Clinical trials: Laparoscopic Surgical Procedures
Appendicitis Acute
Low vs Medium Pressure Pneumoperitoneum
The purpose of this study is to asses whether the pressure used for the pneumoperitoneum during laparoscopic surgery in children affects their postoperative pain levels.
- Trial name
- LoMePneu (NCT04949659)
- Testing
- Laparoscopic appendectomy
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- University Children's Hospital, Zurich
Acute Mesenteric Ischemia
ThromBus Aspiration for Acute Mesenteric Artery Occlusion With Emergent Laparoscopic Surgery
This study is designed as a prospective, multicenter, single-arm clinical trial. Patients with acute mesenteric ischemia (AMI) caused by superior mesenteric artery (SMA) thrombosis or thromboembolism will be enrolled.
- Trial name
- BOWEL-2 (NCT07741318)
- Testing
- thrombus aspiration-based endovascular therapy
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
UTERINE CERVICAL NEOPLASMS, ENDOMETRIAL NEOPLASMS
Cost-Effectiveness and Patients Satisfaction of Conventional vs Robotic-Assisted Laparoscopy in Gynecologic Oncologic Indications
Laparoscopic surgery is gaining currency in the field of oncologic care, particularly for colorectal and gynecologic cancers. This innovation could be used either for staging purpose and therefore could steer global therapeutic…
- Trial name
- NCT02865889
- Testing
- Laparoscopy in Gynecologic Oncologic Indications, Conventional surgery (abdominal radical surgery)
- Where
- France
- Volunteers
- 343 people
- Sponsor
- Institut Paoli-Calmettes
Laparoscopic Surgery, Herniorrhaphy
Comparison the Analgesic Efficacy of Ultrasonographic Bilateral TAP and Anesthetic Infiltration Into the Surgery Field for Laparoscopic Unilateral TEP Herniorrhaphy
Laparoscopic inguinal hernia repair is a common surgical procedure, but postoperative pain management remains a challenge. This prospective, randomized study aims to compare the analgesic efficacy of preperitoneal and surgical…
- Conditions
- Laparoscopic Surgery, Herniorrhaphy, Inguinal Hernia Unilateral, Transversus Abdominis Plane (TAP) Block
- Trial name
- NCT06894420
- Testing
- Surgeon-Initiated Local Anesthetic, Transversus abdominis plane (TAP) block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Internal Jugular Vein (IJV) Blood Flow in Gynecological Laparoscopic Surgery
Evaluation of Cerebral Venous Return With Internal Jugular Vein Blood Flow in Gynecological Laparoscopic Surgery
The steep Trendelenburg position (STP) provides an advantage in laparoscopic procedures as it optimizes the surgical image. In laparoscopic operations, the need for CO2 pneumoperitoneum (PP), together with this non-physiological…
- Trial name
- NCT04922060
- Volunteers
- 20 people
- Sponsor
- Selcuk University
Postoperative Ileus
Electroacupuncture for Postoperative Ileus After Laparoscopic Rectal Cancer Surgery
Postoperative ileus remains a significant medical problem after colorectal surgery that adversely influences patients' recovery.
- Trial name
- NCT01844908
- Testing
- Electroacupuncture
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Inguinal Hernia
An Efficiency/Safety Study of Surgical Tissue Glue to Treat Inguinal Hernias
Prospective, multicenter, observational registry to collect data of laparoscopic inguinal hernia repair using surgical tissue glue fixation. The objective is to determine the prevalence of chronic pain at 1 year.
- Trial name
- NCT01669837
- Testing
- Mesh fixation with surgical tissue glue
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- Duomed
Gynecologic Diseases
Ultrasonic Versus Monopolar Energy-based Surgical Device in Colpotomy
The aim of this randomized trial was to compare the degree of surgical smoke obstructing vision and thermal damage caused by two different ESDs (ultrasonic versus monopolar ESD) in colpotomy during total laparoscopic hysterectomy.
- Trial name
- ULMOST (NCT02729272)
- Testing
- Laparoscopic colpotomy by ultrasonic ESD, Laparoscopic colpotomy by monopolar ESD, Monopolar ESD
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Kangbuk Samsung Hospital
Laparoscopic Surgery for Cholecystitis
Clinical Study on the Effect of Tegileridine on Postoperative Pain in Patients Undergoing Abdominal Surgery.
This randomized, double-blind, placebo-controlled study will evaluate the efficacy and safety of tegileridine fumarate injection for postoperative analgesia in adults experiencing moderate-to-severe pain after abdominal surgery.
- Trial name
- NCT07277153
- Testing
- Tegileridine (tegileridine fumarate injection, IV), 0.9% Normal Saline (0.9% Sodium Chloride) injection
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xin Chen
Stomach Neoplasms, Minimally Invasive Surgery
Intracorporeal Versus Extracorporeal Roux-en-Y Esophagojejunostomy During Laparoscopic Total Gastrectomy for Gastric Cancer
To date, Roux-en-Y esophagojejunostomy transabdominal extracorporeally by circular stapler was the most common used method during laparoscopy-assisted total gastrectomy for gastric cancer, even though it was not totally…
- Conditions
- Stomach Neoplasms, Minimally Invasive Surgery, Anastomosis
- Trial name
- NCT02085031
- Testing
- Intracorporeal Roux-en-Y esophagojejunostomy, Extracorporeal Roux-en-Y esophagojejunostomy
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Laparoscopy, Anesthesia Recovery Period
Deep Neuromuscular Block for Laparoscopic Surgery
Trial summary: deep neuromuscular block is proposed as a technique to improve operative conditions for laparoscopy. Early clinical data would suggest that there may also be patient benefits beyond the operative period related to…
- Trial name
- DEEPBLOCK (NCT03034577)
- Testing
- Sugammadex, Neostigmine
- Where
- 4 sites in Australia
- Volunteers
- 350 people
- Sponsor
- University of Melbourne
Pelvic Organ Prolapse, Pelvic Organ Prolapse Vaginal Surgery
To Explore the Surgical Outcomes and Safety of an Innovative Laparoscopic Uterine Pectopexy Technique Using Inverted T-meshes for Simultaneous Apical and Anterior Vaginal Repair.
Patients referred for pelvic reconstructive surgery frequently present with combined anterior and apical vaginal wall prolapse. Previous studies found that anterior compartment involvement is the most common and serious defect…
- Conditions
- Pelvic Organ Prolapse, Pelvic Organ Prolapse Vaginal Surgery, Pectopexy, Sacrocolpopexy
- Trial name
- NCT07411898
- Testing
- Laparoscopic pectopexy, Laparoscopic sacrocolpopexy
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- Chung Shan Medical University
Small Renal Masses
A Trial Comparing - Robotic Assisted Versus Laparoscopic Partial Nephrectomy For Small Renal Masses
A prospective, randomized, controlled trial including patients who are diagnosed with a small renal mass (<4 cm) amenable to resection using either RALPN or LPN.
- Trial name
- RALPLPNNX (NCT02933398)
- Testing
- Robotic Assisted Nephrectomy, Laparoscopic Assisted Nephrectomy
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Colorectal Cancer
Safety and Feasibility of Laparoscopic Intracorporeal Anastomosis for Colorectal Surgery- A Multiple Center Real World Study
The goal of this observational study is to explore the safety and feasibility of laparoscopic intracorporeal anastomosis in colorectal cancer surgery. The main questions it aims to answer are: 1.
- Trial name
- SELECTED (NCT05911152)
- Testing
- Intracorporeal anastomosis
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Pelvic Organ Prolapse, Abdominal Surgery
The Effect of Abdominal Binder Use on Postoperative Pain and Mobility in Patients Undergoing Pelvic Surgery
To determine the effect of post-operative abdominal binder usage on total narcotic usage after undergoing surgery. To determine if abdominal binder usage results in decreased visual analog scale (VAS) pain scores and shorter time…
- Conditions
- Pelvic Organ Prolapse, Abdominal Surgery, Laparoscopic Surgery, Post Operative Pain
- Trial name
- NCT03684304
- Testing
- Abdominal binder
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
The Comparison of the I-gel and Endotracheal Tube About in Different Ventilation Settings During Laparoscopic Surgery
A Study Comparing the Supraglottic Airway Devices and Endotracheal Tube During Controlled Ventilation for Laparoscopic Surgery
In our study, we compared the ventilation performance of i-gel to the endotracheal tube during laparoscopic surgery. The lungs were ventilated at tidal volumes (8mL/kg) using volume controlled.
- Trial name
- NCT02462915
- Testing
- i-gel, endotracheal tube, lidocaine, propofol, fentanyl and cisatracurium
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Postoperative Nausea and Vomiting
Comp Granisetron Midazolam Comb in Lap Children
Postoperative nausea and vomiting (PONV) is one of the most common complications of general anesthesia in pediatrics. Pediatric rates of nausea and vomiting are approximately double those of adult patients.
- Trial name
- NCT03483350
- Testing
- Granisetron, Midazolam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Analgesic Drugs, Analgesic, Nonopioid
Continuous vs. Bolus Administration of NSAIDs After Laparoscopic Surgery for Multimodal Analgesia
Currently the prevalent approach to perioperative management of patients is ERAS (Enhanced Recovery After Surgery) concept. This approach includes numerous aspects, among which the perioperative use of multimodal analgesia takes…
- Conditions
- Analgesic Drugs, Analgesic, Nonopioid, Analgesic Efficacy, Analgetic Consumption
- Trial name
- NCT07070050
- Testing
- Ibuprofen continuous infusion, Ibuprofen bolus injection
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology
Elective Laparoscopic Surgery
Compare Pharmaceutical Economics and Efficacy of Sevoflurane With Low Fresh Gas Flow Balanced Anesthesia, Propofol Target Controlled Infusion Anesthesia and Propofol Induction Sevoflurane Maintenance Anesthesia
This study is being performed to compare the cost of anesthetic techniques with sevoflurane (low fresh gas flow balanced anesthesia) versus propofol (target controlled infusion [TCI]) versus propofol induction and sevoflurane…
- Trial name
- NCT01191476
- Testing
- Sevoflurane Inhalational Induction and Maintenance, Propofol Target Controlled Infusion for Induction and Maintenance, Propofol Target Controlled Infusion for Induction and Sevoflurane Inhalation for Maintenance
- Where
- 4 sites in China
- Volunteers
- 336 people
- Sponsor
- Abbott
Pelvic Organ Prolapse
Laparoscopic Sacrocolpopexy Versus POPS in the Management of Pelvic Prolapse
This is the first study comparing the laparoscopic sacropexy with Pelvic Organs Prolapse Suspension (POPS) to treat pelvic organ prolapse.
- Trial name
- NCT02911584
- Testing
- Laparoscopic procedure
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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