trial is to assess if the social content of a story impacts autistic children's listening comprehension of stories.
- Trial name
- MLSC (NCT06116552)
- Testing
- More Social Stories, Less Social Stories
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Kansas Medical Center
Development Delay, Child Development
Psychological Correlates of Developmental Delays in Preschool Children
The goal of this observational study is to investigate perinatal, cognitive, linguistic and social-emotional correlates of developmental delays of preschool children.
- Conditions
- Development Delay, Child Development, Social Functioning, Speech Delay
- Trial name
- NCT07420829
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Coronary Heart Disease (CHD), Artifical Intelligence
Construction and Validation of a Coronary Artery Disease-Specific Large Language Model and Its Evaluation Framework (CorAI)
Coronary artery disease (CAD) affects an estimated 11.39 million people in China, and mortality has continued to rise since 2012.
- Trial name
- CorAI (NCT07766551)
- Testing
- No Intervention: Observational Cohort
- Where
- 3 sites in China
- Volunteers
- 640 people
- Sponsor
- China National Center for Cardiovascular Diseases
Developmental Language Disorder, Speech Sound Disorder
A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production
The broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning.
- Conditions
- Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
- Trial name
- NCT04558541
- Testing
- Sensitivity to phonological rules, Sensitivity to semantic category cues.
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home