Clinical trials: Laparoscopic Surgical Procedures
Shoulder Pain, Nausea
Decreasing Upper and Shoulder Pain After Laparoscopic Surgery
Laparoscopic surgery is becoming a major procedure, owing to smaller incisions, shorter hospitalizations, and less post-operative pain as compared with traditional laparotomies.
- Trial name
- NCT01433874
- Testing
- Pulmonary recruitment maneuver, Intraperitoneal normal saline infusion, combined group
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Pelvic Organ Prolapse (POP), Uterine Prolapse
Effectiveness of Laparoscopic Lateral Suspension With or Without Hysterectomy in Pelvic Organ Prolapse
This study aims to compare the effectiveness of laparoscopic lateral suspension (LLS) with and without hysterectomy in the treatment of pelvic organ prolapse.
- Trial name
- LLS-HYS (NCT07094815)
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Havva Betül Bacak
Colonic Neoplasms
Laparoscopic Surgery for T4 Tumor of the Colon Cancer
The purpose of this study is to compare the short- and long-term survival of laparoscopic surgery and conventional open surgery for T4 colon cancer.
- Trial name
- NCT02852915
- Testing
- Laparoscopic surgery
- Volunteers
- 1,960 people
- Sponsor
- LI XIN-XIANG
Nausea, Vomiting
Periorbital Massage for Nausea and Vomiting After Laparoscopic Surgery
Laparoscopic cholecystectomy is one of the commonly used surgical treatment methods for gallbladder diseases. However, many patients experience significant nausea and vomiting after laparoscopic cholecystectomy.
- Conditions
- Nausea, Vomiting, Laparoscopic Cholecystectomy
- Trial name
- NCT06954935
- Testing
- periorbital massage
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Atlas University
Acute Diverticulitis
The COLD2B Multicenter, Two-arm Prospective Cohort Study
Since it is still debated whether 2b acute diverticulitis (AD), according to the World Society of Emergency Surgery (WSES) classification, should be initially treated surgically or conservatively, the COLD2B study has been…
- Trial name
- COLD2B (NCT06388538)
- Testing
- Conservative treatment (non-operative treatment), Surgical treatment (operative treatment)
- Where
- 4 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Azienda Sanitaria di Firenze
Music Therapy, Cholecystitis/Cholelithiasis
Effect of Preoperative Music on Sterile Inflammation Induced by Laparoscopic Surgery
Surgery induced sterile inflammation leaves behind a biomolecular footprint measurable by various pro-inflammatory markers e.g. IL-6, CD(Cluster of differentiation)19B, HsCRP(High-sensitivity CRP) etc.
- Conditions
- Music Therapy, Cholecystitis/Cholelithiasis, Inflammatory Response, Surgical Injury
- Trial name
- NCT03429478
- Testing
- Preoperative application of a bluetooth enabled Headphones.
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Sir Ganga Ram Hospital
Endometriosis Ovary
Deep Infiltrating Endometriosis : Laparoscopic Nerve-sparing Surgery and Use of Neutral Argon Plasma
Medical treatment of endometriosis has a suspensive and sometimes incomplete effect on the symptoms, making surgical treatment necessary.
- Trial name
- DIE (NCT06207448)
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Strasbourg, France
Postoperative Nausea and Vomiting
Comp Granisetron Midazolam Comb in Lap Children
Postoperative nausea and vomiting (PONV) is one of the most common complications of general anesthesia in pediatrics. Pediatric rates of nausea and vomiting are approximately double those of adult patients.
- Trial name
- NCT03483350
- Testing
- Granisetron, Midazolam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Laparoscopic Surgery
The Use of Tidal Volume Challenge of Dynamic Parameters During Laparoscopic Surgery
Laparoscopy is increasingly used for major abdominal and pelvic surgery. As this approach is also recommended in elderly patients with serious comorbidities, optimal fluid therapy guidance during this procedure is important.
- Trial name
- NCT03467711
- Testing
- tidal volume challenge, volume expansion
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Shoulder Pain, Hiatal Hernia
Pain Relief After Hiatal Hernia Repair Surgery
Referred shoulder pain (pain felt when the problem is actually in a different location) is very common after laparoscopic (small, narrow cut) hernia surgery.
- Trial name
- NCT04936711
- Testing
- Resteck Shiatsu Neck and Back Massager, Marcaine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Norton Thoracic Institute
Hepatocellular Carcinoma
Laparoscopic Versus Open Major Hepatectomy for HCC Hepatectomy for Hepatocellular Carcinoma
Background: Hepatocellular carcinoma (HCC) is the sixth most common malignancy in the world. Major hepatectomy (resection of > 3 liver segments) is needed if tumor is close to major blood vessels within liver.
- Trial name
- AP-LAPO (NCT04852211)
- Testing
- Open or laparoscopic surgery
- Where
- Hong Kong
- Volunteers
- 212 people
- Sponsor
- Chinese University of Hong Kong
Postoperative Nausea and Vomiting
Transdermal Nicotine in Female Patients at High Risk for Post Operative Nausea and/or Vomiting (PONV)
The purpose of this study is to see if the nicotine patch reduces post operative nausea and/or vomiting (PONV) among non-smoking patients who are at high risk of PONV.
- Trial name
- NCT00775749
- Testing
- transdermal nicotine patch
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
Ovarian Torsion
Ovarian Reserve After Ovarian Torsion
Ovarian torsion is a relatively common gynecological emergency, usually presenting as acute lower abdominal pain. Due to patient's presentation diversity, the diagnosis is clinical and requires integration of different factors…
- Trial name
- OTAMH (NCT03852615)
- Testing
- Pre operation Blood sample for AMH, 3 month post operation blood sample for AMH
- Where
- Israel
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Ergonomics
These Studies Assess Surgeons' Physical and Ergonomic Workloads. Study 1 Compares Laparoscopic vs. Hugo RAS Robotic Approaches for Rectal Resection. Study 2 Compares Hugo RAS vs. Da Vinci Xi for Prostatectomy. Both Track Physiological Stress, Surgical Strain Phases, and Exerted Force.
The ERGOROB (ERGOnomics in surgical ROBotics) study is an observational research project focused on the physical well-being of surgeons.Why is this study important?Surgeons perform complex, lengthy procedures that can lead to…
- Trial name
- ERGOROB (NCT07479121)
- Testing
- surgical approach
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pain, Postoperative, Anesthesia
Comparison of Remifentanil-induced Postoperative Hyperalgesia Between Patients From Plain Area and Plateau Area
Purpose: 1. To compare the incidence of postoperative hyperalgesia induced by remifentanil in patients undergoing gynecological laparoscopic surgery in plateau and plain areas 2.
- Trial name
- NCT05028049
- Testing
- Sufentanil injection, Remifentanil Hydrochloride, plain areas
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Tianjin Medical University General Hospital
Postoperative Cognitive Dysfunction
Optic Nerve Sheath Diameter and Postoperative Cognitive Disfunction at Laparoscopic Surgery
Purpose: Pneumoperitoneum during laparoscopic abdominal surgery increases intra-abdominal pressure (IAP), potentially altering intracranial pressure (ICP) and cerebral oxygenation, with unclear implications for early…
- Trial name
- NCT07264764
- Testing
- Optic nerve sheath diameter (ONSD)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Duzce University
Prolapse Genital, Prolapse Uterovaginal
Posterior Mesh Fixation at the Levator Ani Level in Apical Pelvic Organ Prolapse
This is a prospective, randomized, multicenter, non-inferiority trial including women with stage II-IV apical pelvic organ prolapse (POP), classified according to the POP-Q system.
- Conditions
- Prolapse Genital, Prolapse Uterovaginal, Prolapse; Female
- Trial name
- FIMEA (NCT07194343)
- Testing
- Laparoscopic colposacropexy with levator ani muscle mesh fixation, Simplified modification of laparoscopic colposacropexy
- Where
- 6 sites in Spain
- Volunteers
- 190 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Colorectal Cancer, Colonic Neoplasms
Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer
This study is designed to evaluate the short-term and long-term results after single incision laparoscopic surgery for colorectal cancer（SILSC） compared with conventional laparoscopic surgery for colorectal cancer（CLSC）.
- Conditions
- Colorectal Cancer, Colonic Neoplasms, Rectal Neoplasms, Colon Disease
- Trial name
- mSILSC (NCT03633539)
- Testing
- Single-incision Laparoscopic Surgery, Conventional Laparoscopic Surgery
- Where
- China
- Sponsor
- Ruijin Hospital
Gastrectomy for Gastric Cancer, Robotic Surgical Procedures
Assessment of Robotic Versus Laparoscopic Gastrectomy for GC Patients With Intraoperative Technical Complexity
While robotic gastrectomy (RG) is increasingly used in gastric cancer surgery, its potential advantages over laparoscopic gastrectomy (LG) in Intraoperative technical complexity (ITC) cases remain debated.
- Conditions
- Gastrectomy for Gastric Cancer, Robotic Surgical Procedures, Laparoscopic Surgical Procedures
- Trial name
- NCT06752538
- Where
- China
- Volunteers
- 3,534 people
- Sponsor
- Fujian Medical University
Scheduled Laparoscopic Surgery
Pupillary Reflex Measurement to Guide Intraoperative Analgesia During Laparoscopic Surgery
The purpose of this study is to determine whether analgesia guided by pupillary reflex during laparoscopic surgery is effective in opioid sparing (intraoperative remifentanil and postoperative morphine).This is a prospective…
- Trial name
- NCT02116868
- Testing
- Pupillometry guided analgesia (PP), Tailored remifentanil controlled infusion, Tailored antihypertensive drug administration
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
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