Clinical trials: Language Disorder
Aphasia
Aerobic Exercise and Aphasia Treatment
The purpose of the study is to determine if speech therapy can be enhanced by Aerobic Exercise (AE). Investigators will use a single subject design to determine if aphasia therapy result in greater gains when combined with…
- Trial name
- NCT02999360
- Testing
- Language therapy, Background Music, Aerobic Exercise
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- NYU Langone Health
Stammering
Modifying Unconscious Tongue Movements in Adults With Developmental Stammer.
This is a pilot randomised controlled trial investigating whether using modification of saccadic eye movements can control lateral unconscious tongue positioning and enhance fluency in adults with a confirmed developmental…
- Trial name
- NCT04310436
- Testing
- Modifying saccades by looking down to naval., Modifying saccades by looking in air.
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute of Technology, Sligo
Coronary Artery Disease, Atrial Fibrillation (AF)
Medical Large Language Model-Assisted Diagnosis and Treatment in Primary Care Chronic Disease Management
This study aims to explore the feasibility of using medical large language models to assist in chronic disease management. By setting up experimental and control group interventions and having experts blindly evaluate anonymized…
- Conditions
- Coronary Artery Disease, Atrial Fibrillation (AF), Heart Failure, Stroke
- Trial name
- NCT07740044
- Testing
- Medical large language model
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Jiangsu Taizhou People's Hospital
Acute Hemorrhagic Stroke
AI-Driven Early Warning System for Perioperative Risks in Acute Hemorrhagic Stroke
Acute hemorrhagic cerebrovascular disease is a life-threatening condition characterized by sudden onset, rapid progression, multiple complications, poor prognosis, and high mortality.
- Trial name
- NCT06998082
- Where
- China
- Volunteers
- 1,533 people
- Sponsor
- Beijing Tiantan Hospital
Alzheimer's Disease, Primary Progressive Non-fluent Aphasia
A Medium Chain Triglyceride Intervention for Patients With Alzheimer Disease
The purpose of this study is to determine safety, tolerability, and pharmacokinetics/dynamics of a ketogenic dietary supplement containing medium chain triglycerides (MCTs) in patients with Alzheimer disease (AD).
- Conditions
- Alzheimer's Disease, Primary Progressive Non-fluent Aphasia, Frontotemporal Dementia (FTD)
- Trial name
- MINT-01 (NCT02912936)
- Testing
- Ketogenic medium chain triglyceride drink (MCT drink)
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University of British Columbia
Aphasia
TMS in Aphasia Recovery
Stroke often causes substantial problems in speaking or understanding speech. Treatments for these problems are currently very limited.
- Trial name
- NCT04777214
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pennsylvania
Diabetes
Natural Language Processing and Quality Assessment in Primary Care
The investigators propose to use a Natural Language Processing System (NLP) to provide an initial baseline report for primary care patients at risk for diabetes and cardiovascular complications that will include: a) evidence of…
- Trial name
- NCT01023243
- Testing
- Brochure: Care of the Feet for Those at Risk, Quality Survey: foot exam, tobacco and aspirin use
- Where
- United States
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Heart Failure
Patient-Executed, Clinician-Confirmed Diuretic Titration in Pulmonary Artery Pressure-Guided Heart Failure (SURPASS-HF)
SURPASS-HF was a 90-day, single-center, single-arm, prospective feasibility study asking whether adults with heart failure and an implanted pulmonary artery (PA) pressure sensor can safely share in managing their own diuretic…
- Trial name
- SURPASS-HF (NCT07743125)
- Testing
- Shared-management diuretic titration guided by remote PA pressure monitoring
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical College of Wisconsin
Dementia, Alzheimer Disease
Digital Interventions in Neuro-Rehabilitation: Gotcha!
Aims and background Everyone forgets the names of people they should know at times. Having dementia makes this problem worse. People with dementia have told expressed they forget the names of people they care about and this can…
- Conditions
- Dementia, Alzheimer Disease, Anomia
- Trial name
- NCT04570215
- Testing
- Gotcha! Therapy application, Gotcha Therapy application: Maintenance
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Stroke, Aphasia
MIT Intensive Treatment Study
This study is examining the use of intensive melodic intonation therapy and video feedback as a means of aiding individuals with nonfluent aphasia and co-occurring motor speech impairments.
- Conditions
- Stroke, Aphasia, Motor Speech
- Trial name
- MITTXS (NCT06213376)
- Testing
- Melodic Intonation Therapy, Video Feedback Performance Review
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Nevada State University
Speech Impairment, Speech Disorder
Voiceitt for People With Impairments in Speech
The primary objective of this pilot study is to evaluate the feasibility and preliminary effectiveness of the Voiceitt app in improving communication for individuals with speech impairments due to conditions such as cerebral…
- Trial name
- NCT06874322
- Testing
- Voiceitt
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Tinnitus
Fudan Tinnitus Doctor for Tinnitus Management
The goal of this clinical trial is to evaluate whether a conversational artificial intelligence-based digital intervention can improve symptoms in adults with chronic subjective tinnitus.
- Trial name
- NCT07558837
- Testing
- Fudan Tinnitus Doctor (FTD) System, Non-conversational Digital Education Program
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Obsessive-Compulsive Disorder, Anxiety Disorders
Improving Access to Child Anxiety Treatment
There is strong evidence that cognitive behavioral therapy (CBT) with exposure is the preferred treatment for youth with anxiety disorders, but outpatient services that provide this type of treatment are limited.
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Pediatric Disorder, Anxiety
- Trial name
- IMPACT (NCT03528109)
- Testing
- Exposure Therapy
- Where
- United States
- Volunteers
- 379 people
- Sponsor
- Bradley Hospital
Irritable Bowel Syndrome
Efficacy Evaluation of a Commercial Preparation Containing Lactobacillus Casei DG on the Reduction of the Painful Symptoms Related to the Irritable Bowel Syndrome (IBS). A Pilot Clinical Study
The purpose of this study is to evaluate the efficacy of a treatment with Lactobacillus casei DG in the reduction of the painful symptoms in patients affected by irritable bowel syndrome.
- Trial name
- NCT02077699
- Testing
- Lactobacillus casei DG
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- SOFAR S.p.A.
Diagnosis
Physician Reasoning on Diagnostic Cases With Large Language Models
This study will evaluate the effect of providing access to GPT-4, a large language model, compared to traditional diagnostic decision support tools on performance on case-based diagnostic reasoning tasks.
- Trial name
- NCT06157944
- Testing
- GPT-4
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stanford University
Developmental Dyslexia
Telerehabilitation vs. in Presence Rehabilitation of Reading Disorders Using the Rhythmic Reading Training (RRT)
The aim of the study is to compare the effectiveness of telerehabilitation vs. in presence rehabilitation of reading disorders, using a rhythm-based intervention for reading (i.e., Rhythmic Reading Training)
- Trial name
- NCT04995471
- Testing
- In presence RRT - prototype software, In presence RRT - online platform, Tele-RRT - prototype software
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Catholic University of the Sacred Heart
Condition Category Concordance
3M-6D Educational Intervention to Improve LLM-Assisted Medical Consultation in Neurology Outpatients
This study will evaluate whether three-minute six-dimension education (3M-6D education) can improve the reliability of large language models (LLMs) as medical assistants in neurology outpatients.
- Trial name
- LAMP-2 (NCT07844044)
- Testing
- three minutes six dimensions education, ChatGPT
- Where
- 4 sites in China
- Volunteers
- 396 people
- Sponsor
- Capital Medical University
Stroke
A Validity and Reliability Study for Urdu Version of Rivermead Mobility Index in Stroke Patients
The aim of the study is to translate and cross-culturally adapt the Rivermead mobility index questionnaire into traditional Urdu language to investigate its psychometric properties (reliability \& validity) for those patients who…
- Trial name
- NCT06406036
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke
RCT of HeartBot in Women
The goal of this clinical trial is to find out whether an app-based program called HeartBot II, which uses an artificial intelligence (AI) chatbot, can help improve women's awareness and knowledge of heart attacks in women.
- Conditions
- Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke, Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease, Participants Should Not be a Healthcare Professionals or Healthcare Trainees
- Trial name
- HeartBot II (NCT07416734)
- Testing
- HeartBot II Program, Waitlist Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Epilepsy
Analysis of Lateralization of Language in Epileptic Children by Near-infrared Spectroscopy (NIRS)
Recent data published by various laboratories as well as our preliminary data tend to prove that near-infrared spectroscopy can be used to determine the lateralization of language as part of the preoperative assessment for…
- Trial name
- LANGLAT (NCT02799108)
- Testing
- NIRS, fMRI
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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