Clinical trials: Laparoscopic Gastrectomy, open to volunteers
Gastric Cancer, Surgery
Clinical Outcomes of Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Extended Lymphadenectomy Beyond D2 for Locally Advanced Gastric Cancer (FUGES-30)
Taking patients with locally advanced gastric adenocarcinoma (cT2-4a, N-/+, M0) as the research subjects, to evaluate whether the clinical efficacy of laparoscopic beyond D2 regional lymph node dissection for gastric cancer with…
- Trial name
- NCT06945718
- Testing
- beyond D2 regional lymph node dissection
- Where
- China
- Volunteers
- 760 people
- Sponsor
- Fujian Medical University
Early Gastric Cancer, Adenocarcinoma of the Stomach
SPADE Clinical Trial.
Purpose: This multicenter, prospective, single-arm phase 2 clinical trial aims to evaluate the safety, feasibility, and clinical outcomes of the SPADE operation (Spade-Shaped Anastomosis) in patients undergoing laparoscopic or…
- Conditions
- Early Gastric Cancer, Adenocarcinoma of the Stomach, Proximal Gastric Cancer, SPADE Operation
- Trial name
- SPADE (NCT07892183)
- Testing
- Spade-Shaped Anastomosis after Laparoscopic or Robotic Proximal Gastrectomy Using Double Suture Anchoring between the Posterior Wall of the Esophagus and the Anterior Wall of the Stomac
- Where
- South Korea
- Volunteers
- 159 people
- Sponsor
- National Cancer Center, Korea
Dynamic Lung Compliance
Effects of Changes in Driving Pressure on Intraoperative Pulmonary Dynamic Compliance and PaO₂/FiO₂ Ratio in Laparoscopic Sleeve Gastrectomy
The goal of this prospective intervention study is to determine whether individualized positive end expiratory pressure (PEEP) titration targeting the minimum Driving pressure (ΔP) during LGS operation improves intraoperative…
- Trial name
- PEEP (NCT07494240)
- Testing
- incremental peep
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Beni-Suef University
Gastroesophageal Reflux, Sleeve Gastrectomy
Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction
Researchers are trying to identify predictors for gastroesophageal reflux disease after sleeve gastrectomy.
- Conditions
- Gastroesophageal Reflux, Sleeve Gastrectomy, Bariatric Surgery Complication
- Trial name
- NCT04411823
- Testing
- EndoFLIP measurement
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Ultrasound, External Oblique Intercostal Plane Block
Ultrasound-Guided External Oblique Intercostal Plane Block Versus Subcostal Transversus Abdominis Plane Block For Perioperative Analgesia in Laparoscopic Sleeve Gastrectomy
This study aims to compare the analgesic efficacy, duration of analgesia, and overall opioid consumption between the external oblique intercostal plane (EOIP) block and subcostal transversus abdominis plane (TAP) block in…
- Conditions
- Ultrasound, External Oblique Intercostal Plane Block, Subcostal Transversus Abdominis Plane Block, Perioperative Analgesia
- Trial name
- NCT07366138
- Testing
- External oblique intercostal plane block, Subcostal transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Gastrectomy, Postoperative Analgesia
Efficacy and Safety of Anrikefon Injection for the Treatment of Postoperative Pain in Patients Undergoing Totally Laparoscopic Radical Distal Gastrectomy
Anruikefen is a peripherally highly selective kappa receptor agonist that does not easily cross the blood-brain barrier, resulting in a low incidence of central adverse reactions such as respiratory depression, sedation, and…
- Trial name
- NCT07330063
- Testing
- Anruikefen (Intravenous Bolus), Anruikefen (Intravenous Infusion)
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Gastric Cancer
OGT-assisted Overlap Esophagojejunostomy Versus Traditional Overlap Method
Abstract Background Our previous studies have shown OGT method significantly simplified overlap esophagojejunostomy with good short-term outcomes, and provided new perspectives for optimizing esophagojejunostomy.
- Trial name
- OGT (NCT05450835)
- Testing
- OGT group, Overlap group
- Where
- 12 sites in China
- Volunteers
- 344 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Obesity, Morbid
Low Impact Laparoscopy In Bariatric Surgery
The goal of this clinical trial is to learn if low pressure pneumoperitoneum and small incisions (low impact laparoscopy, LIL) works to reduce pain and improve pulmonary function in patients underwent to bariatric surgery.
- Trial name
- LILYBET (NCT07119437)
- Testing
- low pneumoperitoneum laparoscopy with microsurgery, standard laparoscopy
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Postoperative Pain
Investigating the Analgesic Efficacy and Ease of Perfomance of Modified Throracoabdominal Plane Block and Comparing it With Erector Spinea Plane Block in Laparacopic Sleeve Gasterctomy Surgeries
Interest in surgical weight loss interventions continues to rise in the face of what has been dubbed the obesity epidemic. The most popular of these weight loss interventions is laparoscopic sleeve gastrectomy, which has proven…
- Trial name
- NCT07654556
- Testing
- Bupivacaine 0.25% (isobaric), Bupivaciane 0.25% (Isobaric)
- Volunteers
- 64 people
- Sponsor
- Cairo University
Gastric Cancer (GC)
Robotic vs Laparoscopic Gastrectomy for cT4a Gastric Cancer
The goal of this multicenter, randomized, phase III clinical trial is to test whether robot-assisted radical gastrectomy improves 3-year recurrence-free survival versus laparoscopy-assisted radical gastrectomy in adults aged…
- Trial name
- NCT07331454
- Testing
- Robotic Gastrectomy, Laparoscopic Gastrectomy
- Where
- China
- Volunteers
- 335 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Stomach Neoplasms
Multicenter Study on Laparoscopic Total Gastrectomy for Advanced Gastric Cancer
CLASS-07 trial is a prospective, multicenter, randomized controlled trial for comparison of long-term outcomes between laparoscopic total gastrectomy (LTG) and open total gastrectomy (OTG) in patients with locally advanced…
- Trial name
- CLASS-07 (NCT04710758)
- Testing
- Laparoscopic total gastrectomy, Open total gastrectomy
- Where
- China
- Volunteers
- 1,018 people
- Sponsor
- Shanghai Zhongshan Hospital
Gastric Cancer
Trial for Application of Laparoscopic Total Gastrectomy With Lymph Node Dissection for Gastric Cancer (KLASS-06)
Although Laparoscopic gastrectomy for both early and locally advanced gastric cancer has gained popularity, the use of laparoscopic total gastrectomy for proximal advanced gastric cancer is still limited to some experienced…
- Trial name
- NCT03385018
- Testing
- Radical total gastrectomy with D2 (D2 - #10) lymph node dissection by laparoscopic approach, Radical total gastrectomy with D2 (D2 - #10) lymph node dissection by open conventional approach
- Where
- South Korea
- Volunteers
- 772 people
- Sponsor
- Yonsei University
Stomach Neoplasm
Laparoscopic vs. Open Distal Gastrectomy After Neoadjuvant Chemotherapy
The study was designed as single-country, multi-center, open-labelled, randomized (1:1), phase II trial. 238 patients with medically and technically operable advanced gastric adenocarcinoma in middle or distal 1/3 of stomach are…
- Trial name
- NCT04658589
- Testing
- Laparoscopic versus open distal gastrectomy
- Volunteers
- 238 people
- Sponsor
- Chonnam National University Hospital
Bariatric Surgery, Lidocaine
Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy
Although laparoscopic (LAP) bariatric surgery is minimally invasive. Following any laparoscopic procedure, patients typically experience the peak of postoperative pain within the first 24 hours.
- Conditions
- Bariatric Surgery, Lidocaine, Dexmedetomidine
- Trial name
- NCT07327905
- Testing
- intravenous lidocaine, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Gastric Cancer, Adenocarcinoma of Esophagogastric Junction
A Prospective Study on Esophagogastrostomy by an Innovative Surgical Technique
This is a single-center, open-label, Phase Ib/II study aiming to assess the perioperative safety and postoperative outcomes of a novel surgical technique in treating primary adenocarcinoma located in the upper 1/3 of the stomach…
- Trial name
- NCT06300879
- Testing
- Performing totally laparoscopic proximal gastrectomy with esophagogastrostomy by fissure technique
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huashan Hospital
Postoperative Nausea and Vomiting, Postoperative Pain After Laparoscopic Sleeve Gastrectomy
Paragastric Block for Pain and PONV in Sleeve Gastrectomy
This single-center, prospective, randomized, double-blind controlled trial aims to evaluate the effects of intraoperative paragastric block (PGBLOCK) on early postoperative visceral pain, postoperative nausea and vomiting (PONV)…
- Trial name
- BLOCK-SG (NCT07274215)
- Testing
- Bupivacaine 0.5%, Isotonic Saline (0.9% NaCl)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Umraniye Education and Research Hospital
Proximal Early Gastric Cancer
The Anti-reflux Effect of Double-flap Technique in Laparoscopic Proximal Gastrectomy.
This study is a multicenter, open-label, prospective, randomized parallel-controlled trial. The purpose is to explore whether the incidence rate of reflux esophagitis (RE) within 12 months after surgery is non-inferior for the…
- Trial name
- NCT06511609
- Testing
- double-flap technique（DFT）; double-tract reconstruction(DTR),
- Volunteers
- 244 people
- Sponsor
- Changzhi People's Hospital Affiliated to Changzhi Medical College
Postoperative Pain
External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative Pain in Laparoscopic Radical Gastrectomy
Postoperative pain is highly prevalent following laparoscopic radical gastrectomy. Although Transversus abdominis plane block combined with rectus sheath block(TAP+RSB） can effectively alleviate this pain, it still has many…
- Trial name
- NCT07496086
- Testing
- EOIB, TAP+RSB
- Where
- China
- Volunteers
- 100 people
- Sponsor
- General Hospital of Ningxia Medical University
Obesity, Morbid
Laparoscopic Single Anastomosis Sleeve Ileal Bypass Versus Laparoscopic Sleeve Gastrectomy for Morbid Obesity
This study will compare two bariatric surgical interventions in terms of weight loss, gastroesophageal reflux, and effects on obesity-related comorbid conditions in morbidly obese patients.
- Trial name
- NCT05611697
- Testing
- Single anastomosis sleeve ileal bypass, Sleeve gastrectomy
- Where
- 2 sites in Norway
- Volunteers
- 220 people
- Sponsor
- Oslo University Hospital