Clinical trials: Laparotomy Surgery
Postoperative Pain
Epidural Catheter and Surgically Implanted Rectus Sheath Catheter in Management of Postoperative Pain
One hundred and twenty patients at age range from 18 to 60 undergoing laparotomy was enrolled in this study. Patients were randomly assigned to two groups 60 in epidural group and the other 60 patients in rectus catheter group.
- Trial name
- NCT04755725
- Testing
- Epidural catheter, rectus sheath catheter
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Menoufia University
Genital Neoplasm Malignant Female, Surgical Procedure, Unspecified
A Trial Comparing Surgeon-administered TAP Block With Placebo After Midline Laparotomy in Gynecologic Oncology
Multimodal opioid-sparing analgesia is recommended in order to prevent post-operative complications and shorten length of stay. Administration by the surgeon of local anesthetics in the abdominal wall after surgery for a…
- Trial name
- NCT04202874
- Testing
- Surgeon-administered transversus abdominis plane (TAP)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- McMaster University
Perforated Viscus, Intestinal Obstruction
Acute High-risk Abdominal Surgery Study - an Optimized Perioperative Course
The objective of this study is to implement an optimized perioperative course for patients undergoing acute high-risk abdominal surgery in order to improve the outcome.
- Trial name
- AHA (NCT01899885)
- Testing
- AHA (Acute Highrisk Abdominalsurgery): Optimized Course
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Hvidovre University Hospital
Emergency Abdominal Surgery, Opioid Sparing Anaesthesia
Effect of Opioid-sparing Anesthesia on Quality of Recovery After Emergency Laparotomy
Opioids are widely used during anesthesia for pain control, but they cause many side effects-such as nausea, constipation, respiratory depression, dependence, and delayed recovery.
- Trial name
- NCT07262242
- Testing
- Lidocaine (drug), Fentanyl (IV)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Upper Gastrointestinal Cancer
The Efficacy and Safety of Accufuser Omnibus® (Elastomeric Infusion Pump); Comparative Clinical Trial
Acute post-operative pain causes not only discomfort for the patient, but delays recovery by increasing the morbidity of the circulatory system, respiratory system, and immune system, so pain control is one of the important…
- Trial name
- NCT01976494
- Testing
- The domestic PCA equipment 'Accufuser Omnibus®', Imported PCA equipment 'Infusor SV®, Baxter, USA'
- Where
- South Korea
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Emergency General Surgery Laparotomy
Surgical Apgar Score for Identifying Patients Who May Need Intensive Care After Emergency Abdominal Surgery
This prospective observational study will evaluate whether the Surgical Apgar Score can help identify patients who require direct admission to the intensive care unit after emergency abdominal surgery.
- Trial name
- SAS-ICU (NCT07814131)
- Where
- Pakistan
- Volunteers
- 77 people
- Sponsor
- King Edward Medical University
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Colorectal Cancer, Metastatic Cancer
SCH 66336 Before Surgery in Treating Patients With Colorectal Cancer That Has Metastasized to the Liver
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Randomized phase I trial to compare the effectiveness of different doses of SCH 66336 before surgery…
- Trial name
- NCT00005030
- Testing
- SCH 66336, conventional surgery
- Sponsor
- M.D. Anderson Cancer Center
Laparotomy
Supplemental Oxygen - Effect on Occurrence of Subsequent Cancer After Abdominal Surgery (Follow-up of the PROXI Trial)
Aim: to investigate the effect of a high inspiratory oxygen fraction (FiO2) given during and after laparotomy procedures on occurrence of a subsequent, new or recurrent, cancer diagnosis at a long-term follow-up.
- Trial name
- PROXI (NCT01723280)
- Testing
- Oxygen
- Where
- Denmark
- Volunteers
- 1,386 people
- Sponsor
- Lars S. Rasmussen
Wound Infection
Antiseptic Sutures and Wound Infection
The aim of this study was to ascertain if the use of Vicryl plus® reduced the number of wound infections after transverse laparotomy comparing to polydioxanon suture.
- Trial name
- NCT00932503
- Testing
- Vicryl plus
- Where
- Germany
- Volunteers
- 839 people
- Sponsor
- University Hospital, Saarland
Rectal Cancer
Rectal Surgery Evaluation Trial (RESET)
Total mesorectal excision (TME) is the standard of care for rectal cancer, which can be combined with low anterior resection (LAR) in patients with mid-to-low rectal cancer.
- Trial name
- RESET (NCT03574493)
- Testing
- TME with LAR
- Where
- France
- Volunteers
- 1,098 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Surgery
Crystalloids or Colloids for Goal-directed Fluid Therapy With Closed-loop Assistance in Major Surgery
Study goal: This study will examine whether there is a significant difference in postoperative outcomes between GDFT using a colloid solution versus a crystalloid solution.
- Trial name
- NCT02312999
- Testing
- Plasmalyte, Volulyte
- Where
- 2 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- Brugmann University Hospital
Abdominal Aortic Aneurysm, Morbid Obesity
Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
The aim of the study is to describe the effectiveness of Optilene® Silver Mesh Elastic on prevention of surgical site infection (SSI) at 6 months follow-up in patients undergoing urgent laparotomy by collecting clinical data on…
- Trial name
- SSIHLVER (NCT06547138)
- Testing
- Prophylactic mesh
- Where
- 5 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Aesculap AG