Clinical trials: Laparoscopic Cholecystectomy
Cholelithiasis
Incisional Hernia Rate After Single-incision Laparoscopic Cholecystectomy
Single-incision laparoscopic cholecystectomy (SILC) requires a larger incision than standard laparoscopy, which may increase the incidence of incisional hernias.
- Trial name
- NCT03768661
- Testing
- Single-incision Laparoscopic cholecystectomy, Laparoscopic Cholecystectomy
- Where
- Spain
- Volunteers
- 185 people
- Sponsor
- Hospital Plató
Cholelithiasis, Choledocholithiasis
Trial Comparing Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy
This study aims to evaluate post-operative pain in single-incision laparoscopic cholecystectomy (SILC) versus the conventional four port technique (LC).
- Conditions
- Cholelithiasis, Choledocholithiasis, Cholecystolithiasis, Pancreatitis
- Trial name
- NCT01824186
- Testing
- SILC, LC
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Gallstones, Cholelithiasis
RCT: Multi-modal Analgesia for Laparoscopic Cholecystectomy
Analgesic efficacy of multi-modal analgesia is superior to standard analgesia for patients undergoing elective laparoscopic cholecystectomy for symptomatic cholelithiasis.
- Conditions
- Gallstones, Cholelithiasis, Pain
- Trial name
- LapChole (NCT01972620)
- Testing
- Bupivacaine
- Where
- Serbia
- Volunteers
- 63 people
- Sponsor
- Klinicki Centar Vojvodine
Cholecystectomy, Laparoscopic
Clinical Study of Single Incision Laparoscopic Cholecystectomy in the Treatment of Patients With Acute Cholecystitis
Gallstone is a common disease in China.At present, the prevalence of gallstones in China is 15 %, and about 210 million people are sick.
- Trial name
- NCT06074679
- Testing
- Open cholecystectomy
- Where
- 5 sites in China
- Volunteers
- 600 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cholecystectomy
Comparison of Quadratus Lumborum and Transverse Abdominis Plane Blocks With Intravenous Analgesic in Gallbladder Surgery
Patients who will undergo laparoscopic gallbladder surgery are expected to experience less postoperative pain and have less need for morphine-derived painkillers.
- Trial name
- NCT06058195
- Testing
- Quadratus lumborum plane block, Transverse abdominis plane block, Intravenous analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Choledocholithiasis, Cholelithiasis
Laparoendoscopic Rendez Vous Versus Standard Two Stage Approach for the Management of Cholelithiasis/Choledocholithiasis
The purpose of the study is to assess whether combined intraoperative ERCP and CBD clearance with laparo-endoscopic rendez-vous during laparoscopic cholecystectomy (one stage approach) is or not superior to the standard practice…
- Trial name
- NCT00416234
- Testing
- Laparoendoscopic Rendez vous, preoperative ERCP and CBD clearance
- Where
- Greece
- Volunteers
- 300 people
- Sponsor
- University of Thessaly
Optic Nerve Sheath Diameter
Changes in Optic Nerve Sheath Diameter in Desflurane Based General Anesthesia During Laparoscopic Cholecystectomies
In this study, the investigators to observe the effects of different fresh gas flow rates, which are frequently used in general anesthesia practice, on optic nerve sheath diameter during laparoscopic cholecystectomy surgeries…
- Trial name
- NCT06896604
- Testing
- Ocular Ultrasonography for measuring Optic Nerve Sheath Diameter
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Cholelithiasis, Cholecystectomy, Laparoscopic
Unilateral Laparoscopic TAP Block vs. Local Infiltration in Post-Cholecystectomy Analgesia
This study compared different methods of pain control after laparoscopic gallbladder removal. A total of 160 patients were randomly assigned to receive either a unilateral laparoscopic TAP block, local anesthetic infiltration, a…
- Conditions
- Cholelithiasis, Cholecystectomy, Laparoscopic, Pain, Postoperative, Anesthesia, Local
- Trial name
- TAP vs LAI (NCT07176299)
- Testing
- Unilateral laparoscopic TAP block (0.25% bupivacaine), Local anesthetic infiltration (0.25% bupivacaine), Combined TAP block and local anesthetic infiltration (0.25% bupivacaine)
- Where
- Poland
- Volunteers
- 160 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Healthy
Clinical Evaluation of Spring-Type Laparoscopic Clip Technology
The Visu-Loc spring clip is being used to occlude the cystic duct at the time of laparoscopic cholecystectomy. A hepato-iminodiacetic acid (HIDA) scan will be completed on post operative day one to check for biliary leaks.
- Trial name
- NCT00527644
- Testing
- 5mm spring clip
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cholecystectomy, Elective Surgery
Comparison Of Dexmedetomidine and Fentanyl In Attenuation Of Hemodynamic Response To Direct Laryngoscopy And Intubation In Patient Undergoing Laparoscopic Cholecystectomy.
Compare effects of intravenous dexmedetomidine and fentanyl in attenuation of intubation response in a patient undergoing laparoscopic cholecystectomy.
- Trial name
- NCT04089592
- Testing
- Dexmedetomidine, Fentanyl
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
General Anesthesia, Electroencephalography
Electroencephalographic Profiles During General Anesthesia: a Comparative Study of Remimazolam and Propofol
How anesthetic drugs induce and maintain the behavioral state of general anesthesia is an important question in medicine and neuroscience.
- Conditions
- General Anesthesia, Electroencephalography, Laparoscopic Cholecystectomy, Remimazolam
- Trial name
- NCT05533567
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Pneumoperitoneum
Different Insufflation Flows and Effects on Cerebral Oxygenation in Laparoscopic Cholecystectomy
Previous studies conducted on the hemodynamic effects of pneumoperitoneum pressures created by different insufflation flows are very limited in the literature.
- Trial name
- NCT05992636
- Testing
- pneumoperitoneum insufflation (flow) rate
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Karadeniz Technical University
Gall Bladder Disease, Laparoscopic Cholecystectomy
The Effect of Mindfulness Meditation and Virtual Reality on Laparoscopic Cholecystectomy Patients
This study aims to compare the effects of the Theory of Human Caring based short-term mindfulness meditation and virtual reality on patients scheduled for laparoscopic cholecystectomy.
- Trial name
- NCT05724277
- Testing
- Mindfulness Meditation, Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ataturk University
Gallbladder Diseases
Effect of Lidocaine Patch for Shoulder Pain in Laparoscopic Cholecystectomy
The primary purpose of this study is to investigate the effect of lidocaine patch on the shoulder pain score after end of surgery.
- Trial name
- NCT02827136
- Testing
- Lidocaine patch and hypafix, hypafix
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Ajou University School of Medicine
Pneumoperitoneum
Comparing Nitrous Oxide and Carbon Dioxide for Laparoscopic Cholecystectomy
There is no general agreement about the ideal gas for pneumoperitoneum. CO2, now in common use, has not compared to N2O sufficiently to disclose which one has minimal "physiological" invasiveness characters.
- Trial name
- NCT01512511
- Testing
- nitrous oxide use for pneumoperitoneum creation
- Where
- Iran
- Volunteers
- 64 people
- Sponsor
- Ahvaz Jundishapur University of Medical Sciences
Acute Pain, Postoperative Pain
Comparison of the Effectiveness of Preemptive Paracetamol and Ibuprofen in Acute Postoperative Pain
This study will evaluate two different analgesic regimen used for acute postoperative pain.
- Trial name
- NCT03063658
- Testing
- Paracetamol, Ibuprofen 800 mg
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Ankara University
Laparoscopic Cholecystectomy, Quadratus Lumborum Block
Erector Spinae Plane Block Versus Subcostal Anterior Quadratus Lumborum Block in Laparoscopic Cholecystectomy
Adequate analgesic regimen is one of the most important key elements of Enhanced recovery after surgery (ERAS) protocols. The cornerstone of analgesia is multimodal analgesia combining local anesthetic (LA) techniques and trying…
- Conditions
- Laparoscopic Cholecystectomy, Quadratus Lumborum Block, Erector Spinae Plane Block
- Trial name
- NCT05158270
- Testing
- Ultrasound Guided Erector spinae plane block, Ultrasound Guided Subcostal Anterior Quadratus Lumborum Block, Intravenous Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Zagazig University
Cholecystectomy, Laparoscopic, Cholelithiasis
Improvised Endobag vs Direct Gallbladder Extraction in Laparoscopic Cholecystectomy
Eligigble patients will be enrolled after obtaining informed consent. Basic information such as age, gender, body weight, smoking and alcohol history, number of gallstones, and gallbladder characteristics will be recorded.
- Trial name
- NCT07823803
- Testing
- Endobag
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rawal Institute of Health Sciences Islamabad
Laparoscopic Cholecystectomy
Comparison Between Dexmedetomidine and Fentanyl As an Adjuvant to Bupivacaine in the Paravertebral Nerve Block in Laparoscopic Cholecystectomy for Postoperative Analgesia: Randomized Comparative Clinical Trial.
Laparoscopic cholecystectomy is one of the most common surgeries today, cause it has many advantages over open cholecystectomy. Although these advantages pain remains a big problem after laparoscopic cholecystectomy which causes…
- Trial name
- NCT06752629
- Testing
- Bupivacaine and Dexmedetomidine, Bupivacaine and Fentanyl
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cholecystectomy
A Trial to Evaluate Natural Orifice Transgastric Endoscopic Cholecystectomy With Laparoscopic Assistance
The study will document being able to successfully perform transgastric cholecystectomy (laparoscopic visualization) using a small collection of study surgical tools.
- Trial name
- NCT00979186
- Testing
- NOTES GEN 1 Toolbox
- Where
- United States
- Sponsor
- Ethicon Endo-Surgery