Clinical trials: Lasers
Glaucoma
Water Drinking Test in Patients With Occludable Angle
The water drinking test (WDT), is a predictive test that has been used to detect primary open angle glaucoma and recently has been demonstrated as a predictor of the diurnal tension curve.
- Trial name
- NCT02613533
- Testing
- Intra-ocular pressure measurement (IOP)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wills Eye
Peri-Implantitis
Efficacy of Er: YSGG Laser in Treatment of Peri-implantitis
This study will be carried out to evaluate the efficacy of Er: YSGG laser on oral biofilm removal from implant surface in various peri-implant defect morphology in the treatment of peri-implantitis as a primary objective.
- Trial name
- NCT05137821
- Testing
- Er: YSGG laser, no therapy
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pilonidal Disease
Effectiveness of Laser Hair Removal in Pilonidal Disease
Pilonidal disease is a common painful condition that affects 26 per 100,000 people with an incidence of 1.1% in the young male population.
- Trial name
- NCT03276065
- Testing
- Laser depilation, Standard of care hair depilation
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- Nationwide Children's Hospital
Myopia, Astigmatism
Wavefront-guided PRK vs Wavefront-optimized PRK
The purpose of the study is to compare the results of PRKK surgery when using wavefront-guided excimer laser treatment compared to wavefront optimized excimer laser treatment in patients with nearsightedness with and without…
- Trial name
- NCT02091934
- Testing
- Wavefront-guided PRK, Wavefront-optimized PRK
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Stanford University
Epilepsy, Pulmonary Embolism
iMRI Prone Positioning Frame Design Feasibility Study
The goal of this study is to learn if the prototype adjustable prone positioning frame is a feasible design for use during neurosurgical procedures which utilize intraoperative magnetic resonance imaging (iMRI).
- Trial name
- NCT06388512
- Testing
- prototype prone positioning device
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Kansas Medical Center
Open-Angle Glaucoma, Ocular Hypertension
Selective, Micropulse and Pattern Laser Trabeculoplasty in Medically Treated Open-angle Glaucoma.
This randomized, single-centre, three-arm trial compared three subvisible laser trabeculoplasty delivery protocols in eyes with open-angle glaucoma already receiving intraocular pressure (IOP)-lowering medication: selective laser…
- Trial name
- NCT07756411
- Testing
- Selective laser trabeculoplasty, Micropulse laser trabeculoplasty, Pattern laser trabeculoplasty
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- University of Udine
Sacroiliac Joint Pain
High-intensity Laser Therapy for Sacroiliac Joint Pain
Effect of high intensity laser on sacroiliac joint pain
- Trial name
- Girls (NCT06262763)
- Testing
- Laser Therapy, Traditional exercises
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Glaucoma, Angle-Closure
Comparison of Superior vs Nasal/Temporal Laser Peripheral Iridotomy in Primary Angle Closure
The purpose of this study is to determine if location of laser peripheral iridotomy (LPI) that is the standard of care treatment for angle closure glaucoma is related to changes in post-operative intraocular pressure (IOP)…
- Trial name
- NCT03187821
- Testing
- Laser peripheral iridotomy
- Volunteers
- 1,000 people
- Sponsor
- Venkatesh Rengaraj
Telangiectasis, Erythema
Pulsed Dye Laser and Intense Pulsed Light (IPL) for the Treatment of Telangiectasia and Skin Redness
The purpose of the study is to compare efficacy and adverse effects of pulsed dye laser and intense pulsed light in patients with skin telangiectasia and redness.
- Trial name
- NCT00206921
- Testing
- Pulsed dye laser, Intense pulsed light
- Where
- Denmark
- Sponsor
- Bispebjerg Hospital
Aged Skin
Determination of Safety and Efficacy of a Laser With Cooling for Treatment of Skin
The appearance of aged skin is a common cosmetic complaint of middle aged and older individuals. This study evaluates the safety and efficacy of a new laser with cooling to improve the appearance of aged skin.
- Trial name
- NCT00323921
- Testing
- dermatological infrared laser
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Lichen Sclerosus
Laser vs Clobetasol for Lichen Sclerosus
Lichen sclerosus (LS) is a common autoimmune disease of the genital skin. It affects 1/900 women with an age peak in the sixth decade of life and is manifested by chronic inflammation of the genital, perineal, and perianal areas…
- Trial name
- NCT05010421
- Testing
- Clobetasol 0.05% Emollient Top Cream, Non-ablative CO2 Laser
- Where
- Germany
- Volunteers
- 246 people
- Sponsor
- Ruhr University of Bochum
Varicose Veins
The BRILLIANT Study
This trial was designed as a prospective, multi-center, randomized clinical trial of the FDA-cleared Vari-Lase Bright Tip Fiber compared to commercially available standard bare-tip laser fiber (control) to demonstrate the safety…
- Trial name
- BRILLIANT (NCT00618514)
- Testing
- Bright Tip Laser Fiber, Bare Tip Laser Fiber
- Where
- 7 sites in United States
- Volunteers
- 93 people
- Sponsor
- Vascular Solutions LLC
Must be PRK Candidate
A 6 Month Study to Evaluate the Safety, Analgesic Efficacy of ACUVAIL™ (Ketorolac Tromethamine Ophthalmic Solution) 0.45%, in Post-PRK Corneal Wound Healing
STUDY OBJECTIVE: To evaluate the safety and efficacy of Acuvail 0.45% administered BID for increasing corneal re-epithelialization, decreasing the time to zero pain in post-photorefractive keratectomy (PRK) surgery, and PRK…
- Trial name
- NCT01193231
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Durrie Vision
Systemic Lupus Erythematosus
Laser Puncture and Program of Lifestyle Modification in Lupus Females
Serum lipid profile was significantly dysregulated in female systemic lupus erythematosus (SLE) patients
- Trial name
- NCT05381545
- Testing
- laser puncture, energy expenditure programming, and low-calories recommended diet programming, energy expenditure programming and low-calories recommended diet programming
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Burn Injury
Efficacy of EPSW Plus HILT on Carpal Tunnel Syndrome Post Burn Injury
To study the effect of adding ESWT as a noninvasive short-term treatment plus high-level laser therapy for moderate carpal-tunnel syndrome post-burn injuries.
- Trial name
- NCT05876442
- Testing
- Extracorporeal Shock Wave Therapy., High Intensity Laser Therapy, Traditional Physical Therapy Exercise Program
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Periodontal Inflammation
The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups
the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients
- Trial name
- NCT06140394
- Testing
- diode laser, non surgical scaling
- Where
- 2 sites in Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness
To Assess Signs and Symptoms in Women Affected by GSM After One Cycle of Pixel CO2-Alma Fractionated Laser
Genitourinary syndrome of menopause (GSM) occurs in approximately 50% of menopausal women but is both underrecognized and undertreated despite numerous treatment options.
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness, Burning, Pain
- Trial name
- NCT05156502
- Testing
- Fractionated Laser (Pixel CO2-Alma), Fractionated Laser (Pixel CO.2-Alma)
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr. Filippo Murina
Manual Therapy, Myofascial Pain Syndrome
Plantar Pressures After Pressure Release of the Flexor Digitorum Brevis Muscle Versus a Non-emission Laser.
In this study we will test the effects of pressure release on the Flexor digitorum brevis muscle on the plantar pressures variables using a pressure platform.
- Conditions
- Manual Therapy, Myofascial Pain Syndrome, Foot, Flat Foot
- Trial name
- NCT06499545
- Testing
- Pressure release, Non emision Laser
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Varicose Veins
The Effect of Laser Power and Fiber Traction Speed on the Outcomes of Endovenous Laser Ablation
A multicenter clinical randomized controlled trial, comparing of three different regimens of endovenous laser ablation with equal linear endovenous energy density in patients with insufficiency of the great saphenous vein (GSV).
- Trial name
- SLEDGE (NCT03037827)
- Testing
- Endovenous laser ablation (EVLA), Laser
- Where
- 2 sites in Russia
- Volunteers
- 203 people
- Sponsor
- Clinic of Phlebology and Laser Surgery, Chelyabinsk, Russia
Intense Pulsed Light, Erbium-yttrium Aluminum Garnet Laser
Combined Intense Pulsed Light (IPL) With Fractional Erbium:YAG Laser Ablation in Scar Prevention
The scar site was divided into 3 sites; combined IPL/fractional Er:YAG laser treatment site, fractional Er:YAG laser treatment site and untreated control site.
- Conditions
- Intense Pulsed Light, Erbium-yttrium Aluminum Garnet Laser, Scar Prevention
- Trial name
- NCT04722705
- Testing
- fractional Er:YAG laser, Intense pulse light
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
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