Clinical trials: Language Disorder
Developmental Language Disorder
The Effect of Prior Learning on Treatment of Morpheme Errors
This is a small-scale treatment study designed to determine which teaching methods result in the best learning. Treatment focuses on helping children with a developmental language disorder learn parts of grammar.
- Trial name
- NCT05953077
- Testing
- Conversational recasting
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Arizona
Social Anxiety Disorder, Selective Mutism
Treatment of Social Anxiety Disorder and Selective Mutism
This study is to assess the efficacy of a brief, 11-week, manualized Taming Sneaky Fears for Social Anxiety Disorder (SAD) and/or Selective Mutism (SM) child and parent group Cognitive Behavioural Therapy (CBT) treatment…
- Trial name
- SAD&SMTRMT (NCT02554929)
- Testing
- Taming Sneaky Fears, Parent Psycho-education and Child Socialization
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- The Hospital for Sick Children
Apraxia of Speech, Aphasia, Acquired
Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)
The purpose of the proposed research is to examine the effects of two treatment approaches on speech production involving speakers with chronic apraxia of speech (AOS) and aphasia.
- Conditions
- Apraxia of Speech, Aphasia, Acquired, Speech Disorders
- Trial name
- EPG&SPT (NCT02554513)
- Testing
- EPG Tx, SPT
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- VA Office of Research and Development
Alzheimer Disease
Treatment of Language and Memory in Patients With Alzheimer's Disease
The purpose of this study is to collect data on the effects of behavioral interventions for memory and communication deficits in persons taking cholinesterase inhibitors compared with the effects of cholinesterase inhibitors…
- Trial name
- NCT00593372
- Testing
- Spaced Retrieval Training
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Arkansas
Aphasia, Cerebrovascular Accident
Treating Intention In Aphasia: Neuroplastic Substrates
The purpose of this study is to determine if an "intentional act" improves treatment response for patients with nonfluent aphasia. The treatment involves naming pictures and saying members of categories.
- Trial name
- NCT00567242
- Testing
- Word-finding with intention component, Word-finding with no intention component
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Aphasia, Primary Progressive Aphasia
Circuitry Assessment and Reinforcement Training Effects on Recovery
This study investigates if electroencephalography (EEG) neurofeedback training is more beneficial than sham feedback training for the improvement of communication, anxiety, and sleep quality in individuals with aphasia.
- Conditions
- Aphasia, Primary Progressive Aphasia, Stroke
- Trial name
- CARTER (NCT04290988)
- Testing
- EEG Neurofeedback
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Johns Hopkins University
Fragile X Syndrome, Genetic Diseases
Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome
The purpose of the study is to test the efficacy of a 20 week multi-modal treatment comprised of lovastatin or placebo, and the Parent-implemented Language Intervention (PILI) in children with fragile X syndrome (FXS).
- Trial name
- NCT02642653
- Testing
- Lovastatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Autism Spectrum Disorder, Apraxia of Speech
Video Assisted Speech Technology to Enhance Motor Planning for Speech
Nearly 3.5 million Americans are diagnosed with Autistic Spectrum Disorder (ASD), a communication disorder that causes skill limitations in the areas of language acquisition, sensory integration, and behavior.
- Trial name
- VAST (NCT04764539)
- Testing
- Video Assisted Speech Therapy (VAST)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- iTherapy, LLC
Attention Deficit Hyperactivity Disorder, Reading Disorder
Comparison of Atomoxetine and Placebo in Children With Attention-Deficit/Hyperactivity Disorder (ADHD) and/or Reading Disorder (RD)
To test the hypothesis that a 4 week treatment with atomoxetine is more effective than placebo in patients with combined type Attention Deficit/Hyperactivity Disorder (ADHD), patients with only Reading Disorder, and patients with…
- Trial name
- NCT00191906
- Testing
- Atomoxetine Hydrochloride
- Where
- 5 sites in Belgium, Netherlands
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Bibliotherapy
Guided Self-help for Common Mental Disorders
Common mental disorders (CMDs) like depression and anxiety account for a large proportion of disability worldwide. Access to effective treatments like cognitive-behavioral therapy (CBT) is limited and has not reduced the public…
- Trial name
- DWM (NCT04870099)
- Testing
- Doing What Matters in Times of Stress: An Illustrated Guide
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hoarding Disorder, Hoarding
Enhancing Treatment of Hoarding Disorder With Personalized In-Home Sorting and Decluttering Practice
The proposed study aims to investigate the efficacy of adding in-home decluttering practice to Buried in Treasures Workshop (BIT) facilitated group treatment for hoarding disorder.
- Conditions
- Hoarding Disorder, Hoarding, Clutter
- Trial name
- BITS (NCT02843308)
- Testing
- Facilitated group therapy with behavioral practice; 18 weeks
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Stanford University
Neonatal Death, Perinatal Death
Leveraging Interactive Text Messaging to Monitor and Support Maternal Health in Kenya
Mobile health (mHealth) interventions such as interactive short message service (SMS) text messaging with healthcare workers (HCWs) have been proposed as efficient, accessible additions to traditional health care in…
- Conditions
- Neonatal Death, Perinatal Death, Depression
- Trial name
- AI-NEO (NCT05369806)
- Testing
- Interactive two-way SMS dialogue
- Where
- 2 sites in Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Parkinson Disease
Low Frequency Subthalamic Nucleus Deep Brain Stimulation to Improve Verbal Fluency
Rationale: Parkinson's disease patients with deep brain stimulation electrodes represent a unique opportunity to study the influence of basal ganglia on neurocognitive function.
- Trial name
- NCT04383665
- Testing
- STN DBS 10Hz, STN DBS 130Hz, STN DBS off
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Southern California
Hoarding Disorder, Hoarding
Hoarding Disorder Treatment With Virtual Reality
This study explores whether a facilitated peer support group called Buried in Treasures (BIT) and a virtual reality decluttering practice can help individuals with clutter challenges.
- Conditions
- Hoarding Disorder, Hoarding, Clutter
- Trial name
- HDVR (NCT03828461)
- Testing
- Facilitated group therapy with behavioral practice; 16 weeks
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stanford University
Language Disorders in Children
Training Grammar With Meaning
This study will enroll children between the ages of 4 and 6 years of age who exhibit significant difficulty developing language skills without any other handicapping conditions.
- Trial name
- NCT06250101
- Testing
- Enhanced Conversational Recast treatment
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Arizona
Aphasia, Language Disorders
Word-Retrieval Treatment for Aphasia: Semantic Feature Analysis
The purpose of this investigation is to further develop and test a treatment for word-finding problems in aphasia. The treatment is designed to strengthen meaning associations within categories of words (e.g., animals, tools…
- Conditions
- Aphasia, Language Disorders, Speech Disorders
- Trial name
- NCT00125242
- Testing
- Semantic Feature Analysis (SFA)Training
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Rehabilitation of Speech and Language Disorders, Speech Disorders
MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal Impairments
This study will evaluate the ability of MyoVoice to replace natural speech. Referred to generally as an Augmentative and Alternative Communication (AAC) device, MyoVoice uses electrical signals recorded non-invasively from speech…
- Conditions
- Rehabilitation of Speech and Language Disorders, Speech Disorders, Speech, Alaryngeal, Communication Aids for Disabled
- Trial name
- NCT04762043
- Testing
- Experimental System: MyoVoice, Reference System: Electrolarynx
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Altec Inc.
Sleep Disturbance
Developing and Testing a Spanish-Language Intervention to Reduce Cancer-Related Sleep Disturbance
The purpose of this study is to learn about how to provide treatment to cancer survivors who have difficulty sleeping.
- Trial name
- NCT04101526
- Testing
- Spanish-language Cognitive-Behavioral Therapy for Insomnia (CBT-I) delivered via videoconference
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 30 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Peer Influence
Penetrating the Classroom Social Network for Children With Language Impairment Via Peer Mediated Intervention
This exploratory experiment is designed to determine the extent to which the socialization experiences and social, behavioral, and linguistic skills of preschoolers with language impairment (LI) can be improved.
- Trial name
- PEERS (NCT06182033)
- Testing
- Peer-mediated pivotal response training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Hearing Loss, Sensorineural, Dysarthria
Application of Ideal Binary Masking to Disordered Speech
Dysarthria and hearing loss are communication disorders that can substantially reduce intelligibility of speech and the addition of background noise adds a further challenge.
- Trial name
- NCT05244603
- Testing
- Ideal binary mask
- Where
- United States
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Utah State University