Clinical trials: Large for Gestational Age
Birth Weight, Small for Gestational Age at Delivery
Drinking Water PFAS, Pregnancy Outcome and Maternal Morbidity
The aim of the project is to assess the association between exposure to per- and polyfluoroalkyl substances (PFAS) via drinking water in pregnancy and birth outcomes (i.e.
- Conditions
- Birth Weight, Small for Gestational Age at Delivery, Large for Gestational Age at Delivery (Macrosomia), Diabetes, Gestational
- Trial name
- NCT05810545
- Testing
- Per- and polyfluoroalkyl substances (PFAS)
- Volunteers
- 256,659 people
- Sponsor
- Karolinska Institutet
Diabetes Mellitus, Pregnancy
Improving Outcomes in Underserved Women With GDM
Our objective is to test an innovative approach to improve outcomes among underserved women with gestational diabetes. We ill utilize a multi-lingual, Interactive Voice Response (IVR) -enabled telephone system to facilitate…
- Trial name
- NCT00774124
- Testing
- telemonitoring, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 57 people
- Sponsor
- Temple University
Obesity; Endocrine, Pregnancy in Diabetic
Female Obesity Cohort and Intervention Study Group (MOCART Study Group)
This prospective observational trial includes women with high risk pregnancies complicated with hyperglycemia in pregnancy and excessive body weight.
- Conditions
- Obesity; Endocrine, Pregnancy in Diabetic, Child Obesity, Hypertension in Pregnancy
- Trial name
- MOCART (NCT04924738)
- Testing
- Monitoring and lifestyle
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Poznan University of Medical Sciences
Pregnancy Complications
Measuring sVAP-1 as a Predictor of Pregnancy Problems
Pre-eclampsia is a common pregnancy disorder defined as high blood pressure and protein in the urine after 20 weeks of pregnancy.
- Trial name
- NCT04891315
- Testing
- Blood test for soluble VAP-1 (sVAP-1).
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Gestational Diabetes, Pregnancy
Comparison of Two Screening Strategies for Gestational Diabetes (GDM2)
This is a single site blinded RCT of 920 pregnant women with singleton gestation designed to compare the Carpenter-Coustan and IADPSG criteria for diagnosing gestational diabetes.
- Conditions
- Gestational Diabetes, Pregnancy, Glucose Intolerance
- Trial name
- GDM2 (NCT02309138)
- Testing
- Gestational diabetes screening with fasting 3 hour 100 gm, Gestational diabetes screening with fasting 2 hour 75g
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- Esa M Davis, MD MPH FAAFP
Obesity, Gestational Diabetes
Impact of Diet and Exercise Activity on Pregnancy Outcomes
The general goal of the present study is to assess the impact of a community-based exercise and dietary intervention in pregnant women living in urban areas during and after their pregnancy on the reduction of the risks of both…
- Conditions
- Obesity, Gestational Diabetes, Type 2 Diabetes
- Trial name
- IDEA (NCT00486629)
- Testing
- Exercise and dietary education
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Postpartum Urinary Incontinence, Postpartum Depression (PPD)
Prenatal Exercise Including Perineal Massage and Maternal-Neonatal Outcomes
The study is divided into three phases: Phase 1: Baseline survey to obtain an overall understanding of the current situation of voluntary participation in prenatal perineal massage.
- Conditions
- Postpartum Urinary Incontinence, Postpartum Depression (PPD), Neonatal Complications, Gestational Diabetes
- Trial name
- PEPM-RCT (NCT07314502)
- Testing
- Supervised prenatal exercise including antenatal perineal massage
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- South China Normal University
Diabetes, Pregnancy
The Effect of Real-time Continuous Glucose Monitoring on Severe Complications to Pregnancy in Women With Diabetes
The purpose of the study is to investigate the effects of Real-time Continuous Glucose Monitoring on severe complications to pregnancy in women with diabetes.
- Trial name
- NCT00994357
- Testing
- Real-time CGM, Standard care
- Volunteers
- 154 people
- Sponsor
- University of Copenhagen
Gestational Diabetes, Diabetes
The DNA Methylation of ARHGEF11 in Macrosomia
Background Macrosomia at birth is associated with subsequent susceptibility to obesity, abnormal glucose metabolism, hypertension and dyslipidaemia.
- Conditions
- Gestational Diabetes, Diabetes, Macrosomia, Fetal
- Trial name
- NCT03165643
- Testing
- OGTT
- Volunteers
- 239 people
- Sponsor
- Peking University First Hospital
Weight Gain
Weight Gain During Pregnancy - a Randomized Controlled Trial of Intervention to Prevent Excessive Gestational Weight Gain
Excessive weight gain during pregnancy is associated with complications during delivery primarily due to macrosomia (large babies) but also with high levels of weight retention post pregnancy and thereby increased risk of future…
- Trial name
- VIGA (NCT00451425)
- Testing
- motivational intervention in pregnancy
- Where
- Sweden
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Macrosomia, Low Birth Weight
Wales Electronic Cohort for Children
The investigators are developing a research platform capable of improving children's health through the generation of knowledge from analysis of routinely collected data from within and outside the health service.
- Conditions
- Macrosomia, Low Birth Weight, Premature Birth, Childhood Obesity
- Trial name
- WECC (NCT01136681)
- Where
- 2 sites in United Kingdom
- Volunteers
- 900,000 people, healthy volunteers welcome
- Sponsor
- Swansea University
Fetal Macrosomia, Obesity Complicating Childbirth
Investigating the Relationship Between Triglycerides and Fetal Overgrowth in Gestational Diabetes
This is a prospective, observational study which examines the association between maternal triglycerides in the antepartum period and fetal overgrowth in pregnancies complicated by gestational diabetes.
- Conditions
- Fetal Macrosomia, Obesity Complicating Childbirth, Gestational Diabetes
- Trial name
- NCT06067685
- Testing
- Observation
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Fetal Macrosomia, Abdominal Wall Mass
Fetal Front-abdominal Wall Thickness and Perinatal Outcome
Abnormal fetal development such as macrosomia can cause some complications on both fetus and mother.The measurement of fetal anterior abdominal wall thickness (FAWT) is an easy examination that it can be obtained during an…
- Conditions
- Fetal Macrosomia, Abdominal Wall Mass, Perinatal Problems
- Trial name
- NCT03232294
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Gestational Diabetes
The Role of Umbilical Cord Thickness in Prediction of Fetal Macrosomia in Patients With Gestational Diabetes Mellitus
The aim of this work is the prediction of fetal macrosomia by measuring: 1. HbA1C. 2. Umbilical cord thickness. 3. Interventricular septum thickness.
- Trial name
- NCT02643225
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Childhood Overweight
Effects of Lifestyle Intervention on Childhood Outcomes in LGA Infants
Large-for-gestational-age (LGA) infants have a higher risk of metabolic disease later in life, and their postnatal growth in early childhood may be associated with long-term adverse outcomes.
- Trial name
- NCT04661449
- Testing
- Comprehensive lifestyle intervention
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Pregnancy Complications, Obesity
Metformin in Obese Non-diabetic Pregnant Women
Obesity is on the rise in all developed countries. Of particular concern is that more young people including children are being recognised as being overweight or obese.
- Trial name
- MOP (NCT01273584)
- Testing
- Metformin
- Where
- 3 sites in United Kingdom
- Volunteers
- 450 people
- Sponsor
- Epsom and St Helier University Hospitals NHS Trust
Macrosomia, Fetal
Improving Patient Understanding of Macrosomia
The purpose of this study is to evaluate the effectiveness of a graphic based education tool on patient knowledge of macrosomia through the use of a survey and to evaluate knowledge at 1-2 weeks after initial review of the…
- Trial name
- NCT06281301
- Testing
- education tool, no additional information
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hypoglycemia, Infant, Small for Gestational Age
Dextrose Gel Does Not Prevent Neonatal Hypoglycemia
This was a quasi-experimental pilot study comparing blood glucose values 30 minutes after feeding alone or feeding + dextrose gel in newborns at risk for transient neonatal hypoglycemia.
- Conditions
- Hypoglycemia, Infant, Small for Gestational Age, Premature Birth of Newborn, Fetal Macrosomia
- Trial name
- NCT02523222
- Testing
- 40% Dextrose gel
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Baylor College of Medicine
Overweight and Obesity, Weight Loss
PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus
The study is a single site parallel randomized controlled study. The study will be assessing the effect of a 10% pre-conceptional weight loss intervention vs a control group among healthy couples where the prospective mother is…
- Conditions
- Overweight and Obesity, Weight Loss, Pregnancy Related, Child Nutrition Sciences
- Trial name
- PREPARE CHILD (NCT05798494)
- Testing
- Weight loss intervention
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ulla Kampmann Opstrup
Gestational Diabetes Mellitus
Randomized Translational Study to Examine the Effects of Shared Care in Management of Gestational Diabetes
Research question (s)/hypothesis: 1. . The effectiveness of the shared care management of gestational diabetes mellitus; 2. . The cost-effectiveness of the shared care management; 3. . Its sustainability
- Trial name
- NCT01565564
- Testing
- Shared glycaemic control care within the local three-tier's antenatal care network
- Where
- China
- Volunteers
- 948 people
- Sponsor
- Tianjin Women and Children's Health Center