Clinical trials: Laryngeal Obstruction
Muscle Tension Dysphonia, Vocal Fold Palsy
Evaluating the Feasibility of Acapella® Choice as a Dysphonia Treatment
A feasibility study to identify the immediate effect on the voices of patients with voice disorders (muscle tension dysphonia, vocal fold palsy or presbylaryngis) produced by exercising with Acapella Choice as a form of…
- Conditions
- Muscle Tension Dysphonia, Vocal Fold Palsy, Vocal Cord Paralysis, Presbylarynx
- Trial name
- NCT04764604
- Testing
- Acapella Choice, Tube-in-water
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College, London
Exercise Induced Laryngeal Obstruction (EILO)
Atrovent in Exercise Induced Laryngeal Obstruction (EILO)
Exercise Induced Laryngeal Obstruction (EILO) is a condition not uncommon in otherwise healthy young people. EILO is caused by posteromedial collapse of supraglottic structures or medialization of the vocal folds, or both, during…
- Trial name
- NCT02755714
- Testing
- Ipratropium bromide spray
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Haukeland University Hospital
Vocal Cord Disease, Vocal Cord Polyp
Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery
Patients undergoing surgery on their vocal cord will either receive a numbing injection to their throat or a saline injection during surgery.
- Conditions
- Vocal Cord Disease, Vocal Cord Polyp, Vocal Cord Cyst
- Trial name
- NCT06734975
- Testing
- Superior laryngeal nerve block - Intervention (Bupivacaine and triamcinolone acetonide suspension)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Rutgers, The State University of New Jersey
Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative
Peri-operative BiPAP to Prevent Tracheostomy in High-Risk Bilateral Vocal-Cord Paralysis (BVCP)
Why: After thyroid or neck surgery, some patients can lose movement of both vocal cords (bilateral vocal-cord paralysis, BVCP). This can make breathing difficult and often leads to an emergency or preventive tracheostomy…
- Conditions
- Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative, Thyroid Neoplasms, Sleep Apnea, Obstructive
- Trial name
- BVCP-BiPAP (NCT07042971)
- Testing
- Pre-operative BiPAP Training, Post-extubation BiPAP Support, Standard Peri-operative Care
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Fujian Medical University
Laryngeal Neoplasm
The Efficacy of Superficial Cervical Block Application in Postoperative Analgesia Management in Patients Undergoing Total Laryngectomy and Bilateral Neck Dissection
The goal of this clinical trial is to evaluate the efficacy of the superficial cervical block in postoperative pain management for patients undergoing total laryngectomy and bilateral neck dissection.
- Trial name
- NCT06852651
- Testing
- Superficial Cervical Block (SCB) Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Cough, Superior Laryngeal Nerve Block
Efficacy of SLN Block for Chronic Cough
This is a research study to find out if superior laryngeal nerve blocks are an effective way to reduce cough when compared to placebo (a substance without any medical value).
- Conditions
- Cough, Superior Laryngeal Nerve Block, Neurogenic Cough
- Trial name
- NCT04421092
- Testing
- Superior laryngeal nerve block, Injection of steroid-lidocaine mixture
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Anesthesia, Local, Voice Change
Voice Quality Changes With IANB Anesthesia
Background: Inferior alveolar nerve block anesthesia is commonly used in dental procedures, but its effect on the voice quality is not well understood.
- Trial name
- NCT05710484
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Marmara University
Laryngeal Nerve Block, Chronic Neurogenic Cough
Laryngeal Nerve Block for Chronic Cough
The purpose of this study is to study the potential benefit of treating chronic neurogenic cough by blocking the nerve responsible for the disease with an injection of local anesthetic/steroid mixture versus a placebo.
- Conditions
- Laryngeal Nerve Block, Chronic Neurogenic Cough, Laryngeal Hypersensitivity
- Trial name
- NCT05292677
- Testing
- Steroid/Anesthesia Mixture
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Eastern Virginia Medical School
Airway Obstruction, Difficult Intubation
Evaluation of the Use of Tracheal Intubation Through a Laryngeal Tube to Intubate Anesthetized Patients
Failed intubation is currently one of the most important factors leading to morbidity and mortality in anesthesia. The development of supraglottic airway devices (SGDs), such as the intubating laryngeal tube, has revolutionized…
- Trial name
- IKING (NCT03165461)
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Formacion Internacional para la Docencia e Investigación de la Vía Aérea
Exercise Induced Laryngeal Obstruction, Asthma in Children
Prevalence of EILO Among Children With Asthma
The goal of this cross-sectional study is to investigate the prevalence of Exercise Induced Laryngeal Obstruction (EILO) in children with asthma.
- Conditions
- Exercise Induced Laryngeal Obstruction, Asthma in Children, Exercise-Induced Bronchospasm, Exercise-Induced Bronchoconstriction
- Trial name
- NCT06480084
- Testing
- Continuous Laryngoscopy during Exercise Test (CLE test)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Medisch Spectrum Twente
Superior Laryngeal Nerve Block
Ultrasound-guided Thyroid Cartilage Plane Block for Awake Intubation
The goal of this clinical trial is to investigate the clinical effectiveness and safety of superior laryngeal nerve block through surface injection of local anesthetic solution on the thyroid cartilage in patients undergoing…
- Trial name
- NCT06065475
- Testing
- Ultrasound-guided bilateral Thyroid Cartilage Plane Block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Postoperative Sore Throat
Ultrasound-Guided Internal Superior Laryngeal Nerve Block for Double-Lumen Bronchial Tube
investigate the effectiveness and safety of ultrasound-guided bilateral internal branch of the SLN (iSLN) block for alleviating POST immediately after the operation.
- Trial name
- NCT05825872
- Testing
- internal superior laryngeal nerve block, Lidocaine 2% Injectable Solution, Bupivacaine 0.5% Injectable Solution
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Menoufia University
Awake Endotracheal Intubation, Difficult Intubation
Superior Laryngeal Nerve Block For Awake Endotracheal Intubation Study
Awake tracheal intubation is the standard management for patients as risk for airway compromise. It is also commonly done in cases where there is significant cervical spine pathology i.e. cervical myelopathy or instability.
- Conditions
- Awake Endotracheal Intubation, Difficult Intubation, Airway Anesthesia
- Trial name
- NCT01848548
- Testing
- Superior Laryngeal Nerve Block using the Thyrohyoid Membrane as an Anatomic Landmark
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wake Forest University Health Sciences
Thyroid Surgery
Effect of Cervical Block on Recurrent Laryngeal Nerve Monitoring During Thyroid Surgery
Non-inferiority study aimed to assess the impact of cervical block on recurrent laryngeal nerve monitoring during thyroid surgery Secondary outcomes will assess post-operative recovery, post-operative pain and post-operative…
- Trial name
- THYRODOUL2 (NCT04585126)
- Testing
- Intermediate cervical block
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Vocal Cord Dysfunction, Asthma Brittle
Is Laryngeal Ultrasound Useful in the Assessment for ILO? A Protocol for a Two-stage Exploratory Pilot Study
This study is a feasibility study to see if an ultrasound scan of the vocal cords can detect narrowing of the vocal cords as seen in a condition called inducible laryngeal Obstruction (the vocal cords narrow or close on breathing…
- Conditions
- Vocal Cord Dysfunction, Asthma Brittle, Inducible Laryngeal Obstruction, Paradoxical Vocal Fold Motion
- Trial name
- NCT05686941
- Testing
- Trans-cutaneous Laryngeal ultrasound (TLUS), TLUS and simultaneous laryngoscopy
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Exercise-Induced Laryngeal Obstruction
Headgear Accessory for Exercise-Induced Laryngeal Obstruction Studies
Exercise-induced laryngeal obstruction (EILO) is a condition in which the larynx, or voice box, narrows during high-intensity exercise, and is often mis-diagnosed.
- Trial name
- HALOS (NCT05314478)
- Testing
- Continuous laryngoscopy during exercise test using the HALOS headgear
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Exercise Induced Laryngeal Obstruction (EILO)
HelpILO - RCT on EILO Treatment
Exercise induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young individuals, caused by paradoxical inspiratory adduction of laryngeal structures, and diagnosed by continuous visualization…
- Trial name
- NCT04620343
- Testing
- A: Breathing advice with bio-feedback, B: Breathing advice with bio-feedback, Inspiratory muscle training (IMT), C: Breathing advice with bio-feedback, Speech Therapy
- Where
- Norway
- Volunteers
- 350 people
- Sponsor
- Haukeland University Hospital
General Anesthesia, Breast Disease
Neuromuscular Block in Laryngeal Mask Airway(LMA) Insertion
The aim of this study is to evaluate the success rate, insertion time and complication depending on the use of neuromuscular blocking agent when inserting the laryngeal mask airway (LMA).
- Trial name
- NCT01035021
- Testing
- use of rocuronium when the LMA is inserted
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Seoul National University Bundang Hospital
Airway Obstruction
Comparison of High Dose and Low Dose Dexamethasone in Preventing Post-Extubation Airway Obstruction in Adults
The specific objectives were to determine whether high dose dexamethasone are more effective than low dose dexamethasone in the reduction or prevention of post-extubation airway obstruction among patients with a cuff leak volume…
- Trial name
- NCT00548483
- Testing
- dexamethasone (Oradexon, Nederland)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Mackay Memorial Hospital
Bilateral Vocal Cord Paralysis
Selective Laryngeal Reinnervation for Bilateral Vocal Fold Paralysis
This is a prospective observational study examining the treatment outcomes of selective laryngeal reinnervation procedures for patients with bilateral vocal fold paralysis.
- Trial name
- NCT03980275
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Weill Medical College of Cornell University