Clinical trials: Laparoscopic Surgical Procedures
Surgery
Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery
Prospective, open-label clinical trial to evaluate the efficacy and safety of andexanet alfa patients who require urgent surgery that have been anticoagulated with the FXa (activated factor X) inhibitors.
- Trial name
- Annexa-S (NCT04233073)
- Testing
- andexanet alfa
- Where
- 56 sites in United States, Austria and 4 more
- Volunteers
- 10 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Cholecyctitis
Regional Cerebral Oxygen Saturation in Laparoscopic Surgery
While few studies have determined the optimal intra-abdominal CO2 insufflation pressure to achieve optimal surgical condition during LCs with deep-NMB and moderate-NMB in laparoscopic cholecystectomy (LC), previous studies…
- Trial name
- NCT02436954
- Testing
- CO2 insufflation at intra-abdominal pressure 8 mmHg, CO2 insufflation at intra-abdominal pressure 12 mmHg
- Volunteers
- 40 people
- Sponsor
- Konkuk University Medical Center
Pain, Postoperative
Fascial Closure Technique After Gynecologic Laparoscopic Surgery and Postoperative Pain
Our study aims to determine postoperative pain outcomes when comparing port site > 10 mm fascial closure with traditional direct closure versus use of laparoscopic fascial closure device in patients undergoing minimally invasive…
- Trial name
- NCT04765306
- Testing
- Traditional Direct Fascial Closure, Fascial Closure Device
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Jessica G Putman
Postoperative Nausea and Vomiting
Comparison of Different EtCO2 Levels in Preventing Postoperative Nausea and Vomiting
We aimed to evaluate the different ETCO2 levels (with the help of ultrasonographic optic nerve sheath diameter) in preventing gynecological laparoscopic surgeons' postoperative nausea induced by intracranial pressure change due…
- Trial name
- NCT03472209
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karadeniz Technical University
Laparoscopic Surgery
Short Title: Standard vs. Lower Pressure Pneumoperitoneum
This study aims to investigate the effect of varying insufflation pressures on post-operative pain and adequacy of surgical field visualization among patients undergoing laparoscopic surgery with a minimally invasive gynecologic…
- Trial name
- NCT06338865
- Testing
- Carbon dioxide, Bupivacaine, Oxycodone
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Cedars-Sinai Medical Center
Oncology
Evaluation of Low Flow and Normal Flow Anesthesia Management in Robotic Assisted Laparoscopic Surgeries
Robotic-assisted laparoscopic surgery has many advantages compared to conventional open surgery, such as less postoperative pain, shorter hospital stays, and faster recovery times.
- Trial name
- NCT06430593
- Testing
- low-flow anesthesia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Performance of Wrong Procedure (Operation)
Trial on Laparoscopic Simulation Based on Mentoring
More than 50 residents in surgical specialities (OB\&G, General surgery and Urology) from a single university in Italy will be randomized into two groups, after a stratification based on residency year and laparoscopic/simulator…
- Trial name
- NCT02486575
- Testing
- Self-learning, Mentoring
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Brescia
Hernia, Inguinal
Robotic Utility for Surgical Treatment of Groin Hernias
The purpose of this study is the measurement of the evolution of the operation time during the start-up phase of robotic-assisted surgery for the treatment of inguinal hernia's of 50 patients treated in Maria Middelares in…
- Trial name
- Robust _1 (NCT02975401)
- Testing
- rTAPP technique
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
UTERINE MYOMAS
Assessment of the Manageability and Safety of ADBLOCK Adhesion Barrier System in Laparoscopic Gynaecological Surgery
Adhesions are the most frequent complication of abdominopelvic surgery. They are internal scar tissues which form as a result of surgery which may abnormally join together what were once separate tissues and organs.
- Trial name
- ADBEE (NCT01745432)
- Testing
- ADBLOCK
- Where
- 3 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Terumo Europe N.V.
Postoperative Pain, Pelvic Pain
Interfascial Abdominal Wall Block for Gynecological Laparoskopy: A Randomized Clinical Trial
The purpose of this study is to evaluate the clinical efficacy of combining ultrasound-guided bilateral rectus sheath blocks (RSB) and quadratus lumborum blocks (QLB) compared to using a quadratus lumborum block alone for…
- Trial name
- NCT07705516
- Testing
- Bilateral QLB and RSB, Bilateral QLB alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Medical and Diagnostic Center "MEDION" LLC
Intracranial Pressure
The Effect of Pneumoperitoneum on Intracranial Pressure in Pediatric Laparoscopic Surgery: Ultrasonographic Measurement of Optic Nerve Sheath Diameter
The pneumoperitoneum during laparoscopic surgery in pediatrics has the potential to cause an increase of intracranial pressure (ICP).
- Trial name
- NCT01840267
- Testing
- ultrasonographic measurement of optic nerve sheath diameter
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Yonsei University
Neuromuscular Blockade
Effectiveness of Deep Versus Moderate Neuromuscular Blockade
The aim of this study is to evaluate the influence of depth of neuromuscular blockade during laparoscopic gastrectomy on postoperative pain in surgical patients allocated randomly to either deep or moderate neuromuscular blockade…
- Trial name
- NCT03266419
- Testing
- Deep NMB using rocuronium, Moderate NMB using rocuronium
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Liver Diseases, Liver Neoplasms
Classical Procedure Versus Intrahepatic Glisson's Approach
The purpose of this research is to compare the classical procedure with intrahepatic Glisson's approach for laparoscopic anatomical hepatectomy.
- Conditions
- Liver Diseases, Liver Neoplasms, Hepatic Haemangioma
- Trial name
- LAHIGA (NCT01567631)
- Testing
- intrahepatic Glisson's approach, classical hepatectomy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shuguo Zheng, MD
Stomach Neoplasms, Minimally Invasive Surgery
Intracorporeal Versus Extracorporeal Roux-en-Y Esophagojejunostomy During Laparoscopic Total Gastrectomy for Gastric Cancer
To date, Roux-en-Y esophagojejunostomy transabdominal extracorporeally by circular stapler was the most common used method during laparoscopy-assisted total gastrectomy for gastric cancer, even though it was not totally…
- Conditions
- Stomach Neoplasms, Minimally Invasive Surgery, Anastomosis
- Trial name
- NCT02085031
- Testing
- Intracorporeal Roux-en-Y esophagojejunostomy, Extracorporeal Roux-en-Y esophagojejunostomy
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Laparoscopic Surgeries
The Effect of Flow-controlled Ventilation on Hemodynamic and Respiratory Parameters in Laparoscopic Surgeries
It is aimed to investigate the effect of flow controlled ventilation on intraoperative respiratory parameters and hemodynamic parameters in laparoscopic operations.
- Trial name
- NCT06274372
- Testing
- flow controlled ventilation, volume controlled ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Derince Training and Research Hospital
Surgery, Laparoscopic, Sexual Dysfunction, Physiological
Bowel, Urinary and Sexual Function After Laparoscopic Colorectal Surgery
Research Populations: Male patients scheduled for laparoscopic colorectal surgery Study Method: Questionnaire and function tests Hypothesis: A laparoscopic nerve-sparing operation is not inferior to reported open surgery in…
- Conditions
- Surgery, Laparoscopic, Sexual Dysfunction, Physiological, Colorectal Surgery
- Trial name
- NCT00451165
- Testing
- laparoscopic colorectal surgery
- Where
- Japan
- Volunteers
- 36 people
- Sponsor
- Kyoto University
PEEP by Lung Ultrasound, PEEP With Dynamic Compliance
Postoperative Diaphragm Function in Pediatric Laparoscopic Abdominal Surgery Using Compliance and PEEP Guided by Lung Ultrasound
Protective ventilation strategies and alveolar recruitment maneuvers (ARM) are employed in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) to improve oxygenation, prevent alveolar collapse…
- Trial name
- NCT07126067
- Testing
- Lung Ultrasound and PEEP Application, Application of PEEP with Dynamic Compliance
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Konya City Hospital
Bariatric Surgery Candidate, Obesity, Morbid
Adolescents Bariatric Surgery Cohort Survey
Obesity affects 3%-4% of the pediatric population and leads to cardiac mortality during adult life. Bariatric surgery is the best treatment for weight loss and preventing obesity associated comorbidities in adults, but its…
- Conditions
- Bariatric Surgery Candidate, Obesity, Morbid, Obesity, Adolescent
- Trial name
- BariAdo (NCT04766801)
- Testing
- Laparoscopic adjustable gastric banding
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Medical Education
Generative AI-Assisted Personalized Feedback for Laparoscopic Skill Learning in Medical Undergraduates
Laparoscopic training involves learning to control surgical instruments while viewing movements on a screen. Feedback can help learners identify technical problems and plan further practice, but providing individualized guidance…
- Trial name
- AI-T-LAP (NCT07903467)
- Testing
- Generative AI-Assisted Personalized Feedback, Structured Template-Based Feedback
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yang Xiaodong
Peritoneal Metastases, Peritoneal Carcinomatosis
Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) has prolonged the survival substantially for selected patients with peritoneal metastases from colorectal cancer.Bleeding and thromboembolic disease…
- Conditions
- Peritoneal Metastases, Peritoneal Carcinomatosis, Colorectal Neoplasms Malignant, Intestinal Neoplasms
- Trial name
- CONTEST (NCT04744688)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.