Clinical trials: Laparoscopic Gynecological Surgical Procedures
to Determine Whether Patient Satisfaction With Postoperative Telehealth Follow-up is Non-inferior to In-person Clinic Visits
Outpatient Visits Versus Telehealth for Postoperative Care After Minimally Invasive Gynecologic Surgery
Telehealth, or telemedicine, utilizes technology to deliver clinical care remotely, either in real time or asynchronously, between clinician and patient.
- Trial name
- Telehealth RCT (NCT07420114)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Colon Disease, Gynecologic Disease
Optic Nerve Sheath Diameter in Laparoscopic Surgeries During Trendelenburg Position
It is difficult to measure the several levels of intracranial pressure during abdominal surgery, and direct monitoring with intracranial devices is often impossible.
- Trial name
- NCT04428229
- Testing
- Optic nerve sheath diameter
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Respiratory Mechanics, Hemodynamics
vNOTES vs Laparoscopy: Respiratory Mechanics and Hemodynamics
Pneumoperitoneum and Trendelenburg position are unavoidable in laparoscopic surgery and are known to have adverse effects on intraoperative respiratory mechanics and hemodynamics.
- Trial name
- NCT07667907
- Testing
- vNOTES (Vaginal Natural Orifice Transluminal Endoscopic Surgery, Laparoscopic Gynecological Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Laparoscopic Gynecological Surgical Procedures
Clinical Validation Study of the Eximis CS (Contained Segmentation) System
The purpose of this study is to evaluate device safety and effectiveness of the Eximis CS System.
- Trial name
- NCT06572163
- Testing
- Eximis CS (Contained Segmentation) System
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Eximis Surgical
Patients Who Were Scheduled for General and Gynecological Laparoscopic Procedures
Evaluation of the Follow Me Mode of the AutoLap System - A Feasibility Study
The main objectives of this study are to evaluate the performance and ease of use of the Follow me mode of the AutoLap system during general and gynecological laparoscopic procedures.
- Trial name
- NCT02326870
- Testing
- AutoLap
- Where
- 4 sites in Israel, Netherlands
- Volunteers
- 33 people
- Sponsor
- M.S.T. Medical Surgery Technology LTD.
Laparoscopic Gynecological Surgery
Effect of Intrathecal Morphine on Quality of Recovery After Laparoscopic Gynecological Surgery
Minimally invasive gynecologic surgery has become the standard approach for the treatment of benign and malignant gynecologic diseases, offering the advantages of reduced surgical trauma and faster recovery.
- Trial name
- NCT07322029
- Testing
- Intrathecal morphine group, TAPB, Intrathecal saline injection
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Sun Yat-sen University
Pelvic Pain, Endometriosis
Postoperative Narcotic Use After Laparoscopic Gynecologic Surgery
This will be a prospective, randomized, double blinded placebo-controlled study at Erlanger hospital. Eligible patients who provide consent will be randomized into one of two arms receiving continuous intra-peritoneal local…
- Conditions
- Pelvic Pain, Endometriosis, Pelvic Prolapse
- Trial name
- NCT04118777
- Testing
- Ropivacaine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Tennessee, Chattanooga
Gynecologic Surgical Procedures, Postoperative Nausea and Vomiting (PONV)
Oliceridine on Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery
The aim of this clinical trial is to evaluate the impact of the analgesic Oliceridine on postoperative nausea and vomiting (PONV) following gynecological laparoscopic surgery.
- Conditions
- Gynecologic Surgical Procedures, Postoperative Nausea and Vomiting (PONV), Laparoscopy
- Trial name
- NCT07026162
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 96 people
- Sponsor
- YanYing Xiao
Laparoscopic Gynecological Surgery
Analgesic Effect of Pulmonary Recruitment and Intraperitoneal Hydrocortisone in Laparoscopic Gynecological Surgery
The aim of this study is to compare the postoperative analgesic efficacy of intraperitoneal hydrocortisone to pulmonary recruitment maneuver in Laparoscopic gynaecological surgery.
- Trial name
- NCT03845608
- Testing
- Pulmonary Recruitment Maneuver
- Volunteers
- 45 people
- Sponsor
- Cairo University
Anesthesia, Intravenous, Hemodynamic Stability
Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery
This single-center study at CHA Ilsan Medical Center compares intraoperative hemodynamics between remimazolam- and propofol-based total intravenous anesthesia (TIVA) in patients undergoing robot-assisted gynecologic surgery…
- Conditions
- Anesthesia, Intravenous, Hemodynamic Stability, Gynecologic Surgery
- Trial name
- By_HD (NCT07251101)
- Testing
- Remimazolam, Propofol
- Where
- 2 sites in South Korea
- Volunteers
- 58 people
- Sponsor
- Ilsan Cha hospital
Surgery, Surgery in Early Childhood
The Asensus Paediatric Robotic Registry
An open-label, observational, paediatric registry trial in which participating centers enroll subjects who had or will have a laparoscopically-assisted surgery using the Senhance Surgical System.
- Trial name
- miniTRUST (NCT07081828)
- Testing
- Surgery
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- Asensus Surgical
Surgery, Laparoscopic
Low Versus Standard Pressure Pneumoperitoneum on Shoulder Tip Pain
This proposed study is a single-center, double blind, parallel group RCT comparing the use of low (10 mm Hg) versus standard pressure (15 mm Hg) pneumoperitoneum at the time of benign gynecologic laparoscopic surgery.
- Conditions
- Surgery, Laparoscopic, Laparoscopy, Penumoperitoneum
- Trial name
- NCT06504277
- Testing
- Low Pressure Penumoperitoneum, Standard Pressure Group (No intervention- active comparator)
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Gynecologic Diseases
Effective Maneuver for Post-laparoscopic Shoulder Pain
The aim of this clinical trial is to estimate the efficacy and safety of combined intervention with the intra-peritoneal normal saline instillation and pulmonary recruitment maneuver for reducing post-laparoscopic shoulder pain.
- Trial name
- NCT02811081
- Testing
- Passive Deflation, Normal Saline Instillation, Normal Saline Instillation + Pulmonary Recruitment
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Kangbuk Samsung Hospital
Pulmonary Atelectasis
Ultrasound-guided Alveolar Recruitment in Laparoscopic Gynecological Surgery
The study aims to compare the degree of atelectasis between ultrasound-guided alveolar recruitment group and conventional alveolar recruitment group in patients receiving laparoscopic gynecologic surgery
- Trial name
- NCT03607240
- Testing
- lung ultrasound-guided alveolar recruitment, conventional alveolar recruitment
- Where
- 2 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Laparoscopic Gynecological Surgery
EEG and ANI Guided Anesthesia and Quality of Recovery
This study aims to assess whether electroencephalogram (EEG) and nociception level-guided anesthesia can improve quality of recovery after laparoscopic gynecological surgery compared with standard care.
- Trial name
- NCT05936671
- Testing
- EEG-and-ANI-guided anesthesia, standard anesthesia, Sevoflurane and remifentanil
- Where
- 2 sites in South Korea
- Volunteers
- 126 people
- Sponsor
- Gangnam Severance Hospital
Surgery
Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery
Prospective, open-label clinical trial to evaluate the efficacy and safety of andexanet alfa patients who require urgent surgery that have been anticoagulated with the FXa (activated factor X) inhibitors.
- Trial name
- Annexa-S (NCT04233073)
- Testing
- andexanet alfa
- Where
- 56 sites in United States, Austria and 4 more
- Volunteers
- 10 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Anesthesia, Gynecologic Cancer
The Effects of VC Versus PC Ventilation on Cerebral and Respiratory Parameters in Patients Undergoing Laparoscopic Gynecologic Surgery
The aim of the study was to determine whether the use of different mechanical ventilation modes in patients with Trendelenburg position and CO2 insufflation affects respiration and cerebral oxygenation due to postoperative…
- Conditions
- Anesthesia, Gynecologic Cancer, Mechanical Ventilation Complication
- Trial name
- NCT06482983
- Testing
- Mechanical Ventilation Mode
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Umraniye Education and Research Hospital
Cervical Cancer, Uterus Cancer
Perioperative Morbidity in Gyneco-oncology According to the Procedure : Coelioscopy Versus Robot-assisted Coelioscopy
The purpose of this study is to compare perioperative morbidity of coelioscopy versus robot-assisted coelioscopy in cervical cancer, uterus cancer and ovarian cancer.
- Conditions
- Cervical Cancer, Uterus Cancer, Ovarian Cancer
- Trial name
- ROBO-GYN (NCT01247779)
- Testing
- gynecologic surgery - standard coelioscopy, gynecologic surgery - robot assisted coelioscopy
- Where
- 17 sites in France
- Volunteers
- 386 people
- Sponsor
- Centre Oscar Lambret
Gynecologic Cancer
Laparoscopic Ultra-radical Lymph Node Debulking Using Yasargil Clamps (Yasargil-1)
Although several studies have demonstrated the overall benefits of a laparoscopic approach for pelvic and para-aortic lymphadenectomy, complications remain a challenging scenario.
- Trial name
- NCT05318170
- Testing
- Laparoscopic ultra-radical lymph node debulking
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- University of Palermo
Postoperative Nausea and Vomiting, Gynecologic Surgical Procedures
Triple Therapy of Dexamethasone, Palonosetron, and Fosaprepitant As PONV Prevention
As a preventive for postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery, the investigators shall investigate the efficacy of the triple therapy of dexamethasone, palonosetron, and…
- Conditions
- Postoperative Nausea and Vomiting, Gynecologic Surgical Procedures, Laparoscopy
- Trial name
- NCT05773950
- Testing
- fosaprepitant, normal saline
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Samsung Medical Center