Clinical trials: Laparoscopic Appendectomy
Appendicitis, Appendectomy
Appendectomy by Low Impact Laparoscopy vs Routine Laparoscopy : a Randomized Prospective Monocentric Trial
Introduction: Surgery performed under low insufflation pressure combined with micro-laparoscopy (incisions 4X smaller than incisions in conventional laparoscopy) is called "low impact laparoscopy" or LIL.
- Trial name
- LIL-APP (NCT04614519)
- Testing
- Conventional group, Low impact laparoscopy group
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Appendicitis, Surgery
Closure of the Appendix Stump in Laparoscopic Appendectomy
Aimed to the study evaluate the superiority of intracorporal sutures and Hem-o-lok clips in terms of efficiency.
- Trial name
- NCT03930667
- Testing
- clips, knotting
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Orhan Üreyen
Appendicitis Acute
Investigation of Oxidative Stress in Appendectomy - Open Versus Laparoscopic in Childhood and Adolescence
In the planned prospective randomized study, oxidative stress will be investigated by analyzing volatile organic compounds in the exhaled air in children.
- Trial name
- OSAE (NCT03723642)
- Testing
- Initial serum malondialdehyde level, Final serum malondialdehyde level, Initial differential white blood cell count
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Graz
Appendectomy, Laparoscopy
TAP Block or Wound Infiltration for Laparoscopic Pediatric Appendectomy: a Pilot Study
Effectiveness of the TAP block compared to wound infiltration in controlling pain after laparoscopic appendectomy in children
- Conditions
- Appendectomy, Laparoscopy, Anesthesia, Conduction, Child, Preschool
- Trial name
- NCT04294537
- Testing
- TAP Block, LIA local infiltration, General anesthesia
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Appendicitis
Single-incision Laparoscopic (SILS) Versus Conventional Laparoscopic Appendectomy for the Treatment of Acute Appendicitis
Recent advances in laparoscopic instrumentation have made it possible to perform intra-abdominal operations entirely through a small incision that can be hidden within the umbilicus.
- Trial name
- NCT00997516
- Testing
- SILS appendectomy, conventional laparoscopic appendectomy
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of California, San Francisco
Appendicitis, Cholecystitis
NOVOsyn® for Trocar Incision After Laparoscopic Appendectomy and Cholecystectomy
The aim of this study is to evaluate if the application of a Chlorhexidine coated suture (Novosyn® CHD) will reduce the colonization of bacteria in comparison to an uncoated suture (Novosyn®) used for the closure of trocar wounds…
- Trial name
- NOVOTILAC (NCT04033211)
- Testing
- Novosyn® CHD for fascia and skin closure, Novosyn® for fascia and skin closure
- Where
- 4 sites in Germany, Spain
- Volunteers
- 316 people
- Sponsor
- Aesculap AG
Appendectomy
Closure of the Appendiceal Stump
Laparoscopic appendectomy is a well-defined surgical technique. However, concerns remain about whether closure of the appendiceal stump should be done with clips, endoloops, staples, or other techniques.
- Trial name
- NCT06443749
- Testing
- appendectomy
- Volunteers
- 48 people
- Sponsor
- Sezgin Topuz
Appendicitis Acute, Appendicitis
Clinical Trial for a Outpatient Clinical Management of Urgent Laparoscopic Appendectomy
The aim of this study is to evaluate the safety and efficacy of outpatient management of uncomplicated acute appendicitis. For this purpose, a randomized clinical trial was designed.
- Trial name
- ASI (NCT05401188)
- Testing
- Outpatient, hospitalization
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- HJ23
Emergencies
Nomogram for Predicting Difficult Laparoscopic Appendectomy
No prior studies have stratified the difficulty of laparoscopic appendectomy (LA). The investigators aimed to investigate preoperative factors as indicators of difficult LAs based on the experience of surgical trainees and to…
- Trial name
- NCT06818942
- Testing
- Observations on preoperative and intraoperative factors influencing the difficulty of surgery
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai 6th People's Hospital
Bowel Obstruction
Bowel Obstruction Post Open Versus Laparoscopic Appendectomy
Acute appendicitis is one of the most common causes of acute abdominal pain requiring surgical intervention, with appendectomy being the definitive treatment .
- Trial name
- NCT07716709
- Testing
- Open appendectomy, Laparoscopic appendectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Laparoscopic Appendectomy
Evaluating the Effects of a Structured Training Program on the Learning Curve of Residents in Laparoscopic Surgery
1.1 Aim The investigators wish to validate a structured training program for junior residents to enhance their learning curves in performing laparoscopic appendectomy.
- Trial name
- NCT02665000
- Testing
- Structured training programme
- Where
- 2 sites in Singapore
- Volunteers
- 20 people
- Sponsor
- National University Hospital, Singapore
Laparoscopic Appendectomy
Comparison Between Metallic Clip Ligation and Suture Ligation of Appendicular Stump in Laparoscopic Appendectomy
Laparoscopic appendectomy is the standard procedure for acute appendicitis. Among the various steps of the procedure one of the rate limiting step is the ligation of the appendicular stump which can be done using suture material…
- Trial name
- NCT07129746
- Testing
- Metallic clip ligation of the appendicular stump, Suture ligation of appendicular stump
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- Jinnah Hospital
Loxoprofen Sodium Patch, Local Incision
The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Laparoscopic Surgery
Studies have shown that up to 80% of patients experience postoperative pain following laparoscopic surgery due to inflammation caused by surgical incisions and surrounding tissues, necessitating pharmacological relief.
- Conditions
- Loxoprofen Sodium Patch, Local Incision, Laparoscopic Cholecystectomy, Appendectomy, Laparoscopic
- Trial name
- NCT07591207
- Testing
- Loxoprofen Sodium Patch on the contralateral side, Loxoprofen Sodium Patch on the incision site
- Where
- 2 sites in China
- Volunteers
- 134 people
- Sponsor
- Beijing Tiantan Hospital
Appendectomy, Laparoscopic, Endoscopy
Transrectal NOTES Appendectomy - Feasibility Study
Natural orifice translumenal endoscopic surgery (NOTES) has revolutionized the concept of minimally invasive surgery. NOTES is currently performed through transgastric or transvaginal approaches.
- Trial name
- NCT01189916
- Testing
- Endoscopically assisted Appendectomy Surgery
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Northwestern University
Transcutaneous Electrical Acupoint Stimulation
Effects of TEAS on Postoperative Recovery of Intestinal Function in Children Undergoing Laparoscopic Appendectomy
With the development of surgical techniques, laparoscopic appendectomy has become a standard therapeutic procedure for acute appendicitis in many hospitals in recent years, which is considered as an effective and safe treatment…
- Trial name
- NCT05379660
- Testing
- transcutaneous electrical acupoint stimulation
- Volunteers
- 200 people
- Sponsor
- Xian Children's Hospital
Appendicitis
Safety and Efficacy Study of Single Port Laparoscopic Appendectomy in Acute Appendicitis
The aim of this study is to investigate the safety and efficacy of single port laparoscopic appendectomy compared with conventional laparoscopic appendectomy in adults with acute appendicitis.
- Trial name
- NCT01007318
- Testing
- Single port laparoscopic appendectomy, 3 port laparoscopic appendectomy
- Where
- South Korea
- Volunteers
- 194 people
- Sponsor
- Kyunghee University Medical Center
Appendicitis
Non Absorbable Clips vs Endoloops in Laproscopic Appendicectomy
a) Compare between Nonabsorbable Polymeric Clips and Endoloop ligatures regarding: 1. technical difficulties. 2. operation time. 3. cost effectiveness. 4. postoperative complications. 5. inpatient stay.
- Trial name
- NCT04094480
- Testing
- polymeric non absorbable clips, endoloops
- Volunteers
- 40 people
- Sponsor
- Assiut University
Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness
Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic Appendectomy
Abstract Objective: The aim of this study is to compare two different ways of adjusting the air-filled cushion (cuff) of the breathing tube used during general anesthesia in children undergoing laparoscopic appendectomy (closed…
- Conditions
- Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness, Airway Complications, Respiratory Complications
- Trial name
- NCT07678086
- Testing
- Pressure Transducer, Traditional Palpation Method
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Laparoscopic Appendectomy
Comparing Pain Relief Between Two Methods of Freezing Injections in Children Having Their Appendix Removed
Laparoscopic appendectomies are the most common emergency surgeries performed in children. Despite being considered minimally invasive surgeries, they can result in substantial postoperative pain and 2 of 3 patients require…
- Trial name
- NCT06945263
- Testing
- Rectus Sheath Block, Local Anesthetic at the Umbilical Port Site, Intravenous Dexamethasone
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Appendicitis
Open Appendectomy Versus Laparoscopic Appendectomy
1. Laparoscopic appendectomy may not be a superior procedure when compared with open appendectomy; 2. Various modifications in laparoscopic appendectomy procedure may reduce the technical diffuculty and overall costs.
- Trial name
- NCT01260064
- Testing
- Open appendectomy, Laparoscopic appendectomy with metal endoclips, Laparoscopic appendectomy with suture ligation
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital