Clinical trials: Laparoscopic Surgical Procedures
Inhalation Anesthesia, Dexmedetomidine
The Impact of a Single Dexmedetomidine Bolus on Intraoperative Sevoflurane Consumption (DEXHALE)
Sevoflurane is a volatile agent easy to control thanks to the Minimum Alveolar Concentration (MAC) allowing its titration for an optimal depth of anesthesia.
- Conditions
- Inhalation Anesthesia, Dexmedetomidine, Sevoflurane, Laparoscopy
- Trial name
- NCT05615194
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Cholecystolithiasis
The Effect of High Frequency Jet Ventilation (HFJV)During Laparoscopic Operations
Investigators conducted a randomised perspective study to determine whether the use of HFJV instead of conventional mechanical ventilation will reduce the adverse cardiovascular effects of pneumoperitoneum during laparoscopic…
- Trial name
- HFJV (NCT01289379)
- Testing
- High Frequency Jet Ventilation, HFJV
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
General Laparoscopic Surgeries
Comparison of Laparoscopic Procedures With and Without the Aid of the AutoLap System- a Robotic Camera Holder
The objective of this study is to evaluate the ability to reduce the number of OR personnel required while performing the following procedures: colon resections, cholecystectomies and anti-reflux/hiatal hernia surgery with the…
- Trial name
- NCT02934542
- Testing
- AutoLap system
- Where
- Netherlands
- Volunteers
- 108 people
- Sponsor
- M.S.T. Medical Surgery Technology LTD.
Overall Survival, Postoperative Complications
Comparative Study of Medial-to-Lateral Approach vs Dorsal and Medial Hybrid Approach in Laparoscopic Right Hemicolectomy
To standardize the surgery for advanced right hemi colon cancer with laparoscopy and investigate whether dorsal and medial hybrid approach could improve disease-free survival in patients with right colon cancer, compared with…
- Trial name
- NCT03364478
- Testing
- DML group, MLA group
- Where
- China
- Volunteers
- 326 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Intracranial Pressure Increase
Do Extraperitoneal Laparoscopic Surgeries Increase Intracranial Pressure?
When the literature is examined, it has been reported in many studies that intracranial pressure increases due to laparoscopic procedures performed in the intraperitoneal area.
- Trial name
- NCT05668208
- Testing
- E-CUBE i7 ultrasound system (Alpinion Medical Systems, Seoul, Republic of Korea)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya City Hospital
Gall Stones
Intraperitoneal Techniques of Local Anaesthesia During Laparoscopic Cholecystectomy
Pain following laparoscopic cholecystectomy (LC) results in morbidity and is a barrier to same day discharge. In several trials local anaesthetic (LA) washed over the liver and gall bladder decreases pain.
- Trial name
- NCT01090882
- Testing
- Bupivocaine, 0.9% normal saline solution
- Where
- United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Gastric Cancer
Effect of Pneumoperitoneum on Remifentanil Requirements in the Surgical Pleth Index-guided Analgesia
The primary purpose of this study is to investigate the effect of pneumoperitoneum on remifentanil requirements in the surgical pleth index-guided analgesia for laparoscopic gastrectomy.
- Trial name
- NCT03788447
- Testing
- High end-tidal CO2, Low CO2 group
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Ajou University School of Medicine
Hysterectomy
Laparoscopic Hysterectomy Via a Single Port, Peri-umbilical Technique Versus a Conventional Laparoscopic Technique
The main objective of the study is the comparison of the effective duration of hospitalization following laparoscopic hysterectomy via a single-port peri-umbilical technique versus an conventional multi-port technique.
- Trial name
- HOT (NCT01830738)
- Testing
- Single-port, peri-umbilical hysterectomy, Multi-port hysterectomy
- Where
- 3 sites in France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Patient Education, Surgical Fear and Worrying
The Effect of Video-Supported Online Preoperative Education on Fear, Anxiety, Sleep, and Stress
Gallbladder stone disease is among the most common digestive system problems worldwide. The global incidence of gallstones is estimated to be 10-20%. In Europe, this rate is approximately 20%.
- Conditions
- Patient Education, Surgical Fear and Worrying, Surgical Stress Response, Medical-surgical Nursing
- Trial name
- NCT07100275
- Testing
- Patient education, Follow-up via Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Bingol University
Uterine Prolapse
Comparison of Laparoscopic to Vaginal Surgical Repair for Uterine Prolapse
Investigators intend to conduct a prospective randomized trial to compare vaginal hysterectomy with uterosacral colposuspension to laparoscopic supracervical hysterectomy with sacrocervicopexy.
- Trial name
- NCT01594372
- Testing
- Laparoscopic supracervical hysterectomy with sacropexy, Vaginal hysterectomy with uterosacral colposuspension
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Brigham and Women's Hospital
Primary Unilateral Inguinal Hernia
SIngle Port vs Standard TEP for Primary Inguinal Hernia Repair
This study is carried out to determine if laparoscopic inguinal TEP repair of the hernia using a mesh carried out with only 1 port (hole) results in the reduction of post- operative pain and use of painkillers, shorter hospital…
- Trial name
- LESSTEP (NCT02302937)
- Testing
- Group A will undergo laparoscopic TEP inguinal hernia repair with 3 ports (10 mm , and 2 ports of 5 mm ), Group B will undergo laparoscopic TEP inguinal hernia repair with a single port
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Ergonomics
Comparative Ergonomic Analysis of Robotic Versus Laparoscopic Surgery
Robotic surgery holds the potential to overcome many of the ergonomic challenges posed by laparoscopic surgery. In this study, we propose to quantify this potential ergonomic benefit by measuring electromyography (EMG) and…
- Trial name
- NCT01903577
- Testing
- Robotic Task Performance, Laparoscopic Task Performance
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Postoperative Pain
The Effectiveness of Acupressure on Reducing Pain and Improving Gastrointestinal Function After Laparoscopic Surgery
The purpose of the study is to explore the effect if acupressure reducing pain after laparoscopic surgery. The study is designed as an experimental research with repeat measurement design.
- Trial name
- NCT05360173
- Testing
- acupressure
- Volunteers
- 86 people
- Sponsor
- China Medical University Hospital
Abdominal Mass
Therapeutic Efficacy of Ramosetron for Treatment of Established PONV After Laparoscopic Surgery
Patients who had at least two risk factors of PONV (Postoperative nausea and vomiting) and underwent laparoscopic surgeries under general anesthesia were assessed for eligibility.
- Trial name
- NCT03017222
- Testing
- Ondansetron, Ramosetron
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Gynecologic Disease, Neuromuscular Blockade
Moderate vs Deep Neuromuscular Block in Lower Pressure Pneumoperitoneum
The investigators hypothesized that deep neuromuscular block compare to moderate neuromuscular block would reduce the rate of increasing intraabdominal pressure and operation can be completely done in lower pressure…
- Trial name
- NCT05689957
- Testing
- Deep neuromuscular block using intravenous rocuronium induction at 1.2mg/kg and maintainance of 8-12mcg/kg/min for deep neuromuscular block
- Where
- Malaysia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Cholecystitis, Acute, Cholecystectomy, Laparoscopic
Implementation of RICA (ERAS) Guidelines in Grade II Acute Cholecystitis Undergoing Early Laparoscopic Cholecystectomy
Background Acute cholecystitis (sudden gallbladder inflammation, usually due to gallstones) is a highly frequent surgical emergency.
- Conditions
- Cholecystitis, Acute, Cholecystectomy, Laparoscopic, Enhanced Recovery After Surgery
- Trial name
- COLERICA II (NCT07695922)
- Testing
- RICA Perioperative Care Pathway
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Hospital d'Igualada
Stress Response
Effect of Dexmedetomidine on Stress Response and Emergence Agitation During Laparoscopic Surgery
Emergence agitation is a post-anesthetic phenomenon that develops in the early phase of general anesthesia recovery, and is characterized by agitation, confusion, disorientation, and possible violent behavior.
- Trial name
- NCT02917018
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Gastric Cancer
National Multicenter Cohort Study of Robot-Assisted Gastrectomy Versus Laparoscopy in Gastric Cancer
In recent years there has been a rapid incursion of robotic technology applied to almost all fields of surgery. In gastric cancer, whose mainstay of treatment is still surgical resection, gastrectomy with robotic lymphadenectomy…
- Trial name
- ROBOTAG (NCT06242613)
- Testing
- Robot-Assisted Gastrectomy, Laparoscopic Gastrectomy
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Morbid Obesity
Comparison of Stapled and Hand-Sewn Sleeve Gastrectomy
Sleeve gastrectomy is a stapler dependent bariatric procedure. A hand-sewn sleeve gastrectomy can be necessary under certain circumstances.
- Trial name
- NCT03982823
- Testing
- Hand-Sewn Sleeve Gastrectomy, Stapled Sleeve Gastrectomy
- Volunteers
- 13 people
- Sponsor
- Inonu University
Obesity, Postoperative Bariatric Surgery
Lung Ultrasound Evaluation of the Effects of PEEP and Recruitment Strategies Adjusted for Intraoperative Dynamic Compliance on Postoperative Respiratory Complications in Obese Patients Planned for Laparoscopic Surgery
This study aims to investigate the effects of the personalized application of respiratory pressures applied to patients undergoing laparoscopic bariatric surgery when they are connected to a ventilator under general anesthesia…
- Conditions
- Obesity, Postoperative Bariatric Surgery, Laparoscopic Surgery, Individualized PEEP Treatment Strategy
- Trial name
- NCT06994780
- Testing
- dynamic compliance guided PEEP titration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
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