Clinical trials: Laparoscopic Gynecologic Surgery
Post Operative Pain, Gynecologic Cancer
Pilot: Intraoperative TAP Block and Post-operative Pain Control for Minimally Invasive Hysterectomy for Endometrial Cancer
Modern postoperative pain management aims to optimizing pain relief while minimizing opiate usage. While opiates are effective for pain relief, they result in common adverse effects such as nausea, constipation, and urinary…
- Trial name
- NCT05763667
- Testing
- Liposomal bupivacaine, Bupivacain
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Tufts Medical Center
Mechanical Power, Postoperative Pulmonary Complications (PPCs)
EIT vs Dynamic Compliance Guided PEEP Titration During Laparoscopic Gynecological Surgery
The goal of this randomized controlled clinical trial is to compare the pulmonary protective effects of two different positive end-expiratory pressure (PEEP) titrating methods in patients with non-injured lungs undergoing…
- Conditions
- Mechanical Power, Postoperative Pulmonary Complications (PPCs), Oxygenation
- Trial name
- TITRANT (NCT07170514)
- Testing
- EIT-guided PEEP titration, Cdyn-guided PEEP titration
- Where
- 3 sites in Hungary
- Volunteers
- 200 people
- Sponsor
- Pest County Flór Ferenc Hospital
Ovarian Cancer, Cervical Cancer
A Prospective Study to Evaluate the Clinical Performance and Safety of the SIRIUS Endoscope System in Laparoscopic Gynecological Surgery.
Precision Robotics' Sirius Robotic Flexible Endoscopic System is a new fully integrated compact 3D laparoscopic camera system with a disposable single-use flexible tip that can change its viewing direction.
- Conditions
- Ovarian Cancer, Cervical Cancer, Gynecologic Cancer
- Trial name
- NCT05318625
- Testing
- Gynaecological laparoscopic surgery (Sirius System)
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Precision Robotics (Hong Kong) Limited
Gynecological; Surgery (Previous), Affecting Fetus, Postoperative Pain
Mü-opioid Receptor Level and Postoperative Pain in Patients With Gynecological Laparoscopy
The hypothesis that gonadal hormones may affect the perception of pain is an interesting research area. This prospective observational study will undergo elective laparoscopic gynecological surgery to 18-65 years, is planned to…
- Trial name
- NCT04690491
- Testing
- follicular cyclus, luteal cyclus
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bozok University
Gynecological Disease
Improved Rehabilitation After Surgery and Hypnosis: Benefits Potentiated by a Preoperative Consultation
Today, patient management in the context of scheduled surgery must meet new requirements. The understanding of surgical aggression, the evolution of anesthesia and surgery techniques have allowed the birth of the protocol of…
- Trial name
- RACHYP (NCT05276882)
- Testing
- Hypnosis, pre-surgery consultation
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Opioid Substitution Treatment
ICE-T Pain Regimen for Total Laparoscopic Hysterectomy
The purpose of this randomized controlled trial is to determine whether, "ICE-T," a multimodal postoperative pain regimen composed of around the clock ice packs, toradol, and tylenol, has improved pain control compared to the…
- Trial name
- NCT03987022
- Testing
- Ketorolac, Opioids, Ice Packs
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- MetroHealth Medical Center
Pain, Postoperative
Pre-emptive Local Anaesthesia in Gynecological Laparoscopy
Pre-emptive local anaesthetics are widely used in laparoscopic surgery, but there is no really consistent evidence that it is useful. Studies in the literature have shown contradicting results.
- Trial name
- NCT01677143
- Testing
- Bupivacaine 5mg/ml
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Atelectasis
Lung Ultrasound Evaluation of Individualized Versus Standard PEEP on Postoperative Atelectasis in Gynecological Laparoscopy
The purpose of this study is to compare two different airway pressure (PEEP) strategies during gynecological laparoscopic surgery to see which one better prevents lung collapse (atelectasis).
- Trial name
- NCT07602543
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara Etlik City Hospital
Laparoscopic Gynecologic Surgery
Utilizing Telemedicine for Delivery of Postoperative Care
The investigators propose a pilot project in which enrolled patients undergoing major gynecologic surgery will be randomized to either a traditional office postoperative visit or a telemedicine postoperative visit.
- Trial name
- Telemedicine (NCT04348357)
- Testing
- Telemedicine, Office visit
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Gynecological Laparoscopy
The Effect of Kinesio Tape on Pain Management in Laparoscopic Gynecological Surgeries.
Kinesio tapes have been used in medicine to reduce pain in various situations. It is an easy applicable and effective tape. The possible affect of this tape will be assessed in patients undergoing gynecological laparoscopic…
- Trial name
- NCT06648811
- Testing
- Pain management after surgery
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Mersin University
Shoulder Pain, Laparoscopic Surgery
Reducing Shoulder Tip Pain Following Laparoscopic Surgery
Laparoscopic surgery is becoming a major procedure, owing to smaller incisions, shorter hospitalizations, and less post-operative pain as compared with traditional laparotomies.
- Trial name
- NCT01135836
- Testing
- Pulmonary recruitment maneuver, Intraperitoneal normal saline, Control group
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Pelvic Organ Prolapse (POP), Synthetic Mesh
Safety and Performance of a Pelvic Floor Mesh Implant for Laparoscopic Sacrocolpopexy (ProGYNious)
The purpose of this clinical investigation is to collect clinical data about the ProGYNious Mesh based on a prospective clinical investigation.
- Conditions
- Pelvic Organ Prolapse (POP), Synthetic Mesh, Laparoscopic Surgery, Gynecologic Laparoscopic Surgery
- Trial name
- ProGYNious (NCT07497321)
- Testing
- Surgical mesh for pelvic organ prolapse repair (ProGYNious)
- Where
- 5 sites in Austria, Germany
- Volunteers
- 100 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Postoperative Nausea and Vomiting
Dose-ranging Study of Ramosetron for the Prevention of Nausea and Vomiting After Gynecologic Laparoscopic Surgery
Many patients receiving opioid based analgesia after gynecologic laparoscopic surgery experience postoperative nausea and vomiting (PONV) despite prophylaxis and treatment with HT3 receptor antagonists.
- Trial name
- NCT02478645
- Testing
- ramosetron 0.3, ramosetron 0.45, ramosetron 0.6
- Where
- South Korea
- Volunteers
- 177 people
- Sponsor
- Yonsei University
Laparoscopic Surgery, Intraoperative Hypothermia
Predicting Hypothermia in Gynecological Laparoscopic Surgery Using Machine Learning
Brief Title: Predicting Hypothermia in Gynecological Laparoscopic Surgery Using Machine Learning Brief Summary: This study aims to develop and validate a machine learning model for predicting intraoperative hypothermia (IOH) in…
- Conditions
- Laparoscopic Surgery, Intraoperative Hypothermia, Gynecological Surgery
- Trial name
- NCT07353528
- Where
- 4 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Postoperative Complications, Postoperative Gastrointestinal Dysfunction (POGD)
Abdominal Acupuncture for Gastrointestinal Function Recovery After Gynecologic Laparoscopic Surgery
Current research on the role of abdominal acupuncture in promoting postoperative gastrointestinal recovery remains limited, characterized by a lack of large-scale, standardized clinical trials, particularly with respect to…
- Conditions
- Postoperative Complications, Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus
- Trial name
- NCT07293026
- Testing
- Abdominal acupuncture, Standard postoperative management protocol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Mengyao Han
Postoperative Pain
Postoperative Analgesia in Laparoscopic Gynecological Surgeries
The aim of this study is to compare intraperitoneal instillation of magnesium sulfate versus sodium bicarbonate as an adjuvant to lidocaine 1% , on reducing postoperative pain in laparoscopic gynecological surgeries.
- Trial name
- NCT06491485
- Testing
- Group M (lidocaine with Magnesium sulfate), Group B (lidocaine with Sodium bicarbonate), Group C (lidocaine with saline)
- Volunteers
- 90 people
- Sponsor
- Assiut University
Influence of Perioperative Fluid Regime on Intraocular Pressure During Laparoscopic Gynecologic Surgery
Influence of Perioperative Fluid Management on Intraocular Pressure During Hynecologic Laparoscopic Pelvic Surgery
The aim of this study was to quantify the Intraocular Pressure (IOP) changes in patients undergoing laparoscopic hysterectomy at different time points and body positions throughout the procedure, and to explore the influence of…
- Trial name
- NCT01676064
- Testing
- ringer lactate solution, restrictive fluid regime
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Ziv Hospital
Myomas, Ovary Cysts
The Efficacy and Safety Study of a New Cross-linked Hyaluronan Hydrogel in the Reduction of Postsurgical Peritoneal Adhesions
The purpose of this study was to determine whether the new crosslinked hyaluronan hydrogel was safe to use, and was effective for the prevention/reduction of adhesion formation following gynecological surgery
- Conditions
- Myomas, Ovary Cysts, Endometriotic Cysts, Adhesions
- Trial name
- BAP (NCT02166554)
- Testing
- Saline, Cross-linked Hyaluronan Hydrogel
- Where
- 7 sites in China
- Volunteers
- 216 people
- Sponsor
- BioRegen Biomedical (Changzhou) Co., Ltd
Airway Morbidity, Anaesthesia
I-gel vs LMA Supreme in Laparoscopic Gynecological Surgery
To compare the effects of i-gel and Laryngeal mask airway Supreme (LMA-Supreme) on ventilation parameters and surgical view during Trendelenburg Position laparoscopic gynecological surgery in cases administered positive pressure…
- Trial name
- NCT02923427
- Testing
- Laryngeal mask Supreme Evaluation, i-gel Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Dokuz Eylul University
Infection Secondary to Surgical Procedure
Antibiotic Prophylaxis in Gynecologic Laparoscopy
Laparoscopy is a surgical procedure indicated for most gynecological pathologies and presents numerous advantages over laparotomy, among them lower rates of surgical site infection and less comorbidity feverish.
- Trial name
- NCT01991834
- Testing
- gynecologic laparoscopy, Cefazolin
- Where
- 2 sites in Brazil
- Volunteers
- 114 people
- Sponsor
- Universidade do Vale do Sapucai