Clinical trials: Laparoscopic Surgical Procedures
Pulmonary Pathology
Effect of Two Different Surgical Positions on Pulmonary Functions in Laparoscopic Gastrectomies
The primary purpose of the study is to investigate the effect of the 30° reverse trendelenburg position combined with the sunbed position on respiratory parameters in laparoscopic gastrectomies.
- Trial name
- NCT06402474
- Testing
- sunbed position
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istinye University
Laparoscopic Surgery, Pneumoperitoneum
Role of Individualized PEEP Vs Fixed PEEP in Mechanical Ventilation During Laparoscopic Surgeries
To compare the effects of Individualized positive end-expiratory pressure with recruitment maneuver on respiratory parameters and oxygenation in mechanical ventilation during laparoscopic surgeries with the fixed positive…
- Conditions
- Laparoscopic Surgery, Pneumoperitoneum, Positive End Expiratory Pressure (PEEP)
- Trial name
- NCT06929078
- Testing
- Protective lung ventilation methods with different positive end-expiratory pressure during Laparoscopic Surgeries
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Noor-Ul-Ain
PONV
Efficacy of IV Palo With IV Dexamethasone vs IV Palo for Prevention of Immediate & Delayed PONV
The purpose of this study is to determine if subjects who receive Palonosetron plus Dexamethasone have less post-operative nausea and vomiting (PONV) than those who receive Palonosetron alone.
- Trial name
- PONV (NCT00952133)
- Testing
- Palonosetron only, Palonosetron with Dexamethasone
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- NYU Langone Health
Residual Curarization
Residual Curarization and Its Incidence at Tracheal Extubation in China
This study will assess the residual neuromuscular blockade (NMB) Train-Of-Four (TOF) ratios at tracheal extubation when anesthesiologists have determined that full recovery of neuromuscular function has occurred using standard…
- Trial name
- RECITE-China (NCT01871064)
- Testing
- TOF-Watch SX® Monitoring of NMB
- Where
- 32 sites in China
- Volunteers
- 1,571 people
- Sponsor
- Xinmin Wu
Anastomosis; Complications, Anastomosis, Surgical
Role of Indexed Oxygen Delivery in Anastomotic Insufficiencies in Elective Laparoscopic Colorectal Resections for Cancer
Colorectal cancer is a very commonly diagnosed malignancy worldwide, and surgical resection remains the mainstay of treatment. Outcomes depend on preoperative staging, surgical quality, complication rates, and multidisciplinary…
- Conditions
- Anastomosis; Complications, Anastomosis, Surgical, Anastomosis, Leaking, Anastomotic Leaks
- Trial name
- NCT07099820
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Saint Camillus International University of Health Sciences
Morbid Obesity, Hernia
Minimally Invasive Surgery (MIS) Database for the Purpose of Research
The Minimally Invasive Surgery Team (MIST) are establishing a separate research database to find out more about patient's undergoing minimally invasive surgery (laparoscopic , open and robot assisted) procedures at UCSD.
- Conditions
- Morbid Obesity, Hernia, Colorectal Cancer, Laparoscopy
- Trial name
- NCT00535990
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Optic Nerve Sheath
The Effect of Pnemoperitoneum on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Surgery According to Anesthesia Agents: Propofol Based Total Intravenous Anesthesia vs Desflurane Anesthesia
The pneumoperitoneum during laparoscopic surgery have the potential to cause an increase of intracranial pressure (ICP). Previous studies have proposed that ultrasonographic measurements of the optic nerve sheath diameter (ONSD)…
- Trial name
- NCT02003768
- Testing
- Propofol, Desflurane
- Sponsor
- Yonsei University
LAPAROSCOPY, Sacrum; Anomaly
Per-operative Ultrasonographic Assessement of the Placement of the Mesh in Laparoscopic Sacral Colpo/Hysteropexy
This study is conducted in order to determinate the faisability of an intraoperative ultrasound to mesure the positioning of prostheses during laparoscopic promontofixation.
- Trial name
- SONOMESH (NCT03410303)
- Testing
- Intraoperative ultrasound and 2 months post-operative ultrasound ( ± 1 month)
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rectal Cancer, Surgery
Multicenter Study on Suprapubic Catheterization Versus Transurethral Catheterization in Laparoscopic Surgery for Rectal Cancer
Compared with traditional open proctectomy, laparoscopic surgery is associated with less pain, earlier recovery, and better cosmetic outcome, and its long-term oncologic outcomes have been demonstrated.
- Trial name
- MSSPC (NCT02728427)
- Testing
- Suprapubic catheterization using central venous catheter(CVC-2 7F), Transurethral catheterization using Foley catheter
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Hysterectomy, Laparoscopy
Tolerance of the vNOTES Surgical Technique in Total Hysterectomy for Benign Lesion. Clinical Trial of Non-inferiority Compared to the Laparoscopic Technique.
During a first consultation with an indication of total hysterectomy for a benign lesion, we will study the patient's eligibility.
- Conditions
- Hysterectomy, Laparoscopy, vNOTES
- Trial name
- VLAP (NCT05031182)
- Testing
- Laparoscopy, vNOTES
- Where
- 2 sites in France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Laparoscopic Surgical Procedures
Nano-Ceramic Coating for Laparoscope Lens
The investigator tests the effectiveness of nano-ceramic coating when applied (painted) on laparoscope lens to protect it from fogging or smearing during laparoscopic operations
- Trial name
- NCT03704259
- Testing
- Ceramic coating
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Zagazig University
Pneumoperitoneum, Neuromuscular Blockade
The Effect of Low Pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery on Innate Immune Homeostasis.
Substudy of the RECOVER trial (a randomised controlled trial comparing the effect of low pressure pneumoperitoneum with deep neuromuscular block versus normal pressure pneumoperitoneum with moderate neuromuscular block during…
- Conditions
- Pneumoperitoneum, Neuromuscular Blockade, Surgery, Immune Suppression
- Trial name
- RECOVER-PLUS (NCT03572413)
- Testing
- Low pressure pneumoperitoneum, Rocuronium bromide
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Laparoscopic Surgery
Assessment of the Wide Field of View Provided by the SurroundScope
The aim of this study is to assess the need and potential benefits of the wide field of view during general and gynecology laparoscopic surgery.
- Trial name
- NCT04651270
- Testing
- SurroundScope
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- 270Surgical
Morbid Obesity, Surgical Management by Laparoscopic Sleeve Gastrectomy
Kinematics of Obese Patients Perambulation
The aim of this study is to evaluate the consequences of sleeve gastrectomy on functional parameters of patients perambulation.
- Trial name
- MARCHOBESE (NCT01774682)
- Testing
- 6-minute walk test
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Endometriosis
Intraoperative Assessment of Ureteral Perfusion in Women With Endometriosis
Deep infiltrating endometriosis (DIE) is a severe form of endometriosis in which lesions affect retroperitoneal tissue and pelvic organs wall.
- Trial name
- NCT03950206
- Testing
- Indocyanine green angiography
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hernia, Inguinal, Laparoscopic Surgery
Progrip Versus ProFlor: Two Fixation Free Devices for Laparoscopic Inguinal Hernia Repair
there are currently two methods for fixation free laparoscopic inguinal hernia repair specifically based on the intrinsic properties of the device used.
- Trial name
- ProPro (NCT06556498)
- Testing
- Proflor group, Progrip group
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Palermo
Uterine Leiomyoma, Uterine Fibroid
ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma
A phase 3 multicenter unblinded randomized controlled trial comparing the temporary uterine blood supply occlusion with conventional approach during laparoscopic myomectomy in patients with uterine leiomyoma.
- Conditions
- Uterine Leiomyoma, Uterine Fibroid, Leiomyoma, Uterine, Myoma;Uterus
- Trial name
- NCT04519593
- Testing
- Laparoscopic myomectomy with prior temporary uterine blood supply occlusion, Conventional laparoscopic myomectomy
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Mother and Child Clinic Saint-Petersburg
Laparoscopic Surgery
The Impact of Anesthesia and Positioning on Cerebral Blood Flow and Pressure in Patients Undergoing Laparoscopic Surgery
The aim of this observational study was to understand the effect of ReverseTrendelenburg position, Trendelenburg position on intracranial pressure and carotid blood flow in patients undergoing laparoscopic surgery.
- Trial name
- NCT06669689
- Testing
- operating position, pneumoperitoneum
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiaguang Duan
Laparoscopy, Clinical Competence
Comparative Evaluation of Simulator Based and Traditional In-surgery Laparoscopic Camera Training's Efficiency in Novices
This prospective randomized study aims for determination whether focused simulator based laparoscopic camera training in novices can improve camera performance in an actual clinical situations in the same manner as traditional…
- Trial name
- NCT01092013
- Testing
- Training on laparoscopic simulator in skills lab, Training at actual laparoscopic surgery, Technical instruction
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Uterine Fibroids (Leiomyoma), Myomectomy
Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy
The current study is a multiple-arm, single blinded, and controlled randomized trial. It will be conducted in two gynecological endoscopy centers: • ElShatby University Hospital, a tertiary level hospital in Alexandria, Egypt.
- Conditions
- Uterine Fibroids (Leiomyoma), Myomectomy, Myomectomy; Surgical Blood Loss
- Trial name
- NCT07352761
- Testing
- Temporary clipping of uterine artery, Temporary occlusive suturing of uterine artery, Bipolar coagulation of uterine arteries
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
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