Clinical trials: Laparoscopic Myomectomy
Laparoscopic Myomectomy
Effects of Different Ventilation Modes on Airway Pressure and Intracranial Pressure in Patients in the Trendelenburg Position
The goal of this clinical trial is to understand the impact of three different ventilation modes-pressure-controlled ventilation (PCV), volume-controlled ventilation (VCV), and pressure-regulated volume-controlled ventilation…
- Trial name
- PCV、VCV、PRVC (NCT06665061)
- Testing
- PCV, VCV, PRVC
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Inner Mongolia Baogang Hospital
Leiomyoma, Laparoscopy
Combined Vaginal Misoprostol and Perivascular Vasopressin
Injection of Vasopressin into the uterine tissue surrounding fibroids constricts blood vessels, and has been found to be beneficial by decreasing blood flow to fibroids, and thereby resulting in less bleeding with removal.
- Conditions
- Leiomyoma, Laparoscopy, Uterine Myomectomy
- Trial name
- NCT03815344
- Testing
- Standard, Standard-vaginal misoprostol
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Antonios Likourezos
Anesthesia, Myomectomy
Improved Recovery Using Multimodal Peri-operative Analgesia in Minimally Invasive Myomectomy
The purpose of this study is to evaluate a multimodal analgesic protocol used in minimally invasive surgery for myomectomies (laparoscopic myomectomy (LM) and laparoscopically assisted myomectomy (LAM)).
- Trial name
- NCT00978601
- Testing
- Multimodal analgesic protocol during minimally invasive myomectomy
- Where
- Greece
- Volunteers
- 95 people
- Sponsor
- Iakentro Fertility Centre
Uterine Fibroids
Single-channel Fibroid Morcellation System Used in Clinical Research on Laparoscopic Myomectomy
This prospective, single-center, randomized, single-blind controlled trial aims to evaluate the efficacy and safety of a novel single-channel retrieval bag compared to a widely used dual-channel retrieval bag in laparoscopic…
- Trial name
- NCT07512973
- Testing
- Single-channel specimen retrieval bag, Double-channel specimen retrieval bag
- Volunteers
- 78 people
- Sponsor
- First People's Hospital of Hangzhou
Surgery
LapBox® Manual Containment System
This study to evaluate the leak integrity of the LapBox Manual Containment System for laparoscopic hysterectomy and myomectomy. The goal is to determine the integrity of this containment system in order to increase surgical…
- Trial name
- NCT07767968
- Testing
- LapBox Manual Containment System, Standard of Care Specimen Bag
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Wisconsin, Madison
Myoma;Uterus, Adenomyoma of Uterus
Evaluation of the Feasibility of Using Augmented Reality in Laparoscopic Surgery, by a Clinical Study During Gynecological Laparoscopic Surgical Procedures.
Augmented Reality is a technology that allows surgeons to superimpose virtual images from preoperative imaging onto the endoscopic vision system intraoperatively.
- Trial name
- ENDORA2 (NCT06067971)
- Testing
- Laparoscopic surgery with augmented reality device
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Myoma
Laparoscopic Enclosed Morcellation; Electromechanic Morcellation vs Vaginal Removal
Laparoscopic tissue removal is one of the most challenging parts for the laparoscopic surgery. For this reason, electromechanical morcellation has long been used to facilitate the tissue removal in gynecology.
- Trial name
- NCT02737553
- Testing
- Enclosed morcellation, vaginal morcellation
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Ege University
Myoma
Prevention of Intra-uterine Adhesions Following Laparoscopic and Laparotomic Myomectomy
Clinical study on the prevention of intrauterine adhesions after laparoscopic or laparotomic myomectomy. Myomas are common in women of reproductive age and myomectomy can lead to intra-uterine adhesions, which can be detrimental…
- Trial name
- PALLM (NCT05683041)
- Testing
- Hyalobarrier
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Oxytocin, Hemodynamic Monitoring
Effects of Oxytocin on Hemodynamics in Patients Undergoing Laparoscopic Myomectomy
This project will study the effect of oxytocin on hemodynamics in patients undergoing laparoscopic myomectomy, and how to prevent and manage such hemodynamic changes effectively.It provides a reference for the rational use of…
- Conditions
- Oxytocin, Hemodynamic Monitoring, Laparoscopic Surgery
- Trial name
- NCT04109339
- Testing
- Oxytocin
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Laparoscopic Myomectomy, Quadratus Lumborum Nerve Block
Quadratus Lumborum Nerve Blocks for Myomectomies
This study would like to compare the use of the current standard of care in pain management for patients undergoing laparoscopic myomectomies to the addition of a quadratus lumborum nerve block plus the standard of care.
- Trial name
- NCT03935815
- Testing
- Ropivacaine injection
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles
Fibroids
Barbed Suture Versus Traditional Suture Material for Laparoscopic Myomectomy
The objective of this study is to determine if the use of a new type of barbed suture material for laparoscopic myomectomy (surgical removal of fibroids) versus the traditional approach of suturing with conventional suture…
- Trial name
- NCT01347385
- Testing
- Laparoscopic myomectomy with unidirectional barbed suture, Traditional suture material
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cosmetic Outcomes
Single Port Myomectomy Versus Conventional Myomectomy
This study is about the evaluation of which benefits single port laparoscopic myomectomy has in the perspective of cosmetics and patient satisfaction.
- Trial name
- SM (NCT01826578)
- Testing
- using only one port for laparoscopic surgery
- Where
- South Korea
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Laparoscopic Myomectomy
The Effect of Intramyometrial Injection of Terlipressin Versus Intramyometrial Injection of Carbitocin on Hemoglobin and Blood Loss During Laparoscopic Myomectomy Operations
Our study aims to evaluate the efficacy of intramyometrial injection of Terlipressin versus intramyometrial injection of Carbetocin on hemoglobin level in women undergoing abdominal myomectomy.
- Trial name
- NCT05154279
- Testing
- Terlipressin
- Where
- 2 sites in Egypt
- Volunteers
- 99 people
- Sponsor
- Wael Elbanna Clinic
Laparoscopic Myomectomy
Temporary Uterine Tourniquet Application Versus Local Myometrial Epinephrine Injection During Laparoscopic Myomectomy
While both local vasoconstrictors and tourniquet application are recognized methods for blood loss control, there is a paucity of head-to-head randomized controlled trials directly comparing these two distinct approaches in…
- Trial name
- NCT07525687
- Testing
- Temporary Uterine Tourniquet Application, Local Myometrial Epinephrine Injection
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Minia University
Leiomyoma
Power Morcellation Systems for Laparoscopic Hysterectomy and Myomectomy
The purpose of this study is to determine the safety and efficacy of insufflated bags for electromechanical power morcellation during laparoscopic hysterectomy and myomectomy for tissue removal and to observe the integrity of the…
- Trial name
- NCT02777203
- Testing
- EcoSac 400 ECO-T
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Uterine Leiomyoma, Surgical Procedure, Unspecified
Comparison Between Robotic (RM) and Laparoscopic Myomectomy (LM)
This is a single-blinded RCT evaluating the effect of robotic-assisted (RM) or conventional laparoscopic surgery (LM) in the management of uterine leiomyomas.
- Trial name
- NCT04282863
- Testing
- RM, LM
- Where
- Taiwan
- Volunteers
- 494 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Myoma
Safety and Efficacy Study of a Hydrogel, Applied Following Removal of Myomas During Gynecologic Surgery, Administered for the Prevention/Reduction of Postoperative Adhesion Formation
The purpose of this study was to determine whether the adhesion prevention gel was safe to use, and was effective for the prevention/reduction of adhesion formation that typically occurs following gynecological surgery to remove…
- Trial name
- NCT00562471
- Testing
- Adhibit Adhesion Prevention Gel, Standard of Care Comparator
- Where
- 6 sites in Canada, Germany and 1 more
- Volunteers
- 76 people
- Sponsor
- Angiotech Pharmaceuticals
Uterine Fibroids (Leiomyoma), Myomectomy
Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy
The current study is a multiple-arm, single blinded, and controlled randomized trial. It will be conducted in two gynecological endoscopy centers: • ElShatby University Hospital, a tertiary level hospital in Alexandria, Egypt.
- Conditions
- Uterine Fibroids (Leiomyoma), Myomectomy, Myomectomy; Surgical Blood Loss
- Trial name
- NCT07352761
- Testing
- Temporary clipping of uterine artery, Temporary occlusive suturing of uterine artery, Bipolar coagulation of uterine arteries
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Pain, Hysterectomy
Ultravision Visual Clearing System in Laparoscopic Hysterectomy and Myomectomy
This is a prospective blinded, randomized controlled study. The study will include three study arms: Patients undergoing laparoscopic hysterectomies will be randomized to one of either "Ultravision" (study arm 1) or "no…
- Conditions
- Pain, Hysterectomy, Myomectomy
- Trial name
- NCT03634306
- Testing
- Ultravision System, Laparoscopic Hysterectomy
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Mercy Research
Uterine Myoma
Surgical Outcome of Two-port Laparoscopic Myomectomy
Study Objective: To evaluate the surgical outcome of laparoendoscopic two-sites myomectomy (LETS-M) and compare the difference between an experienced surgeon and three trainees. Design: A retrospective study.
- Trial name
- NCT04279626
- Testing
- LETS-M
- Where
- Taiwan
- Volunteers
- 204 people
- Sponsor
- National Taiwan University Hospital