Clinical trials: Laser, open to volunteers
Lumbar Microdiscectomy, Postoperative Rehabilitation
Effectiveness of a Visual Feedback Exercise Program Following Lumbar Surgery
The aim of this study is to compare the effectiveness of stabilization exercises performed with visual feedback guided by a laser pointer after lumbar microdiscectomy surgery with that of standard stabilization exercises.
- Conditions
- Lumbar Microdiscectomy, Postoperative Rehabilitation, Randomized Controlled Trial
- Trial name
- NCT07382830
- Testing
- Exercise, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Suleyman Demirel University
Primary Open Angle Glaucoma, Ocular Hypertension
DSLT for Reducing Medication in Glaucoma
This is a prospective, single arm, open label study conducted at a single site to evaluate the efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in reducing medication burden in patients with medically controlled ocular…
- Trial name
- NCT07390890
- Testing
- Voyager DSLT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Eye Institute of West Florida
Chronic Low Back Pain
Efficacy of Low-Dose Laser Acupuncture for Low Back Pain
This study will evaluate whether low-dose laser acupuncture can reduce pain and improve daily function in adults with chronic low back pain. The trial is a double-blinded, randomized, two-arm, parallel, multi-centred study.
- Trial name
- NCT07461363
- Testing
- Low-Dose Laser Acupuncture
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Mun Fei Yam
Venous Leg Ulcer (VLU), Venous Hypertension Ulcers
Effect of Photobiomodulation on Healing of Venous Leg Ulcers
Venous leg ulcers are a significant public health problem because of their prolonged duration, high recurrence rates, and economic, social, and quality-of-life effects.
- Conditions
- Venous Leg Ulcer (VLU), Venous Hypertension Ulcers, Chronic Venous Insufficiency, Chronic Venous Disease
- Trial name
- NCT07123285
- Testing
- Photobiomodulation Therapy, Compression Therapy
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- University of Nove de Julho
Pancreatic Cancer Patients Diagnosed With Locally Advanced or Metastatic Pancreatic Cancer Not Amenable to Curative Surgical Resection, Pancreatic Cancer Borderline
EGFR Targeted Photoimmunotherapy With ASP-1929 for Locally Advanced Pancreatic Cancer
This is an open label phase II study to determine the safety and preliminary efficacy of photoimmunotherapy (PIT) for patients with locally advanced and borderline resectable pancreatic cancer.
- Conditions
- Pancreatic Cancer Patients Diagnosed With Locally Advanced or Metastatic Pancreatic Cancer Not Amenable to Curative Surgical Resection, Pancreatic Cancer Borderline, Pancreatic Cancer Resectable
- Trial name
- NCT07698613
- Testing
- ASP-1929 photoimmunotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brown University
Periodontitis, Periodontal Debridement
A Non-inferiority Study of Laser Combined With Ultrasonic Debridement Therapy (LCUDT) Versus Manual Combined With Ultrasonic Debridement Therapy (MCUDT) in the Treatment of Periodontitis
The rate of periodontal health among adults and the elderly in China is less than 10%, with the prevalence of severe periodontitis reaching 30.6% in those aged 35 and above.
- Trial name
- NCT07487285
- Testing
- Experimental: Laser Combined with Ultrasonic Debridement Therapy, Active Comparator: Manual Combined with Ultrasonic Debridement Therapy
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Fetal Conditions, Maternal; Procedure
A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures
In this research study, the investigators want to learn more about the role of new innovative surgical devices, the Karl Storz Curved and Straight Fetoscopes for in-utero surgery.
- Conditions
- Fetal Conditions, Maternal; Procedure, Pregnancy Related, Twin to Twin Transfusion Syndrome
- Trial name
- NCT06056635
- Testing
- Karl Storz Curved Scope, Karl Storz Straight Scope
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Cutaneous Leishminiasis
Comparison of Intralesional Glucantime With and Without Fractional CO₂ Laser in Adults With Cutaneous Leishmaniasis
Cutaneous leishmaniasis is a common parasitic skin disease causing chronic ulcerative lesions and scarring. Intralesional meglumine antimoniate (Glucantime) is a widely used treatment; however, healing may be prolonged and…
- Trial name
- NCT07652021
- Testing
- Meglumine Antimoniate, Fractional CO₂ laser
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Combined military hospital Peshawar
Post-surgical Scars, Hypertrophic Scars
Surgical Care And Recovery With Laser Evaluation Trial (SCARLET)
The Surgical Care and Recovery with Laser Evaluation Trial (S.C.A.R.L.E.T.) is a prospective, single-center clinical study conducted at AdventHealth Medical Group Plastic and Reconstructive Surgery at Innovation Tower.
- Conditions
- Post-surgical Scars, Hypertrophic Scars, Scar Appearance Dissatisfaction, Aesthetic Surgical Outcomes
- Trial name
- SCARLET (NCT07359352)
- Testing
- ProFractional Laser Therapy and/or Broadband Light (BBL) Treatment
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Vitiligo
Topical Methotrexate with Fractional CO2 Laser in Treatment of Non Segmental Vitiligo
This prospective, within subject clinical trial aims to evaluate the efficacy of combining fractional CO2 laser with topical methotrexate versus topical methotrexate alone in treating non-segmental vitiligo.
- Trial name
- NCT06877455
- Testing
- Fractional CO2 laser assisted PDT
- Volunteers
- 50 people
- Sponsor
- Assiut University
Glaucoma
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma
The aim of this study is to create a large-scale register of all glaucoma patients diagnosed, followed and treated in a large tertiary centre specialising in glaucoma, in order to analyse whether specific factors influence the…
- Trial name
- NCT06227299
- Where
- Switzerland
- Volunteers
- 5,000 people
- Sponsor
- Swiss Glaucoma Research Foundation
Postmenopausal Period, Vaginal Atrophy
Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser
The aim of study is characteristic of changes in the vaginal wall after treatment of neodymium laser radiation with a wavelength of 1064 nm.
- Conditions
- Postmenopausal Period, Vaginal Atrophy, Vaginal Prolapse
- Trial name
- NCT05335317
- Testing
- Laser Treatment, Topical hormone estriol, Сlinical blood analysis
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MeLSyTech, Ltd
Intrathoracic Lymphadenopathy
Optical Biopsy and Cytological Evaluation for Intrathoracic Lymphadenopathy
The purpose of this study is to describe and validate confocal laser endomicroscopy(CLE) and rapid on-site evaluation(ROSE) interpretation criteria for different types of intrathoracic lymphadenopathy.
- Trial name
- NCT07047417
- Testing
- CLE and ROSE
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shanghai Chest Hospital
Enlarged Prostate (BPH), Benign Prostatic Hyperplasia
Moses 2.0 vs Magneto for HoLEP - a Randomized Controlled Trial
The objective of this study is to compare the Magneto 150 holmium laser to the current MOSES 2.0 technology to see if there is a benefit in decreased hemostasis time intraoperatively.
- Trial name
- NCT07632742
- Testing
- Magneto 150 holmium laser, Moses 2.0 holmium laser
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Peri-implantitis
Evaluation of Fractalkine and Its Receptor in Peri-implantitis
In this study, mechanical debridement group, Er:YAG laser group and diode laser group will be compared in terms of reducing peri-implant sulcus depth in the treatment of peri-implantitis.
- Trial name
- NCT06685523
- Testing
- Subgingival debridement, Er:YAG laser decontamination, Diyot laser decontamination
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kubilay BARIŞ
Periodontitis
Low Laser Therapy and Hyaluronic Acid as an Adjunct to Non-surgical Periodontal Therapy
Periodontal disease is an oral disease characterized by microbially associated, host-mediated inflammation of the periodontium. In the treatment of periodontal disease, conventional periodontal therapy includes both surgical and…
- Trial name
- NCT05907161
- Testing
- SRP+LASER (Dentsply Sirona - SIROLaser Blue), SRP+HA, SRP
- Where
- Slovenia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess
SiLaC Laser Technique for Pilonidal Sinus - La Paz Cohort Study.
Pilonidal sinus disease (PSD) is a chronic inflammatory condition of the sacrococcygeal region that frequently affects young adults, often causing pain, drainage, and recurrent infection.
- Conditions
- Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess, Pilonidal Sinus, Pilonidal Cysts
- Trial name
- SiLaC-LaPaz (NCT07260643)
- Testing
- SilaC
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario La Paz
Burn, Hypertrophic Scars
Carbon Dioxide Laser-Assisted Delivery of Triamcinolone With or Without 5-Fluorouracil for Hypertrophic Burn Scars
Burn scars can sometimes heal in a way that causes them to become thick, raised, and stiff. These scars may itch, feel uncomfortable, limit movement, and affect how the skin looks.
- Conditions
- Burn, Hypertrophic Scars, Scar Improvement by Laser, CO2 Laser in Scars
- Trial name
- NCT07660120
- Testing
- Fractional Ablative CO₂ Laser, Triamcinolone Acetonide, Fluorouracil (5-FU)
- Volunteers
- 65 people
- Sponsor
- University of California, Davis
Frozen Sections, Indocyanine Green
Multi-center Study on CCeLL-In Vivo's Clinical Efficacy for Intraoperative Brain Tumor Diagnosis.
The primary objective of this study is to demonstrate the non-inferiority of cCeLL compared to frozen section analysis. The investigational device is intended for use with indocyanine green (ICG) for fluorescence imaging as an…
- Conditions
- Frozen Sections, Indocyanine Green, Brain Tumor
- Trial name
- PRECISION (NCT06867978)
- Testing
- cCeLL In vivo, Indocyanine Green
- Volunteers
- 100 people
- Sponsor
- VPIX Medical
Temporomandibular Joint Disorders
Clinical and Electromyographic Assessment of Occlusal Splint Therapy
Temporomandibular disorders (TMDs) cause pain and dysfunction in the masticatory system, often managed with occlusal splint therapy. However, splint therapy alone may yield inconsistent results.
- Trial name
- NCT07878247
- Testing
- Low Level Laser Therapy
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Future University in Egypt