Clinical trials: Laparoscopic Splenectomy
Cirrhosis, Splenectomy; Status
Effect of Laparoscopic Splenectomy on Renal Function in Cirrhotic Patients With Hypersplenism (2-Year Follow-Up)
Patients with liver cirrhosis often have impaired or at-risk kidney function due to the close link between liver and kidney (hepatorenal syndrome).
- Conditions
- Cirrhosis, Splenectomy; Status, Hypersplenism, Kidney Function Issue
- Trial name
- LS-RF (NCT07585773)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Northern Jiangsu People's Hospital
Portal Vein Thrombosis, Splenic Vein Thrombosis
Anticoagulation Post Laparoscopic Splenectomy
Splenic/portal vein thrombosis is an alarming complication of splenectomy. Retrospective studies in the literature have shown the incidence of symptomatic splenic/portal vein thrombosis to be between 0.7% (Rattner et al., 1993)…
- Trial name
- NCT00769873
- Testing
- Enoxaparin
- Where
- 2 sites in Canada
- Volunteers
- 35 people
- Sponsor
- University of Alberta
Lipid Profiles, Cirrhosis, Liver
Effect of LSD on Lipid Profiles Within 1 Year Postoperatively in Cirrhosis Patients With Portal Hypertension Bleeding
Patients with liver cirrhosis frequently exhibit dyslipidemia due to impaired hepatic lipid synthesis, altered bile acid metabolism, and portal hypertension.
- Conditions
- Lipid Profiles, Cirrhosis, Liver, Portal Hypertension, Splenectomy; Status
- Trial name
- LSD-LPPH (NCT07811700)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Northern Jiangsu People's Hospital
Cirrhosis, Hypertension
Laparoscopic Splenectomy and Azygoportal Disconnection With Intraoperative Endoscopic Variceal Ligation
This study aimed to evaluate whether synchronous vagus nerve-preserving laparoscopic splenectomy and azygoportal disconnection with intraoperative endoscopic variceal ligation (SVEL) is effective and safe, and to determine…
- Conditions
- Cirrhosis, Hypertension, Splenectomy, Laparoscopy
- Trial name
- SVEL (NCT04244487)
- Testing
- laparoscopic splenectomy and azygoportal disconnection with intraoperative endoscopic variceal ligation
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Northern Jiangsu People's Hospital
Laparoscopic Splenectomy, Children
Laparoscopic Splenectomy in Children
Laparoscopic splenectomy (LS) gained popularity since it has been described for the first-time during nineties of past century. It has become "golden method" for splenectomy in all ages including children
- Conditions
- Laparoscopic Splenectomy, Children, Benign Blood Diseases
- Trial name
- splenectomy (NCT04763733)
- Testing
- laparoscopic splenectomy
- Volunteers
- 137 people
- Sponsor
- Tanta University
Cirrhosis, Liver, Splenectomy; Status
The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on the Immune Function for Cirrhosis Patients
In this study, the investigators compared the improvement of immune function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection.
- Trial name
- ELSDI (NCT05338294)
- Testing
- Laparoscopic splenectomy and azygoportal disconnection
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Northern Jiangsu People's Hospital
Cirrhosis, Liver, Splenectomy; Status
The Effect of Laparoscopic Splenectomy on the Immune Function for Cirrhosis Patients
In this study, the investigators compared the improvement of and azygoportal disconnection related indicators in patients with liver cirrhosis after laparoscopic splenectomy.
- Trial name
- ELSI (NCT05339269)
- Testing
- Laparoscopic splenectomy
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Northern Jiangsu People's Hospital
Cirrhosis, Splenectomy; Status
Effect of Laparoscopic Splenectomy on Lipid Profiles in Cirrhotic Patients With Hypersplenism (2-Year Follow-Up)
Patients with liver cirrhosis frequently exhibit dyslipidemia due to impaired hepatic lipid synthesis, altered bile acid metabolism, and portal hypertension.
- Conditions
- Cirrhosis, Splenectomy; Status, Hypersplenism, Lipid Profiles
- Trial name
- LS-LP-CH (NCT07588373)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Northern Jiangsu People's Hospital
Postoperative Pain
Prospective Randomized Comparison of Clinical Results of Hand Assisted Laparoscopic Splenectomies and Open Splenectomies
ABSTRACT Background: Although there are some comparative studies between laparoscopy and hand-assisted laparoscopic splenectomy (HALS) in splenomegaly cases, there is no study of the differences between HALS and open splenectomy…
- Trial name
- NCT00754806
- Volunteers
- 27 people
- Sponsor
- Istanbul University
Cirrhosis, Liver, Splenectomy; Status
Effect of LSD on Renal Function in Cirrhotic Patients With Portal Hypertension
Patients with liver cirrhosis and portal hypertension often have impaired kidney function due to reduced blood flow to the kidneys and fluid buildup in the abdomen (ascites).
- Conditions
- Cirrhosis, Liver, Splenectomy; Status, Renal Function Abnormal, Portal Hypertension
- Trial name
- NCT07811713
- Testing
- Laparoscopic splenectomy and azygoportal disconnection
- Volunteers
- 496 people
- Sponsor
- Northern Jiangsu People's Hospital
Cirrhosis, Hypertension
Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy
The purpose of this study is to determine whether Warfarin Anticoagulation are effective and safe in Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients with Hypersplenism after Laparoscopic Splenectomy.
- Conditions
- Cirrhosis, Hypertension, Venous Thrombosis, Status; Splenectomy
- Trial name
- ESWA (NCT02238444)
- Testing
- Warfarin, Dipyridamole, Aspirin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yangzhou University
Cirrhosis, Hypertension
Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection
The purpose of this study is to determine whether Warfarin Anticoagulation are effective and safe in Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients after Laparoscopic Splenectomy and Azygoportal Disconnection…
- Conditions
- Cirrhosis, Hypertension, Status;Splenectomy, Venous Thrombosis
- Trial name
- ESWAPH (NCT02247414)
- Testing
- Warfarin, Dipyridamole, Aspirin
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Yangzhou University